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Z

Zachary T. Schug

Wistar Institute
H指数:28
被引数:7,259

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Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer

乙酸盐通过增强T细胞效应子功能和增强乳腺癌的抗肿瘤免疫力而充当代谢免疫调节剂

NATURE CANCER
IF28.5
2023-09-1825
OA
Miller, Katelyn D.; O'Connor, Seamus; Pniewski, Katherine A.; Kannan, Toshitha; Acosta, Reyes; Mirji, Gauri; Papp, Sara; Hulse, Michael; Mukha, Dzmitry; Hlavaty, Sabina I.; Salcido, Kelsey N.; Bertolazzi, Fabrizio; Srikanth, Yellamelli V. V.; Zhao, Steven; Wellen, Kathryn E.; Shinde, Rahul S.; Claiborne, Daniel T.; Kossenkov, Andrew; Salvino, Joseph M.; Schug, Zachary T.
Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma
NATURE CANCER
IF28.5
2021-01-1162
OAAI
Wu, Shuai; Fukumoto, Takeshi; Lin, Jianhuang; Nacarelli, Timothy; Wang, Yemin; Ong, Dionzie; Liu, Heng; Fatkhutdinov, Nail; Zundell, Joseph A.; Karakashev, Sergey; Zhou, Wei; Schwartz, Lauren E.; Tang, Hsin-Yao; Drapkin, Ronny; Liu, Qin; Huntsman, David G.; Kossenkov, Andrew V.; Speicher, David W.; Schug, Zachary T.; Van Dang, Chi; Zhang, Rugang
Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2

老年成纤维细胞脂质代谢的变化通过脂肪酸转运蛋白FATP2诱导年龄依赖性黑色素瘤细胞对靶向治疗的抗性

CANCER DISCOVERY
IF33.3
2020-06-0490
OAAI
Alicea, Gretchen M.; Rebecca, Vito W.; Goldman, Aaron R.; Fane, Mitchell E.; Douglass, Stephen M.; Behera, Reeti; Webster, Marie R.; Kugel, Curtis H., III; Ecker, Brett L.; Caino, M. Cecilia; Kossenkov, Andrew, V; Tang, Hsin-Yao; Frederick, Dennie T.; Flaherty, Keith T.; Xu, Xiaowei; Liu, Qin; Gabrilovich, Dmitry, I; Herlyn, Meenhard; Blair, Ian A.; Schug, Zachary T.; Speicher, David W.; Weeraratna, Ashani T.
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate
Nature
IF48.5
2020-03-180
PREAI
Steven Zhao; Cholsoon Jang; Joyce Liu; Kahealani Uehara; Michael Gilbert; Luke Izzo; Xianfeng Zeng; Sophie Trefely; Sully Fernandez; Alessandro Carrer; Katelyn D. Miller; Zachary T. Schug; Nathaniel W. Snyder; Terence P. Gade; Paul M. Titchenell; Joshua D. Rabinowitz; Kathryn E. Wellen
MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer
BRITISH JOURNAL OF CANCER
IF6.8
2020-01-1667
OAAI
Casciano, Jessica C.; Perry, Caroline; Cohen-Nowak, Adam J.; Miller, Katelyn D.; Vande Voorde, Johan; Zhang, Qifeng; Chalmers, Susan; Sandison, Mairi E.; Liu, Qin; Hedley, Ann; McBryan, Tony; Tang, Hsin-Yao; Gorman, Nicole; Beer, Thomas; Speicher, David W.; Adams, Peter D.; Liu, Xuefeng; Schlegel, Richard; McCarron, John G.; Wakelam, Michael J. O.; Gottlieb, Eyal; Kossenkov, Andrew V.; Schug, Zachary T.
Polyunsaturated Fatty Acids from Astrocytes Activate PPARγ Signaling in Cancer Cells to Promote Brain Metastasis

星形胶质细胞多不饱和脂肪酸激活癌细胞ppar γ 信号促进脑转移

CANCER DISCOVERY
IF33.3
2019-12-02105
OAAI
Zou, Yongkang; Watters, Andrea; Cheng, Nan; Perry, Caroline E.; Xu, Ke; Alicea, Gretchen M.; Parris, Joshua L. D.; Baraban, Ezra; Ray, Pulak; Nayak, Anupma; Xu, Xiaowei; Herlyn, Meenhard; Murphy, Maureen E.; Weeraratna, Ashani T.; Schug, Zachary T.; Chen, Qing

研究方向

暂未获取到该数据
E
Eyal Gottlieb
H 指数:77论文数:295被引数:4.4万
D
David W. Speicher
H 指数:86论文数:614被引数:2.8万
A
Andrew V. Kossenkov
H 指数:72论文数:804被引数:1.8万
J
Johan Vande Voorde
H 指数:21论文数:58被引数:2,484
H
Hsin‐Yao Tang
H 指数:52论文数:417被引数:9,948
S
Suresh K. Joseph
H 指数:54论文数:142被引数:1.2万
Q
Qin Liu
H 指数:72论文数:976被引数:2.2万
K
Kathryn E. Wellen
H 指数:52论文数:177被引数:2.3万
K
Katelyn D. Miller
H 指数:10论文数:30被引数:1,095
A
Andrew E. Aplin
H 指数:55论文数:508被引数:1.0万