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D

Douglas K. Graham

Emory University School of Medicine

43H指数
313论文数
6.6K被引数
收录论文 84
发表时间
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Free-floating long-term vascularized mesenchymal organoids游离的长期血管化间充质类器官
erriScience
IF4.1
err2025-12-26
err0
errOAAI
errAlejandro de Janon; Pranitha Kaza; Kaede Yoshida; SooJung Lee; Deborah DeRyckere; Douglas K. Graham; Shuichi Takayama
err分享
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Correction: Longitudinal single-cell analysis reveals treatment-resistant stem and mast cells with potential treatments for pediatric AML更正：纵向单细胞分析揭示了具有潜在治疗方法的儿童AML治疗抵抗性干细胞和肥大细胞。
errLeukemia
IF13.4
err2025-09-19
err0
PREAI
errDenis Ohlstrom; Mojtaba Bakhtiari; Hope Mumme; Marina Michaud; Alejandro De Janon Gutierrez; Deborah DeRyckere; Katherine E. Ferguson; Frank Chien; William Pilcher; Sarthak Satpathy; Sean Jordan; Douglas Graham; Swati Bhasin; Manoj Bhasin
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Longitudinal single-cell analysis reveals treatment-resistant stem and mast cells with potential treatments for pediatric AML纵向单细胞分析揭示了具有潜在治疗方法的儿童AML耐药性干细胞和肥大细胞
errLeukemia
IF13.4
err2025-09-10
err0
PREAI
errDenis Ohlstrom; Mojtaba Bakhtia; Hope Mumme; Marina Michaud; Alejandro De Janon Gutierrez; Deborah DeRyckere; Katherine E. Ferguson; Frank Chien; William Pilcher; Sarthak Satpathy; Sean Jordan; Douglas Graham; Swati Bhasin; Manoj Bhasin
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Prospects of current AXL-targeting therapies in early phase cancer trials当前AXL靶向疗法在早期癌症试验中的前景
errExpert Opinion on Investigational Drugs
IF4.1
err2025-05-31
err0
PREAI
errJuhye Yim; Chloe Hope; Justus M. Huelse; Douglas K. Graham
err分享
err收藏
Identification of leukemia-enriched signature through the development of a comprehensive pediatric single-cell atlas通过构建全面的儿科单细胞图谱识别白血病富集特征
errNATURE COMMUNICATIONS
IF15.7
err2025-05-02
err1
errOAAI
errMumme, Hope L.; Huang, Chenbin; Ohlstrom, Denis; Bakhtiari, Mojtaba; Raikar, Sunil S.; DeRyckere, Deborah; Qayed, Muna; Castellino, Sharon M.; Wechsler, Daniel S.; Porter, Christopher C.; Graham, Douglas K.; Bhasin, Swati S.; Bhasin, Manoj
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Discovery of Novel TYRO3/MERTK Dual Inhibitors新型TYRO3/MERTK双抑制剂的发现
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-04-11
err0
PREAI
errKong, Deyu; Zhao, Jichen; Huang, Daowei; Stashko, Michael A.; Yan, Dan; Ding, Ransheng; Guduru, Shiva K. R.; Zhou, Yubai; Kania, Catherine E.; Earp III, H. Shelton; Frye, Stephen V.; Huelse, Justus M.; Kireev, Dmitri; Deryckere, Deborah; Graham, Douglas K.; Wang, Xiaodong
err分享
err收藏
UNC9426, a Potent and Orally Bioavailable TYRO3-Specific InhibitorUNC9426，一种强效且口服生物利用度高的TYRO3特异性抑制剂
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-03-12
err0
PREAI
errKong, Deyu; Yang, Xiangbo; Judd, Samantha; Yan, Dan; Springborn, Stephanie; Stashko, Michael A.; Kidwell, Adam; Huelse, Justus M.; Kireev, Dmitri; Graham, Douglas K.; Deryckere, Deborah; Branchford, Brian
err分享
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MERTK inhibition selectively activates a DC - T-cell axis to provide anti-leukemia immunity
errLEUKEMIA
IF13.4
err2024-09-25
err0
PREAI
errHuelse, Justus M.; Bhasin, Swati S.; Jacobsen, Kristen M.; Yim, Juhye; Thomas, Beena E.; Branella, Gianna M.; Bakhtiari, Mojtaba; Chimenti, Madison L.; Baxter, Travon A.; Raikar, Sunil S.; Wang, Xiaodong; Frye, Stephen V.; Henry, Curtis J.; Earp, H. Shelton; Bhasin, Manoj; DeRyckere, Deborah; Graham, Douglas K.
err分享
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Discovery of Novel Macrocyclic MERTK/AXL Dual Inhibitors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-04-01
err2
PREAI
errKong, Deyu; Tian, Qiang; Chen, Zhilong; Zheng, Hongchao; Stashko, Michael A.; Yan, Dan; Earp, H. Shelton; Frye, Stephen V.; Deryckere, Deborah; Kireev, Dmitri; Graham, Douglas K.; Wang, Xiaodong
err分享
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PIM kinase inhibition synergizes with a MERTK inhibitor to treat osimertinib resistant EGFR-mutant non-small cell lung cancer
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errYan, Dan; Wang, Xiaodong; Frye, Stephen V.; Earp, H. Shelton; DeRyckere, Deborah; Graham, Douglas K.
err分享
err收藏
Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia
errNATURE COMMUNICATIONS
IF15.7
err2023-10-05
err10
errOAAI
errMumme, Hope; Thomas, Beena E.; Bhasin, Swati S.; Krishnan, Upaasana; Dwivedi, Bhakti; Perumalla, Pruthvi; Sarkar, Debasree; Ulukaya, Gulay B.; Sabnis, Himalee S.; Park, Sunita I.; Deryckere, Deborah; Raikar, Sunil S.; Pauly, Melinda; Summers, Ryan J.; Castellino, Sharon M.; Wechsler, Daniel S.; Porter, Christopher C.; Graham, Douglas K.; Bhasin, Manoj
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Constitutively Synergistic Multiagent Drug Formulations Targeting MERTK, FLT3, and BCL-2 for Treatment of AML
errPHARMACEUTICAL RESEARCH
IF4.3
err2023-09-13
err0
PREAI
errKelvin, James M.; Jain, Juhi; Thapa, Aashis; Qui, Min; Birnbaum, Lacey A.; Moore, Samuel G.; Zecca, Henry; Summers, Ryan J.; Switchenko, Jeffrey M.; Costanza, Emma; Uricoli, Biaggio; Wang, Xiaodong; Jui, Nathan T.; Fu, Haian; Du, Yuhong; Deryckere, Deborah; Graham, Douglas K.; Dreaden, Erik C.
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In vitro vascular differentiation system efficiently produces natural killer cells for cancer immunotherapies
errONCOIMMUNOLOGY
IF6.3
err2023-09-12
err3
errOAAI
errGalat, Yekaterina; Du, Yuchen; Perepitchka, Mariana; Li, Xiao-Nan; Balyasnikova, Irina, V; Tse, William T.; Dambaeva, Svetlana; Schneiderman, Sylvia; Iannaccone, Philip M.; Becher, Oren; Graham, Douglas K.; Galat, Vasiliy
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TAM family kinases as therapeutic targets at the interface of cancer and immunityTAM家族激酶作为癌症和免疫界面的治疗靶点
errNATURE REVIEWS CLINICAL ONCOLOGY
IF82.2
err2023-09-04
err21
PREAI
errDeryckere, Deborah; Huelse, Justus M.; Earp, H. Shelton; Graham, Douglas K.
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Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis
errSCIENTIFIC REPORTS
IF3.9
err2023-08-02
err3
errOAAI
errBhasin, Swati S.; Thomas, Beena E.; Summers, Ryan J.; Sarkar, Debasree; Mumme, Hope; Pilcher, William; Emam, Mohamed; Raikar, Sunil S.; Park, Sunita I.; Castellino, Sharon M.; Graham, Douglas K.; Bhasin, Manoj K.; DeRyckere, Deborah
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TAM receptor tyrosine kinase MERTK as a therapeutic target in the tumor immune microenvironment in a murine Kras mutant lung cancer model
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-05-01
err0
errOAAI
errYan, Dan; Wang, Xiaodong; Frye, Stephen; Earp, H. Shelton; DeRyckere, Deborah; Graham, Douglas K.
err分享
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Targeting a positive feedback loop of MERTK and STAT3 during macrophage differentiation may provide anti-tumor immune function
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errYan, Dan; Huelse, Justus M.; Bhasin, Swati Sharma; Bhasin, Manoj; DeRyckere, Deborah; Graham, Douglas K.
err分享
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Phosphorylation of MERTK is required for nuclear localization in non-small cell lung cancer (NSCLC)
errCANCER RESEARCH
IF16.6
err2023-04-04
err2
PREAI
errTanim, K. M.; DeRyckere, Deborah; Graham, Douglas K.
err分享
err收藏
Inhibiting efferocytosis reverses macrophage-mediated immunosuppression in the leukemia microenvironment抑制白血病微环境中巨噬细胞介导的免疫抑制
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-03-07
err13
errOAAI
errCruz, Joselyn Cruz; Allison, Kristen C.; Page, Lauren S.; Jenkins, Alexis J.; Wang, Xiaodong; Earp, H. Shelton; Frye, Stephen V.; Graham, Douglas K.; Verneris, Michael R.; Lee-Sherick, Alisa B.
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MERTK activation drives osimertinib resistance in EGFR-mutant non small cell lung cancer
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2022-08-01
err19
errOAAI
errYan, Dan; Huelse, Justus M.; Kireev, Dmitri; Tan, Zikang; Chen, Luxiao; Goyal, Subir; Wang, Xiaodong; Frye, Stephen, V; Behera, Madhusmita; Schneider, Frank; Ramalingam, Suresh S.; Owonikoko, Taofeek; Earp, H. Shelton; DeRyckere, Deborah; Graham, Douglas K.
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研究方向

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合作学者
合作期刊
C
Christopher P. Cannon
H 指数: 154 · 论文数: 1.4K
P
Peter M. Henson
H 指数: 128 · 论文数: 472
S
Suresh S. Ramalingam
H 指数: 124 · 论文数: 1.2K
K
Keith L. Ligon
H 指数: 113 · 论文数: 1.2K
A
Andrew L. Kung
H 指数: 105 · 论文数: 956
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