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D

David Loughrey

university system of georgia
H指数:23
被引数:3,083

个人简介

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荣誉奖项

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Nanoparticle delivery of a prodrug-activating bacterial enzyme leads to anti-tumor responses

纳米粒递送一种前药激活的细菌酶可诱导抗肿瘤反应

NATURE COMMUNICATIONS
IF15.7
2025-04-120
OA
Huayamares, Sebastian G.; Lian, Liming; Rab, Regina; Hou, Yuning; Radmand, Afsane; Kim, Hyejin; Zenhausern, Ryan; Achyut, Bhagelu R.; Ross, Melissa Gilbert; Lokugamage, Melissa P.; Loughrey, David; Peck, Hannah E.; Echeverri, Elisa Schrader; Sanchez, Alejandro J. Da Silva; Shajii, Aram; Li, Andrea; Tiegreen, Karen E.; Santangelo, Philip J.; Sorscher, Eric J.; Dahlman, James E.
Lipid nanoparticle-mediated mRNA delivery to CD34+ cells in rhesus monkeys

脂质纳米颗粒介导的恒河猴CD34细胞的mRNA传递

NATURE BIOTECHNOLOGY
IF41.7
2024-11-220
PRE
Kim, Hyejin; Zenhausern, Ryan; Gentry, Kara; Lian, Liming; Huayamares, Sebastian G.; Radmand, Afsane; Loughrey, David; Podilapu, Ananda R.; Hatit, Marine Z. C.; Ni, Huanzhen; Li, Andrea; Shajii, Aram; Peck, Hannah E.; Han, Keyi; Hua, Xuanwen; Jia, Shu; Martinez, Michele; Lee, Charles; Santangelo, Philip J.; Tarantal, Alice; Dahlman, James E.
Lipid nanoparticles deliver mRNA to the blood-brain barrier

脂质纳米颗粒将mRNA递送至血脑屏障

NANO RESEARCH
IF9
2024-08-010
PRE
Kuzminich, Yanina; Shakked, Avraham; Calkins, Randi; Rudden, Sebastian; Jones, Camille; Doan, Jessie; Jang, Bora; Echeverri, Elisa Schrader; Zenhausern, Ryan; Lian, Liming; Loughrey, David; Peck, Hannah E.; Wiese, Rachelle; Koveal, Dorothy; Santangelo, Philip J.; Dahlman, James E.
Cationic cholesterol- dependent LNP delivery to lung stem cells, the liver, and heart
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-03-049
OAAI
Radmand, Afsane; Kim, Hyejin; Beyersdorf, Jared; Dobrowolski, Curtis N.; Zenhausern, Ryan; Paunovska, Kalina; Huayamares, Sebastian G.; Hua, Xuanwen; Han, Keyi; Loughrey, David; Hatit, Marine Z. C.; Del Cid, Ada; Ni, Huanzhen; Shajii, Aram; Li, Andrea; Muralidharan, Abinaya; Peck, Hannah E.; Tiegreen, Karen E.; Jia, Shu; Santangelo, Philip J.; Dahlman, James E.
High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo
JOURNAL OF CONTROLLED RELEASE
IF11.5
2023-05-0130
OAAI
Huayamares, Sebastian G.; Lokugamage, Melissa P.; Rab, Regina; Sanchez, Alejandro J. Da Silva; Kim, Hyejin; Radmand, Afsane; Loughrey, David; Lian, Liming; Hou, Yuning; Achyut, Bhagelu R.; Ehrhardt, Annette; Hong, Jeong S.; Sago, Cory D.; Paunovska, Kalina; Echeverri, Elisa Schrader; Vanover, Daryll; Santangelo, Philip J.; Sorscher, Eric J.; Dahlman, James E.
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery

纳米粒子立体化学依赖性内吞加工改善体内mRNA递送

NATURE CHEMISTRY
IF20.2
2023-03-0231
PRE
Hatit, Marine Z. C.; Dobrowolski, Curtis N.; Lokugamage, Melissa P.; Loughrey, David; Ni, Huanzhen; Zurla, Chiara; Sanchez, Alejandro Da Silva J.; Radmand, Afsane; Huayamares, Sebastian G.; Zenhausern, Ryan; Paunovska, Kalina; Peck, Hannah E.; Kim, Jinwhan; Sato, Manaka; Feldman, Jacob I.; Rivera, Michael-Alexander; Cristian, Ana; Kim, YongTae; Santangelo, Philip J.; Dahlman, James E.
The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo

肺靶向脂质纳米粒的体内转录反应

NANO LETTERS
IF9.1
2023-01-2632
OAAI
Radmand, Afsane; Lokugamage, Melissa P.; Kim, Hyejin; Dobrowolski, Curtis; Zenhausern, Ryan; Loughrey, David; Huayamares, Sebastian G.; Hatit, Marine Z. C.; Ni, Huanzhen; Del Cid, Ada; Sanchez, Alejandro J. Da Silva; Paunovska, Kalina; Echeverri, Elisa Schrader; Shajii, Aram; Peck, Hannah; Santangelo, Philip J.; Dahlman, James E.
The Extent to Which Lipid Nanoparticles Require Apolipoprotein E and Low-Density Lipoprotein Receptor for Delivery Changes with Ionizable Lipid Structure

脂质纳米颗粒需要载脂蛋白E和低密度脂蛋白受体递送的程度随可电离脂质结构的变化而变化

NANO LETTERS
IF9.1
2022-12-1524
PRE
Paunovska, Kalina; Da Silva Sanchez, Alejandro J.; Lokugamage, Melissa P.; Loughrey, David; Echeverri, Elisa Schrader; Cristian, Ana; Hatit, Marine Z. C.; Santangelo, Philip J.; Zhao, Kun; Dahlman, James E.
Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver
NATURE BIOMEDICAL ENGINEERING
IF26.6
2022-02-2145
PRE
Sago, Cory D.; Lokugamage, Melissa P.; Loughrey, David; Lindsay, Kevin E.; Hincapie, Robert; Krupczak, Brandon R.; Kalathoor, Sujay; Sato, Manaka; Echeverri, Elisa Schrader; Fitzgerald, Jordan P.; Gan, Zubao; Gamboa, Lena; Paunovska, Kalina; Sanhueza, Carlos A.; Hatit, Marine Z. C.; Finn, M. G.; Santangelo, Philip J.; Dahlman, James E.

研究方向

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J
James E. Dahlman
H 指数:48论文数:123被引数:1.3万
K
Kalina Paunovska
H 指数:21论文数:30被引数:3,269
P
Philip J. Santangelo
H 指数:49论文数:182被引数:7,573
M
Marine Z. C. Hatit
H 指数:19论文数:26被引数:1,657
E
Elisa Schrader Echeverri
H 指数:12论文数:28被引数:1,064
S
Sebastian G. Huayamares
H 指数:12论文数:22被引数:648
A
Alejandro J. Da Silva Sanchez
H 指数:9论文数:24被引数:735
M
Melissa P. Lokugamage
H 指数:21论文数:29被引数:2,645
R
Ryan Zenhausern
H 指数:10论文数:20被引数:452
H
Hyejin Kim
H 指数:34论文数:154被引数:3,925