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S

Samuel A. Kerk

university of michigan
H指数:20
被引数:2,113

个人简介

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教育背景

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工作经历

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荣誉奖项

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Glucose metabolism sustains aberrant STAT3 signaling in colorectal cancer through glycosylated local signaling factors

葡萄糖代谢通过糖基化局部信号因子维持结直肠癌中异常的STAT3信号传导

Science Signaling
IF6.6
2026-03-030
PRE
Kathryn Buscher; Kelsey Temprine; Christopher Mays; Noora Aabed; Samuel A. Kerk; Hannah N. Bell; Joseph A. Nieto Carrion; Harrison S. Greenbaum; Zheng Hong Lee; Varun Ponnusamy; Sadeesh K. Ramakrishnan; Costas A. Lyssiotis; Xiang Xue; Yatrik M. Shah
Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer
CELL METABOLISM
IF30.9
2023-01-0151
OAAI
Bell, Hannah N.; Huber, Amanda K.; Singhal, Rashi; Korimerla, Navyateja; Rebernick, Ryan J.; Kumar, Roshan; El-derany, Marwa O.; Sajjakulnukit, Peter; Das, Nupur K.; Kerk, Samuel A.; Solanki, Sumeet; James, Jadyn G.; Kim, Donghwan; Zhang, Li; Chen, Brandon; Mehra, Rohit; Frankel, Timothy L.; Gyorffy, Balazs; Fearon, Eric R.; di Magliano, Marina Pasca; Gonzalez, Frank J.; Banerjee, Ruma; Wahl, Daniel R.; Lyssiotis, Costas A.; Green, Michael; Shah, Yatrik M.
Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells

胰腺腺癌细胞的差异性整合应激反应和天冬酰胺产生驱动共生和治疗抗性

NATURE CANCER
IF28.5
2022-11-2133
OAAI
Halbrook, Christopher J.; Thurston, Galloway; Boyer, Seth; Anaraki, Cecily; Jimenez, Jennifer A.; McCarthy, Amy; Steele, Nina G.; Kerk, Samuel A.; Hong, Hanna S.; Lin, Lin; Law, Fiona V.; Felton, Catherine; Scipioni, Lorenzo; Sajjakulnukit, Peter; Andren, Anthony; Beutel, Alica K.; Singh, Rima; Nelson, Barbara S.; van den Bergh, Fran; Krall, Abigail S.; Mullen, Peter J.; Zhang, Li; Batra, Sandeep; Morton, Jennifer P.; Stanger, Ben Z.; Christofk, Heather R.; Digman, Michelle A.; Beard, Daniel A.; Viale, Andrea; Zhang, Ji; Crawford, Howard C.; Pasca di Magliano, Marina; Jorgensen, Claus; Lyssiotis, Costas A.
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context
ELIFE
IF0
2022-07-1147
OA
Kerk, Samuel A.; Lin, Lin; Myers, Amy L.; Sutton, Damien J.; Andren, Anthony; Sajjakulnukit, Peter; Zhang, Li; Zhang, Yaqing; Jimenez, Jennifer A.; Nelson, Barbara S.; Chen, Brandon; Robinson, Anthony; Thurston, Galloway; Kemp, Samantha B.; Steele, Nina G.; Hoffman, Megan T.; Wen, Hui-Ju; Long, Daniel; Ackenhusen, Sarah E.; Ramos, Johanna; Gao, Xiaohua; Nwosu, Zeribe C.; Galban, Stefanie; Halbrook, Christopher J.; Lombard, David B.; Piwnica-Worms, David R.; Ying, Haoqiang; di Magliano, Marina Pasca; Crawford, Howard C.; Shah, Yatrik M.; Lyssiotis, Costas A.
Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming

外源性KRAS信号通过成纤维细胞重编程塑造胰腺微环境

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
IF7.4
2022-01-0155
OAAI
Velez-Delgado, Ashley; Donahue, Katelyn L.; Brown, Kristee L.; Du, Wenting; Irizarry-Negron, Valerie; Menjivar, Rosa E.; Opsahl, Emily L. Lasse; Steele, Nina G.; The, Stephanie; Lazarus, Jenny; Sirihorachai, Veerin R.; Yan, Wei; Kemp, Samantha B.; Kerk, Samuel A.; Bollampally, Murali; Yang, Sion; Scales, Michael K.; Avritt, Faith R.; Lima, Fatima; Lyssiotis, Costas A.; Rao, Arvind; Crawford, Howard C.; Bednar, Filip; Frankel, Timothy L.; Allen, Benjamin L.; Zhang, Yaqing; di Magliano, Marina Pasca
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis
NATURE COMMUNICATIONS
IF15.7
2021-08-11169
OAAI
Kremer, Daniel M.; Nelson, Barbara S.; Lin, Lin; Yarosz, Emily L.; Halbrook, Christopher J.; Kerk, Samuel A.; Sajjakulnukit, Peter; Myers, Amy; Thurston, Galloway; Hou, Sean W.; Carpenter, Eileen S.; Andren, Anthony C.; Nwosu, Zeribe C.; Cusmano, Nicholas; Wisner, Stephanie; Mbah, Nneka E.; Shan, Mengrou; Das, Nupur K.; Magnuson, Brian; Little, Andrew C.; Savani, Milan R.; Ramos, Johanna; Gao, Tina; Sastra, Stephen A.; Palermo, Carmine F.; Badgley, Michael A.; Zhang, Li; Asara, John M.; McBrayer, Samuel K.; di Magliano, Marina Pasca; Crawford, Howard C.; Shah, Yatrik M.; Olive, Kenneth P.; Lyssiotis, Costas A.
Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress

结直肠癌细胞在营养应激下利用自噬维持线粒体代谢促进细胞增殖

JCI INSIGHT
IF6.1
2021-06-1728
OA
Devenport, Samantha N.; Singhal, Rashi; Radyk, Megan D.; Taranto, Joseph G.; Kerk, Samuel A.; Chen, Brandon; Goyert, Joshua W.; Jain, Chesta; Das, Nupur K.; Oravecz-Wilson, Katherine; Li Zhang; Greenson, Joel K.; Chen, Y. Eugene; Soleimanpour, Scott A.; Reddy, Pavan; Lyssiotis, Costas A.; Shah, Yatrik M.
Menin regulates the serine biosynthetic pathway in Ewing sarcoma
JOURNAL OF PATHOLOGY
IF5.2
2018-05-2837
OAAI
Svoboda, Laurie K.; Teh, Selina Shiqing K.; Sud, Sudha; Kerk, Samuel; Zebolsky, Aaron; Treichel, Sydney; Thomas, Dafydd; Halbrook, Christopher J.; Lee, Ho-Joon; Kremer, Daniel; Zhang, Li; Klossowski, Szymon; Bankhead, Armand R.; Magnuson, Brian; Ljungman, Mats; Cierpicki, Tomasz; Grembecka, Jolanta; Lyssiotis, Costas A.; Lawlor, Elizabeth R.

研究方向

暂未获取到该数据
C
Costas A. Lyssiotis
H 指数:79论文数:767被引数:3.2万
Y
Yatrik M. Shah
H 指数:69论文数:359被引数:1.5万
P
Peter Sajjakulnukit
H 指数:25论文数:241被引数:4,719
M
Marina Pasca di Magliano
H 指数:57论文数:722被引数:1.5万
张
张丽
H 指数:112论文数:4,086被引数:7.4万
C
Christopher J. Halbrook
H 指数:28论文数:146被引数:6,755
H
Howard C. Crawford
H 指数:73论文数:619被引数:1.9万
B
Brandon Chen
H 指数:17论文数:83被引数:1,532
N
Nupur K. Das
H 指数:20论文数:92被引数:2,757
R
Rashi Singhal
H 指数:15论文数:49被引数:1,700