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E

Evangelos D. Michelakis

University of Alberta
H指数:76
被引数:2.2万

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Selective translation of ZNF281 as part of the integrated stress response system has therapeutic relevance for cardio-oncology

ZNF281的选择性翻译作为整合应激反应系统的一部分，对肿瘤心脏病学具有治疗相关性

Science Translational Medicine
IF14.6
2026-04-150
PRE
Maria Areli Lorenzana-Carrillo; Saymon Tejay; Guocheng Huang; Joseph Nanoa; Yuan-Yuan Zhao; Cory Wagg; Farah Eaton; Michelle Mendiola Pla; Dawn E. Bowles; Adam Kinnaird; Evangelos D. Michelakis; Seyed Amirhossein Tabatabaei Dakhili; John R. Ussher; Gopinath Sutendra
Efficacy of anakinra in reducing progression to organ dysfunction in patients with pneumonia (INSPIRE): a randomised, double-blind, placebo-controlled, phase IIa trial

阿那白滞素在减少肺炎患者器官功能障碍进展中的疗效（INSPIRE）：一项随机、双盲、安慰剂对照的IIa期试验

The Lancet Regional Health - Europe
IF0
2025-12-290
OAAI
Georgios Tavoulareas; Olga Kontakou-Zoniou; Nikolaos Antonakos; Elisavet Tasouli; George Adamis; Nikolaos Kakavoulis; Evangelos Michelakis; Ilias Skopelitis; Konstantina Dakou; Christos Psarrakis; Panagiotis Koufargyris; Myrto Astriti; Styliani Sympardi; Evangelos J. Giamarellos-Bourboulis
Cysteine Oxidation of a Redox Hub within Complex I can Facilitate Electron Transport Chain Supercomplex Formation

泛素复合物I内一个氧化还原中心半胱氨酸的氧化可以促进电子传递链超复合物的形成

Journal of Biological Chemistry
IF3.9
2025-08-050
OA
Runtai Chen; Seyed Amirhossein Tabatabaei Dakhili; Rokas Geruskis; Yuan Yuan Zhao; Steven Lockhart; Lusine Tonoyan; Arno Siraki; Guocheng Huang; Adam Kinnaird; Darren H. Freed; Shelley Minteer; Evangelos D. Michelakis; John R. Ussher; Gopinath Sutendra
Tumour initiated purinergic signalling promotes cardiomyocyte RBFOX1 degradation and cardiotoxicity from DNA damaging anticancer agents

肿瘤起始的嘌呤能信号促进心肌细胞RBFOX1降解及DNA损伤抗癌剂的心脏毒性

Nature Communications
IF15.7
2025-07-250
OA
Saymon Tejay; Maria Areli Lorenzana-Carrillo; Guocheng Huang; Seyed Amirhossein Tabatabaei Dakhili; Yuan -Yuan Zhao; Farah Eaton; Michelle Mendiola Pla; Dawn E. Bowles; Adam Kinnaird; D. Ian Paterson; Edith Pituskin; John R. Ussher; Evangelos D. Michelakis; Gopinath Sutendra
Three-dimensional spatial localization and volume estimation of prostate tumors using 18F-PSMA-1007 PET/CT versus multiparametric MRI

使用18F-PSMA-1007 PET/CT与多参数MRI对前列腺肿瘤进行三维空间定位和体积评估

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
IF7.6
2024-12-270
OA
Huang, Guocheng; Albers, Patrick; Mookerji, Nikhile; Pfanner, Tyler; Hui, Amaris; Mittal, Rohan; Broomfield, Stacey; Dean, Lucas; St. Martin, Blair; Jacobsen, Niels-Erik; Evans, Howard; Gao, Yuan; Hung, Ryan; Abele, Jonathan; Dromparis, Peter; Lima, Joema Felipe; Bismar, Tarek A.; Michelakis, Evangelos; Sutendra, Gopinath; Wuest, Frank; Tu, Wendy; Adam, Benjamin A.; Fung, Christopher; Ghosh, Sunita; Tamm, Alexander; Kinnaird, Adam
Myofibroblast transition and loss of UCP2 in a rat model and a human pulmonary hypertension cohort underline right ventricular decompensation: potential value of a loss -of-function UCP2 SNP

肌成纤维细胞转分化及大鼠模型和人类肺动脉高压队列中UCP2的缺失凸显了右心室失代偿：UCP2功能缺失型SNP的潜在价值

CIRCULATION
IF38.6
2024-11-120
PRE
Zhang, Yongneng; Haromy, Alois; Liu, Yongsheng; Zhao, Yuan Yuan; Bonnet, Sandra Breuils; Bonnet, Sebastien; Bowles, Dawn; Sutendra, Gopinath; Michelakis, Evangelos
Fasting increases susceptibility to acute myocardial ischaemia/reperfusion injury through a sirtuin-3 mediated increase in fatty acid oxidation

禁食通过sirtuin-3介导的脂肪酸氧化增加对急性心肌缺血/再灌注损伤的易感性

SCIENTIFIC REPORTS
IF3.9
2022-11-294
OAAI
Hall, Andrew R. R.; Karwi, Qutuba G. G.; Kumar, Sanjeev; Dongworth, Rachel; Aksentijevic, Dunja; Altamimi, Tariq R. R.; Fridianto, Kevin Timothy; Chinda, Kroekkiat; Hernandez-Resendiz, Sauri; Mahmood, Mohammad U. U.; Michelakis, Evangelos; Ramachandra, Chrishan J. J.; Ching, Jianhong; Vicencio, Jose M. M.; Shattock, Michael J. J.; Kovalik, Jean-Paul; Yellon, Derek M. M.; Lopaschuk, Gary; Hausenloy, Derek J. J.
SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes
JOURNAL OF THE AMERICAN HEART ASSOCIATION
IF5.3
2021-12-079
OAAI
Zhang, Yongneng; Zervopoulos, Sotirios D.; Boukouris, Aristeidis E.; Lorenzana-Carrillo, Maria Areli; Saleme, Bruno; Webster, Linda; Liu, Yongsheng; Haromy, Alois; Dakhili, Seyed Amirhossein Tabatabaei; Ussher, John R.; Sutendra, Gopinath; Michelakis, Evangelos D.

研究方向

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S
Stephen L. Archer
H 指数:104论文数:497被引数:4.6万
G
Gopinath Sutendra
H 指数:29论文数:107被引数:5,123
A
Alois Haromy
H 指数:28论文数:69被引数:8,427
P
Peter Dromparis
H 指数:18论文数:80被引数:3,461
S
Sébastien Bonnet
H 指数:70论文数:438被引数:1.6万
K
Kyoko Hashimoto
H 指数:35论文数:101被引数:7,893
A
Adam Kinnaird
H 指数:20论文数:163被引数:2,846
R
Roxane Paulin
H 指数:39论文数:154被引数:6,083
J
Jason R.B. Dyck
H 指数:90论文数:417被引数:2.7万
J
Jayan Nagendran
H 指数:31论文数:246被引数:4,062