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S

Siddhartha Kar

University of Bristol
H指数:42
被引数:8,038

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Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer

398,238名女性的全基因组关联研究揭示了七个与高级别浆液性卵巢癌相关的位点

npj Genomic Medicine
IF4.8
2025-11-200
OAAI
Daniel R. Barnes; Jonathan P. Tyrer; Joe Dennis; Goska Leslie; Manjeet K. Bolla; Michael Lush; Amber M. Aeilts; Kristiina Aittomäki; Nadine Andrieu; Irene L. Andrulis; Hoda Anton-Culver; Adalgeir Arason; Banu K. Arun; Judith Balmaña; Elisa V. Bandera; Rosa B. Barkardottir; Lieke P. V. Berger; Amy Berrington de Gonzalez; Pascaline Berthet; Katarzyna Białkowska; Line Bjørge; Amie M. Blanco; Marinus J. Blok; Kristie A. Bobolis; Natalia V. Bogdanova; James D. Brenton; Henriett Butz; Saundra S. Buys; Maria A. Caligo; Ian Campbell; Carmen Castillo; Kathleen B. M. Claes; Sarah V. Colonna; Linda S. Cook; Mary B. Daly; Agnieszka Dansonka-Mieszkowska; Miguel de la Hoya; Anna deFazio; Allison DePersia; Yuan Chun Ding; Jennifer A. Doherty; Susan M. Domchek; Thilo Dörk; Zakaria Einbeigi; Christoph Engel; D. Gareth Evans; Lenka Foretova; Renée T. Fortner; Florentia Fostira; Maria Cristina Foti; Eitan Friedman; Megan N. Frone; Patricia A. Ganz; Aleksandra Gentry-Maharaj; Gord Glendon; Andrew K. Godwin; Anna González-Neira; Mark H. Greene; Jacek Gronwald; Aliana Guerrieri-Gonzaga; Ute Hamann; Thomas V. O. Hansen; Holly R. Harris; Jan Hauke; Florian Heitz; Frans B. L. Hogervorst; Maartje J. Hooning; John L. Hopper; Chad D. Huff; David G. Huntsman; Evgeny N. Imyanitov; Louise Izatt; Anna Jakubowska; Paul A. James; Ramunas Janavicius; Esther M. John; Siddhartha Kar; Beth Y. Karlan; Catherine J. Kennedy; Lambertus A.L.M. Kiemeney; Irene Konstantopoulou; Jolanta Kupryjanczyk; Yael Laitman; Ofer Lavie; Kate Lawrenson; Jenny Lester; Fabienne Lesueur; Carlos Lopez-Pleguezuelos; Phuong L. Mai; Siranoush Manoukian; Taymaa May; Iain A. McNeish; Usha Menon; Roger L. Milne; Francesmary Modugno; Jennifer M. Mongiovi; Marco Montagna; Kirsten B. Moysich; Susan L. Neuhausen; Finn C. Nielsen; Catherine Noguès; Edit Oláh; Olufunmilayo I. Olopade; Ana Osorio; Laura Papi; Harsh Pathak; Celeste L. Pearce; Inge S. Pedersen; Ana Peixoto; Tanja Pejovic; Pei-Chen Peng; Beth N. Peshkin; Paolo Peterlongo; C. Bethan Powell; Darya Prokofyeva; Miquel Angel Pujana; Paolo Radice; Muhammad U. Rashid; Gad Rennert; George Richenberg; Dale P. Sandler; Naoko Sasamoto; Veronica W. Setiawan; Priyanka Sharma; Weiva Sieh; Christian F. Singer; Katie Snape; Anna P. Sokolenko; Penny Soucy; Melissa C. Southey; Dominique Stoppa-Lyonnet; Rebecca Sutphen; Christian Sutter; Yen Y. Tan; Manuel R. Teixeira; Kathryn L. Terry; Liv Cecilie V. Thomsen; Marc Tischkowitz; Amanda E. Toland; Toon Van Gorp; Ana Vega; Digna R. Velez Edwards; Penelope M. Webb; Jeffrey N. Weitzel; Nicolas Wentzensen; Alice S. Whittemore; Stacey J. Winham; Anna H. Wu; Siddhartha Yadav; Yao Yu; Argyrios Ziogas; Andrew Berchuck; Fergus J. Couch; Ellen L. Goode; Marc T. Goodman; Alvaro N. Monteiro; Kenneth Offit; Susan J. Ramus; Harvey A. Risch; Joellen M. Schildkraut; Mads Thomassen; Jacques Simard; Douglas F. Easton; Michelle R. Jones; Georgia Chenevix-Trench; Simon A. Gayther; Antonis C. Antoniou; Paul D. P. Pharoah
Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis

端粒损耗成为衰老造血和白血病发生过程中克隆选择的一种机制。

Nature Genetics
IF0
2025-08-280
OAAI
Matthew A. McLoughlin; Sruthi Cheloor Kovilakam; William G. Dunn; Muxin Gu; Jake Tobin; Yash Pershad; Nicholas Williams; Daniel Leongamornlert; Kevin Dawson; Laura Bond; Ludovica Marando; Sean Wen; Rachael Wilson; Giampiero Valenzano; Vasiliki Symeonidou; Justyna Rak; Aristi Damaskou; Malgorzata Gozdecka; Xiaoxuan Liu; Clea Barcena; Josep Nomdedeu; Paul Costeas; Ioannis D. Dimitriou; Edoardo Fiorillo; Valeria Orrù; Jose Guilherme de Almeida; Thomas McKerrell; Matthew Cullen; Irina Mohorianu; Theodora Foukaneli; Alan J. Warren; Chi Wong; George Follows; Anna L. Godfrey; Emma Gudgin; Francesco Cucca; Eoin McKinney; E. Joanna Baxter; Moritz Gerstung; Jonathan Mitchell; Daniel Wiseman; Alexander G. Bick; Margarete Fabre; Pedro M. Quiros; Jyoti Nangalia; Siddhartha Kar; George S. Vassiliou
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions

整合多组学分析以确定卵巢癌风险区域的遗传和功能机制

AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2024-06-016
PRE
Dareng, Eileen O.; Coetzee, Simon G.; Tyrer, Jonathan P.; Peng, Pei-Chen; Rosenow, Will; Chen, Stephanie; Davis, Brian D.; Dezem, Felipe Segato; Seo, Ji-Heui; Nameki, Robbin; Reyes, Alberto L.; Aben, Katja K. H.; Anton-Culver, Hoda; Antonenkova, Natalia N.; Aravantinos, Gerasimos; Bandera, Elisa V.; Freeman, Laura E. Beane; Beckmann, Matthias W.; Beeghly-Fadiel, Alicia; Benitez, Javier; Bernardini, Marcus Q.; Bjorge, Line; Black, Amanda; Bogdanova, Natalia V.; Bolton, Kelly L.; Brenton, James D.; Budzilowska, Agnieszka; Butzow, Ralf; Cai, Hui; Campbell, Ian; Cannioto, Rikki; Chang-Claude, Jenny; Chanock, Stephen J.; Chen, Kexin; Chenevix-Trench, Georgia; Chiew, Yoke-Eng; Cook, Linda S.; DeFazio, Anna; Dennis, Joe; Doherty, Jennifer A.; Doerk, Thilo; du Bois, Andreas; Duerst, Matthias; Eccles, Diana M.; Ene, Gabrielle; Fasching, Peter A.; Flanagan, James M.; Fortner, Renee T.; Fostira, Florentia; Gentry-Maharaj, Aleksandra; Giles, Graham G.; Goodman, Marc T.; Gronwald, Jacek; Haiman, Christopher A.; Hakansson, Niclas; Heitz, Florian; Hildebrandt, Michelle A. T.; Hogdall, Estrid; Hogdall, Claus K.; Huang, Ruea-Yea; Jensen, Allan; Jones, Michael E.; Kang, Daehee; Karlan, Beth Y.; Karnezis, Anthony N.; Kelemen, Linda E.; Kennedy, Catherine J.; Khusnutdinova, Elza K.; Kiemeney, Lambertus A.; Kjaer, Susanne K.; Kupryjanczyk, Jolanta; Labrie, Marilyne; Lambrechts, Diether; Larson, Melissa C.; Le, Nhu D.; Lester, Jenny; Li, Lian; Lubinski, Jan; Lush, Michael; Marks, Jeffrey R.; Matsuo, Keitaro; May, Taymaa; McLaughlin, John R.; McNeish, Iain A.; Menon, Usha; Missmer, Stacey; Modugno, Francesmary; Moffitt, Melissa; Monteiro, Alvaro N.; Moysich, Kirsten B.; Narod, Steven A.; Nguyen-Dumont, Tu; Odunsi, Kunle; Olsson, Hakan; Onland-Moret, N. Charlotte; Park, Sue K.; Pejovic, Tanja; Permuth, Jennifer B.; Piskorz, Anna; Prokofyeva, Darya; Riggan, Marjorie J.; Risch, Harvey A.; Rodriguez-Antona, Cristina; Rossing, Mary Anne; Sandler, Dale P.; Setiawan, V. Wendy; Shan, Kang; Song, Honglin; Southey, Melissa C.; Steed, Helen; Sutphen, Rebecca; Swerdlow, Anthony J.; Teo, Soo Hwang; Terry, Kathryn L.; Thompson, Pamela J.; Thomsen, Liv Cecilie Vestrheim; Titus, Linda; Trabert, Britton; Travis, Ruth; Tworoger, Shelley S.; Valen, Ellen; Van Nieuwenhuysen, Els; Edwards, Digna Velez; Vierkant, Robert A.; Webb, Penelope M.; Weinberg, Clarice R.; Weise, Rayna Matsuno; Wentzensen, Nicolas; White, Emily; Winham, Stacey J.; Wolk, Alicja; Woo, Yin-Ling; Wu, Anna H.; Yan, Li; Yannoukakos, Drakoulis; Zeinomar, Nur; Zheng, Wei; Ziogas, Argyrios; Berchuck, Andrew; Goode, Ellen L.; Huntsman, David G.; Pearce, Celeste L.; Ramus, Susan J.; Sellers, Thomas A.; Freedman, Matthew L.; Lawrenson, Kate; Schildkraut, Joellen M.; Hazelett, Dennis; Plummer, Jasmine T.; Kar, Siddhartha; Jones, Michelle R.; Pharoah, Paul D. P.; Gayther, Simon A.
A genome-wide association study of neutrophil count in individuals associated to an African continental ancestry group facilitates studies of malaria pathogenesis

与非洲大陆血统组相关的个体中性粒细胞计数的全基因组关联研究促进了疟疾发病机理的研究

HUMAN GENOMICS
IF4.3
2024-03-151
OAAI
Constantinescu, Andrei-Emil; Hughes, David A.; Bull, Caroline J.; Fleming, Kathryn; Mitchell, Ruth E.; Zheng, Jie; Kar, Siddhartha; Timpson, Nicholas J.; Amulic, Borko; Vincent, Emma E.
Multiparameter prediction of myeloid neoplasia risk

髓系肿瘤风险的多参数预测

NATURE GENETICS
IF31.8
2023-08-2437
OAAI
Gu, Muxin; Kovilakam, Sruthi Cheloor; Dunn, William G.; Marando, Ludovica; Barcena, Clea; Mohorianu, Irina; Smith, Alexandra; Kar, Siddhartha P.; Fabre, Margarete A.; Gerstung, Moritz; Cargo, Catherine A.; Malcovati, Luca; Quiros, Pedro M.; Vassiliou, George S.
Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions

全基因组分析表征癌症之间的共享遗传力，并确定新的癌症易感区域

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
2023-03-177
PRE
Lindstrom, Sara; Wang, Lu; Feng, Helian; Majumdar, Arunabha; Huo, Sijia; Macdonald, James; Harrison, Tabitha; Turman, Constance; Chen, Hongjie; Mancuso, Nicholas; Bammler, Theo; Gallinger, Steve; Gruber, Stephen B.; Gunter, Marc J.; Le Marchand, Loic; Moreno, Victor; Offit, Kenneth; De Vivo, Immaculata; O'Mara, Tracy A.; Spurdle, Amanda B.; Tomlinson, Ian; Fitzgerald, Rebecca; Gharahkhani, Puya; Gockel, Ines; Jankowski, Janusz; Macgregor, Stuart; Schumacher, Johannes; Barnholtz-Sloan, Jill; Bondy, Melissa L.; Houlston, Richard S.; Jenkins, Robert B.; Melin, Beatrice; Wrensch, Margaret; Brennan, Paul; Christiani, David C.; Johansson, Mattias; Mckay, James; Aldrich, Melinda C.; Amos, Christopher, I; Landi, Maria Teresa; Tardon, Adonina; Bishop, D. Timothy; Demenais, Florence; Goldstein, Alisa M.; Iles, Mark M.; Kanetsky, Peter A.; Law, Matthew H.; Amundadottir, Laufey T.; Stolzenberg-Solomon, Rachael; Wolpin, Brian M.; Klein, Alison; Petersen, Gloria; Risch, Harvey; Chanock, Stephen J.; Purdue, Mark P.; Scelo, Ghislaine; Pharoah, Paul; Kar, Siddhartha; Hung, Rayjean J.; Pasaniuc, Bogdan; Kraft, Peter

研究方向

暂未获取到该数据
P
Paul D.P. Pharoah
H 指数:150论文数:1,771被引数:9.6万
G
Georgia Chenevix‐Trench
H 指数:115论文数:997被引数:7.0万
D
Diether Lambrechts
H 指数:122论文数:1,318被引数:6.9万
J
Jonathan P. Tyrer
H 指数:73论文数:469被引数:3.6万
H
Hoda Anton‐Culver
H 指数:111论文数:885被引数:5.2万
M
Melissa C. Southey
H 指数:121论文数:1,251被引数:6.7万
S
Simon A. Gayther
H 指数:85论文数:820被引数:3.1万
J
Jenny Chang‐Claude
H 指数:128论文数:1,505被引数:6.9万
G
Graham G. Giles
H 指数:164论文数:2,399被引数:12.2万
J
Jacques Simard
H 指数:98论文数:715被引数:4.5万