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D

Daniel J. McGrail

Lerner Research Institute
H指数:35
被引数:4,730

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Tumor ecosystem and microbiome features associated with efficacy and resistance to avelumab plus chemoradiotherapy in head and neck cancer

头颈癌中与avelumab联合化放疗疗效及耐药性相关的肿瘤生态系统和微生物组特征

Nature Cancer
IF28.5
2026-01-020
PRE
Nadeem Riaz; Tyler J. Alban; Robert I. Haddad; Michelle Saul; Vladimir Makarov; Yingjie Zhu; Ezra E. W. Cohen; Robert L. Ferris; Peter Mu-Hsing Chang; Jin-Ching Lin; Amanda Psyrri; Prerana Bangalore Parthasarathy; Ardijana Novaj; Mruniya Gawali; Douglas Hoen; Phineas Hamilton; Natalie L. Silver; Ivan Juric; Daniel Chawla; Ana Gradissimo; Jennifer Ko; Daniel J. McGrail; Craig B. Davis; Nancy Y. Lee; Timothy A. Chan
Neutrophil to lymphocyte ratio varies in magnitude and biomarker utility based on patient demographics

Ang W, Kerr TD, Kodiboyena A, Valero C, Vos JL, Makarov V, 等. 中性粒细胞与淋巴细胞比值根据患者人口统计学特征在幅度和生物标志物效用方面存在差异。临床研究杂志。(2025)。doi: 10.1172/jci198948

Journal of Clinical Investigation
IF13.6
2026-01-022
OA
Ang, William; Kerr, Travis D.; Kodiboyena, Ananya; Valero, Cristina; Vos, Joris L.; Makarov, Vladimir; Adjei, Alex A.; Morris, Luc G. T.; Schmit, Stephanie L.; Silver, Natalie L.; Patil, Sujata; McGrail, Daniel J.
Intratumoral bacteria are immunosuppressive and promote immunotherapy resistance in head and neck squamous cell carcinoma

肿瘤内细菌具有免疫抑制性，并促进头颈部鳞状细胞癌的免疫治疗耐药性。

Nature Cancer
IF28.5
2026-01-020
OAAI
Natalie L. Silver; Jin Dai; Travis D. Kerr; Jessica Altemus; Rekha Garg; Hannah Simmons; Tyler Alban; Laura Noel-Romas; Vladimir Makarov; David J. H. Shih; Shwetha V. Kumar; Akeem Santos; Rehan Akbani; Adam Burgener; Mohammed Dwidar; Neil Gross; Andrew G. Sikora; Elias J. Sayour; Apollo Stacy; Christian Jobin; Timothy A. Chan; Renata Ferrarotto; Daniel J. McGrail
Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cycle

琥珀酸盐的积累通过琥珀酰化介导的控制线粒体叶酸循环来抑制从头嘌呤合成。

Molecular Cell
IF16.6
2025-10-280
PRE
Mushtaq A. Nengroo; Austin T. Klein; Heather S. Carr; Olivia Vidal-Cruchez; Umakant Sahu; Daniel J. McGrail; Nidhi Sahni; Niklas B. Thompson; Peter A. Faull; Peng Gao; John M. Asara; Hardik Shah; Marc L. Mendillo; Issam Ben-Sahra
Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell-Induced Ferroptosis in Ovarian Cancer

肿瘤内源性METTL5调控ATF4翻译以防止T细胞诱导的铁死亡在卵巢癌中发生

Advanced Science
IF14.1
2025-10-030
OAAI
Jiakai Hou; Cheng-Wei Ju; Nicholas A. Egan; Yanjun Wei; Yunfei Wang; Minghao Dang; Tianyi Zhou; Leilei Shi; Ningbo Zheng; Si Chen; Ashley M. Guerrero; Xiaofang Liang; Wanfu Wu; Areej Akhtar; Chitra Dhiman; Debanwita Roy Burman; Andro E. Gerges; Mason D. Flores; Han Li; Li-Sheng Zhang; Marleen Kok; Xiaobo Mao; Linghua Wang; Qin Feng; Yiwen Chen; Sanghoon Lee; Daniel J. McGrail; Nidhi Sahni; Chuan He; Amir A. Jazaeri; Weiyi Peng
Chemosensitization is not associated with improved adjuvant radiation outcomes for cutaneous squamous cell carcinoma: a dual-center retrospective cohort study

化学增敏与皮肤鳞状细胞癌辅助放疗结果的改善无关：一项双中心回顾性队列研究

Journal of the American Academy of Dermatology
IF11.8
2025-09-110
PRE
Emily E. Granger; Emily Y. Kim; Nina A. Ran; Karina Brito; David M. Wang; Ann W. Silk; Danielle N. Margalit; Roy B. Tishler; Jonathan D. Schoenfeld; Shauna Campbell; Allison Vidimos; Daniel McGrail; Shlomo Koyfman; Emily S. Ruiz
Exploring TROP2 expression in oropharyngeal squamous cell carcinoma: Association with prognosis and tumor immune microenvironment composition

探索TROP2在口咽鳞状细胞癌中的表达：与预后的关联及肿瘤免疫微环境组成的关联

Oral Oncology
IF3.9
2025-08-260
PRE
Juliana Mota Siqueira; Daniele Heguedusch; Mateus Trinconi Cunha; Luana Guimaraes de Sousa; Mario L. Marques-Piubelli; Giovanna Lopes Carvalho; Camilla Oliveira Hoff; Flavia Bonini; Yoshitsugu Mitani; Michael T. Spiotto; Ryan Goepfert; Fabio Daumas Nunes; Leandro Luongo Matos; Luiz Paulo Kowalski; Daniel J McGrail; Adel K. El-Naggar; Renata Ferrarotto
KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

KEAP1和STK11/LKB1突变增强KRAS突变非小细胞肺癌对ATR抑制的易感性

Cancer Cell
IF44.5
2025-07-100
OAAI
Ana Galan-Cobo; Natalie I. Vokes; Yu Qian; David Molkentine; Kavya Ramkumar; Alvaro G. Paula; Marlese Pisegna; Daniel J. McGrail; Alissa Poteete; Sungnam Cho; Minh Truong Do; Amirali Karimi; Yifan Kong; Anisha Solanki; Ankur Karmokar; Nicolas Floc’h; Adina Hughes; Rebecca Sargeant; Lucy Young; Li Shen; Gozde Kar; Caezaan Keshvani; Claudio Arrechedera; Sharia Hernandez; Katharina Schlacher; Jing Wang; Sonia Iyer; James Conway; Mohamed Reda Keddar; Marta Milo; Ilario de Toma; Susan E. Critchlow; J. Carl Barrett; Jan Cosaert; Alan Lau; Viia Valge-Archer; Lauren A. Byers; Simon T. Barry; John V. Heymach
TROP2 Expression in Salivary Gland Adenoid Cystic Carcinoma (ACC) According to Histologic Subtype: Therapeutic Implications

TROP2在唾液腺腺样囊性癌（ACC）中的表达：根据组织学亚型及其治疗意义

Journal of Oral Pathology & Medicine
IF2.3
2025-07-080
OA
Juliana Mota Siqueira; Yoshitsugu Mitani; Mario L. Marques-Piubelli; Camilla Oliveira Hoff; Flavia Bonini; Luana Guimaraes de Sousa; Mutsumi Mitani; Giovanna Lopes Carvalho; Fabio Daumas Nunes; Leandro Luongo Matos; Shiaw-Yih Lin; Michael T. Spiotto; Ehab Y. Hanna; Daniel J. McGrail; Adel K. El-Naggar; Renata Ferrarotto
Building research infrastructure to advance precision medicine in colorectal cancer

构建研究基础设施以推进结直肠癌精准医学

JNCI CANCER SPECTRUM
IF4.1
2025-06-010
OAAI
Schmit, Stephanie L.; Lorona, Nicole C.; Sobieski, Daniel; Matejcic, Marco; Nguyen, Nathalie T.; Hoehn, Hannah J.; Diaz, Diana B.; Shankar, Kritika; Cockman, Eric M.; Jean-Baptiste, Esther; Tsai, Ya-Yu; Buchalter, R. Blake; Brito, Karina; Wilson, Rusche; Coppola, Domenico; Fulmer, Clifton; Saglam, Ozlen; Tassielli, Alexandra F.; Beato, Francisca; Dai, Ruifan; Freedman, Jennifer A.; Purrington, Kristen; Hu, Bo; Mcgrail, Daniel; Gibson, Heather; Jiang, Kun; Munoz-Antonia, Teresita; Flores, Idhaliz; Gordian, Edna; Oliveras Torres, Jose A.; Cheng, Iona; Van Blarigan, Erin L.; Felder, Seth I.; Sanchez, Julian A.; Fleming, Jason B.; Siegel, Erin M.; Cress, Douglas; Thompson, Patricia; Stern, Mariana C.; Teer, Jamie K.; Figueiredo, Jane C.
UBA1 inhibition sensitizes cancer cells to PARP inhibitors

UBA1抑制使癌细胞对PARP抑制剂更敏感

CELL REPORTS MEDICINE
IF10.6
2024-12-011
PRE
Awasthi, Sharad; Dobrolecki, Lacey E.; Sallas, Christina; Zhang, Xudong; Li, Yang; Khazaei, Sima; Ghosh, Sumanta; Jeter, Collene R.; Liu, Jinsong; Mills, Gordon B.; Westin, Shannon N.; Lewis, Michael T.; Peng, Weiyi; Sood, Anil K.; Yap, Timothy A.; Yi, S. Stephen; McGrail, Daniel J.; Sahni, Nidhi
Clinical and biomarker analyses of intratumoral CD40 agonist sotigalimab in combination with pembrolizumab in metastatic melanoma: A phase I/II trial

在转移性黑色素瘤中，肿瘤内注射CD40激动剂sotigalimab联合pembrolizumab的临床与生物标志物分析：一项I/II期临床试验

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Bentebibel, S-E.; McGrail, D.; Wahab, R. Abdel; Kochat, V.; Arslan, E.; Pazdrak, B.; Tahon, N. H.; Amaria, R. N.; Glitza, I. C.; Patel, S.; Wong, M. K. K.; Tawbi, H. A.; Mcquade, J.; Davies, M.; Bernatchez, C.; Burks, J.; Rai, K.; Ekmekcioglu, S.; Lizee, L.; Diab, A.
Notch inhibitor AL101 prior to surgery in patients (pts) with Notch1 activated adenoid cystic carcinoma (ACC): Safety and efficacy in a window of opportunity study

Notch抑制剂AL101在Notch1激活的腺样囊性癌（ACC）患者术前治疗中的安全性及有效性：一项机会窗口研究

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Ferrarotto, R.; McGrail, D.; Mitani, Y.; Santos, E.; Johnson, F.; Chen, M.; Li, K.; Lin, S-Y; Frank, S.; Lee, J. J.; Williams, M.; Esmaeli, B.; El-Naggar, A.; Hanna, E.

研究方向

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N
Nidhi Sahni
H 指数:37论文数:197被引数:7,726
S
S. Stephen Yi
H 指数:29论文数:170被引数:5,684
S
Shiaw‐Yih Lin
H 指数:40论文数:227被引数:8,568
G
Gordon B. Mills
H 指数:231论文数:3,475被引数:26.3万
H
Hui Dai
H 指数:27论文数:147被引数:2,591
M
Michelle Dawson
H 指数:30论文数:330被引数:3,793
R
Renata Ferrarotto
H 指数:48论文数:483被引数:1.0万
S
Sharad Awasthi
H 指数:11论文数:27被引数:330
李永生 封面图
李永生
H 指数:48论文数:413被引数:8,352
杨丽 封面图
杨丽
H 指数:46论文数:488被引数:8,429