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E

Evangelos D. Michelakis

university of alberta

76H指数
278论文数
2.3W被引数
收录论文 136
发表时间
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Discovery of a snail hibernation-inducer offering hibernation-like cardioprotection through metabolic rewiring and autophagy in mice发现一种蜗牛休眠诱导剂，可通过代谢重编程和自噬在小鼠中提供类休眠的心脏保护
errNature Communications
IF15.7
err2026-06-10
err0
errOAAI
errJiyuan Piao; Yongneng Zhang; Yuan-Yuan Zhao; Patrick Hanington; Jacob Hambrook; Yongsheng Liu; John R. Ussher; Seyed Amirhossein Tabatabaei Dakhili; Gopinath Sutendra; Evangelos D. Michelakis
err分享
err收藏
Selective translation of ZNF281 as part of the integrated stress response system has therapeutic relevance for cardio-oncologyZNF281的选择性翻译作为整合应激反应系统的一部分，对肿瘤心脏病学具有治疗相关性
errScience Translational Medicine
IF14.6
err2026-04-15
err0
PREAI
errMaria Areli Lorenzana-Carrillo; Saymon Tejay; Guocheng Huang; Joseph Nanoa; Yuan-Yuan Zhao; Cory Wagg; Farah Eaton; Michelle Mendiola Pla; Dawn E. Bowles; Adam Kinnaird; Evangelos D. Michelakis; Seyed Amirhossein Tabatabaei Dakhili; John R. Ussher; Gopinath Sutendra
err分享
err收藏
Efficacy of anakinra in reducing progression to organ dysfunction in patients with pneumonia (INSPIRE): a randomised, double-blind, placebo-controlled, phase IIa trial阿那白滞素在减少肺炎患者器官功能障碍进展中的疗效（INSPIRE）：一项随机、双盲、安慰剂对照的IIa期试验
errThe Lancet Regional Health - Europe
IF0
err2025-12-29
err0
errOAAI
errGeorgios Tavoulareas; Olga Kontakou-Zoniou; Nikolaos Antonakos; Elisavet Tasouli; George Adamis; Nikolaos Kakavoulis; Evangelos Michelakis; Ilias Skopelitis; Konstantina Dakou; Christos Psarrakis; Panagiotis Koufargyris; Myrto Astriti; Styliani Sympardi; Evangelos J. Giamarellos-Bourboulis
err分享
err收藏
Cysteine Oxidation of a Redox Hub within Complex I can Facilitate Electron Transport Chain Supercomplex Formation泛素复合物I内一个氧化还原中心半胱氨酸的氧化可以促进电子传递链超复合物的形成
errJournal of Biological Chemistry
IF3.9
err2025-08-05
err0
errOAAI
errRuntai Chen; Seyed Amirhossein Tabatabaei Dakhili; Rokas Geruskis; Yuan Yuan Zhao; Steven Lockhart; Lusine Tonoyan; Arno Siraki; Guocheng Huang; Adam Kinnaird; Darren H. Freed; Shelley Minteer; Evangelos D. Michelakis; John R. Ussher; Gopinath Sutendra
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err收藏
Tumour initiated purinergic signalling promotes cardiomyocyte RBFOX1 degradation and cardiotoxicity from DNA damaging anticancer agents肿瘤起始的嘌呤能信号促进心肌细胞RBFOX1降解及DNA损伤抗癌剂的心脏毒性
errNature Communications
IF15.7
err2025-07-25
err0
errOAAI
errSaymon Tejay; Maria Areli Lorenzana-Carrillo; Guocheng Huang; Seyed Amirhossein Tabatabaei Dakhili; Yuan -Yuan Zhao; Farah Eaton; Michelle Mendiola Pla; Dawn E. Bowles; Adam Kinnaird; D. Ian Paterson; Edith Pituskin; John R. Ussher; Evangelos D. Michelakis; Gopinath Sutendra
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err收藏
Three-dimensional spatial localization and volume estimation of prostate tumors using 18F-PSMA-1007 PET/CT versus multiparametric MRI使用18F-PSMA-1007 PET/CT与多参数MRI对前列腺肿瘤进行三维空间定位和体积评估
errEUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
IF7.6
err2024-12-27
err0
errOAAI
errHuang, Guocheng; Albers, Patrick; Mookerji, Nikhile; Pfanner, Tyler; Hui, Amaris; Mittal, Rohan; Broomfield, Stacey; Dean, Lucas; St. Martin, Blair; Jacobsen, Niels-Erik; Evans, Howard; Gao, Yuan; Hung, Ryan; Abele, Jonathan; Dromparis, Peter; Lima, Joema Felipe; Bismar, Tarek A.; Michelakis, Evangelos; Sutendra, Gopinath; Wuest, Frank; Tu, Wendy; Adam, Benjamin A.; Fung, Christopher; Ghosh, Sunita; Tamm, Alexander; Kinnaird, Adam
err分享
err收藏
Myofibroblast transition and loss of UCP2 in a rat model and a human pulmonary hypertension cohort underline right ventricular decompensation: potential value of a loss -of-function UCP2 SNP肌成纤维细胞转分化及大鼠模型和人类肺动脉高压队列中UCP2的缺失凸显了右心室失代偿：UCP2功能缺失型SNP的潜在价值
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errZhang, Yongneng; Haromy, Alois; Liu, Yongsheng; Zhao, Yuan Yuan; Bonnet, Sandra Breuils; Bonnet, Sebastien; Bowles, Dawn; Sutendra, Gopinath; Michelakis, Evangelos
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err收藏
A novel small molecule synthesized based on a snail hibernation model induces hibernation in mouse fibroblasts and perfused hearts一种基于蜗牛冬眠模型合成的新型小分子可诱导小鼠成纤维细胞和灌注心脏进入冬眠状态
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errPiao, Jiyuan; Zhang, Yongneng; Zhao, Yuan Yuan; Hannington, Patrick; Dakhili, Seyed Amirhossein Tabatabaei; Ussher, John; Sutendra, Gopinath; Michelakis, Evangelos
err分享
err收藏
TRIM35 Monoubiquitinates H2B in Cardiac Cells, Implications for Heart Failure
errCIRCULATION RESEARCH
IF16.2
err2024-07-05
err0
PREAI
errLorenzana-Carrillo, Maria Areli; Tejay, Saymon; Nanoa, Joseph; Huang, Guocheng; Liu, Yongsheng; Haromy, Alois; Zhao, Yuan Yuan; Pla, Michelle Mendiola; Bowles, Dawn E.; Kinnaird, Adam; Michelakis, Evangelos D.; Sutendra, Gopinath
err分享
err收藏
The Effects of Oxygen-Derived Free-Radical Scavengers During Normothermic Ex-Situ Heart Perfusion
errASAIO JOURNAL
IF2.3
err2024-03-08
err0
PREAI
errQi, Xiao; Hatami, Sanaz; Bozso, Sabin; Wang, Xiuhua; Saleme, Bruno; Nagendran, Jayan; Michelakis, Evangelos; Sutendra, Gopinath; Freed, Darren H.
err分享
err收藏
A Critical Contribution of Cardiac Myofibroblasts and a Predictive Role of UCP2 SNPs in the RV Decompensation in Pulmonary Hypertension
errCIRCULATION
IF38.6
err2023-11-07
err0
PREAI
errZhang, Yongneng; Carrillo, Maria A. Lorenzana; Tejay, Saymon; Haromy, Alois S.; Liu, Yongsheng; Zhao, Yuan Yuan; Sutendra, Gopinath; Michelakis, Evangelos D.
err分享
err收藏
Fasting increases susceptibility to acute myocardial ischaemia/reperfusion injury through a sirtuin-3 mediated increase in fatty acid oxidation禁食通过sirtuin-3介导的脂肪酸氧化增加对急性心肌缺血/再灌注损伤的易感性
errSCIENTIFIC REPORTS
IF3.9
err2022-11-29
err4
errOAAI
errHall, Andrew R. R.; Karwi, Qutuba G. G.; Kumar, Sanjeev; Dongworth, Rachel; Aksentijevic, Dunja; Altamimi, Tariq R. R.; Fridianto, Kevin Timothy; Chinda, Kroekkiat; Hernandez-Resendiz, Sauri; Mahmood, Mohammad U. U.; Michelakis, Evangelos; Ramachandra, Chrishan J. J.; Ching, Jianhong; Vicencio, Jose M. M.; Shattock, Michael J. J.; Kovalik, Jean-Paul; Yellon, Derek M. M.; Lopaschuk, Gary; Hausenloy, Derek J. J.
err分享
err收藏
TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2022-11-02
err11
PREAI
errLorenzana-Carrillo, Maria Areli; Gopal, Keshav; Byrne, Nikole J.; Tejay, Saymon; Saleme, Bruno; Das, Subhash K.; Zhang, Yongneng; Haromy, Alois; Eaton, Farah; Pla, Michelle Mendiola; Bowles, Dawn E.; Dyck, Jason R. B.; Ussher, John R.; Michelakis, Evangelos D.; Sutendra, Gopinath
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Atrial Shunt Devices in Patients With Heart Failure and Preserved or Mildly Reduced Ejection Fraction and the Pulmonary Circulation: Promises and Concerns
errCIRCULATION
IF38.6
err2022-05-24
err2
errOAAI
errSaunders, Alexandra; Michelakis, Evangelos
err分享
err收藏
Changing cell fate in the wall of pulmonary arteries
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2022-05-04
err0
PREAI
errZhang, Yongneng; Michelakis, Evangelos D.
err分享
err收藏
Oral treprostinil improves pulmonary vascular compliance in pulmonary arterial hypertension
errRESPIRATORY MEDICINE
IF3.1
err2022-03-01
err11
errOAAI
errKhan, Akram; White, R. James; Meyer, Gisela; Zamudio, Tomas R. Pulido; Jerjes-Sanchez, Carlos; Johnson, Dana; Grover, Rob; Broderick, Meredith; Ousmanou, Aliou; Holdstock, Louis; Michelakis, Evangelos
err分享
err收藏
MFN2-driven mitochondria-to-nucleus tethering allows a non-canonical nuclear entry pathway of the mitochondrial pyruvate dehydrogenase complex
errMOLECULAR CELL
IF16.6
err2022-03-01
err27
errOAAI
errZervopoulos, Sotirios D.; Boukouris, Aristeidis E.; Saleme, Bruno; Haromy, Alois; Tejay, Saymon; Sutendra, Gopinath; Michelakis, Evangelos D.
err分享
err收藏
A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
errCELL REPORTS
IF6.9
err2022-03-01
err8
PREAI
errBoukouris, Aristeidis E.; Zhang, Yongneng; Saleme, Bruno; Kinnaird, Adam; Zhao, Yuan Yuan; Liu, Yongsheng; Zervopoulos, Sotirios D.; Das, Subhash K.; Mittal, Rohan D.; Haromy, Alois; Lorenzana-Carrillo, Maria Areli; Krysler, Amanda R.; Cromwell, Christopher R.; Hubbard, Basil P.; Sutendra, Gopinath; Michelakis, Evangelos D.
err分享
err收藏
SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes
errJOURNAL OF THE AMERICAN HEART ASSOCIATION
IF5.3
err2021-12-07
err9
errOAAI
errZhang, Yongneng; Zervopoulos, Sotirios D.; Boukouris, Aristeidis E.; Lorenzana-Carrillo, Maria Areli; Saleme, Bruno; Webster, Linda; Liu, Yongsheng; Haromy, Alois; Dakhili, Seyed Amirhossein Tabatabaei; Ussher, John R.; Sutendra, Gopinath; Michelakis, Evangelos D.
err分享
err收藏
A Phase-2 NIH-sponsored Randomized Clinical Trial of Rituximab in Scleroderma-associated Pulmonary Arterial Hypertension Did Not Reach Significance for Its Endpoints End of Story? Not So Fast!
errAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
err2021-07-15
err8
errOAAI
errZhang, Yongneng; Michelakis, Evangelos D.
err分享
err收藏

研究方向

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合作学者
合作期刊
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D
Derek M. Yellon
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