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J

Juanita Lopez

Institute of Cancer Research
H指数:36
被引数:1.0万

个人简介

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教育背景

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工作经历

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荣誉奖项

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IAP antagonist tolinapant (ASTX660) in combination with pembrolizumab in advanced solid tumors: a phase I trial

IAP拮抗剂托利那潘特（ASTX660）联合帕博利珠单抗治疗晚期实体瘤：一项I期临床试验

Nature Communications
IF15.7
2026-09-300
OA
Crescens Tiu; Wing Yau; Tencho Tenev; Daniel Lionarons; Ching Leung; Victoria Sanchez-Perez; Giovanni Codacci-Pisanelli; Xiaoran Lai; Anna Zachariou; Aasia Hussain; Toby Prout; Mona Parmar; Bindu Baikady; Maria Goicoechea; Scott Layzell; Naomi Guppy; Ioannis Roxanis; Thomas Lund; Diego Carlos Dos Reis; Camila Pereira Almeida; Tatiany Luiza Silveira; Ana Ferreira; Bora Gurel; Claudia Bertan; Mateus Crespo; Penny Flohr; Ann-Marie Baker; Trevor Graham; Luis Zapata; Claudio Salas; Soham Mandal; Alan Dunlop; Martin Sims; George Ward; Tomoko Smyth; Simone Jueliger; Matthew Davis; Ilya Potapov; Aram Oganesian; Danna Chan; Mattias Leino; Subham Basu; Andre Samson; James M. Murphy; Nina Tunariu; Edward W. Johnston; Alistair Ring; Nick Turner; Andrew N. J. Tutt; Amanda Swain; Anna Minchom; Adam Sharp; Alec Paschalis; Udai Banerji; Johann de Bono; Bristi Basu; Christina Yap; Syed Haider; Juanita Lopez; Pascal Meier
Safety and efficacy of ceralasertib, an ATR kinase inhibitor, combined with olaparib: dose escalation in advanced solid tumours and dose expansion in advanced breast cancer

西拉帕替尼（一种ATR激酶抑制剂）联合奥拉帕尼的安全性与有效性：在晚期实体瘤中的剂量递增研究及在晚期乳腺癌中的剂量扩展研究

British Journal of Cancer
IF6.8
2026-09-300
OAAI
Juanita S. Lopez; Seock-Ah Im; Sophie Postel-Vinay; Mario Campone; Anthony B. El-Khoueiry; Wassim Abida; Tobias Arkenau; Keun-Wook Lee; Sun Young Rha; Duncan I. Jodrell; Rebecca Roylance; Itziar Irurzun-Arana; Gemma N. Jones; Natalia Lukashchuk; Christine Stephens; Conor Norris; Arsène-Bienvenu Loembé; Emma Dean; Matthew G. Krebs
53 Analysis of translational challenges across 19 brain tumour therapeutic development programmes: Insights from the BTR-NTA accelerator

53 跨越19个脑肿瘤治疗开发计划的转化挑战分析：来自BTR-NTA加速器的见解

Neuro-Oncology
IF13.4
2026-08-270
OAAI
Kate Munro, Ms; Eloise Lines, Miss; Nicky Huskens, Dr; Katie Bushby, Professor; Karen Noble, Dr; Paul Brennan, Professor; Helen Bulbeck, Dr; Petra Hamerlik, Professor; Darren Hargrave, Professor; Edward Kaye, Dr; Dione Kobayashi, Dr; Ryan Mathew, Mr; Javad Nazarian, Professor; Ruman Rahman, Professor; Artie Romero, Professor; Erik Sulman, Dr; Juanita Lopez, Dr; Kanneboyina Nagaraju, Professor
129 Electroactive drug delivery for local glioblastoma treatment

129 电活性药物递送用于局部胶质母细胞瘤治疗

Neuro-Oncology
IF13.4
2026-08-270
OAAI
Joshua Killilea, Mr; Immi Van Der Auweraert, Miss; Gary Shaw, Mr; Harveena Padda, Miss; Holly Briggs, Miss; Une Kontrimaite, Miss; Leire Landeira Suquia, Miss; Rosalie De Ferm, Miss; Lucia Moreno Gimeno, Miss; Phoebe McCrorie, Mrs; Estelle Cuttaz, Miss; Aaron Lee, Mr; Giovanni Carlo Miceli, Mr; Stuart Smith, Mr; Dong-Hyun Kim, Dr; Ruman Rahman, Professor; Juanita Lopez, Professor; Roberto Portillo Lara, Dr; Josef Goding, Dr; Heiko Wurdak, Dr; Ryan Mathew, Mr; Christopher Chapman, Dr; Rylie Green, Professor
Phase 1 study of ceralasertib, an ATR kinase inhibitor, in combination with durvalumab in patients with recurrent or metastatic NSCLC or HNSCC

I期研究：评估ceralasertib（一种ATR激酶抑制剂）联合durvalumab治疗复发或转移性NSCLC或HNSCC患者的疗效。

British Journal of Cancer
IF6.8
2026-03-310
OAAI
Juanita S. Lopez; Kevin J. Harrington; Seock-Ah Im; Keun-Wook Lee; Sophie Postel-Vinay; Jacob S. Thomas; Natalia Lukashchuk; Sophie E. Willis; Itziar Irurzun-Arana; Benjamin Webb; Jyoti Nehra; Alan Lau; Arsène-Bienvenu Loembé; Emma Dean; Matthew G. Krebs
Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology

Experimental Cancer Medicine Centre (ECMC)网络关于泛癌种测序的共识基因面板的提案：一种德尔菲方法

British Journal of Cancer
IF6.8
2025-11-080
OAAI
Richard Phillips; Bristi Basu; Zohra Butt; Mounia Beloueche; Natalie Cook; Simon J. Crabb; Alastair Greystoke; Darren Hargrave; Robert Jones; Muhammad Yasin Kureeman; Juanita Lopez; Claire McKeeve; Magdalena Meissner; Brent O’Carrigan; Eileen E. Parkes; Milind Ronghe; Patricia Roxburgh; Debashis Sarker; Kienan I. Savage; Paul H. S. Shaw; Stefan Symeonides; Deborah A. Tweddle; Aditi Vedi; Harriet S. Walter; Joanna Zabkiewicz; Gary W. Middleton; Andrew D. Beggs
Supporting development of novel brain tumour therapies through global collaboration: early insights from a novel therapeutics accelerator

通过全球合作支持新型脑瘤疗法的开发：来自新型疗法加速器的早期见解

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Aitken, Charlotte; Bushby, Katie; Goetz, Camille; Huskens, Nicky; Noble, Karen; Hamerlik, Petra; Kaye, Edward; Kobayashi, Dione; Matthew, Ryan; Nazarian, Javad; Plummer, Ruth; Rahman, Ruman; Romero, Artie; Lopez, Juanita; Nagaraju, Kanneboyina
Phase I/II Study of AXL-Specific Antibody-Drug Conjugate Enapotamab Vedotin in Patients with Advanced Solid Tumors

晚期实体瘤患者AXL特异性抗体药物偶联物Enapotamab Vedotin的I/II期研究

Cancer Research Communications
IF0
2025-11-010
OA
Rohrberg, Kristoffer Staal; Lopez, Juanita S.; Milhem, Mohammed M.; Blank, Christian U.; Reijers, Irene; Thistlethwaite, Fiona; Plummer, Ruth; Piha-Paul, Sarina A.; Janne, Pasi A.; Shum, Elaine; Shaw, Heather M.; Debruyne, Philip R.; Lao, Cristopher; Baurain, Jean-Francois; Choe, Jennifer H.; Gort, Eelke; Zhao, Yujie; Jerusalem, Guy; Schoffski, Patrick; Chen, Andrew William; Cohen, Eric A.; Mankowski, Walter C.; Roshkovan, Leonid; Katz, Sharyn I.; Kontos, Despina; Brady, Lauren K.; Qutaish, Mohammed; Castro, Patricia Garrido; Pencheva, Nora; Bajaj, Gaurav; Fu, Yali; Windfeld, Kristian; Reiter, Panagiota; Jure-Kunkel, Maria; Higgs, Brandon W.; Amiri, Katayoun I.; Ahmadi, Tahamtan; Forssmann, Ulf; Ramalingam, Suresh S.; Vergote, Ignace
PHASE 1B SAFETY RESULTS OF VORASIDENIB IN COMBINATION WITH TEMOZOLOMIDE IN PATIENTS WITH MUTANT IDH1 OR IDH2 GLIOMA

1B期试验中，vorasidenib与temozolomide联合治疗携带IDH1或IDH2突变的胶质瘤患者的安全性结果。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
de la Fuente, Macarena, I; Cloughesy, Timothy F.; Touat, Mehdi; Lopez, Juanita; McBain, Catherine; Steelman, Lori; Hassan, Islam; Jain, Payal; Man, Albert; Abshire, Michelle; Knipstein, Jeffrey; Mellinghoff, Ingo; Wen, Patrick Y.
Lenvatinib plus pembrolizumab for patients with previously treated select solid tumors: Results from the phase 2 LEAP-005 study recurrent glioblastoma cohort

伦伐替尼联合帕博利珠单抗用于先前接受过治疗的特定实体瘤患者：来自LEAP-005研究复发胶质母细胞瘤队列的2期研究结果

Cancer
IF5.1
2025-08-130
OAAI
Sun Young Rha MD, PhD; Eduardo Castanon MD; Sanjeev Gill MBBS, FRACP; Helene Senellart MD; Juanita Lopez MD, PhD; Iván Márquez-Rodas MD, PhD; Iván Victoria MD; Tae Min Kim MD, PhD; Zarnie Lwin MBBS, FCP, FRACP; Michael C. Burger MD; Matteo Simonelli MD; Philippe A. Cassier MD, PhD; Andrew E. Hendifar MD; Paolo A. Ascierto MD; Corina Dutcus MD; Chinyere E. Okpara PhD; Razi Ghori PhD; Fan Jin MD; Roman Groisberg MD; Luis Villanueva MD, MSc
Defactinib with avutometinib in patients with solid tumors: the phase 1 FRAME trial

德法替尼联合阿瓦替尼治疗实体瘤患者: 1期框架试验

Nature Medicine
IF50
2025-06-270
OAAI
Susana Banerjee; Matthew G. Krebs; Alastair Greystoke; Alvaro Ingles Garces; Vicky Sanchez Perez; Angelika Terbuch; Rajiv Shinde; Reece Caldwell; Rafael Grochot; Mahtab Rouhifard; Ruth Ruddle; Bora Gurel; Karen Swales; Nina Tunariu; Toby Prout; Mona Parmar; Stefan Symeonides; Jan Rekowski; Christina Yap; Adam Sharp; Alec Paschalis; Juanita Lopez; Anna Minchom; Johann Sebastian de Bono; Udai Banerji
A phase 1/2a dose-finding study and biomarker assessment of oral lisavanbulin in patients with high-grade glioma or glioblastoma

一项关于口服lisavanbulin的剂量探索研究（1/2a期）及其生物标志物评估，用于治疗高级别胶质瘤或胶质母细胞瘤患者

Cell Reports Medicine
IF10.6
2025-06-170
OA
Juanita Suzanne Lopez; Simon Haefliger; Ruth Plummer; Paul M. Clement; Thomas R. Jeffry Evans; Heinz Läubli; Patrick Roth; Rebecca Kristeleit; Lucy Brazil; Ghazaleh Tabatabai; Antje Wick; Benjamin Wunderlich; Kirk Beebe; Joel Robert Eisner; Heidi Lane; Marc Engelhardt; Thomas Kaindl; Peter Hau; Thomas Hundsberger; Joachim Steinbach
Phase 1 study of IMCnyeso, a T cell receptor bispecific ImmTAC targeting NY-ESO-1-expressing malignancies

I期IMCnyeso研究，该研究是一种靶向NY-ESO-1表达性恶性病变的T细胞受体双特异性ImmTAC。

CELL REPORTS MEDICINE
IF10.6
2025-04-010
OAAI
Lopez, Juanita S.; Milhem, Mohammed; Butler, Marcus O.; Thistlethwaite, Fiona; Van Tine, Brian A.; D'Angelo, Sandra P.; Johnson, Melissa L.; Sato, Takami; Arkenau, Hendrik-Tobias; Edukulla, Ramakrishna; Wustner, Jason; Marshall, Shannon; Rodon, Jordi
Phase I safety and efficacy of brenetafusp, a PRAME x CD3 ImmTAC T cell engager, in platinum resistant ovarian cancer (PROC)

I期安全性及有效性研究：brenetafusp（一种PRAME x CD3 ImmTAC T细胞结合剂）在铂耐药卵巢癌（PROC）中的应用

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Friedman, C.; Williams, A. De Burgh; Lopez, J. S.; Ouali, K.; Middleton, M. R.; Thistlethwaite, F.; Hamid, O.; Izar, B.; Garcia, V. Moreno; Johnson, M. L.; Davar, D.; Martin-Liberal, J.; Roxburgh, P.; Moore, K. N.; Olson, D.; Rottey, S.; Kirk, P. B.; Yuan, Y.; Marshall, S.; Yeku, O.
Leveraging innate and adaptive immunity with AFM24 and atezolizumab in metastatic gastric cancer

利用AFM24和atezolizumab增强固有免疫和适应性免疫在转移性胃癌中的应用

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Santa Gadea, O. Saavedra; Oberoi, A.; Lopez, J. S.; Cervantes, A.; Ponz-Sarvise, M.; Kim, H. R.; El-Khoueiry, A. B.; Shim, B.; Kim, J. W.; Boni, V.; Lugowska, I.; Szczylik, C.; Rogowski, W.; Mandziuk, S.; Ramlau, R.; Gaertner, U.; Lutkewitz, S.; Schuetz, D.; Emig, M.; Morales-Espinosa, D.
Initial results from a phase I/II study of BT7480, a novel nectin-4/CD137 bicycle tumor-targeted immune cell agonist, in patients (pts) with advanced solid tumors

BT7480的一项I/II期研究初步结果，BT7480是一种新型的nectin-4/CD137双环肿瘤靶向免疫细胞激动剂，用于治疗晚期实体瘤患者(pts)。

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Papadopoulos, K. P.; Dowlati, A.; Lopez, J. S.; Rodon, J.; Spira, A. I.; Stein, M.; Zibelman, M.; Feliu, W. I. Ortuzar; Dickson, A.; De, A.; Gu, X.; Cohen, H.; Li, M.; Bader, J.; Bray, C.; Santos, S.; Smith, J.; Lis, R.; Evans, T. R. J.

研究方向

暂未获取到该数据
U
Udai Banerji
H 指数:52论文数:647被引数:1.2万
J
Johann S. de Bono
H 指数:160论文数:2,491被引数:13.5万
R
Ruth Plummer
H 指数:59论文数:604被引数:1.3万
N
Nina Tunariu
H 指数:50论文数:440被引数:1.8万
A
Anna Minchom
H 指数:26论文数:301被引数:2,596
T
Timothy A. Yap
H 指数:77论文数:1,361被引数:2.6万
M
Mona Parmar
H 指数:13论文数:81被引数:688
R
Raghav Sundar
H 指数:42论文数:382被引数:6,519
R
Rebecca Kristeleit
H 指数:41论文数:350被引数:8,706
S
Stan B. Kaye
H 指数:78论文数:433被引数:2.9万