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P

Peter M.K. Westcott

massachusetts institute of technology
H指数:20
被引数:2,691

个人简介

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教育背景

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工作经历

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荣誉奖项

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Compartment-specific PPARδ activity controls the outcome of cancer–immune cell competition and immunotherapy efficacy

亚细胞区室特异性的PPARδ活性调控癌症-免疫细胞竞争的结果及免疫治疗效果

Nature Immunology
IF27.6
2026-10-140
OAAI
Paul Bunk; Ilgin Ergin; Timothy Maher; Vyom Shah; Julia R. Bonney; Lokesh B. S. S. Kumar; Charlie Chung; Nils Wellhausen; Philip Moresco; Sarah Shao; Jill Habel; Vinay Mandati; Rachel Rubino; David E. Rivadeneira; John E. Wilkinson; Laura Herrero; Peter M. K. Westcott; Samuel E. Weinberg; Saar I. Gill; Nathalie Y. R. Agar; Semir Beyaz
The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1
NATURE CANCER
IF28.5
2024-10-111
OAAI
Romero, Rodrigo; Chu, Tinyi; Robles, Tania J. Gonzalez; Smith, Perianne; Xie, Yubin; Kaur, Harmanpreet; Yoder, Sara; Zhao, Huiyong; Mao, Chenyi; Kang, Wenfei; Pulina, Maria V.; Lawrence, Kayla E.; Gopalan, Anuradha; Zaidi, Samir; Yoo, Kwangmin; Choi, Jungmin; Fan, Ning; Gerstner, Olivia; Karthaus, Wouter R.; Destanchina, Elisa; Ruggles, Kelly V.; Westcott, Peter M. K.; Chaligne, Ronan; Pe'er, Dana; Sawyers, Charles L.
Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity

错配修复缺陷不足以引起肿瘤免疫原性

NATURE GENETICS
IF31.8
2023-09-1446
OAAI
Westcott, Peter M. K.; Muyas, Francesc; Hauck, Haley; Smith, Olivia C.; Sacks, Nathan J.; Ely, Zackery A.; Jaeger, Alex M.; Rideout, William M., III; Zhang, Daniel; Bhutkar, Arjun; Beytagh, Mary C.; Canner, David A.; Jaramillo, Grissel C.; Bronson, Roderick T.; Naranjo, Santiago; Jin, Abbey; Patten, J. J.; Cruz, Amanda M.; Shanahan, Sean-Luc; Cortes-Ciriano, Isidro; Jacks, Tyler
A prime editor mouse to model a broad spectrum of somatic mutations in vivo

prime editor小鼠在体内建立广泛的体细胞突变模型

NATURE BIOTECHNOLOGY
IF41.7
2023-05-1120
OA
Ely, Zackery A.; Mathey-Andrews, Nicolas; Naranjo, Santiago; Gould, Samuel I.; Mercer, Kim L.; Newby, Gregory A.; Cabana, Christina M.; Rideout III, William M.; Jaramillo, Grissel Cervantes; Khirallah, Jennifer M.; Holland, Katie; Randolph, Peyton B.; Freed-Pastor, William A.; Davis, Jessie R.; Kulstad, Zachary; Westcott, Peter M. K.; Lin, Lin; Anzalone, Andrew V.; Horton, Brendan L.; Pattada, Nimisha B.; Shanahan, Sean-Luc; Ye, Zhongfeng; Spranger, Stefani; Xu, Qiaobing; Sanchez-Rivera, Francisco J.; Liu, David R.; Jacks, Tyler
Smarca4 Inactivation Promotes Lineage- Specific Transformation and Early Metastatic Features in the Lung
CANCER DISCOVERY
IF33.3
2022-02-0935
OA
Concepcion, Carla P.; Ma, Sai; LaFave, Lindsay M.; Bhutkar, Arjun; Liu, Manyuan; DeAngelo, Lydia P.; Kim, Jonathan Y.; Del Priore, Isabella; Schoenfeld, Adam J.; Miller, Manon; Kartha, Vinay K.; Westcott, Peter M. K.; Sanchez-Rivera, Francisco J.; Meli, Kevin; Gupta, Manav; Bronson, Roderick T.; Riely, Gregory J.; Rekhtman, Natasha; Rudin, Charles M.; Kim, Carla F.; Regev, Aviv; Buenrostro, Jason D.; Jacks, Tyler
Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

常规I型树突状细胞在肿瘤引流淋巴结中维持增殖性肿瘤抗原特异性TCF-1 CD8 T细胞库

IMMUNITY
IF26.3
2021-10-01154
OA
Schenkel, Jason M.; Herbst, Rebecca H.; Canner, David; Li, Amy; Hillman, Michelle; Shanahan, Sean-Luc; Gibbons, Grace; Smith, Olivia C.; Kim, Jonathan Y.; Westcott, Peter; Hwang, William L.; Freed-Pastor, William A.; Eng, George; Cuoco, Michael S.; Rogers, Patricia; Park, Jin K.; Burger, Megan L.; Rozenblatt-Rosen, Orit; Cong, Le; Pauken, Kristen E.; Regev, Aviv; Jacks, Tyler
Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1 (vol 1, pg 589, 2020)

Keap1突变使肺腺癌依赖于Slc33a1 (第1卷，589页，2020)

NATURE CANCER
IF28.5
2020-08-211
OAAI
Romero, Rodrigo; Sanchez-Rivera, Francisco J.; Westcott, Peter M. K.; Mercer, Kim L.; Bhutkar, Arjun; Muir, Alexander; Gonzalez Robles, Tania J.; Rodriguez, Swanny Lamboy; Liao, Laura Z.; Ng, Sheng Rong; Li, Leanne; Colon, Caterina I.; Naranjo, Santiago; Beytagh, Mary Clare; Lewis, Caroline A.; Hsu, Peggy P.; Bronson, Roderick T.; Vander Heiden, Matthew G.; Jacks, Tyler
Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1
NATURE CANCER
IF28.5
2020-06-0844
OAAI
Romero, Rodrigo; Sanchez-Rivera, Francisco J.; Westcott, Peter M. K.; Mercer, Kim L.; Bhutkar, Arjun; Muir, Alexander; Robles, Tania J. Gonzalez; Rodriguez, Swanny Lamboy; Liao, Laura Z.; Ng, Sheng Rong; Li, Leanne; Colon, Caterina I.; Naranjo, Santiago; Beytagh, Mary Clare; Lewis, Caroline A.; Hsu, Peggy P.; Bronson, Roderick T.; Vander Heiden, Matthew G.; Jacks, Tyler
Identification of DHODH as a therapeutic target in small cell lung cancer
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2019-11-06102
OAAI
Li, Leanne; Ng, Sheng Rong; Colon, Caterina I.; Drapkin, Benjamin J.; Hsu, Peggy P.; Li, Zhaoqi; Nabel, Christopher S.; Lewis, Caroline A.; Romero, Rodrigo; Mercer, Kim L.; Bhutkar, Arjun; Phat, Sarah; Myers, David T.; Muzumdar, Mandar Deepak; Westcott, Peter M. K.; Beytagh, Mary Clare; Farago, Anna F.; Vander Heiden, Matthew G.; Dyson, Nicholas J.; Jacks, Tyler

研究方向

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T
Tyler Jacks
H 指数:158论文数:823被引数:12.6万
M
Mary C. Beytagh
H 指数:8论文数:71被引数:769
O
Olivia Smith
H 指数:11论文数:51被引数:1,478
A
Arjun Bhutkar
H 指数:43论文数:237被引数:1.0万
K
Kim L. Mercer
H 指数:15论文数:23被引数:6,990
F
Francisco J. Sánchez‐Rivera
H 指数:36论文数:188被引数:7,102
R
Rodrigo Romero
H 指数:9论文数:25被引数:2,087
A
Allan Balmain
H 指数:73论文数:332被引数:2.4万
M
Minh D. To
H 指数:21论文数:60被引数:1,813
R
Roderick T. Bronson
H 指数:164论文数:1,099被引数:10.9万