Yunshun Chen - Publications, H-index & Citations

Yunshun Chen

the walter and eliza hall institute of medical research

28H指数

79论文数

1.9W被引数

收录论文 35

发表时间

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease 坏死性凋亡到凋亡的信号轴是炎症性肠病的病理基础

Science

IF45.8

2026-08-27

PREAI

Jiyi Pang; Aysha H. Al-Ani; Komal M. Patel; Yunzhuo Zhou; Samuel N. Young; Jinjin Chen; Isabella Kong; Marilou Barrios; James A. Rickard; Siqi Chen; Xiuquan Ma; Farzaneh Shojaee; Seong-Beom Kim; Siavash Foroughi; Wayne Cawthorne; Annette V. Jacobsen; Asha Jois; Ashley L. Weir; Lachlan W. Whitehead; Pradeep Rajasekhar; Christopher R. Horne; Ruqian Lyu; Lucy J. Mather; Raymond K. H. Yip; Ellen Tsui; Imadh Azeez; Tao Tan; Weiwei Liang; Suresh Sivanesan; Andrew Metz; Ash Patwardhan; Natalie Shea; Guru Iyngkaran; Daniel Schneider; Alexander T. Elford; William Beattie; Finlay Macrae; Gianmaria Liccardi; Henning Walczak; Yuxia Zhang; Oliver M. Sieber; Tim Spelman; Lisa Giulino-Roth; Michael Christie; Yunshun Chen; Kelly L. Rogers; Rory Bowden; Sandra E. Nicholson; Kate E. Lawlor; Edwin D. Hawkins; Britt Christensen; Andre L. Samson; James E. Vince; James M. Murphy

hoodscanR: profiling single-cell neighborhoods in spatial transcriptomics data HoodscanR：空间转录组数据中单细胞邻域分析

Bioinformatics

IF5.4

2026-08-13

OAAI

Ning Liu; Jarryd Martin; Dharmesh D Bhuva; Jinjin Chen; Mengbo Li; Samuel C Lee; Malvika Kharbanda; Jinming Cheng; Ahmed Mohamed; Arutha Kulasinghe; Yunshun Chen; Chin Wee Tan; Fuyi Li; Jose M Polo; Melissa J Davis; null

Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease 多尺度分析及骨骼疾病细胞和遗传决定因素的功能验证

Nature Genetics

IF29

2026-07-10

OAAI

Ryan C. Chai; Mischa Lundberg; Bernard Freudenthal; James T. Smith; Andrew P. Boughton; Yuandan Zhang; Kaitlyn A. Flynn; Monika Frysz; Alexander P. Corr; Weng Hua Khoo; Davide Komla-Ebri; Michael R. G. Dack; Siobhan E. Guilfoyle; John G. Logan; Natalie C. Butterfield; Victoria D. Leitch; Andrea S. Pollard; Riikka E. Mäkitie; Nathaniel Bradford; Lorenzo Ramos-Mucci; Amaia Vilas-Zornoza; Yunshun Chen; Raymond K. H. Yip; Jeremy Er; Siew Zhuan Tan; Michelle M. McDonald; Scott E. Youlten; C. Marcelo Sergio; Ariel Castro-Martinez; Shelley G. Young; Elena Skorokhodova; David M. Evans; Joseph E. Powell; Christiaan A. de Leeuw; Adam D. Ewing; John A. Eisman; Robert D. Blank; Tri Giang Phan; Anne K. Lagendijk; Edwin D. Hawkins; Horng Lii Oh; Rebecca E. McIntyre; Edith M. Hessel; Jake P. Taylor-King; Paul A. Baldock; Emma L. Duncan; Graham R. Williams; J. H. Duncan Bassett; Peter I. Croucher; John P. Kemp

Dividing out quantification uncertainty enables assessment of differential transcript usage with limma and edgeR 除掉量化不确定性使得能够使用limma和edgeR评估差异转录本使用情况

NUCLEIC ACIDS RESEARCH

IF13.1

2025-12-11

PREAI

Baldoni, Pedro L.; Chen, Lizhong; Li, Mengbo; Chen, Yunshun; Smyth, Gordon K.

stPipe: a flexible and streamlined R/Bioconductor pipeline for preprocessing sequencing-based spatial transcriptomics data stPipe: 一种灵活且高效的R/Bioconductor流程，用于预处理基于测序的空间转录组学数据

NAR GENOMICS AND BIOINFORMATICS

IF2.8

2025-12-01

OAAI

Xu, Yang; Sargeant, Callum J.; You, Yue; You, Yupei; Su, Shian; Wang, Changqing; Tian, Luyi; Chen, Yunshun; Ritchie, Matthew E.

Incorporating exon–exon junction reads enhances differential splicing detection 整合外显子-外显子连接读数增强差异剪接检测

BMC Bioinformatics

IF3.3

2025-08-25

PREAI

Mai T. Pham; Michael J. G. Milevskiy; Jane E. Visvader; Yunshun Chen

Profiling the spatial architecture of multiple myeloma in human bone marrow trephine biopsy specimens with spatial transcriptomics 利用空间转录组学对人类骨髓穿刺活检标本中多发性骨髓瘤的空间架构进行剖析

Blood

IF23.1

2025-07-14

OAAI

Raymond K. H. Yip; Jeremy Er; Lei Qin; Quoc Hoang Nguyen; Allan Motyer; Joel S. Rimes; Amanda Light; Ruvimbo D. Mishi; Ling Ling; Casey J. A. Anttila; Ellen Tsui; Daniela Amann-Zalcenstein; Mark R. Dowling; Kelly L. Rogers; Rory Bowden; Yunshun Chen; Simon J. Harrison; Edwin D. Hawkins

Circulating immune cells exhibit distinct traits linked to metastatic burden in breast cancer 循环免疫细胞表现出与乳腺癌转移负荷相关的独特特征。

BREAST CANCER RESEARCH

IF5.6

2025-05-08

OAAI

Mangiola, S.; Brown, R.; Zhan, C.; Berthelet, J.; Guleria, S.; Liyanage, C.; Ostrouska, S.; Wilcox, J.; Merdas, M.; Fuge-Larsen, P.; Bell, C.; Schroder, J.; Mielke, L. A.; Mariadason, J. M.; Tsao, S. Chang-Hao; Chen, Y.; Yadav, V. K.; Vodala, S.; Anderson, R. L.; Merino, D.; Behren, A.; Yeo, B.; Papenfuss, A. T.; Pal, B.

Benchmarking spatial transcriptomics technologies with the multi-sample SpatialBenchVisium dataset 使用多样本SpatialBenchVisium数据集评估空间转录组学技术

GENOME BIOLOGY

IF9.4

2025-03-28

OAAI

Du, Mei R. M.; Wang, Changqing; Law, Charity W.; Amann-Zalcenstein, Daniela; Anttila, Casey J. A.; Ling, Ling; Hickey, Peter F.; Sargeant, Callum J.; Chen, Yunshun; Ioannidis, Lisa J.; Rajasekhar, Pradeep; Yip, Raymond K. H.; Rogers, Kelly L.; Hansen, Diana S.; Bowden, Rory; Ritchie, Matthew E.

MCL-1 safeguards activated hair follicle stem cells to enable adult hair regeneration MCL-1保护活化的毛囊干细胞，以实现成年毛发再生

NATURE COMMUNICATIONS

IF15.7

2025-03-22

OAAI

Chin, Hui San; Cheng, Jinming; Hsu, Shih Han; Lum, Guo Guang; Zaldivia, Maria T. K.; Nelameham, Sarmilla; Guo, Fusheng; Mallavarapu, Keerthana; Jackling, Felicity C.; Yang, Jicheng; Tan, Jonathan S. L.; Sampath, Prabha; Barker, Nick; Smyth, Gordon K.; Lindeman, Geoffrey J.; Strasser, Andreas; Visvader, Jane E.; Chen, Yunshun; Chen, Ting; Fu, Nai Yang

Hormone-responsive progenitors have a unique identity and exhibit high motility during mammary morphogenesis 激素反应性祖细胞具有独特的身份，并在乳腺形态发生过程中表现出很高的运动性

CELL REPORTS

IF6.9

2024-12-01

OAAI

Dawson, Caleb A.; Milevskiy, Michael J. G.; Capaldo, Bianca D.; Yip, Raymond K. H.; Song, Xiaoyu; Vaillant, Francois; Prokopuk, Lexie; Jackling, Felicity C.; Smyth, Gordon K.; Chen, Yunshun; Lindeman, Geoffrey J.; Visvader, Jane E.

Single-cell transcriptional atlas of human breast cancers and model systems

CLINICAL AND TRANSLATIONAL MEDICINE

IF6.8

2024-10-17

OAAI

Altman, Julia E.; Olex, Amy L.; Zboril, Emily K.; Walker, Carson J.; Boyd, David C.; Myrick, Rachel K.; Hairr, Nicole S.; Koblinski, Jennifer E.; Puchalapalli, Madhavi; Hu, Bin; Dozmorov, Mikhail G.; Chen, X. Steven; Chen, Yunshun; Perou, Charles M.; Lehmann, Brian D.; Visvader, Jane E.; Harrell, J. Chuck

Ehf controls mammary alveolar lineage differentiation and is a putative suppressor of breast tumorigenesis

DEVELOPMENTAL CELL

IF8.7

2024-08-01

OAAI

Nightingale, Rebecca; Reehorst, Camilla M.; Vukelic, Natalia; Papadopoulos, Nikolaos; Liao, Yang; Guleria, Shalini; Bell, Caroline; Vaillant, Francois; Paul, Sudip; Luk, Ian Y.; Dhillon, Amardeep S.; Jenkins, Laura J.; Morrow, Riley J.; Jackling, Felicity C.; Chand, Ashwini L.; Chisanga, David; Chen, Yunshun; Williams, David S.; Anderson, Robin L.; Ellis, Sarah; Meikle, Peter J.; Shi, Wei; Visvader, Jane E.; Pal, Bhupinder; Mariadason, John M.

Decoding breast cancer: Unraveling subtype and model differences through multi-model single-cell RNA sequencing data integration

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Altman, Julia E.; Walker, Carson J.; Zboril, Emily K.; Hairr, Nicole S.; Myrick, Rachel K.; Boyd, David C.; Koblenski, Jennifer E.; Puchalapalli, Madhavi; Hu, Bin; Dozmorov, Mikhail G.; Chen, Xi; Chen, Yunshun; Perou, Charles M.; Lehmann, Brian D.; Visvader, Jane E.; Olex, Amy L.; Harrell, J. Chuck

Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers 鉴定异常管腔祖细胞和mTORC1作为BRCA2突变携带者的潜在乳腺癌预防靶标

NATURE CELL BIOLOGY

IF19.1

2024-01-12

PREAI

Joyce, Rachel; Pascual, Rosa; Heitink, Luuk; Capaldo, Bianca D.; Vaillant, Francois; Christie, Michael; Tsai, Minhsuang; Surgenor, Elliot; Anttila, Casey J. A.; Rajasekhar, Pradeep; Jackling, Felicity C.; Trussart, Marie; Milevskiy, Michael J. G.; Song, Xiaoyu; Li, Mengbo; Teh, Charis E.; Gray, Daniel H. D.; Smyth, Gordon K.; Chen, Yunshun; Lindeman, Geoffrey J.; Visvader, Jane E.

Dividing out quantification uncertainty allows efficient assessment of differential transcript expression with edgeR

NUCLEIC ACIDS RESEARCH

IF13.1

2023-12-07

OAAI

Baldoni, Pedro L.; Chen, Yunshun; Hediyeh-zadeh, Soroor; Liao, Yang; Dong, Xueyi; Ritchie, Matthew E.; Shi, Wei; Smyth, Gordon K.

Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells 三维基因组结构协调乳腺上皮细胞谱系规范的关键调控因子

CELL GENOMICS

IF9

2023-11-01

OAAI

Milevskiy, Michael J. G.; Coughlan, Hannah D.; Kane, Serena R.; Johanson, Timothy M.; Kordafshari, Somayeh; Chan, Wing Fuk; Tsai, Minhsuang; Surgenor, Elliot; Wilcox, Stephen; Allan, Rhys S.; Chen, Yunshun; Lindeman, Geoffrey J.; Smyth, Gordon K.; Visvader, Jane E.

Benchmarking long-read RNA-sequencing analysis tools using in silico mixtures

NATURE METHODS

IF32.1

2023-10-02

OAAI

Dong, Xueyi; Du, Mei R. M.; Gouil, Quentin; Tian, Luyi; Jabbari, Jafar S.; Bowden, Rory; Baldoni, Pedro L.; Chen, Yunshun; Smyth, Gordon K.; Amarasinghe, Shanika L.; Law, Charity W.; Ritchie, Matthew E.

Activation of stably silenced genes by recruitment of a synthetic de-methylating module

NATURE COMMUNICATIONS

IF15.7

2022-09-23

OAAI

Chan, Wing Fuk; Coughlan, Hannah D.; Chen, Yunshun; Keenan, Christine R.; Smyth, Gordon K.; Perkins, Andrew C.; Johanson, Timothy M.; Allan, Rhys S.

Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death

CELL DEATH AND DIFFERENTIATION

IF15.4

2022-03-31

OAAI

El-Saafin, Farrah; Bergamasco, Maria, I; Chen, Yunshun; May, Rose E.; Esakky, Prabagaran; Hediyeh-zadeh, Soroor; Dixon, Mathew; Wilcox, Stephen; Davis, Melissa J.; Strasser, Andreas; Smyth, Gordon K.; Thomas, Tim; Voss, Anne K.

研究方向