David A. Guertin - Publications, H-index & Citations

David A. Guertin

UMass Chan Medical School

43H指数

91论文数

2.7W被引数

收录论文 56

发表时间

Brown adipose tissue remains hot 棕色脂肪组织仍然很热

Nature Reviews Endocrinology

IF31.8

2025-12-16

PREAI

Benjamin E. Clayton; David A. Guertin

Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress

NATURE METABOLISM

IF20.8

2024-10-14

PREAI

Korobkina, Ekaterina D.; Calejman, Camila Martinez; Haley, John A.; Kelly, Miranda E.; Li, Huawei; Gaughan, Maria; Chen, Qingbo; Pepper, Hannah L.; Ahmad, Hafsah; Boucher, Alexander; Fluharty, Shelagh M.; Lin, Te-Yueh; Lotun, Anoushka; Peura, Jessica; Trefely, Sophie; Green, Courtney R.; Vo, Paula; Semenkovich, Clay F.; Pitarresi, Jason R.; Spinelli, Jessica B.; Aydemir, Ozkan; Metallo, Christian M.; Lynes, Matthew D.; Jang, Cholsoon; Snyder, Nathaniel W.; Wellen, Kathryn E.; Guertin, David A.

Tumor-secreted PTHrP facilitates pancreatic cancer cachexia by regulation of de novo lipogenesis pathway

CANCER RESEARCH

IF16.6

2024-09-15

PREAI

Bhalerao, Nikita; Peura, Jessica; Ogoti, Yamini; Johnson, Calvin; Chen, Qingbo; Korobkina, Ekaterina; Keller, Faith; Wengyn, Maximillan; Norgard, Robert; Kremmer, Richard; Watson, Emma; Ruscetti, Marcus; Guertin, David; Pitarresi, Jason R.

Adipose glutaminolysis resurfaces in metabolic disease

NATURE METABOLISM

IF20.8

2024-07-15

PREAI

Haley, John A.; Guertin, David A.

Functional genomic screens with death rate analyses reveal mechanisms of drug action 具有死亡率分析的功能基因组筛选揭示了药物作用机制

NATURE CHEMICAL BIOLOGY

IF13.7

2024-03-13

PREAI

Honeywell, Megan E.; Isidor, Marie S.; Harper, Nicholas W.; Fontana, Rachel E.; Birdsall, Gavin A.; Cruz-Gordillo, Peter; Porto, Sydney A.; Jerome, Madison; Fraser, Cameron S.; Sarosiek, Kristopher A.; Guertin, David A.; Spinelli, Jessica B.; Lee, Michael J.

Abstract PR09: Pancreatic cancer cachexia is mediated by tumor-derived PTHrP

CANCER RESEARCH

IF16.6

2024-01-16

PREAI

Ogoti, Yamini; Peura, Jessica; Johnson, Calvin; Korobkina, Ekaterina; Wengyn, Maximilian; Norgard, Robert J.; Kremer, Richard; Guertin, David A.; Pitarresi, Jason R.

A new era of understanding in vivo metabolic flux in thermogenic adipocytes

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2023-12-01

OAAI

Haley, John A.; Jang, Cholsoon; Guertin, David A.

Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis

NATURE METABOLISM

IF20.8

2023-06-19

PREAI

Park, Grace; Haley, John A.; Le, Johnny; Jung, Su Myung; Fitzgibbons, Timothy P.; Korobkina, Ekaterina D.; Li, Huawei; Fluharty, Shelagh M.; Chen, Qingbo; Spinelli, Jessica B.; Trivedi, Chinmay M.; Jang, Cholsoon; Guertin, David A.

Initiation of cytokinesis is controlled through multiple modes of regulation of the Sid2p-Mob1p kinase complex

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Hou, MC; Guertin, DA; McCollum, D

Acetyl-CoA metabolism in cancer 癌症中的乙酰辅酶a代谢

NATURE REVIEWS CANCER

IF66.8

2023-01-19

OAAI

Guertin, David A.; Wellen, Kathryn E.

A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis

NATURE COMMUNICATIONS

IF15.7

2022-12-10

OAAI

Chen, Qingbo; Huang, Lei; Pan, Dongning; Hu, Kai; Li, Rui; Friedline, Randall H.; Kim, Jason K.; Zhu, Lihua Julie; Guertin, David A.; Wang, Yong-Xu

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-10-01

OAAI

Luciano, Amelia K.; Korobkina, Ekaterina D.; Lyons, Scott P.; Haley, John A.; Fluharty, Shelagh M.; Jung, Su Myung; Kettenbach, Arminja N.; Guertin, David A.

Integrating adipocyte insulin signaling and metabolism in the multi-omics era

TRENDS IN BIOCHEMICAL SCIENCES

IF11

2022-06-01

OAAI

Calejman, C. Martinez; Doxsey, W. G.; Fazakerley, D. J.; Guertin, D. A.

In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate

CELL REPORTS

IF6.9

2021-07-01

OAAI

Jung, Su Myung; Doxsey, Will G.; Le, Johnny; Haley, John A.; Mazuecos, Lorena; Luciano, Amelia K.; Li, Huawei; Jang, Cholsoon; Guertin, David A.

The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development

CELL REPORTS

IF6.9

2020-10-01

OAAI

Hsiao, Wen-Yu; Jung, Su Myung; Tang, Yuefeng; Haley, John A.; Li, Rui; Li, Huawei; Calejman, Camila Martinez; Sanchez-Gurmaches, Joan; Hung, Chien-Min; Luciano, Amelia K.; DeMambro, Victoria; Wellen, Kathryn E.; Rosen, Clifford J.; Zhu, Lihua Julie; Guertin, David A.

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis (vol 11, 575, 2020)

NATURE COMMUNICATIONS

IF15.7

2020-09-08

OAAI

Calejman, C. Martinez; Trefely, S.; Entwisle, S. W.; Luciano, A.; Jung, S. M.; Hsiao, W.; Torres, A.; Hung, C. M.; Li, H.; Snyder, N. W.; Villen, J.; Wellen, K. E.; Guertin, D. A.

Proteome and Phosphoproteome Analysis of Brown Adipocytes Reveals That RICTOR Loss Dampens Global Insulin/AKT Signaling

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2020-07-01

OAAI

Entwisle, Samuel W.; Calejman, Camila Martinez; Valente, Anthony S.; Lawrence, Robert T.; Hung, Chien-Min; Guertin, David A.; Villen, Judit

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis

NATURE COMMUNICATIONS

IF15.7

2020-01-29

OAAI

Calejman, C. Martinez; Trefely, S.; Entwisle, S. W.; Luciano, A.; Jung, S. M.; Hsiao, W.; Torres, A.; Hung, C. M.; Li, H.; Snyder, N. W.; Villen, J.; Wellen, K. E.; Guertin, D. A.

De Novo Lipogenesis as a Source of Second Messengers in Adipocytes

CURRENT DIABETES REPORTS

IF6.4

2019-11-20

OAAI

Hsiao, Wen-Yu; Guertin, David A.

Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1

MOLECULAR CELL

IF16.6

2019-08-01

OAAI

Jung, Su Myung; Hung, Chien-Min; Hildebrand, Samuel R.; Sanchez-Gurmaches, Joan; Martinez-Pastor, Barbara; Gengatharan, Jivani M.; Wallace, Martina; Mukhopadhyay, Dimpi; Calejman, Camila Martinez; Luciano, Amelia K.; Hsiao, Wen-Yu; Tang, Yuefeng; Li, Huawei; Daniels, Danette L.; Mostoslaysky, Raul; Metallo, Christian M.; Guertin, David A.

研究方向