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G

Gillian P. Bates

university college london
H指数:90
被引数:4.2万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Cas9 nickase–mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington’s disease mouse model

Cas9 nuclease介导的CAG/CTG重复序列缩短与亨廷顿病小鼠模型表型改善相关

Science Translational Medicine
IF14.6
2026-10-210
PRE
Alvaro Murillo; Melanie Alpaugh; Ruban Rex Peter Durairaj; Emma L. Randall; Meghan Larin; Laura Heraty; Alys N. Aston; Alysha S. Taylor; Alex Mas Monteys; Nina Stöberl; Aeverie E. R. Heuchan; Pascale Aeschlimann; Kyle Fears; Christian Landles; Georgina F. Osborne; Antoine Mangin; Soumyasree Bhattacharyya; Emmanouil Metzakopian; Nicholas D. Allen; Jack Puymirat; Gillian P. Bates; Beverly L. Davidson; Francesca Cicchetti; Mariah J. Lelos; Vincent Dion
Blocking somatic repeat expansion and lowering huntingtin by RNAi synergize to attenuate Huntington’s disease pathogenesis in mice

通过RNAi阻断体细胞重复序列扩增和降低亨廷蛋白协同减轻亨廷顿病在小鼠中的病理发生

Science Translational Medicine
IF14.6
2026-08-120
PRE
Jillian Belgrad; Ashley Summers; Christian Landles; Jonathan R. Greene; Samuel Hildebrand; Emily Knox; Ellen Sapp; Nozomi Yamada; Raymond Furgal; Rachael Miller; Georgina F. Osborne; Kathryn Chase; Eric Luu; Jason Freedman; Brianna Bramato; Nicholas McHugh; Israel Nnah; Vicky Benoit; Daniel O’Reilly; Paul Greer; Gillian P. Bates; Thomas F. Vogt; Ramee Lee; David Howland; Marian DiFiglia; Neil Aronin; Anastasia Khvorova
Human-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7

人类特有序列特征通过剪接因子SRSF7促进HTT外显子1的毒性错位处理

Nature Communications
IF15.7
2026-07-310
OA
Camilla Maffezzini; Raffaele Iennaco; Andrea Scolz; Simone Maestri; Christian Landles; Georgina F. Osborne; Marta M. Bronzini; Camilla Trovesi; Thomas Carzaniga; Luca Casiraghi; Jimena Quiros Ramirez; Thomas F. Vogt; Dan P. Felsenfeld; Tommaso Bellini; Chiara Zuccato; Gillian P. Bates; Elena Cattaneo
Molecular features of a Huntington's disease knock-in minipig

亨廷顿病基因敲入小型猪的分子特征

Disease Models & Mechanisms
IF3.3
2026-05-010
PRE
Kolesnikova, Anastasiia; Sathasivam, Kirupa; Tusi, Solaleh Khoramian; Landles, Christian; Osborne, Georgina F.; Kovalenko, Marina; Gillis, Tammy; Kamenna, Eva; Sekac, David; Nguyen, Duong The; Valekova, Ivona; Juhas, Stefan; Juhasova, Jana; Levinska, Bozena; Baxa, Monika; Motlik, Jan; Klima, Jiri; Howland, David; Wheeler, Vanessa C.; Bates, Gillian P.; Ellederova, Zdenka
Lowering the HTT1a transcript as an effective therapy for Huntington’s disease in a knockin mouse model

降低HTT1a转录本作为亨廷顿病在敲入小鼠模型中的有效疗法

Science Translational Medicine
IF14.6
2026-03-180
PRE
Aikaterini Smaragdi Papadopoulou; Julia Alterman; Christian Landles; Edward J. Smith; Faith Conroy; Jemima Phillips; Maria Canibano-Pico; Iulia M. Nita; Georgina F. Osborne; Arzo Iqbal; Sarah G. Aldous; Marie K. Bondulich; Casandra Gomez-Paredes; Kirupa Sathasivam; Daniel O’Reilly; Dimas Echeverria; Konstantin Bobkov; Jonathan R. Greene; Neil Aronin; Anastasia Khvorova; Gillian P. Bates

研究方向

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K
Kirupa Sathasivam
H 指数:26论文数:93被引数:7,977
C
Christian Landles
H 指数:23论文数:61被引数:4,415
S
Sarah J. Tabrizi
H 指数:100论文数:728被引数:3.7万
G
Georgina F Osborne
H 指数:15论文数:38被引数:1,089
B
Ben Woodman
H 指数:29论文数:64被引数:4,414
A
Andreas Neueder
H 指数:22论文数:79被引数:1,967
E
Erich E. Wanker
H 指数:72论文数:262被引数:2.7万
E
Edward J. Smith
H 指数:23论文数:97被引数:2,061
M
Marie K. Bondulich
H 指数:12论文数:26被引数:1,126
D
Donna L. Smith
H 指数:36论文数:122被引数:5,265