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U

Uri Ben-David

Ruprecht Karls University Heidelberg
H指数:37
被引数:1.0万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Hypertranscription caused by p53 deficiency triggers nucleotide insufficiency that induces replication stress and genomic instability

p53缺失引起的超转录触发了核苷酸不足，进而诱导复制应激和基因组不稳定性

Molecular Cell
IF16.6
2026-09-010
OAAI
Zaatra, Wisam; Philippos, George; Smirnov, Petr; Milo, Shira; Otonicar, Jan; Chan, Michelle; Harel, Michal; Devens, Frauke; Goldberg, Tchelet; Eliassaf, Alexandra; Grimes, Karen; Sinai, Michal Irony-Tur; Sigismondo, Gianluca; Laue, Kathrin; Ben-David, Uri; Geiger, Tamar; Korbel, Jan O.; Krijgsveld, Jeroen; Shalev, Ori; Kerem, Batsheva; Ernst, Aurelie
p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism

p53失活通过SCD1上调和增加脂肪酸代谢驱动乳腺癌转移到大脑

Nature Genetics
IF29
2025-12-290
PRE
Kathrin Laue; Sabina Pozzi; Johanna Zerbib; Rebecca Bertolio; Yonatan Eliezer; Yael Cohen-Sharir; Tom Winkler; Manuel Caputo; Alessia A. Ricci; Lital Adler; Rami Khoury; Giuseppe Longobardi; Rachel Slutsky; Alicia I. Leikin-Frenkel; Shai Ovadia; Katharina Lange; Alessandra Rustighi; Silvano Piazza; Andrea Sacconi; Rayna Y. Magesh; Faith N. Keller; Jean Berthelet; Alexander Schäffer; Ron Saad; Sahar Israeli Dangoor; Karolina Szczepanowska; Iris Barshack; Yang Liao; Sergey Malitsky; Alexander Brandis; Thomas Broggini; Marcus Czabanka; Wei Shi; Delphine Merino; Emma V. Watson; Giovanni Blandino; Ayelet Erez; Ruth Ashery-Padan; Hind Medyouf; Luca Bertero; Giannino Del Sal; Ronit Satchi-Fainaro; Uri Ben-David
DeepTarget predicts anti-cancer mechanisms of action of small molecules by integrating drug and genetic screens

DeepTarget通过整合药物和基因筛选来预测小分子的抗肿瘤作用机制。

npj Precision Oncology
IF8
2025-11-050
OAAI
Sanju Sinha; Neelam Sinha; Marlenne Perales; Adi Tarrab; Trinh Nguyen; Lihe Liu; Thomas Cantore; Kyle Alvarez; Sumeet Patiyal; Sumit Mukherjee; Sanna Madan; Kevin Tharp; Jianhua Zhao; Ranjit Kumar; Greg Flanigan; John A. Beutler; Barry R. O’Keefe; Daoud Meerzaman; Uri Ben-David; Aniruddha J. Deshpande; Eytan Ruppin
Increased RNA and Protein Degradation Is Required for Counteracting Transcriptional Burden and Proteotoxic Stress in Human Aneuploid Cells
CANCER DISCOVERY
IF33.3
2024-09-090
OA
Ippolito, Marica Rosaria; Zerbib, Johanna; Eliezer, Yonatan; Reuveni, Eli; Vigano, Sonia; De Feudis, Giuseppina; Shulman, Eldad D.; Kadmon, Anouk Savir; Slutsky, Rachel; Chang, Tiangen; Campagnolo, Emma M.; Taglietti, Silvia; Scorzoni, Simone; Gianotti, Sara; Martin, Sara; Muenzner, Julia; Muelleder, Michael; Rozenblum, Nir; Rubolino, Carmela; Ben-Yishay, Tal; Laue, Kathrin; Cohen-Sharir, Yael; Vigorito, Ilaria; Nicassio, Francesco; Ruppin, Eytan; Ralser, Markus; Vazquez, Francisca; Santaguida, Stefano; Ben-David, Uri
Feeder-free culture of human pluripotent stem cells drives MDM4-mediated gain of chromosome 1q
STEM CELL REPORTS
IF5.1
2024-08-012
OAAI
Stavish, Dylan; Price, Christopher J.; Gelezauskaite, Gabriele; Alsehli, Haneen; Leonhard, Kimberly A.; Taapken, Seth M.; McIntire, Erik M.; Laing, Owen; James, Bethany M.; Riley, Jack J.; Zerbib, Johanna; Baker, Duncan; Harding, Amy L.; Jestice, Lydia H.; Eleveld, Thomas F.; Gillis, Ad J. M.; Hillenius, Sanne; Looijenga, Leendert H. J.; Gokhale, Paul J.; Ben-David, Uri; Ludwig, Tenneille E.; Barbaric, Ivana
Acute expression of human APOBEC3B in mice results in RNA editing and lethality
GENOME BIOLOGY
IF9.4
2023-11-246
OAAI
Alonso de la Vega, Alicia; Temiz, Nuri Alpay; Tasakis, Rafail; Somogyi, Kalman; Salgueiro, Lorena; Zimmer, Eleni; Ramos, Maria; Diaz-Jimenez, Alberto; Chocarro, Sara; Fernandez-Vaquero, Mirian; Stefanovska, Bojana; Reuveni, Eli; Ben-David, Uri; Stenzinger, Albrecht; Poth, Tanja; Heikenwaelder, Mathias; Papavasiliou, Nina; Harris, Reuben S.; Sotillo, Rocio
Spectrum of Response to Platinum and PARP Inhibitors in Germline BRCA-Associated Pancreatic Cancer in the Clinical and Preclinical Setting
CANCER DISCOVERY
IF33.3
2023-07-1420
OAAI
Stossel, Chani; Raitses-Gurevich, Maria; Atias, Dikla; Beller, Tamar; Gorman, Yulia Glick; Halperin, Sharon; Peer, Eyal; Denroche, Robert E.; Zhang, Amy; Notta, Faiyaz; Wilson, Julie M.; O'Kane, Grainne M.; Talmoud, Elina Haimov; Amison, Nora; Schvimer, Michael; Salpeter, Seth J.; Bar, Vered; Zundelevich, Adi; Tirosh, Itay; Tal, Rotem; Dinstag, Gal; Kinar, Yaron; Eliezer, Yonatan; Ben-David, Uri; Gavert, Nancy S.; Straussman, Ravid; Gallinger, Steven J.; Berger, Raanan; Golan, Talia
Short-term molecular consequences of chromosome mis-segregation for genome stability
NATURE COMMUNICATIONS
IF15.7
2023-03-1130
OAAI
Garribba, Lorenza; De Feudis, Giuseppina; Martis, Valentino; Galli, Martina; Dumont, Marie; Eliezer, Yonatan; Wardenaar, Rene; Ippolito, Marica Rosaria; Iyer, Divya Ramalingam; Tijhuis, Andrea E.; Spierings, Diana C. J.; Schubert, Michael; Taglietti, Silvia; Soriani, Chiara; Gemble, Simon; Basto, Renata; Rhind, Nick; Foijer, Floris; Ben-David, Uri; Fachinetti, Daniele; Doksani, Ylli; Santaguida, Stefano

研究方向

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N
Nissim Benvenisty
H 指数:71论文数:262被引数:2.2万
T
Todd R. Golub
H 指数:176论文数:754被引数:26.6万
R
Rameen Beroukhim
H 指数:149论文数:904被引数:13.6万
G
Gavin Ha
H 指数:90论文数:384被引数:7.3万
J
Johanna Zerbib
H 指数:10论文数:44被引数:666
S
Stefano Santaguida
H 指数:32论文数:122被引数:1.4万
F
Francisca Vázquez
H 指数:76论文数:520被引数:3.3万
Y
Yonatan Eliezer
H 指数:8论文数:67被引数:257
E
Eytan Ruppin
H 指数:98论文数:1,040被引数:3.3万
P
Peter W. Andrews
H 指数:76论文数:372被引数:2.1万