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M

Magdalini Polymenidou

University of Zurich
H指数:41
被引数:1.5万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Blocking RAN translation without altering repeat RNAs rescues C9ORF72-related ALS and FTD phenotypes

在不改变重复rna的情况下阻断RAN翻译可挽救C9ORF72-related ALS和FTD表型

Science
IF45.8
2026-02-050
PRE
Xin Jiang; Laure Schaeffer; Divya Patni; Tommaso Russo; Chao-Zong Lee; Corey Aguilar; Christine Marques; Karen Jansen-West; Marian Hruska-Plochan; Ananya Ray-Soni; Su Min Lim; Aaron Held; Mei Yue; Paula Castellanos Otero; Sandeep Aryal; Hortense D. A. M. Beaussant; Himanish Basu; Hiro Takakuwa; Lillian M. Daughrity; Nandini Ramesh; Paulo Da Costa; Ana Rita A. A. Quadros; Matthew Nolan; Charles Jourdan F. Reyes; Hayden Wheeler; Laura C. Moran; Grant Griesman; Benjamin Wymann; Bianca A. Trombetta; Emma Sofia Lopez-De-Silanes; Michael Canori; Gopinath Krishnan; Yasmim Vieira Souza Da Silva; Gilbert Eriani; Mark W. Albers; Steven E. Arnold; Yuyu Song; Ankur Jain; Isaac M. Chiu; Yong-Jie Zhang; Fen-Biao Gao; Brian J. Wainger; Magdalini Polymenidou; Leonard Petrucelli; Franck Martin; Clotilde Lagier-Tourenne
Development of [18F]ACI-19626 as a first-in-class brain PET tracer for imaging TDP-43 pathology

开发 [18F]ACI-19626作为一流的脑PET示踪剂，用于TDP-43病理学成像

Nature Communications
IF15.7
2025-10-240
OAAI
Efthymia Vokali; Elodie Chevalier; Nicolas Dreyfus; Dorian Charmey; Tania Melly; Jacqueline Kocher; Monisha Ratnam; Andreia M. Serra; Thomas Jaquier; Christophe Delgado; Myriam Ravache; Carlo Scialò; Sara Cappelli; Heiko Kroth; Francesca Capotosti; Ruth Luthi-Carter; Tariq Afroz; Madiha Derouazi; Cristian C. Constantinescu; Harro Seelaar; Emanuele Buratti; Peter T. Nelson; Magdalini Polymenidou; Andrea Pfeifer; Marie Kosco-Vilbois; Tamara Seredenina
The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
EMBO MOLECULAR MEDICINE
IF8.3
2024-07-302
OAAI
Losa, Marco; Emmenegger, Marc; De Rossi, Pierre; Schuerch, Patrick M.; Serdiuk, Tetiana; Pengo, Niccolo; Capron, Danaelle; Bieli, Dimitri; Bargenda, Niklas; Rupp, Niels J.; Carta, Manfredi C.; Frontzek, Karl J.; Lysenko, Veronika; Reimann, Regina R.; Schwarz, Petra; Nuvolone, Mario; Westermark, Gunilla T.; Nilsson, K. Peter R.; Polymenidou, Magdalini; Theocharides, Alexandre P. A.; Hornemann, Simone; Picotti, Paola; Aguzzi, Adriano
Detection of TDP-43 seeding activity in the olfactory mucosa from patients with frontotemporal dementia

检测额颞叶痴呆患者嗅粘膜中的TDP-43播种活性

ALZHEIMERS & DEMENTIA
IF11.1
2023-10-315
OA
Fontana, Elena; Bongianni, Matilde; Benussi, Alberto; Bronzato, Erika; Scialo, Carlo; Sacchetto, Luca; Cagnin, Annachiara; Castriciano, Santina; Buratti, Emanuele; Gardoni, Fabrizio; Italia, Maria; Schreiber, Alberto; Ferracin, Chiara; Fiorini, Michele; Newell, Kathy L.; Cracco, Laura; Garringer, Holly J.; Cecchini, Maria Paola; Polymenidou, Magdalini; Padovani, Alessandro; Monaco, Salvatore; Legname, Giuseppe; Ghetti, Bernardino; Borroni, Barbara; Zanusso, Gianluigi
Loss of TDP-43 oligomerization or RNA binding elicits distinct aggregation patterns
EMBO JOURNAL
IF8.3
2023-07-1121
OAAI
Perez-Berlanga, Manuela; Wiersma, Vera, I; Zbinden, Aurelie; De Vos, Laura; Wagner, Ulrich; Foglieni, Chiara; Mallona, Izaskun; Betz, Katharina M.; Clery, Antoine; Weber, Julien; Guo, Zhongning; Rigort, Ruben; de Rossi, Pierre; Manglunia, Ruchi; Tantardini, Elena; Sahadevan, Sonu; Stach, Oliver; Hruska-Plochan, Marian; Allain, Frederic H-T; Paganetti, Paolo; Polymenidou, Magdalini
Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease

人源性抗poly-ga抗体在C9orf72疾病细胞和动物模型中的综合评价

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-12-015
OAAI
Jambeau, Melanie; Meyer, Kevin D.; Hruska-Plochan, Marian; Tabet, Ricardos; Lee, Chao-Zong; Ray-Soni, Ananya; Aguilar, Corey; Savage, Kitty; Mishra, Nibha; Cavegn, Nicole; Borter, Petra; Lin, Chun-Chia; Jansen-West, Karen R.; Jiang, Jie; Freyermuth, Fernande; Lia, Nan; De Rossi, Pierre; Perez-Berlanga, Manuela; Jiang, Xin; Daughrity, Lilian M.; Pereira, Joao; Narayanan, Sarav; Gu, Yuanzheng; Dhokai, Shekhar; Dalkilic-Liddle, Isin; Maniecka, Zuzanna; Weber, Julien; Workman, Michael; McAlonis-Downes, Melissa; Berezovski, Eugene; Zhang, Yong-Jie; Berry, James; Wainger, Brian J.; Kankel, Mark W.; Rushe, Mia; Hock, Christoph; Nitsch, Roger M.; Cleveland, Don W.; Petrucelli, Leonard; Gendron, Tania F.; Montrasio, Fabio; Grimm, Jan; Polymenidou, Magdalini; lagier-Tourenne, Clotilde
FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade
EMBO REPORTS
IF6.2
2021-11-2214
OA
De Rossi, Pierre; Lewis, Amanda J.; Furrer, Johanna; De Vos, Laura; Demeter, Tomas; Zbinden, Aurelie; Zhong, Weijia; Wiersma, Vera, I; Scialo, Carlo; Weber, Julien; Guo, Zhongning; Scaramuzza, Stefano; Di Fabrizio, Marta; Boeing, Carolin; Castano-Diez, Daniel; Al-Amoudi, Ashraf; Perez-Berlanga, Manuela; Lashley, Tammaryn; Stahlberg, Henning; Polymenidou, Magdalini
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies

LAG3在人和鼠神经元中不表达，并且不调节 α-突触核蛋白病

EMBO MOLECULAR MEDICINE
IF8.3
2021-07-2652
OAAI
Emmenegger, Marc; De Cecco, Elena; Hruska-Plochan, Marian; Eninger, Timo; Schneider, Matthias M.; Barth, Melanie; Tantardini, Elena; de Rossi, Pierre; Bacioglu, Mehtap; Langston, Rebekah G.; Kaganovich, Alice; Bengoa-Vergniory, Nora; Gonzalez-Guerra, Andres; Avar, Merve; Heinzer, Daniel; Reimann, Regina; Haesler, Lisa M.; Herling, Therese W.; Matharu, Naunehal S.; Landeck, Natalie; Luk, Kelvin; Melki, Ronald; Kahle, Philipp J.; Hornemann, Simone; Knowles, Tuomas P. J.; Cookson, Mark R.; Polymenidou, Magdalini; Jucker, Mathias; Aguzzi, Adriano
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects
NATURE COMMUNICATIONS
IF15.7
2021-05-2131
OAAI
Scekic-Zahirovic, Jelena; Sanjuan-Ruiz, Inmaculada; Kan, Vanessa; Megat, Salim; De Rossi, Pierre; Dieterle, Stephane; Cassel, Raphaelle; Jamet, Marguerite; Kessler, Pascal; Wiesner, Diana; Tzeplaeff, Laura; Demais, Valerie; Sahadevan, Sonu; Hembach, Katharina M.; Muller, Hans-Peter; Picchiarelli, Gina; Mishra, Nibha; Antonucci, Stefano; Dirrig-Grosch, Sylvie; Kassubek, Jan; Rasche, Volker; Ludolph, Albert; Boutillier, Anne-Laurence; Roselli, Francesco; Polymenidou, Magdalini; Lagier-Tourenne, Clotilde; Liebscher, Sabine; Dupuis, Luc

研究方向

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A
Adriano Aguzzi
H 指数:123论文数:883被引数:6.1万
D
Don W. Cleveland
H 指数:165论文数:532被引数:10.1万
M
Marián Hruška-Plocháň
H 指数:18论文数:39被引数:1,468
P
Pierre De Rossi
H 指数:18论文数:41被引数:1,914
C
Clotilde Lagier‐Tourenne
H 指数:48论文数:99被引数:1.4万
M
Manuela Pérez‐Berlanga
H 指数:11论文数:24被引数:1,466
S
Simone Hornemann
H 指数:39论文数:150被引数:8,543
P
Petra Schwarz
H 指数:46论文数:112被引数:9,098
V
Vera I. Wiersma
H 指数:8论文数:26被引数:350
C
Carlo Scialò
H 指数:19论文数:34被引数:847