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MCL-1 safeguards activated hair follicle stem cells to enable adult hair regeneration MCL-1保护活化的毛囊干细胞，以实现成年毛发再生 Chin, Hui San; Cheng, Jinming; Hsu, Shih Han; Lum, Guo Guang; Zaldivia, Maria T. K.; Nelameham, Sarmilla; Guo, Fusheng; Mallavarapu, Keerthana; Jackling, Felicity C.; Yang, Jicheng; Tan, Jonathan S. L.; Sampath, Prabha; Barker, Nick; Smyth, Gordon K.; Lindeman, Geoffrey J.; Strasser, Andreas; Visvader, Jane E.; Chen, Yunshun; Chen, Ting; Fu, Nai Yang 分享 收藏
Hormone-responsive progenitors have a unique identity and exhibit high motility during mammary morphogenesis 激素反应性祖细胞具有独特的身份，并在乳腺形态发生过程中表现出很高的运动性 Dawson, Caleb A.; Milevskiy, Michael J. G.; Capaldo, Bianca D.; Yip, Raymond K. H.; Song, Xiaoyu; Vaillant, Francois; Prokopuk, Lexie; Jackling, Felicity C.; Smyth, Gordon K.; Chen, Yunshun; Lindeman, Geoffrey J.; Visvader, Jane E. 分享 收藏
PALVEN: A phase Ib study of palbociclib, letrozole and venetoclax in ER and BCL2-positive metastatic breast cancer PALVEN：一项关于palbociclib、letrozole和venetoclax在ER和BCL2阳性转移性乳腺癌中的 Ib 期研究 Muttiah, C.; Martin, F.; Christie, M.; Dawson, S-J.; Desai, J.; Lal, L.; Moodie, K.; Murugasu, A.; Phan, P.; Rosenthal, M.; Travers, A.; Visvader, J.; Whittle, J. R.; Lindeman, G. 分享 收藏
Inhibition of lysine acetyltransferase KAT6 in ER+HER2- metastatic breast cancer: a phase 1 trial (jun, 10.1038/s41591-024-03060-0, 2024) Mukohara, Toru; Park, Yeon Hee; Sommerhalder, David; Yonemori, Kan; Hamilton, Erika; Kim, Sung-Bae; Kim, Jee Hyun; Iwata, Hiroji; Yamashita, Toshinari; Layman, Rachel M.; Mita, Monica; Clay, Timothy; Chae, Yee Soo; Oakman, Catherine; Yan, Fengting; Kim, Gun Min; Im, Seock-Ah; Lindeman, Geoffrey J.; Rugo, Hope S.; Liyanage, Marlon; Saul, Michelle; Le Corre, Christophe; Skoura, Athanasia; Liu, Li; Li, Meng; LoRusso, Patricia M. 分享 收藏
Inhibition of lysine acetyltransferase KAT6 in ER+HER2- metastatic breast cancer: a phase 1 trial Mukohara, Toru; Park, Yeon Hee; Sommerhalder, David; Yonemori, Kan; Hamilton, Erika; Kim, Sung-Bae; Kim, Jee Hyun; Iwata, Hiroji; Yamashita, Toshinari; Layman, Rachel M.; Mita, Monica; Clay, Timothy; Chae, Yee Soo; Oakman, Catherine; Yan, Fengting; Kim, Gun Min; Im, Seock-Ah; Lindeman, Geoffrey J.; Rugo, Hope S.; Liyanage, Marlon; Saul, Michelle; Le Corre, Christophe; Skoura, Athanasia; Liu, Li; Li, Meng; LoRusso, Patricia M. 分享 收藏
The MAGIC study: Universal whole genome tumour and germline sequencing of newly diagnosed breast cancer identifies a high proportion of ER plus BRCA-like tumours Campbell, Ian; Devereux, Lisa; Hogg, Kirsten; Lal, Luxi; Sinclair, Michelle; Stafford, Lesley; Zethoven, Magnus; Skandarajah, Anita; James, Paul; Lindeman, Geoffrey; Mann, Bruce; De Silva, Dilanka 分享 收藏
Universal genetic testing for women with newly diagnosed breast cancer identified many mutations, impacted clinical management and caused no psychological distress to patients 对新诊断的乳腺癌女性进行的通用基因检测发现了许多突变，影响了临床管理，并没有给患者造成心理困扰。 De Silva, Dilanka; Stafford, Lesley; Skandarajah, Anita; Sinclair, Michelle; Devereux, Lisa; Hogg, Kirsten; Kentwell, Maira; Park, Allan; Lal, Luxi; Zethoven, Magnus; Jayawardena, Madawa; Chan, Fiona; James, Paul; Lindeman, Geoffrey; Campbell, Ian; Mann, Bruce 分享 收藏
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Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers 鉴定异常管腔祖细胞和mTORC1作为BRCA2突变携带者的潜在乳腺癌预防靶标 Joyce, Rachel; Pascual, Rosa; Heitink, Luuk; Capaldo, Bianca D.; Vaillant, Francois; Christie, Michael; Tsai, Minhsuang; Surgenor, Elliot; Anttila, Casey J. A.; Rajasekhar, Pradeep; Jackling, Felicity C.; Trussart, Marie; Milevskiy, Michael J. G.; Song, Xiaoyu; Li, Mengbo; Teh, Charis E.; Gray, Daniel H. D.; Smyth, Gordon K.; Chen, Yunshun; Lindeman, Geoffrey J.; Visvader, Jane E. 分享 收藏
Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells 三维基因组结构协调乳腺上皮细胞谱系规范的关键调控因子 Milevskiy, Michael J. G.; Coughlan, Hannah D.; Kane, Serena R.; Johanson, Timothy M.; Kordafshari, Somayeh; Chan, Wing Fuk; Tsai, Minhsuang; Surgenor, Elliot; Wilcox, Stephen; Allan, Rhys S.; Chen, Yunshun; Lindeman, Geoffrey J.; Smyth, Gordon K.; Visvader, Jane E. 分享 收藏
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer 发现一种高效，选择性，口服生物利用度的KAT6A/B组蛋白乙酰转移酶抑制剂，对KAT6A-high ER乳腺癌有效 Sharma, Shikhar; Chung, Chi-Yeh; Uryu, Sean; Petrovic, Jelena; Cao, Joan; Rickard, Amanda; Nady, Nataliya; Greasley, Samantha; Johnson, Eric; Brodsky, Oleg; Khan, Showkhin; Wang, Hui; Wang, Zhenxiong; Zhang, Yong; Tsaparikos, Konstantinos; Chen, Lei; Mazurek, Anthony; Lapek, John; Kung, Pei-Pei; Sutton, Scott; Richardson, Paul F.; Greenwald, Eric C.; Yamazaki, Shinji; Jones, Rhys; Maegley, Karen A.; Bingham, Patrick; Lam, Hieu; Stupple, Alexandra E.; Kamal, Aileen; Chueh, Anderly; Cuzzupe, Anthony; Morrow, Benjamin J.; Ren, Bin; Carrasco-Pozo, Catalina; Tan, Chin Wee; Bhuva, Dharmesh D.; Allan, Elizabeth; Surgenor, Elliot; Vaillant, Francois; Pehlivanoglu, Havva; Falk, Hendrik; Whittle, James R.; Newman, Janet; Cursons, Joseph; Doherty, Judy P.; White, Karen L.; Macpherson, Laura; Devlin, Mark; Dennis, Matthew L.; Hattarki, Meghan K.; De Silva, Melanie; Camerino, Michelle A.; Butler, Miriam S.; Dolezal, Olan; Pilling, Patricia; Foitzik, Richard; Stupple, Paul A.; Lagiakos, H. Rachel; Walker, Scott R.; Hediyeh-Zadeh, Soroor; Nuttall, Stewart; Spall, Sukhdeep; Charman, Susan A.; Connor, Theresa; Peat, Thomas S.; Avery, Vicky M.; Bozikis, Ylva E.; Yang, Yuqing; Zhang, Ming; Monahan, Brendon J.; Voss, Anne K.; Street, Ian P.; Dawson, Sarah-Jane; Dawson, Mark A.; Lindeman, Geoffrey J.; Davis, Melissa J.; Visvader, Jane E.; Paul, Thomas A. 分享 收藏
Combined PARP and WEE1 inhibition triggers anti-tumor immune response in BRCA1/2 wildtype triple-negative breast cancer PARP和WEE1联合抑制触发BRCA1/2野生型三阴性乳腺癌的抗肿瘤免疫反应 Teo, Zhi Ling; O'Connor, Mark J.; Versaci, Stephanie; Clarke, Kylie A.; Brown, Emmaline R.; Percy, Luke W.; Kuykhoven, Keilly; Mintoff, Christopher P.; Savas, Peter; Virassamy, Balaji; Luen, Stephen J.; Byrne, Ann; Sant, Sneha; Lindeman, Geoffrey J.; Darcy, Phillip K.; Loi, Sherene 分享 收藏
Venetoclax treatment in patients with cancer has limited impact on circulating T and NK cells 维尼托克治疗癌症患者对循环T和NK细胞的影响有限 Teh, Charis E.; Peng, Hongke; Luo, Meng-Xiao; Tan, Tania; Trussart, Marie; Howson, Lauren J.; Chua, Chong Chyn; Muttiah, Christine; Brown, Fiona; Ritchie, Matthew E.; Wei, Andrew H.; Roberts, Andrew W.; Bryant, Vanessa L.; Anderson, Mary Ann; Lindeman, Geoffrey J.; Huang, David C. S.; Thijssen, Rachel; Gray, Daniel H. D. 分享 收藏
PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants 致病性BRCA1/2变异对乳腺癌患者预后的预测效度 Muranen, Taru; Morra, Anna; Khan, Sofia R.; Barnes, Daniel K.; Bolla, Manjeet; Dennis, Joe; Keeman, Renske; Leslie, Goska T.; Parsons, Michael; Wang, Qin U.; Ahearn, Thomas; Aittomaeki, Kristiina L.; Andrulis, Irene K.; Arun, Banu; Behrens, Sabine; Bialkowska, Katarzyna E.; Bojesen, Stig J.; Camp, Nicola; Chang-Claude, Jenny; Czene, Kamila; Devilee, Peter M.; Domchek, Susan M.; Dunning, Alison; Engel, Christoph; Evans, D. Gareth; Gago-Dominguez, Manuela; Garcia-Closas, Montserrat; Gerdes, Anne-Marie; Glendon, Gord; Guenel, Pascal; Hahnen, Eric; Hamann, Ute; Hanson, Helen J.; Hooning, Maartje; Hoppe, Reiner; Izatt, Louise; Jakubowska, Anna A.; James, Paul N.; Kristensen, Vessela; Lalloo, Fiona J.; Lindeman, Geoffrey; Mannermaa, Arto; Margolin, Sara L.; Neuhausen, Susan G.; Newman, William; Peterlongo, Paolo; Phillips, Kelly-Anne; Pujana, Miquel Angel; Rantala, Johanna; Ronlund, Karina; Saloustros, Emmanouil K.; Schmutzler, Rita; Schneeweiss, Andreas F.; Singer, Christian; Suvanto, Maija; Tan, Yen Yen R.; Teixeira, Manuel; Thomassen, Mads; Tischkowitz, Marc; Tripathi, Vishakha; Wappenschmidt, Barbara; Zhao, Emily F.; Easton, Douglas C.; Antoniou, Antonis; Chenevix-Trench, Georgia; Pharoah, Paul D. P. K.; Schmidt, Marjanka; Blomqvist, Carl; Nevanlinna, Heli 分享 收藏
Universal genetic testing for women with newly diagnosed breast cancer in the context of multidisciplinary team care 在多学科团队护理的背景下，对新诊断的乳腺癌女性进行通用基因检测 De Silva, Dilanka L.; Stafford, Lesley; Skandarajah, Anita R.; Sinclair, Michelle; Devereux, Lisa; Hogg, Kirsten; Kentwell, Maira; Park, Allan; Lal, Luxi; Zethoven, Magnus; Jayawardana, Madawa W.; Chan, Fiona; Butow, Phyllis N.; James, Paul A.; Mann, G. Bruce; Campbell, Ian G.; Lindeman, Geoffrey J. 分享 收藏
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Gata-3 Negatively Regulates the Tumor-Initiating Capacity of Mammary Luminal Progenitor Cells and Targets the Putative Tumor Suppressor Caspase-14 Gata-3负调节乳腺腔祖细胞的肿瘤启动能力，并靶向假定的肿瘤抑制Caspase-14 Asselin-Labat, Marie-Liesse; Sutherland, Kate D.; Vaillant, Francois; Gyorki, David E.; Wu, Di; Holroyd, Sheridan; Breslin, Kelsey; Ward, Teresa; Shi, Wei; Bath, Mary L.; Deb, Siddhartha; Fox, Stephen B.; Smyth, Gordon K.; Lindeman, Geoffrey J.; Visvader, Jane E. 分享 收藏
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