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M

Mona Parmar

The Institute of Cancer Research
H指数:13
被引数:689

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IAP antagonist tolinapant (ASTX660) in combination with pembrolizumab in advanced solid tumors: a phase I trial

IAP拮抗剂托利那潘特（ASTX660）联合帕博利珠单抗治疗晚期实体瘤：一项I期临床试验

Nature Communications
IF15.7
2026-09-300
OA
Crescens Tiu; Wing Yau; Tencho Tenev; Daniel Lionarons; Ching Leung; Victoria Sanchez-Perez; Giovanni Codacci-Pisanelli; Xiaoran Lai; Anna Zachariou; Aasia Hussain; Toby Prout; Mona Parmar; Bindu Baikady; Maria Goicoechea; Scott Layzell; Naomi Guppy; Ioannis Roxanis; Thomas Lund; Diego Carlos Dos Reis; Camila Pereira Almeida; Tatiany Luiza Silveira; Ana Ferreira; Bora Gurel; Claudia Bertan; Mateus Crespo; Penny Flohr; Ann-Marie Baker; Trevor Graham; Luis Zapata; Claudio Salas; Soham Mandal; Alan Dunlop; Martin Sims; George Ward; Tomoko Smyth; Simone Jueliger; Matthew Davis; Ilya Potapov; Aram Oganesian; Danna Chan; Mattias Leino; Subham Basu; Andre Samson; James M. Murphy; Nina Tunariu; Edward W. Johnston; Alistair Ring; Nick Turner; Andrew N. J. Tutt; Amanda Swain; Anna Minchom; Adam Sharp; Alec Paschalis; Udai Banerji; Johann de Bono; Bristi Basu; Christina Yap; Syed Haider; Juanita Lopez; Pascal Meier
Defactinib with avutometinib in patients with solid tumors: the phase 1 FRAME trial

德法替尼联合阿瓦替尼治疗实体瘤患者: 1期框架试验

Nature Medicine
IF50
2025-06-270
OAAI
Susana Banerjee; Matthew G. Krebs; Alastair Greystoke; Alvaro Ingles Garces; Vicky Sanchez Perez; Angelika Terbuch; Rajiv Shinde; Reece Caldwell; Rafael Grochot; Mahtab Rouhifard; Ruth Ruddle; Bora Gurel; Karen Swales; Nina Tunariu; Toby Prout; Mona Parmar; Stefan Symeonides; Jan Rekowski; Christina Yap; Adam Sharp; Alec Paschalis; Juanita Lopez; Anna Minchom; Johann Sebastian de Bono; Udai Banerji
Proof-of-concept and preliminary efficacy of triple IAP blockade to maximize immunogenic cell death and induce efficient adaptive immune response: First report on the ASTEROID phase 1 trial
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Tiu, Crescens; Yau, Wing; Sanchez-Perez, Victoria; Codacci-Pisanelli, Giovanni; Leung, Ching; Andrews, Eden S.; Basu, Bristi; Zachariou, Anna; Prout, Toby; Parmar, Mona; Turner, Alison; Lai, Xiaoran; Yin, Zhulin; Swales, Karen E.; Haider, Syed; Lund, Thomas; Dos Reis, Diego C.; Silveira, Tatiany L.; Dunlop, Alan S.; Baker, Ann-Marie; Gurel, Bora; Ferreira, Ana; Bertan, Claudia; Tunariu, Nina; Johnston, Edward W.; Ring, Alistair; Tenev, Tencho; Smyth, Tomoko; Jueliger, Simone; Banerji, Udai; de Bono, Johann S.; Paschalis, Alec; Sharp, Adam; Minchom, Anna; Yap, Christina; Meier, Pascal; Lopez, Juanita S.
Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance

靶向髓系趋化逆转前列腺癌治疗耐药

Nature
IF48.5
2023-10-160
OAAI
Christina Guo; Adam Sharp; Bora Gurel; Mateus Crespo; Ines Figueiredo; Suneil Jain; Ursula Vogl; Jan Rekowski; Mahtab Rouhifard; Lewis Gallagher; Wei Yuan; Suzanne Carreira; Khobe Chandran; Alec Paschalis; Ilaria Colombo; Anastasios Stathis; Claudia Bertan; George Seed; Jane Goodall; Florence Raynaud; Ruth Ruddle; Karen E. Swales; Jason Malia; Denisa Bogdan; Crescens Tiu; Reece Caldwell; Caterina Aversa; Ana Ferreira; Antje Neeb; Nina Tunariu; Daniel Westaby; Juliet Carmichael; Maria Dolores Fenor de la Maza; Christina Yap; Ruth Matthews; Hannah Badham; Toby Prout; Alison Turner; Mona Parmar; Holly Tovey; Ruth Riisnaes; Penny Flohr; Jesus Gil; David Waugh; Shaun Decordova; Anna Schlag; Bianca Calì; Andrea Alimonti; Johann S. de Bono
Preliminary evidence of antitumor activity of Ipatasertib (Ipat) and Atezolizumab (A) in glioblastoma (GBM) patients (pts) with PTEN loss in the Phase 1 Ice-CAP trial (NCT03673787)
CANCER RESEARCH
IF16.6
2023-04-142
PRE
Tiu, Crescens; Yau, Wing Hing; Welsh, Liam C.; Jones, Timothy L.; Zachariou, Anna; Prout, Toby; Parmar, Mona; Turner, Alison J.; Daly, Robert W.; Yap, Christina; Crespo, Mateus; Gurel, Bora; Riisnaes, Ruth M.; DeCordova, Shaun A.; Swales, Karen E.; Banerji, Udai; Minchom, Anna R.; Sharp, Adam; de Bono, Johann S.; Lopez, Juanita S.
Phase 1, dose-escalation study of guadecitabine (SGI-110) in combination with pembrolizumab in patients with solid tumors

guadecitabine (SGI-110) 联合pembrolizumab治疗实体瘤患者的1期剂量递增研究

JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2022-06-1826
OAAI
Papadatos-Pastos, Dionysis; Yuan, Wei; Pal, Abhijit; Crespo, Mateus; Ferreira, Ana; Gurel, Bora; Prout, Toby; Ameratunga, Malaka; Chenard-Poirier, Maxime; Curcean, Andra; Bertan, Claudia; Baker, Chloe; Miranda, Susana; Masrour, Nahal; Chen, Wentin; Pereira, Rita; Figueiredo, Ines; Morilla, Ricardo; Jenkins, Ben; Zachariou, Anna; Riisnaes, Ruth; Parmar, Mona; Turner, Alison; Carreira, Suzanne; Yap, Christina; Brown, Robert; Tunariu, Nina; Banerji, Udai; Lopez, Juanita; de Bono, Johann; Minchom, Anna
Triplet Therapy with Palbociclib, Taselisib, and fulvestrant in PIK3CA-Mutant Breast Cancer and Doublet Palbociclib and Taselisib in Pathway-Mutant Solid Cancers
CANCER DISCOVERY
IF33.3
2021-01-0645
OAAI
Pascual, Javier; Lim, Joline S. J.; Macpherson, Iain R.; Armstrong, Anne C.; Ring, Alistair; Okines, Alicia F. C.; Cutts, Rosalind J.; Herrera-Abreu, Maria Teresa; Garcia-Murillas, Isaac; Pearson, Alex; Hrebien, Sarah; Gevensleben, Heidrun; Proszek, Paula Z.; Hubank, Michael; Hills, Margaret; King, Jenny; Parmar, Mona; Prout, Toby; Finneran, Laura; Malia, Jason; Swales, Karen E.; Ruddle, Ruth; Raynaud, Florence, I; Turner, Alison; Hall, Emma; Yap, Timothy A.; Lopez, Juanita S.; Turner, Nicholas C.
Phase I Trial of the PARP Inhibitor Olaparib and AKT Inhibitor Capivasertib in Patients with BRCA1/2- and Non-BRCA1/2-Mutant Cancers

PARP抑制剂Olaparib和AKT抑制剂Capivasertib在BRCA1/2和Non-BRCA1/2突变型癌症患者中的I期试验

CANCER DISCOVERY
IF33.3
2020-10-0192
OAAI
Yap, Timothy A.; Kristeleit, Rebecca; Michalarea, Vasiliki; Pettitt, Stephen J.; Lim, Joline S. J.; Carreira, Suzanne; Roda, Desamparados; Miller, Rowan; Riisnaes, Ruth; Miranda, Susana; Figueiredo, Ines; Rodrigues, Daniel Nava; Ward, Sarah; Matthews, Ruth; Parmar, Mona; Turner, Alison; Tunariu, Nina; Chopra, Neha; Gevensleben, Heidrun; Turner, Nicholas C.; Ruddle, Ruth; Raynaud, Florence, I; Decordova, Shaun; Swales, Karen E.; Finneran, Laura; Hall, Emma; Rugman, Paul; Lindemann, Justin P. O.; Foxley, Andrew; Lord, Christopher J.; Banerji, Udai; Plummer, Ruth; Basu, Bristi; Lopez, Juanita S.; Drew, Yvette; de Bono, Johann S.
Vistusertib (dual m-TORC1/2 inhibitor) in combination with paclitaxel in patients with high-grade serous ovarian and squamous non-small-cell lung cancer
ANNALS OF ONCOLOGY
IF65.4
2018-09-0125
OAAI
Basu, B.; Krebs, M. G.; Sundar, R.; Wilson, R. H.; Spicer, J.; Jones, R.; Brada, M.; Talbot, D. C.; Steele, N.; Garces, A. H. Ingles; Brugger, W.; Harrington, E. A.; Evans, J.; Hall, E.; Tovey, H.; de Oliveira, F. M.; Carreira, S.; Swales, K.; Ruddle, R.; Raynaud, F. I.; Purchase, B.; Dawes, J. C.; Parmar, M.; Turner, A. J.; Tunariu, N.; Banerjee, S.; de Bono, J. S.; Banerji, U.
Phase I trial combining the PARP inhibitor olaparib (01a) and AKT inhibitor AZD5363 (AZD) in germline (g)BRCA and non-BRCA mutant (m) advanced cancer patients (pts) incorporating noninvasive monitoring of cancer mutations
CANCER RESEARCH
IF16.6
2016-07-1510
PRE
Michalarea, Vasiliki; Roda, Desam; Drew, Yvette; Carreira, Suzanne; O'Carrigan, Brent S.; Shaw, Heather; Roux, Rene; Kumar, Sanjeev; Ward, Sarah; Parmar, Mona; Turner, Alison; Hall, Emma; Fandos, Sonia Serrano; Perez, Raquel; Tunariu, Nina; Raynaud, Florence; Cullberg, Marie; Foxley, Andrew; Lindemann, Justin P. O.; Pass, Martin; Rugman, Paul; Lopez, Juanita S.; Banerji, Udai; Basu, Bristi; Plummer, Ruth; Kristeleit, Rebecca; de Bono, Johann S.; Yap, Timothy A.
Accelerated phase I trial of two schedules of the combination of the PARP inhibitor olaparib and AKT inhibitor AZD5363 using a novel intrapatient dose escalation design in advanced cancer patients
CANCER RESEARCH
IF16.6
2015-08-016
PRE
Michalarea, Vasiliki; Lorente, David; Lopez, Juanita; Carreira, Suzanne; Hassam, Hasina; Parmar, Mona; Sathiyayogan, Nitharsan; Turner, Alison; Hall, Emma; Fandos, Sonia Serrano; Seeramreddi, Satyanarayana; Decordova, Shaun; Swales, Karen; Ruddle, Ruth; Raynaud, Florence; Tunariu, Nina; Attard, Gerhardt; Molife, L. Rhoda; Banerji, Udai; Plummer, Ruth; de Bono, Johann S.; Yap, Timothy A.

研究方向

暂未获取到该数据
U
Udai Banerji
H 指数:52论文数:647被引数:1.2万
J
Johann S. de Bono
H 指数:160论文数:2,491被引数:13.5万
N
Nina Tunariu
H 指数:50论文数:440被引数:1.8万
A
Alison Turner
H 指数:13论文数:60被引数:834
J
Juanita Lopez
H 指数:36论文数:332被引数:1.0万
K
Karen E. Swales
H 指数:24论文数:117被引数:1,971
E
Emma Hall
H 指数:69论文数:502被引数:2.5万
A
Anna Minchom
H 指数:26论文数:301被引数:2,600
C
Christina Yap
H 指数:38论文数:235被引数:7,150
S
Suzanne Carreira
H 指数:49论文数:437被引数:1.5万