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Targeting Oxalate Production by Combining Enzyme Inhibition and Proteolysis Activation: A Novel Therapeutic Approach for Primary Hyperoxaluria Type 1 通过结合酶抑制和蛋白水解激活来靶向草酸盐的产生: 1型原发性高草酸尿症的新治疗方法 Arias, Fabio; Rohilla, Sumati; Sixto-Lopez, Yudibeth; Richard, Koral S. E.; Das, Sandeep; Anand, Sumit K.; Luque-Navarro, Pilar Maria; Banuelos-Sanchez, Guillermo; Pacheco-Garcia, Juan Luis; Gade, Reethika; Mckinney, M. Peyton; Kumar, Dhananjay; Maxie, Jemiah; Corr, W. Rylan; Pandey, Nilesh; Kaur, Harpreet; Ding, Jibin; Tan, Lin; Scott, Elisha; Nam, Hyung; Gottlieb, Eyal; Orr, A. Wayne; Dhanesha, Nirav; Yurdagul Jr, Arif; Pey, Angel L.; Franco-Montalban, Francisco; Gomez Vidal, Jose A.; Rom, Oren; Diaz-Gavilan, Monica 分享 收藏
A step-by-step guide to performing cancer metabolism research using custom-made media 使用定制培养基进行肿瘤代谢研究的分步指南 Seifert, Sophie; Yanqui-Rivera, Francisco; Kuhn, Tim; Hoyland, Lena Elise; Bortecen, Toman; Agranovich, Bella; Eckhardt, Lara Elea; Herdt, Martin; Henneberg, Alessa; Panitz, Verena; Hayat, Faisal; Migaud, Marie; Poschet, Gernot; Abramovich, Ifat; Gottlieb, Eyal; Krijgsveld, Jeroen; Ziegler, Mathias; Prentzell, Mirja Tamara; Opitz, Christiane A. 分享 收藏
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A metabolic switch to the pentose-phosphate pathway induces radiation resistance in pancreatic cancer 戊糖-磷酸途径的代谢转换诱导胰腺癌的辐射抗性 Shimoni-Sebag, Ariel; Abramovich, Ifat; Agranovich, Bella; Massri, Rami; Stossel, Chani; Atias, Dikla; Raites-Gurevich, Maria; Yizhak, Keren; Golan, Talia; Gottlieb, Eyal; Lawrence, Yaacov Richard 分享 收藏
Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis 抑制肝草酸盐过量产生可改善代谢功能障碍相关的脂肪性肝炎 Das, Sandeep; Finney, Alexandra C.; Anand, Sumit Kumar; Rohilla, Sumati; Liu, Yuhao; Pandey, Nilesh; Ghrayeb, Alia; Kumar, Dhananjay; Nunez, Kelley; Liu, Zhipeng; Arias, Fabio; Zhao, Ying; Pearson-Gallion, Brenna H.; McKinney, M. Peyton; Richard, Koral S. E.; Gomez-Vidal, Jose A.; Abdullah, Chowdhury S.; Cockerham, Elizabeth D.; Eniafe, Joseph; Yurochko, Andrew D.; Magdy, Tarek; Pattillo, Christopher B.; Kevil, Christopher G.; Razani, Babak; Bhuiyan, Md. Shenuarin; Seeley, Erin H.; Galliano, Gretchen E.; Wei, Bo; Tan, Lin; Mahmud, Iqbal; Surakka, Ida; Garcia-Barrio, Minerva T.; Lorenzi, Philip L.; Gottlieb, Eyal; Salido, Eduardo; Zhang, Jifeng; Orr, A. Wayne; Liu, Wanqing; Diaz-Gavilan, Monica; Chen, Y. Eugene; Dhanesha, Nirav; Thevenot, Paul T.; Cohen, Ari J.; Yurdagul Jr, Arif; Rom, Oren 分享 收藏
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Diet-omics in the Study of Urban and Rural Crohn disease Evolution (SOURCE) cohort Braun, Tzipi; Feng, Rui; Amir, Amnon; Levhar, Nina; Shacham, Hila; Mao, Ren; Hadar, Rotem; Toren, Itamar; Algavi, Yadid; Abu-Saad, Kathleen; Zhuo, Shuoyu; Efroni, Gilat; Malik, Alona; Picard, Orit; Yavzori, Miri; Agranovich, Bella; Liu, Ta-Chiang; Stappenbeck, Thaddeus S.; Denson, Lee; Kalter-Leibovici, Ofra; Gottlieb, Eyal; Borenstein, Elhanan; Elinav, Eran; Chen, Minhu; Ben-Horin, Shomron; Haberman, Yael 分享 收藏
Serine Hydroxymethyltransferase 2 In Hepatocytes Regulates One-carbon Metabolism, Circulating VLDL And Atherosclerosis McKinney, Mary P.; Ghrayeb, Alia; Finney, Alexandra; Anand, Sumit K.; Rohilla, Sumati; Das, Sandeep; Pearson-gallion, Brenna; Tan, Lin; Lorenzi, Philip; Orr, Wayne W.; Yurdagul, Arif; Mor, Inbal; Gottlieb, Eyal; Rom, Oren 分享 收藏
Loss Of Serine Hydroxymethyltransferase 2 In Macrophages Blunts Glutathione And Enhances Ceramide Synthesis To Accelerate Atherosclerosis Rohilla, Sumati; Ghrayeb, Alia; Finney, Alexandra C.; McKinney, M. Peyton; Liu, Yuhao; Nam, Hugh; Tan, Lin; Lorenzi, Philip L.; Mor, Inbal; Orr, A. Wayne; Gottlieb, Eyal; Yurdagul, Arif, Jr.; Rom, Oren 分享 收藏
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Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy 编程铁死亡到细胞凋亡的过渡景观揭示了铁死亡生物标志物和抑制因子用于癌症治疗 Vinik, Yaron; Maimon, Avi; Dubey, Vinay; Raj, Harsha; Abramovitch, Ifat; Malitsky, Sergey; Itkin, Maxim; Ma'ayan, Avi; Westermann, Frank; Gottlieb, Eyal; Ruppin, Eytan; Lev, Sima 分享 收藏
Failure to mate enhances investment in behaviors that may promote mating reward and impairs the ability to cope with stressors via a subpopulation of Neuropeptide F receptor neurons Ryvkin, Julia; Omesi, Liora; Kim, Yong-Kyu; Levi, Mali; Pozeilov, Hadar; Barak-Buchris, Lital; Agranovich, Bella; Abramovich, Ifat; Gottlieb, Eyal; Jacob, Avi; Naessel, Dick R.; Heberlein, Ulrike; Shohat-Ophir, Galit 分享 收藏
Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD Ghrayeb, Alia; Finney, Alexandra C.; Agranovich, Bella; Peled, Daniel; Anand, Sumit Kumar; Mckinney, M. Peyton; Sarji, Mahasen; Yang, Dongshan; Weissman, Natan; Drucker, Shani; Fernandes, Sara Isabel; Fernandez-Garcia, Jonatan; Mahan, Kyle; Abassi, Zaid; Tan, Lin; Lorenzi, Philip L.; Traylor, James; Zhang, Jifeng; Abramovich, Ifat; Chen, Y. Eugene; Rom, Oren; Mor, Inbal; Gottlieb, Eyal 分享 收藏
Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells Linder, Samantha J.; Bernasocchi, Tiziano; Martinez-Pastor, Barbara; Sullivan, Kelly D.; Galbraith, Matthew D.; Lewis, Caroline A.; Ferrer, Christina M.; Boon, Ruben; Silveira, Giorgia G.; Cho, Hyo Min; Vidoudez, Charles; Shroff, Stuti; Oliveira-Costa, Joao P.; Ross, Kenneth N.; Massri, Rami; Matoba, Yusuke; Kim, Eugene; Rueda, Bo R.; Stott, Shannon L.; Gottlieb, Eyal; Espinosa, Joaquin M.; Mostoslavsky, Raul 分享 收藏
Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction Radzishevsky, Inna; Odeh, Maali; Bodner, Oded; Zubedat, Salman; Shaulov, Lihi; Litvak, Maxim; Esaki, Kayoko; Yoshikawa, Takeo; Agranovich, Bella; Li, Wen-Hong; Radzishevsky, Alex; Gottlieb, Eyal; Avital, Avi; Wolosker, Herman 分享 收藏
Regulation of nucleo-cytosolic 26S proteasome translocation by aromatic amino acids via mTOR is essential for cell survival under stress 通过mTOR调节芳香族氨基酸对核-胞质26s蛋白酶体易位的调节对于细胞在压力下的生存至关重要 Livneh, Ido; Cohen-Kaplan, Victoria; Fabre, Bertrand; Abramovitch, Ifat; Chen, Lulu; Nataraj, Nishanth Belugali; Lazar, Ikrame; Ziv, Tamar; Yarden, Yosef; Zohar, Yaniv; Gottlieb, Eyal; Ciechanover, Aaron 分享 收藏
Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells Rattigan, Kevin M.; Brabcova, Zuzana; Sarnello, Daniele; Zarou, Martha M.; Roy, Kiron; Kwan, Ryan; de Beauchamp, Lucie; Dawson, Amy; Ianniciello, Angela; Khalaf, Ahmed; Kalkman, Eric R.; Scott, Mary T.; Dunn, Karen; Sumpton, David; Michie, Alison M.; Copland, Mhairi; Tardito, Saverio; Gottlieb, Eyal; Helgason, G. Vignir 分享 收藏
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