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M

Maxwell R. Lloyd

Beth Israel Deaconess Medical Center
H指数:15
被引数:2,434

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Safety and antitumour activity of ipatasertib combined with endocrine therapy and a CDK4/6 inhibitor in HR+/HER2– metastatic breast cancer (TAKTIC): a single-centre, open-label, phase 1b trial

伊帕西替布联合内分泌疗法和CDK4/6抑制剂在HR+/HER2–转移性乳腺癌中的安全性和抗肿瘤活性（TAKTIC）：一项单中心、开放标签、1b期临床试验

The Lancet Oncology
IF0
2026-04-270
PRE
Seth A Wander; Maxwell R Lloyd; Jennifer C Keenan; Elizabeth C Scott; Andrzej Niemierko; Laura M Spring; Geoffrey G Fell; Jennifer Shin; Steven J Isakoff; Beverly Moy; Lianne Ryan; Sarah Padden; Elizabeth Fisher; Amber Newton; Karleen R Habin; Elene T Viscosi-Spieler; Lauren Scarpetti; Andreas Varkaris; Leif W Ellisen; Taronish Dubash
A bedside-to-bench translational analysis of NF1 alterations and CDK4/6 inhibitor resistance in hormone receptor-positive metastatic breast cancer

NF1基因改变与CDK4/6抑制剂耐药在激素受体阳性转移性乳腺癌中的从临床到基础研究的转化分析

eBioMedicine
IF10.8
2025-06-270
PRE
Maxwell R. Lloyd; Rosario Chica-Parrado; Caroline M. Weipert; Todd C. Knepper; Emily L. Podany; Fabiana Napolitano; Dan Ye; Chang-Ching Lin; Yasuaki Uemoto; Jiemin Liao; Claire Wegrzyn; Christine M. Walko; Lianne Y. Ryan; Jennifer C. Keenan; Arielle J. Medford; Shiyuan A. Liu; Gerburg M. Wulf; Katherine K. Clifton; Cynthia X. Ma; Hyo S. Han; Nicole Zhang; Leif W. Ellisen; Aditya Bardia; Carlos L. Arteaga; Ariella B. Hanker; Seth A. Wander
A bedside-to-bench translational analysis demonstrates that NF1 alterations promote CDK4/6 inhibitor (CDK4/6i) resistance in hormone receptor-positive (HR plus ) metastatic breast cancer (MBC)
CANCER RESEARCH
IF16.6
2024-05-020
PRE
Lloyd, Maxwell; Chica-Parrado, M. Rosario; Knepper, Todd; Lin, Chang-Ching; Podany, Emily; Walko, Christine; Napolitano, Fabiana; Weipert, Caroline; Liao, Jiemin; Medford, Arielle; Ryan, Lianne; Keenan, Jennifer; Zhang, Nicole; Liu, Shiyuan; Wulf, Gerburg; Clifton, Katherine; Ma, Cynthia; Han, Hyo; Ellisen, Leif; Bardia, Aditya; Arteaga, Carlos; Hanker, Ariella; Wander, Seth
Characterization and proposed therapeutic exploitation of fusion RNAs in metastatic breast cancers
CANCER RESEARCH
IF16.6
2024-05-021
PRE
Priedigkeit, Nolan; Lebron-Torres, Alines; Liao, Janny; Alberge, Jean-Baptiste; Morganti, Stefania; Weiss, Jakob; Zanudo, Jorge Gomez Tejeda; Grinshpun, Albert; Hughes, Melissa; Helvie, Karla; Sendrick, Kerry; Nguyen, Kyleen; Strauss, Sarah; Files, Janet; Lloyd, Maxwell; Wagle, Nikhil; Stewart, Chip; Winer, Eric; Johnson, Bruce; Li, Yvonne; Jeselsohn, Rinath; Tolaney, Sara; Abravanel, Daniel; Lin, Nancy; Parsons, Heather; Getz, Gad; Oesterreich, Steffi; Lee, Adrian; Golub, Todd
Association between co-existing genomic alterations and abemaciclib benefit in patients with metastatic hormone receptor-positive breast cancer with ESR1 mutations following disease progression on prior endocrine therapy plus palbociclib or ribociclib
CANCER RESEARCH
IF16.6
2022-02-151
PRE
Brett, Jamie O.; Dubash, Taronish D.; Niemierko, Andrzej; Mariotti, Veronica; Kim, Leslie S. L.; Xi, Jing; Pandey, Apurva; Dunne, Siobhan; Nasrazadani, Azadeh; Lloyd, Maxwell R.; Spring, Laura M.; Micalizzi, Douglas; Onozato, Maristela; Che, Dante; Brufsky, Adam; Kalinsky, Kevin M.; Ma, Cynthia X.; O'Shaughnessy, Joyce; Han, Hyo S.; Iafrate, A. John; Maheswaran, Shyamala; Haber, Daniel A.; Bardia, Aditya; Wander, Seth A.
Genomic Characterization of de novo Metastatic Breast Cancer
CLINICAL CANCER RESEARCH
IF10.2
2021-02-1526
OAAI
Garrido-Castro, Ana C.; Spurr, Liam F.; Hughes, Melissa E.; Li, Yvonne Y.; Cherniack, Andrew D.; Kumari, Priti; Lloyd, Maxwell R.; Bychkovsky, Brittany; Barroso-Sousa, Romualdo; Di Lascio, Simona; Jain, Esha; Files, Janet; Mohammed-Abreu, Ayesha; Krevalin, Max; MacKichan, Colin; Barry, William T.; Guo, Hao; Xia, Daniel; Cerami, Ethan; Rollins, Barrett J.; MacConaill, Laura E.; Lindeman, Neal, I; Krop, Ian E.; Johnson, Bruce E.; Wagle, Nikhil; Winer, Eric P.; Dillon, Deborah A.; Lin, Nancy U.
The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor-Positive Metastatic Breast Cancer

激素受体阳性转移性乳腺癌患者对细胞周期蛋白依赖性激酶4/6抑制剂的内在和获得性耐药的基因组景观

CANCER DISCOVERY
IF33.3
2020-08-03210
OAAI
Wander, Seth A.; Cohent, Ofir; Gong, Xueqian; Johnson, Gabriela N.; Buendia-Buendia, Jorge E.; Lloyd, Maxwell R.; Kim, Dewey; Luo, Flora; Mao, Pingping; Helvie, Karla; Kowalski, Kalley J.; Nayar, Utthara; Waks, Adrienne G.; Parsons, Stephen H.; Martinez, Ricardo; Litchfield, Lacey M.; Ye, Xiang S.; Yu, Chunping; Jansen, Valerie M.; Stille, John R.; Smith, Patricia S.; Oakley, Gerard J.; Chu, Quincy S.; Batist, Gerald; Hughes, Melissa E.; Kremer, Jill D.; Garraway, Levi A.; Winer, Erik P.; Tolaney, Sara M.; Lin, Nancy U.; Buchanan, Sean G.; Wagle, Nikhil
Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer

BRCA1/2突变转移性乳腺癌对PARP抑制剂或铂类化疗耐药的逆转和非逆转机制

ANNALS OF ONCOLOGY
IF65.4
2020-05-01116
OAAI
Waks, A. G.; Coheny, O.; Kochupurakkal, B.; Kim, D.; Dunn, C. E.; Buendia, J. Buendia; Wander, S.; Helvie, K.; Lloyd, M. R.; Marini, L.; Hughes, M. E.; Freeman, S. S.; Ivy, S. P.; Geradts, J.; Isakoff, S.; LoRusso, P.; Adalsteinsson, V. A.; Tolaney, S. M.; Matulonis, U.; Krop, I. E.; D'Andrea, A. D.; Winer, E. P.; Lin, N. U.; Shapiro, G. I.; Wagle, N.
The genomic landscape of intrinsic and acquired resistance to cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) in patients with hormone receptor-positive (HR+)/HER2-metastatic breast cancer (MBC)
CANCER RESEARCH
IF16.6
2020-02-151
PRE
Wander, Seth A.; Cohen, Ofir; Gong, Xueqian; Johnson, Gabriela N.; Buendia-Buendia, Jorge; Lloyd, Maxwell; Kim, Dewey; Luo, Flora; Mao, Pingping; Helvie, Karla; Kowalski, Kailey; Nayar, Utthara; Parsons, Stephen; Martinez, Ricardo; Litchfield, Lacey; Ye, Xiang; Yu, Chun Ping; Jansen, Valerie; Garraway, Levi A.; Winer, Eric P.; Tolaney, Sara M.; Lin, Nancy U.; Buchanan, Sean; Wagle, Nikhil
Evolutionary analysis of 462 serial metastatic biopsies from 208 patients with estrogen receptor-positive (ER plus ) metastatic breast cancer (MBC) using whole exome sequencing (WES)
CANCER RESEARCH
IF16.6
2019-02-151
PRE
Cohen, O.; Buendia-Buendia, J.; Wander, S.; Nayar, U.; Mao, P.; Waks, A.; Kim, D.; Freeman, S.; Adalsteinsson, V.; Helvie, K.; Livitz, D.; Rosebrock, D.; Leshchiner, I.; Dellostritto, L.; Garrido-Castro, A.; Jain, E.; Periyasamy, S.; Mackichan, C.; Lloyd, M.; Marini, L.; Krop, I.; Garraway, L.; Getz, G.; Winer, E.; Lin, N.; Wagle, N.
High concordance of whole-exome sequencing of cell-free DNA and matched biopsies enables genomic discovery in metastatic cancer
CANCER RESEARCH
IF16.6
2016-07-150
PRE
Adalsteinsson, Viktor A.; Ha, Gavin; Freeman, Sam; Choudhury, Atish D.; Stover, Daniel G.; Parsons, Heather A.; Gydush, Gregory; Reed, Sarah; Loginov, Denis; Livitz, Dimitri; Rosebrock, Daniel; Leshchiner, Ignat; Cohen, Ofir; Oh, Coyin; Kim, Jaegil; Stewart, Chip; Rosenberg, Mara; Ding, Huiming; Lloyd, Maxwell R.; Mahmud, Sairah; Helvie, Karla E.; Merrill, Margaret S.; Santiago, Rebecca A.; O'Connor, Edward P.; Jeong, Seong H.; Kramkowski, Joseph F.; Lohr, Jens G.; Polacek, Laura; Oliver, Nelly; Marini, Lori; Francis, Joshua; Harshman, Lauren C.; Van Allen, Eliezer M.; Winer, Eric P.; Lin, Nancy U.; Nakabayashi, Mari; Taplin, Mary-Ellen; Garraway, Levi A.; Golub, Todd R.; Boehm, Jesse S.; Wagle, Nikhil; Getz, Gad; Meyerson, Matthew; Love, Christopher J.

研究方向

暂未获取到该数据
S
Seth A. Wander
H 指数:35论文数:342被引数:5,325
A
Aditya Bardia
H 指数:86论文数:1,147被引数:3.8万
N
Nikhil Wagle
H 指数:60论文数:598被引数:2.2万
E
Eric P. Winer
H 指数:170论文数:1,624被引数:12.9万
N
Nancy U. Lin
H 指数:95论文数:1,073被引数:4.2万
K
Karla Helvie
H 指数:15论文数:114被引数:3,550
S
Sara M. Tolaney
H 指数:83论文数:1,341被引数:3.5万
O
Ofir Cohen
H 指数:42论文数:264被引数:1.4万
L
Leif W. Ellisen
H 指数:66论文数:464被引数:2.4万
L
Levi A. Garraway
H 指数:147论文数:1,018被引数:14.8万