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J

Jerry M. Adams

seoul national university (snu)

H指数:105

被引数:6.1万

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Mis-expression of GATA6 re-programs cell fate during early hematopoiesis

IF6.9

2024-05-010

OAAI

Bcl-2 retards cell cycle entry through p27Kip1, pRB relative p130, and altered E2F regulation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28139

OAAI

Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27109

OAAI

BAX mitochondrial integration is regulated allosterically by its α1-α2 loop

CELL DEATH AND DIFFERENTIATION

IF15.4

2021-06-169

OAAI

Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target

CELL DEATH & DISEASE

IF9.6

2020-04-2328

OAAI

Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma

IF7.3

2019-11-2617

PREAI

BAX and BAK become killers without a BH3 trigger

IF25.9

2019-11-1515

OAAI

BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association

IF6.9

2019-04-0146

OAAI

By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737

CELL DEATH AND DIFFERENTIATION

IF15.4

2018-12-1115

OAAI

The BCL-2 arbiters of apoptosis and their growing role as cancer targets

CELL DEATH AND DIFFERENTIATION

IF15.4

2017-11-03451

OAAI

Targeting BCL-2-like Proteins to Kill Cancer Cells

TRENDS IN CANCER

IF17.5

2016-08-01122

PREAI

Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis

CELL DEATH & DISEASE

IF9.6

2016-03-1019

OAAI

Donald Metcalf: The father of modern hematology

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-02-022

OAAI

Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-09-16106

OAAI

Functional antagonism between pro-apoptotic BIM and anti-apoptotic BCL-XL in MYC-induced lymphomagenesis

IF7.3

2014-05-2622

OAAI

NMR studies of interactions between Bax and BH3 domain-containing peptides in the absence and presence of CHAPS

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2014-03-0112

PREAI

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

BCL-2蛋白家族对细胞凋亡的控制: 对生理学和治疗的影响

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2013-12-202.8K

PREAI

Enhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis

Mcl1的增强的稳定性，一种促生存的Bcl2相对，抑制应激诱导的细胞凋亡，导致雄性不育，并促进肿瘤发生

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-12-2041

OA

Discovery of Potent and Selective Benzothiazole Hydrazone Inhibitors of Bcl-XL

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2013-06-2675

PREAI

Structure-guided design of a selective BCL-XL inhibitor

NATURE CHEMICAL BIOLOGY

IF13.7

2013-04-21379

PRE