Ronald Wetzel - Publications, H-index & Citations

Ronald Wetzel

University of Pittsburgh

73H指数

219论文数

1.9W被引数

收录论文 55

发表时间

Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington's disease

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2021-04-14

OAAI

Zhou, Ya; Peskett, Thomas R.; Landles, Christian; Warner, John B.; Sathasivam, Kirupa; Smith, Edward J.; Chen, Shu; Wetzel, Ronald; Lashuel, Hilal A.; Bates, Gillian P.; Saibil, Helen R.

Exploding the Repeat Length Paradigm while Exploring Amyloid Toxicity in Huntington's Disease

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2020-09-25

PREAI

Wetzel, Ronald

Mutational analysis implicates the amyloid fibril as the toxic entity in Huntington's disease

NEUROBIOLOGY OF DISEASE

IF5.6

2018-12-01

OAAI

Drombosky, Kenneth W.; Rode, Sascha; Kodali, Ravi; Jacob, Tija C.; Palladino, Michael J.; Wetzel, Ronald

RAD52 is required for RNA-templated recombination repair in post-mitotic neurons

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-01-01

OAAI

Welty, Starr; Teng, Yaqun; Liang, Zhuobin; Zhao, Weixing; Sanders, Laurie H.; Greenamyre, J. Timothy; Rubio, Maria Eulalia; Thathiah, Amantha; Kodali, Ravindra; Wetzel, Ronald; Levine, Arthur S.; Lan, Li

Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core

NATURE COMMUNICATIONS

IF15.7

2017-05-24

OAAI

Lin, Hsiang-Kai; Boatz, Jennifer C.; Krabbendam, Inge E.; Kodali, Ravindra; Hou, Zhipeng; Wetzel, Ronald; Dolga, Amalia M.; Poirier, Michelle A.; van der Wel, Patrick C. A.

Rapid α-oligomer formation mediated by the Aβ C terminus initiates an amyloid assembly pathway

NATURE COMMUNICATIONS

IF15.7

2016-08-22

OAAI

Misra, Pinaki; Kodali, Ravindra; Saketh, Chemuru W.; Kar, Karunakar; Wetzel, Ronald

Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-02-01

137

OAAI

Hoop, Cody L.; Lin, Hsiang-Kai; Kar, Karunakar; Magyarfalvi, Gabor; Lamley, Jonathan M.; Boatz, Jennifer C.; Mandal, Abhishek; Lewandowski, Jozef R.; Wetzel, Ronald; van der Wel, Patrick C. A.

Huntington disease 亨廷顿病

NATURE REVIEWS DISEASE PRIMERS

IF60.6

2015-04-23

1.1K

PREAI

Bates, Gillian P.; Dorsey, Ray; Gusella, James F.; Hayden, Michael R.; Kay, Chris; Leavitt, Blair R.; Nance, Martha; Ross, Christopher A.; Scahill, Rachael I.; Wetzel, Ronald; Wild, Edward J.; Tabrizi, Sarah J.

Huntingtin N-Terminal Fragment Fibrils have a Rigid Amyloid Core Flanked by Non-Amyloid Domains with Increased Dynamics

BIOPHYSICAL JOURNAL

IF3.1

2015-01-01

OAAI

Hoop, Cody L.; Lin, Hsiang-Kai; Kar, Karunakar; Wetzel, Ronald; van der Wel, Patrick C. A.

Biophysical Underpinnings of the Repeat Length Dependence of Polyglutamine Amyloid Formation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-04-01

OAAI

Landrum, Elizabeth; Wetzel, Ronald

Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen

NATURE COMMUNICATIONS

IF15.7

2014-04-01

101

OAAI

Usmani, Shariq M.; Zirafi, Onofrio; Mueller, Janis A.; Sandi-Monroy, Nathallie L.; Yadav, Jay K.; Meier, Christoph; Weil, Tanja; Roan, Nadia R.; Greene, Warner C.; Walther, Paul; Nilsson, K. Peter R.; Hammarstroem, Per; Wetzel, Ronald; Pilcher, Christopher D.; Gagsteiger, Friedrich; Faendrich, Marcus; Kirchhoff, Frank; Muench, Jan

Improved Chemical Synthesis of Hydrophobic Aβ Peptides Using Addition of C-Terminal Lysines Later Removed by Carboxypeptidase B

BIOPOLYMERS

IF3.2

2014-03-21