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cyMAEv2: learning robust cell representations in mass cytometry without supervision Kim, Jaesik; Ionita, Matei; Lee, Matthew Eric; Leiby, Jacob S.; Huang, Yidi; Lee, Jonghyun; Nam, Yonghyun; McKeague, Michelle L.; Fang, Victoria; Apostolidis, Sokratis A.; Mathew, Divij; Shwetank; Pattekar, Ajinkya; Rangwala, Zahabia; Huang, Alexander; Bar-Or, Amit; Abramoff, Benjamin; Meyer, Nuala; Painter, Mark M.; Rhee, Rennie; Schuster, Stephen; Maseda, Damian; Greenplate, Allison R.; Wherry, E. John; Kim, Dokyoon 分享 收藏
Divergent ontogeny of tissue resident memory and tissue resident exhausted CD8 T cells underlies distinct functional potential Park, Simone L.; Painter, Mark M.; Manne, Sasikanth; Alcalde, Victor; Sullivan, Matthew; Mathew, Divij; Torres, Leo; Klapholz, Max; Ellebrecht, Christoph; Diab, Ahmed; Giles, Josephine; Wherry, E. John 分享 收藏
Representing immune profiles with self-supervised set representation learning Lee, Matthew Eric; Ionita, Matei; Kim, Jaesik; Lee, Jonghyun; Huang, Yidi; Nam, Yonghyun; McKeague, Michelle L.; Fang, Victoria; Apostolidis, Sokratis A.; Mathew, Divij; Shwetank; Pattekar, Ajinkya; Rangwala, Zahabia; Huang, Alexander; Bar-Or, Amit; Abramoff, Benjamin; Meyer, Nuala; Rhee, Rennie; Schuster, Stephen; Maseda, Damian; Greenplate, Allison R.; Kim, Dokyoon; Wherry, E. John 分享 收藏
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Automated cytometric gating with human-level performance using bivariate segmentation 使用双变量分割实现具有人类水平性能的自动化细胞计量学门控 Chen, Jiong; Ionita, Matei; Feng, Yanbo; Lu, Yinfeng; Orzechowski, Patryk; Garai, Sumita; Hassinger, Kenneth; Bao, Jingxuan; Wen, Junhao; Duong-Tran, Duy; Wagenaar, Joost; Mckeague, Michelle L.; Painter, Mark M.; Mathew, Divij; Pattekar, Ajinkya; Meyer, Nuala J.; Wherry, E. John; Greenplate, Allison R.; Shen, Li 分享 收藏
Recovery of biological signals lost in single-cell batch integration with CellANOVA 用CellANOVA恢复单细胞分批整合中丢失的生物信号 Zhang, Zhaojun; Mathew, Divij; Lim, Tristan L.; Mason, Kaishu; Martinez, Clara Morral; Huang, Sijia; Wherry, E. John; Susztak, Katalin; Minn, Andy J.; Ma, Zongming; Zhang, Nancy R. 分享 收藏
Cytometry masked autoencoder: An accurate and interpretable automated immunophenotyper Kim, Jaesik; Ionita, Matei; Lee, Matthew; Mckeague, Michelle L.; Pattekar, Ajinkya; Painter, Mark M.; Wagenaar, Joost; Truong, Van; Norton, Dylan T.; Mathew, Divij; Nam, Yonghyun; Apostolidis, Sokratis A.; Clendenin, Cynthia; Orzechowski, Patryk; Jung, Sang-Hyuk; Woerner, Jakob; Ittner, Caroline A. G.; Turner, Alexandra P.; Esperanza, Mika; Dunn, Thomas G.; Mangalmurti, Nilam S.; Reilly, John P.; Meyer, Nuala J.; Calfee, Carolyn S.; Liu, Kathleen D.; Matthy, Michael A.; Swigart, Lamorna Brown; Burnham, Ellen L.; Mckeehan, Jeffrey; Gandotra, Sheetal; Russel, Derek W.; Gibbs, Kevin W.; Thomas, Karl W.; Barot, Harsh; Greenplate, Allison R.; Wherry, E. John; Kim, Dokyoon 分享 收藏
Stat5 opposes the transcription factor Tox and rewires exhausted CD8+T cells toward durable effector-like states during chronic antigen exposure Stat5对抗转录因子Tox,并在慢性抗原暴露期间将耗尽的CD8 T细胞重新连接至持久的效应物样状态 Beltra, Jean-Christophe; Abdel-Hakeem, Mohamed S.; Manne, Sasikanth; Zhang, Zhen; Huang, Hua; Kurachi, Makoto; Su, Leon; Picton, Lora; Ngiow, Shin Foong; Muroyama, Yuki; Casella, Valentina; Huang, Yinghui J.; Giles, Josephine R.; Mathew, Divij; Belman, Jonathan; Klapholz, Max; Decaluwe, Helene; Huang, Alexander C.; Berger, Shelley L.; Garcia, K. Christopher; Wherry, E. John 分享 收藏
Deep phenotyping of the lipidomic response in COVID-19 and non-COVID-19 sepsis Meng, Hu; Sengupta, Arjun; Ricciotti, Emanuela; Mrcela, Antonijo; Mathew, Divij; Mazaleuskaya, Liudmila L.; Ghosh, Soumita; Brooks, Thomas G.; Turner, Alexandra P.; Schanoski, Alessa Soares; Lahens, Nicholas F.; Tan, Ai Wen; Woolfork, Ashley; Grant, Greg; Susztak, Katalin; Letizia, Andrew G.; Sealfon, Stuart C.; Wherry, E. John; Laudanski, Krzysztof; Weljie, Aalim M.; Meyer, Nuala J.; FitzGerald, Garret A. 分享 收藏
Modulation of the Immune Response to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination by Nonsteroidal Anti-Inflammatory Drugs Skarke, Carsten; Lordan, Ronan; Barekat, Kayla; Naik, Amruta; Mathew, Divij; Ohtani, Takuya; Greenplate, Allison R.; Grant, Gregory R.; Lahens, Nicholas F.; Gouma, Sigrid; Troisi, Elizabeth; Sengupta, Arjun; Weljie, Aalim M.; Meng, Wenzhao; Prak, Eline T. Luning; Lundgreen, Kendall; Bates, Paul; Meng, Hu; FitzGerald, Garret A. 分享 收藏
Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics 通过时间单细胞转录组学和表观遗传学揭示效应,记忆和耗尽的CD8 T细胞中的共享和独特的生物回路 Giles, Josephine R.; Ngiow, Shin Foong; Manne, Sasikanth; Baxter, Amy E.; Khan, Omar; Wang, Ping; Staupe, Ryan; Abdel-Hakeem, Mohamed S.; Huang, Hua; Mathew, Divij; Painter, Mark M.; Wu, Jennifer E.; Huang, Yinghui Jane; Goel, Rishi R.; Yan, Patrick K.; Karakousis, Giorgos C.; Xu, Xiaowei; Mitchell, Tara C.; Huang, Alexander C.; Wherry, E. John 分享 收藏
SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations Anderson, Elizabeth M.; Li, Shuk Hang; Awofolaju, Moses; Eilola, Theresa; Goodwin, Eileen; Bolton, Marcus J.; Gouma, Sigrid; Manzoni, Tomaz B.; Hicks, Philip; Goel, Rishi R.; Painter, Mark M.; Apostolidis, Sokratis A.; Mathew, Divij; Dunbar, Debora; Fiore, Danielle; Brock, Amanda; Weaver, JoEllen; Millar, John S.; DerOhannessian, Stephanie; Greenplate, Allison R.; Frank, Ian; Rader, Daniel J.; Wherry, E. John; Bates, Paul; Hensley, Scott E. 分享 收藏
Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19 Apostolidis, Sokratis A.; Sarkar, Amrita; Giannini, Heather M.; Goel, Rishi R.; Mathew, Divij; Suzuki, Aae; Baxter, Amy E.; Greenplate, Allison R.; Alanio, Cecile; Abdel-Hakeem, Mohamed; Oldridge, Derek A.; Giles, Josephine R.; Wu, Jennifer E.; Chen, Zeyu; Huang, Yinghui Jane; Belman, Jonathan; Pattekar, Ajinkya; Manne, Sasikanth; Kuthuru, Oliva; Dougherty, Jeanette; Weiderhold, Brittany; Weisman, Ariel R.; Ittner, Caroline A. G.; Gouma, Sigrid; Dunbar, Debora; Frank, Ian; Huang, Alexander C.; Vella, Laura A.; Reilly, John P.; Hensley, Scott E.; Rauova, Lubica; Zhao, Liang; Meyer, Nuala J.; Poncz, Mortimer; Abrams, Charles S.; Wherry, E. John 分享 收藏
Cytomegalovirus Latent Infection is Associated with an Increased Risk of COVID-19-Related Hospitalization Alanio, Cecile; Verma, Anurag; Mathew, Divij; Gouma, Sigrid; Liang, Guanxiang; Dunn, Thomas; Oldridge, Derek A.; Weaver, JoEllen; Kuri-Cervantes, Leticia; Pampena, M. Betina; Betts, Michael R.; Collman, Ronald G.; Bushman, Frederic D.; Meyer, Nuala J.; Hensley, Scott E.; Rader, Daniel; Wherry, E. John 分享 收藏
T CELL INTRINSIC DNA DAMAGE AND REPAIR RESPONSE AS A NOVEL MARKER ASSOCIATED WITH CLINICAL RESPONSE TO PD-1 BLOCKADE Muroyama, Yuki; Manne, Sasikanth; Greenplate, Allison; Mathew, Divij; Oldridge, Derek; Chilukuri, Lakshmi; Xu, Caiyue; Herati, Ramin; Huang, Alexander; Zamarin, Dimitriy; Friedman, Claire; Wherry, E. John 分享 收藏
Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation (vol 22, pg 1008, 2021) Abdel-Hakeem, Mohamed S.; Manne, Sasikanth; Beltra, Jean-Christophe; Stelekati, Erietta; Chen, Zeyu; Nzingha, Kito; Ali, Mohammed-Alkhatim; Johnson, John L.; Giles, Josephine R.; Mathew, Divij; Greenplate, Allison R.; Vahedi, Golnaz; Wherry, E. John 分享 收藏
Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy Apostolidis, Sokratis A.; Kakara, Mihir; Painter, Mark M.; Goel, Rishi R.; Mathew, Divij; Lenzi, Kerry; Rezk, Ayman; Patterson, Kristina R.; Espinoza, Diego A.; Kadri, Jessy C.; Markowitz, Daniel M.; Markowitz, Clyde E.; Mexhitaj, Ina; Jacobs, Dina; Babb, Allison; Betts, Michael R.; Prak, Eline T. Luning; Weiskopf, Daniela; Grifoni, Alba; Lundgreen, Kendall A.; Gouma, Sigrid; Sette, Alessandro; Bates, Paul; Hensley, Scott E.; Greenplate, Allison R.; Wherry, E. John; Li, Rui; Bar-Or, Amit 分享 收藏
Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination Painter, Mark M.; Mathew, Divij; Goel, Rishi R.; Apostolidis, Sokratis A.; Pattekar, Ajinkya; Kuthuru, Oliva; Baxter, Amy E.; Herati, Ramin S.; Oldridge, Derek A.; Gouma, Sigrid; Hicks, Philip; Dysinger, Sarah; Lundgreen, Kendall A.; Kuri-Cervantes, Leticia; Adamski, Sharon; Hicks, Amanda; Korte, Scott; Giles, Josephine R.; Weirick, Madison E.; McAllister, Christopher M.; Dougherty, Jeanette; Long, Sherea; D'Andrea, Kurt; Hamilton, Jacob T.; Betts, Michael R.; Bates, Paul; Hensley, Scott E.; Grifoni, Alba; Weiskopf, Daniela; Sette, Alessandro; Greenplate, Allison R.; Wherry, E. John 分享 收藏