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收藏Discovery of Arginine Ethyl Ester as Polyglutamine Aggregation Inhibitor: Conformational Transitioning of Huntingtin N-Terminus Augments Aggregation Suppression
Singh, Virender; Patel, Kinjal A.; Sharma, Raj Kumar; Patil, Pratik R.; Joshi, Abhayraj S.; Parihar, Rashmi; Athilingam, Thamarailingam; Sinha, Neeraj; Ganesh, Subramaniam; Sinha, Pradip; Roy, Ipsita; Thakur, Ashwani Kumar
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收藏Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux
Rai, Anupama; Singh, Pankaj Kumar; Singh, Virender; Kumar, Vipendra; Mishra, Rohit; Thakur, Ashwani Kumar; Mahadevan, Anita; Shankar, Susarla Krishna; Jana, Nihar Ranjan; Ganesh, Subramaniam
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收藏Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism
Thakur, Ashwani K.; Jayaraman, Murali; Mishra, Rakesh; Thakur, Monika; Chellgren, Veronique M.; Byeon, In-Ja L.; Anjum, Dalaver H.; Kodali, Ravindra; Creamer, Trevor P.; Conway, James F.; Gronenborn, Angela M.; Wetzel, Ronald
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