Francisca Vázquez - Publications, H-index & Citations

Francisca Vázquez

broad institute of harvard and massachusetts institute of technology

76H指数

520论文数

3.4W被引数

收录论文 131

发表时间

Editorial Expression of Concern: SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2 编辑意见：对SWI/SNF突变型癌症依赖EZH2的催化和非催化活性的关注

Nature Medicine

IF50

2026-09-18

PREAI

Kimberly H. Kim; Woojin Kim; Thomas P. Howard; Francisca Vazquez; Aviad Tsherniak; Jennifer N. Wu; Weishan Wang; Jeffrey R. Haswell; Loren D. Walensky; William C. Hahn; Stuart H. Orkin; Charles W. M. Roberts

A dependency map enhanced with next-generation 3D cancer models 一张融合了新一代3D癌症模型的药物靶点互作图

Nature

IF48.5

2026-08-05

OAAI

James V. Neiswender; Samuel Maffa; Lisa Brenan; Dina ElHarouni; Yejie Yun; Isabella Boyle; Kirsty Wienand; Haider Inam; Tate Bertea; Ashley Anderson; Megan Wong; Matias Enriquez; Evan Lenz; Beatriz Villafranca; Nora Shanks; Mary Hager; Nia Lloyd; Hannah Shadmany; Sarah J. Wie; Harry Liang; Konnor Yunghans; Xiaomeng Zhang; Lauren Golden; Hannah Harris; Serena Day; Philip Montgomery; Samantha Stokes; Ross M. Giglio; Cynthia Hajal; James R. Whittle; Guadalupe Garcia; Caitlin E. Mills; Mehdi Touat; Kristine Pelton; Hongyu Li; Prem Sai Prabhakar; Sonja Herter; Zoe Hoffmann Kamrat; Dan Gui; Julien Dilly; Chen Khuan Wong; Jimmy A. Guo; Sangita Pal; Yossef Baidi; Ryan Johnston; Daniel D. Brown; Sonam Bhatia; Peter S. Winter; Srivatsan Raghavan; Rameen Beroukhim; Eva Colas; David L. Spector; Adam J. Bass; Peter K. Sorger; Yu Chen; Sarah J. Hill; Steffi Oesterreich; Adrian V. Lee; Himisha Beltran; Jesse S. Boehm; Yuen-Yi Tseng; David E. Root; William C. Hahn; Andrew J. Aguirre; Catarina D. Campbell; Keith L. Ligon; Joshua M. Dempster; Tsukasa Shibue; Francisca Vazquez

Context-dependent synthetic lethality — an emerging precision therapeutic approach 依赖于上下文的合成致死率-一种新兴的精确治疗方法

Nature Reviews Cancer

IF66.8

2026-04-23

PREAI

Liang Chang; Katharin Shaw; Francisca Vazquez; William R. Sellers

Integrative genomic identification of therapeutic targets for pancreatic cancer 整合基因组学鉴定胰腺癌的治疗靶点

Cell Reports

IF6.9

2025-08-21

PREAI

Jimmy A. Guo; Dennis Gong; Kyle Evans; Kazuki Takahashi; Ananya D. Jambhale; Carina Shiau; Patrick Yu; Steven Wang; Wenbo W. Wu; Seema Chugh; Kevin S. Kapner; Julien Dilly; Daniel Zhao; Peter Chen; Eric L. Smith; Joseph D. Mancias; Francisca Vazquez; Harshabad Singh; William L. Hwang; Andrew J. Aguirre

Cancer Dependency Map Past and Present 癌症依赖图谱：过去与现在

ANNUAL REVIEW OF CANCER BIOLOGY

IF6.1

2025-04-11

PREAI

Arafeh, Rand; Shibue, Tsukasa; Vazquez, Francisca; Hahn, William C.

The present and future of the Cancer Dependency Map 癌症依赖图的现在和未来

NATURE REVIEWS CANCER

IF66.8

2024-10-28

PREAI

Arafeh, Rand; Shibue, Tsukasa; Dempster, Joshua M.; Hahn, William C.; Vazquez, Francisca

Increased RNA and Protein Degradation Is Required for Counteracting Transcriptional Burden and Proteotoxic Stress in Human Aneuploid Cells

CANCER DISCOVERY

IF33.3

2024-09-09

OAAI

Ippolito, Marica Rosaria; Zerbib, Johanna; Eliezer, Yonatan; Reuveni, Eli; Vigano, Sonia; De Feudis, Giuseppina; Shulman, Eldad D.; Kadmon, Anouk Savir; Slutsky, Rachel; Chang, Tiangen; Campagnolo, Emma M.; Taglietti, Silvia; Scorzoni, Simone; Gianotti, Sara; Martin, Sara; Muenzner, Julia; Muelleder, Michael; Rozenblum, Nir; Rubolino, Carmela; Ben-Yishay, Tal; Laue, Kathrin; Cohen-Sharir, Yael; Vigorito, Ilaria; Nicassio, Francesco; Ruppin, Eytan; Ralser, Markus; Vazquez, Francisca; Santaguida, Stefano; Ben-David, Uri

A benchmark of computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data (vol 25, 192, 2024)

GENOME BIOLOGY

IF9.4

2024-09-04

OAAI

Vinceti, Alessandro; Iannuzzi, Rafaele M.; Boyle, Isabella; Trastulla, Lucia; Campbell, Catarina D.; Vazquez, Francisca; Dempster, Joshua M.; Iorio, Francesco

RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4

CELL REPORTS

IF6.9

2024-08-01

OAAI

Weinstein, Hannah N. W.; Hu, Kevin; Fish, Lisa; Chen, Yih-An; Allegakoen, Paul; Pham, Julia H.; Hui, Keliana S. F.; Chang, Chih-Hao; Tutar, Meltem; Benitez-Rivera, Lorena; Baco, Maria B.; Song, Hanbing; Giacomelli, Andrew O.; Vazquez, Francisca; Ghandi, Mahmoud; Goodarzi, Hani; Huang, Franklin W.

A benchmark of computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data

GENOME BIOLOGY

IF9.4

2024-07-19

OAAI

Vinceti, Alessandro; Iannuzzi, Raffaele M.; Boyle, Isabella; Trastulla, Lucia; Campbell, Catarina D.; Vazquez, Francisca; Dempster, Joshua M.; Iorio, Francesco

Towards mapping the landscape of cancer vulnerabilities

MOLECULAR CANCER THERAPEUTICS

IF5.5

2024-06-10

PREAI

Vazquez, Francisca

Identifying cancer vulnerabilities associated with changes in chromatin accessibility by simultaneously profiling hundreds of cancer cell lines with ATAC-seq

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Borck, Patricia; Wienand, Kirsty; Duarte, Fabiana; Qin, Alvin; Zhang, Ruochi; Babu, Juliana; Zhang, Simone; Maffa, Samuel; Horlbeck, Max; Shrestha, Rojesh; Dempster, Joshua; Roth, Jennifer; Campbell, Catarina; Buenrostro, Jason; Vazquez, Francisca

CRISPR anchor screens to identify co-vulnerabilities and drug combinations in DepMap

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Serra-Vinardell, Jenny; Posner, Zoe; Cameron, Alison; Chen, Yuqi; Karisani, Negin; De Kegel, Barbara; Dempster, Joshua M.; Aguirre, Andrew J.; Vazquez, Francisca

Aneuploid cells depend on the RAF/MEK/ERK pathway and on RNA degradation for overcoming DNA damage and transcriptional burden

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Ippolito, Marica Rosaria; Zerbib, Johanna Zerbib; Eliezer, Yonatan; Reuveni, Eli; Vigano, Sonia; De Feudis, Giuseppina; Kadmon, Anouk Savir; Ratti, Alice; Martin, Sara; Laue, Kathrin; Cohen-Sharir, Yael; Scorzoni, Simone; Vazquez, Francisca; Ben-David, Uri; Santaguida, Stefano

PELO is a synthetic lethal target in chromosome 9p21-deleted or MSI cancers

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Chan, Edmond M.; Borck, Patricia; Bick, Nolan; Jankovic, Kristina; Boyle, Isabella; Parker-Burns, Lucy; Foster, Kyla; Lau, Anthony; Borah, Ashir; Dempster, Joshua; Vazquez, Francisca

RPL22 is a tumor suppressor in MSI-high cancers and a key splicing regulator of MDM4

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Weinstein, Hannah N.; Hu, Kevin; Fish, Lisa; Chen, Yih-An; Allegakoen, Paul; Hui, Keliana S.; Pham, Julia H.; Baco, Maria B.; Song, Hanbing; Giacomelli, Andrew O.; Vazquez, Francisca; Ghandi, Mahmoud; Goodarzi, Hani; Huang, Franklin W.

Charting ovarian cancer dependencies with patient-derived organoids

CANCER RESEARCH

IF16.6

2024-03-04

PREAI

Anderson, Ashley; Bertea, Tate; Neiswender, James; Brenan, Lisa; Wong, Megan; Simerzin, Alina; Wie, Sarah; Boyle, Isabella; Golden, Lauren; De Kegel, Barbara; Dempster, Josh; Tseng, Yuen-Yi; Root, David; Hill, Sarah; Aguirre, Andrew; Vazquez, Francisca

Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal 当基因敲除是全致死性时，部分CRISPR-Cas9抑制可改善对癌症脆弱性的识别

GENOME BIOLOGY

IF9.4

2023-08-23

OAAI

Krill-Burger, J. Michael; Dempster, Joshua M.; Borah, Ashir A.; Paolella, Brenton R.; Root, David E.; Golub, Todd R.; Boehm, Jesse S.; Hahn, William C.; McFarland, James M.; Vazquez, Francisca; Tsherniak, Aviad

BAF COMPLEX PERTURBATION AS A NOVEL THERAPEUTIC OPPORTUNITY IN H3K27M PEDIATRIC GLIOMA BAF复杂扰动作为H3K27M小儿神经胶质瘤的新治疗机会

NEURO-ONCOLOGY

IF13.4

2023-06-12

OAAI

Panditharatna, Eshini; Marques, Joana G.; Wang, Tingjian; Trissal, Maria; Liu, Ilon; Jiang, Li; Beck, Alexander; Groves, Andrew; Dharia, Neekesh; Hoffman, Samantha; Kugener, Guillaume; Shaw, McKenzie; Hack, Olivia; Dempster, Joshua; Lareau, Caleb; Quezada, Michael; Stanton, Ann-Catherine; Wyatt, Meghan; Kalani, Zohra; Goodale, Amy; Vazquez, Francisca; Piccioni, Federica; Doench, John; Root, David; Anastas, Jamie; Jones, Kristen; Conway, Amy; Stopka, Sylwia; Regan, Michael; Liang, Yu; Seo, Hyuk-Soo; Song, Kijun; Bashyal, Puspalata; Mathewson, Nathan; Dhe-Paganon, Sirano; Suva, Mario L.; Carcaboso, Angel M.; Lavarino, Cinzia; Mora, Jaume; Nguyen, Quang-De; Ligon, Keith L.; Shi, Yang; Agnihotri, Sameer; Agar, Nathalie Y. R.; Stegmaier, Kimberly; Stiles, Charles D.; Monje, Michelle; Golub, Todd R.; Qi, Jun; Filbin, Mariella G.

Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

NATURE CANCER

IF28.5

2023-05-26

PREAI

Simoes, Ricardo de Matos; Shirasaki, Ryosuke; Downey-Kopyscinski, Sondra L.; Matthews, Geoffrey M.; Barwick, Benjamin G.; Gupta, Vikas A.; Dupere-Richer, Daphne; Yamano, Shizuka; Hu, Yiguo; Sheffer, Michal; Dhimolea, Eugen; Dashevsky, Olga; Gandolfi, Sara; Ishiguro, Kazuya; Meyers, Robin M.; Bryan, Jordan G.; Dharia, Neekesh V.; Hengeveld, Paul J.; Bruggenthies, Johanna B.; Tang, Huihui; Aguirre, Andrew J.; Sievers, Quinlan L.; Ebert, Benjamin L.; Glassner, Brian J.; Ott, Christopher J.; Bradner, James E.; Kwiatkowski, Nicholas P.; Auclair, Daniel; Levy, Joan; Keats, Jonathan J.; Groen, Richard W. J.; Gray, Nathanael S.; Culhane, Aedin C.; McFarland, James M.; Dempster, Joshua M.; Licht, Jonathan D.; Boise, Lawrence H.; Hahn, William C.; Vazquez, Francisca; Tsherniak, Aviad; Mitsiades, Constantine S.

研究方向