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J

Jonathan Chou

University of California San Francisco
H指数:33
被引数:1.0万

个人简介

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工作经历

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荣誉奖项

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Autophagolysosomal exocytosis inverts Src kinase onto the cell surface in cancer

自噬溶酶体胞吐作用将Src激酶反转到癌症的细胞表面

Science
IF45.8
2026-03-120
PRE
Corleone S. Delaveris; Rita P. Loudermilk; Apurva Pandey; Soumya G. Remesh; Trenton M. Peters-Clarke; Snehal D. Ganjave; William J. N. Dougherty; Henry M. Delavan; Chunyue Wang; Jesse Ling; Juan Antonio Camara Serrano; Fernando Salangsang; Chien-Kuang Cornelia Ding; Nancy Greenland; Carissa E. Chu; Sima Porten; Veronica Steri; Jonathan Chou; Michael J. Evans; Kevin K. Leung; James A. Wells
Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer

基因组规模CRISPR筛选确定PTGES3为晚期前列腺癌雄激素受体功能的直接调节因子

Nature Genetics
IF29
2025-11-050
OAAI
Haolong Li; James E. Melnyk; Becky Xu Hua Fu; Raunak Shrestha; Meng Zhang; Martin Sjöström; Siyu Feng; Jasmine A. Anderson; Wanting Han; Lisa N. Chesner; Hyun Jin Shin; Tatyanah Farsh; Humberto J. Suarez; Seema Nath; Jonathan Chou; Rajdeep Das; Emily A. Egusa; Marsha Calvert; Audrey Kishishita; Abhilash Barpanda; Jun Zhu; Ashutosh Maheshwari; William S. Chen; Mohammed Alshalalfa; Aidan Winters; Junjie T. Hua; Tianyi Liu; Elai Davicioni; Arun P. Wiita; Bradley A. Stohr; Javed Siddiqui; Bo Huang; Eric J. Small; Kevan M. Shokat; Peter S. Nelson; David A. Quigley; Elizabeth V. Wasmuth; Luke A. Gilbert; Felix Y. Feng
Modulating the PPARγ pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer

通过调节PPARγ通路上调NECTIN4，并增强膀胱癌中嵌合抗原受体（CAR）T细胞疗法。Nat. Commun. 16 (1), 8215

Nature Communications
IF15.7
2025-09-100
OAAI
Kevin Chang; Henry M. Delavan; Elizabeth Yip; Corynn Kasap; Jun Zhu; Roshan Lodha; Sheng-You Liao; Sarah C. Berman; Alberto Carretero-Gonzalez; Merve Basar; Gamze Gokturk Ozcan; Min Yuen Teo; David B. Solit; Jonathan E. Rosenberg; Hikmat Al-Ahmadie; Cornelia C. K. Ding; Emily Chan; Veronica Steri; Sima P. Porten; Vadim S. Koshkin; Terence W. Friedlander; Felix Y. Feng; John K. Lee; Arun P. Wiita; Carissa E. Chu; Jonathan Chou
CDK12 loss drives prostate cancer progression, transcription-replication conflicts, and synthetic lethality with paralog CDK13
CELL REPORTS MEDICINE
IF10.6
2024-10-010
OAAI
Tien, Jean Ching-Yi; Luo, Jie; Chang, Yu; Zhang, Yuping; Cheng, Yunhui; Wang, Xiaoju; Yang, Jianzhang; Mannan, Rahul; Mahapatra, Somnath; Shah, Palak; Wang, Xiao-Ming; Todd, Abigail J.; Eyunni, Sanjana; Cheng, Caleb; Rebernick, Ryan J.; Xiao, Lanbo; Bao, Yi; Neiswender, James; Brough, Rachel; Pettitt, Stephen J.; Cao, Xuhong; Miner, Stephanie J.; Zhou, Licheng; Wu, Yi-Mi; Labanca, Estefania; Wang, Yuzhuo; Parolia, Abhijit; Cieslik, Marcin; Robinson, Dan R.; Wang, Zhen; Feng, Felix Y.; Chou, Jonathan; Lord, Christopher J.; Ding, Ke; Chinnaiyan, Arul M.
PET Imaging Using 89Zr-Labeled StarPEG Nanocarriers Reveals Heterogeneous Enhanced Permeability and Retention in Prostate Cancer
MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-09-271
OAAI
Meher, Niranjan; Bidkar, Anil P.; Wadhwa, Anju; Bobba, Kondapa Naidu; Dhrona, Suchi; Dasari, Chandrashekhar; Mu, Changhua; Fong, Cyril O. Y.; Camara, Juan A.; Ali, Umama; Basak, Megha; Bulkley, David; Steri, Veronica; Fontaine, Shaun D.; Zhu, Jun; Oskowitz, Adam; Aggarwal, Rahul R.; Sriram, Renuka; Chou, Jonathan; Wilson, David M.; Seo, Youngho; Santi, Daniel V.; Ashley, Gary W.; Vanbrocklin, Henry F.; Flavell, Robert R.
Synthetic Lethal Targeting of CDK12-Deficient Prostate Cancer with PARP Inhibitors
CLINICAL CANCER RESEARCH
IF10.2
2024-09-251
PRE
Chou, Jonathan; Robinson, Troy M.; Egusa, Emily A.; Lodha, Roshan; Zhang, Meng; Badura, Michelle; Mikayelyan, Mane; Delavan, Henry M.; Swinderman, Jason; Wilson, Chris; Zhu, Jun; Das, Rajdeep; Nguyen, Minh; Loehr, Andrea; Golsorkhi, Tony; Simmons, Andrew; Abida, Wassim; Chinnaiyan, Arul M.; Arkin, Michelle R.; Small, Eric J.; Quigley, David A.; Yang, Lixing; Kim, Minkyu; Ashworth, Alan; Feng, Felix Y.
CDK12 loss promotes prostate cancer development while exposing vulnerabilities to paralog-based synthetic lethality
MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-06-100
PRE
Tien, Jean C.; Chang, Yu; Zhang, Yuping; Chou, Jonathan; Cheng, Yunhui; Wang, Xiaoju; Yang, Jianzhang; Mannan, Rahul; Shah, Palak; Wang, Xiao-Ming; Todd, Abbey; Eyunni, Sanjana; Cheng, Caleb; Cao, Xuhong; Bao, Yi; Neiswender, James; Brough, Rachel; Pettitt, Stephen; Labanca, Estefania; Wang, Yuzhuo; Cieslik, Marcin; Lord, Christopher J.; Ding, Ke; Chinnaiyan, Arul M.
Evaluating Immune Checkpoint Blockade in Metastatic Castration-Resistant Prostate Cancers with Deleterious CDK12 Alterations in the Phase 2 IMPACT Trial
CLINICAL CANCER RESEARCH
IF10.2
2024-05-245
PRE
Nguyen, Charles B.; Reimers, Melissa A.; Perera, Chamila; Abida, Wassim; Chou, Jonathan; Feng, Felix Y.; Antonarakis, Emmanuel S.; Mckay, Rana R.; Pachynski, Russell K.; Zhang, Jingsong; Reichert, Zachery R.; Palmbos, Phillip L.; Caram, Megan E. V.; Vaishampayan, Ulka N.; Heath, Elisabeth I.; Hopkins, Alexander C.; Cieslik, Marcin P.; Wu, Yi-Mi; Robinson, Dan R.; Baladandayuthapani, Veerabhadran; Chinnaiyan, Arul M.; Alva, Ajjai S.
The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer
CANCER RESEARCH
IF16.6
2023-06-0817
OAAI
Lundberg, Arian; Zhang, Meng; Aggarwal, Rahul; Li, Haolong; Zhang, Li; Foye, Adam; Sjostrom, Martin; Chou, Jonathan; Chang, Kevin; Moreno-Rodriguez, Thaidy; Shrestha, Raunak; Baskin, Avi; Zhu, Xiaolin; Weinstein, Alana S.; Younger, Noah; Alumkal, Joshi J.; Beer, Tomasz M.; Chi, Kim N.; Evans, Christopher P.; Gleave, Martin; Lara, Primo N.; Reiter, Rob E.; Retting, Matthew B.; Witte, Owen N.; Wyatt, Alexander W.; Feng, Felix Y.; Small, Eric J.; Quigley, David A.
Genomic and epigenomic drivers of double-negative metastatic prostate cancer
CANCER RESEARCH
IF16.6
2023-06-020
PRE
Lundberg, Arian; Zhang, Meng; Aggarwal, Rahul R.; Li, Haolong; Zhang, Li; Foye, Adam; Sjostrom, Martin; Chou, Jonathan; Chang, Kevin; Moreno-Rodriguez, Thaidy; Shrestha, Raunak; Baskin, Avi; Zhu, Xiaolin; Weinstein, Alana S.; Younger, Noah; Alumkal, Joshi J.; Beer, Tomasz M.; Chi, Kim N.; Evans, Christopher P.; Gleave, Martin; Lara, Primo N.; Reiter, Robert E.; Rettig, Matthew B.; Witte, Owen N.; Wyatt, Alexander W.; Feng, Felix Y.; Small, Eric J.; Quigley, David A.
Genome-wide CRISPR screens identify PTGES3 as a druggable AR modulator
CANCER RESEARCH
IF16.6
2023-06-020
PRE
Li, Haolong; Melnyk, James E.; Fu, Becky Xu Hua; Feng, Siyu; Sjostrom, Martin; Shrestha, Raunak; Zhang, Meng; Chesner, Lisa N.; Shin, Hyun Jin; Calvert, Marsha; Chou, Jonathan; Das, Rajdeep; Egusa, Emily A.; Winters, Aidan; Zhu, Jun; Maheshwari, Ashutosh; Hua, Junjie T.; Alshalalfa, Mohammed; Chen, William S.; Stohr, Bradley A.; Siddiqui, Javed; Huang, Bo; Small, Eric J.; Quigley, David A.; Shokat, Kevan M.; Gilbert, Luke A.; Feng, Felix Y.
Somatic alterations of TP53 and MDM2 associated with response to enfortumab vedotin in patients with advanced urothelial cancer

TP53和MDM2的体细胞改变与晚期尿路上皮癌患者对enfortumab vedotin的反应相关

FRONTIERS IN ONCOLOGY
IF3.3
2023-04-058
OAAI
Jindal, Tanya; Zhu, Xiaolin; Bose, Rohit; Kumar, Vipul; Maldonado, Edward; Deshmukh, Prianka; Shipp, Chase; Feng, Stephanie; Johnson, Michelle S.; Angelidakis, Austin; Kwon, Daniel; Borno, Hala T.; de Kouchkovsky, Ivan; Desai, Arpita; Aggarwal, Rahul; Fong, Lawrence; Small, Eric J.; Wong, Anthony; Porten, Sima; Chou, Jonathan; Friedlander, Terence; Koshkin, Vadim S.

研究方向

暂未获取到该数据
F
Felix Y. Feng
H 指数:109论文数:1,737被引数:5.0万
E
Eric J. Small
H 指数:118论文数:1,322被引数:6.8万
Z
Zena Werb
H 指数:168论文数:582被引数:14.3万
R
Rahul Aggarwal
H 指数:48论文数:937被引数:1.0万
D
David A. Quigley
H 指数:40论文数:441被引数:6,006
V
Vadim S. Koshkin
H 指数:29论文数:280被引数:5,205
张
张丽
H 指数:112论文数:4,086被引数:7.4万
T
Terence W. Friedlander
H 指数:35论文数:382被引数:8,143
M
Martin Sjöström
H 指数:29论文数:481被引数:3,292
B
Bradley A. Stohr
H 指数:25论文数:205被引数:3,106