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A specific microbial consortium enhances Th1 immunity, improves LCMV viral clearance but aggravates LCMV disease pathology in mice 一种特定的微生物共菌群增强了Th1免疫，改善了LCMV病毒清除，但在小鼠中加重了LCMV疾病病理。 Kolland, Daphne; Kuhlmann, Miriam; de Almeida, Gustavo P.; Koehler, Amelie; Arifovic, Anela; von Strempel, Alexandra; Pourjam, Mohsen; Bolsega, Silvia; Wurmser, Christine; Steiger, Katja; Basic, Marijana; Neuhaus, Klaus; Schmidt-Weber, Carsten B.; Stecher, Baerbel; Zehn, Dietmar; Ohnmacht, Caspar 分享 收藏
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Antitumor progenitor exhausted CD8+ T cells are sustained by TCR engagement TCR参与维持抗肿瘤祖细胞耗竭的CD8 T细胞 Lan, Xin; Mi, Tian; Alli, Shanta; Guy, Cliff; Djekidel, Mohamed Nadhir; Liu, Xueyan; Boi, Shannon; Chowdhury, Partha; He, Minghong; Zehn, Dietmar; Feng, Yongqiang; Youngblood, Ben 分享 收藏
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Responses of patients with cancer to mRNA vaccines depend on the time interval between vaccination and last treatment Donhauser, Lara Victoria; de Oliveira, Julia Veloso; Schick, Cordula; Manlik, Wenzel; Styblova, Sabrina; Lutzenberger, Sarah; Aigner, Michael; Philipp, Patrick; Robert, Sebastian; Gandorfer, Beate; Hempel, Dirk; Hempel, Louisa; Zehn, Dietmar 分享 收藏
The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+CD8+T cells in chronic viral infection Marx, Anna-Friederike; Kallert, Sandra M.; Brunner, Tobias M.; Villegas, Jose A.; Geier, Florian; Fixemer, Jonas; Abreu-Mota, Tiago; Reuther, Peter; Bonilla, Weldy V.; Fadejeva, Jelizaveta; Kreutzfeldt, Mario; Wagner, Ingrid; Aparicio-Domingo, Patricia; Scarpellino, Leo; Charmoy, Melanie; Utzschneider, Daniel T.; Hagedorn, Claudia; Lu, Min; Cornille, Karen; Stauffer, Karsten; Kreppel, Florian; Merkler, Doron; Zehn, Dietmar; Held, Werner; Luther, Sanjiv A.; Loehning, Max; Pinschewer, Daniel D. 分享 收藏
A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function Lo, Wan-Lin; Kuhlmann, Miriam; Rizzuto, Gabrielle; Ekiz, H. Atakan; Kolawole, Elizabeth M.; Revelo, Monica P.; Andargachew, Rakieb; Li, Zhongmei; Tsai, Yuan-Li; Marson, Alexander; Evavold, Brian D.; Zehn, Dietmar; Weiss, Arthur 分享 收藏
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development Scherer, Stefanie; Oberle, Susanne G.; Kanev, Kristiyan; Gerullis, Ann-Katrin; Wu, Ming; de Almeida, Gustavo P.; Puleston, Daniel J.; Baixauli, Francesc; Aly, Lilian; Greco, Alessandro; Nizharadze, Tamar; Becker, Nils B.; Hoesslin, Madlaina V.; Donhauser, Lara V.; Berner, Jacqueline; Chu, Talyn; McNamara, Hayley A.; Esencan, Zeynep; Roelli, Patrick; Wurmser, Christine; Kleiter, Ingo; Vehreschild, Maria J. G. T.; Mayer, Christoph A.; Knolle, Percy; Klingenspor, Martin; Fumagalli, Valeria; Iannacone, Matteo; Prlic, Martin; Korn, Thomas; Pearce, Erika L.; Hoefer, Thomas; Schulz, Anna M.; Zehn, Dietmar 分享 收藏
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T cell receptor and IL-2 signaling strength control memory CD8+ T cell functional fitness via chromatin remodeling Chin, Shu Shien; Guillen, Erik; Chorro, Laurent; Achar, Sooraj; Ng, Karina; Oberle, Susanne; Alfei, Francesca; Zehn, Dietmar; Altan-Bonnet, Gregoire; Delahaye, Fabien; Lauvau, Gregoire 分享 收藏
Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches 1型常规树突状细胞在不同的细胞生态区中维持并指导耗竭的T细胞前体的分化 Daehling, Sabrina; Mansilla, Ana Maria; Knoepper, Konrad; Grafen, Anika; Utzschneider, Daniel T.; Ugur, Milas; Whitney, Paul G.; Bachem, Annabell; Arampatzi, Panagiota; Imdahl, Fabian; Kaisho, Tsuneyasu; Zehn, Dietmar; Klauschen, Frederick; Garbi, Natalio; Kallies, Axel; Saliba, Antoine-Emmanuel; Gasteiger, Georg; Bedoui, Sammy; Kastenmueller, Wolfgang 分享 收藏
Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents Koerber, Nina; Priller, Alina; Yazici, Sarah; Bauer, Tanja; Cheng, Cho-Chin; Mijocevic, Hrvoje; Wintersteller, Hannah; Jeske, Samuel; Vogel, Emanuel; Feuerherd, Martin; Tinnefeld, Kathrin; Winter, Christof; Ruland, Juergen; Gerhard, Markus; Haller, Bernhard; Christa, Catharina; Zelger, Otto; Roggendorf, Hedwig; Halle, Martin; Erber, Johanna; Lingor, Paul; Keppler, Oliver; Zehn, Dietmar; Protzer, Ulrike; Knolle, Percy A. 分享 收藏
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