未登录 The association between telomere length and expression of DNA repair genes as a biological trace of cumulative lifetime stress 端粒长度与DNA修复基因表达之间的关联作为累积终生压力的生物痕迹 Keppler, Hannah; Mavioglu, R. Nehir; Behnke, Alexander; Gola, Hannah; Hitzler, Melissa; Fieres, Judy; Christmann, Markus; Burkle, Alexander; Moreno-Villanueva, Maria; Kolassa, Iris-Tatjana; Mack, Matthias 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Molecular dosimetry of estragole and 1′-hydroxyestragole-induced DNA adduct formation, clastogenicity and cytotoxicity in human liver cell models estragole和1′-hydroxyestragole诱导的DNA加合物形成、断裂基因毒性及细胞毒性的分子剂量学，在人类肝细胞模型中 Ackermann, G.; Peil, M.; Quarz, C.; Schmidt, A.; Halaczkiewicz, M.; Thomas, A. D.; Stegmueller, S.; Richling, E.; Manolikakes, G.; Christmann, M.; Kuepper, J. H.; Schrenk, D.; Fahrer, J. 分享 收藏
Therapy-induced senescence of glioblastoma cells is determined by the p21CIP1-CDK1/2 axis and does not require activation of DREAM 胶质瘤细胞的治疗性衰老由p21CIP1-CDK1/2轴决定，并且不需要DREAM的激活。 Schwarzenbach, Christian; Rinke, Justus; Vilar, Juliana B.; Sallbach, Jason; Tatsch, Larissa; Schmidt, Ariane; Schoeneis, Anna; Rasenberger, Birgit; Kaina, Bernd; Tomicic, Maja T.; Christmann, Markus 分享 收藏
The p21CIP1-CDK4-DREAM axis is a master regulator of genotoxic stress-induced cellular senescence Schmidt, Ariane; Allmann, Sebastian; Schwarzenbach, Christian; Snyder, Petra; Chen, Jia-Xuan; Nagel, Georg; Schoeneis, Anna; Rasenberger, Birgit; Beli, Petra; Loewer, Alexander; Hofmann, Thomas G.; Tomicic, Maja T.; Christmann, Markus 分享 收藏
p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol Carlsson, Max J.; Vollmer, Anastasia S.; Demuth, Philipp; Heylmann, Daniel; Reich, Diana; Quarz, Caroline; Rasenberger, Birgit; Nikolova, Teodora; Hofmann, Thomas G.; Christmann, Markus; Fuhlbrueck, Julia A.; Stegmueller, Simone; Richling, Elke; Cartus, Alexander T.; Fahrer, Jorg 分享 收藏
分享 收藏
分享 收藏
Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells Beyer, Mandy; Henninger, Sven J.; Haehnel, Patricia S.; Mustafa, Al-Hassan M.; Gurdal, Ece; Schubert, Bastian; Christmann, Markus; Sellmer, Andreas; Mahboobi, Siavosh; Drube, Sebastian; Sippl, Wolfgang; Kindler, Thomas; Kraemer, Oliver H. 分享 收藏
Repair of O6-carboxymethylguanine adducts by O6-methylguanine-DNA methyltransferase in human colon epithelial cells Kostka, Tina; Empl, Michael T.; Seiwert, Nina; Geisen, Susanne M.; Hoffmann, Pascal; Adam, Janine; Seeger, Bettina; Shay, Jerry W.; Christmann, Markus; Sturla, Shana J.; Fahrer, Joerg; Steinberg, Pablo 分享 收藏
Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination Reich, Thomas R.; Schwarzenbach, Christian; Vilar, Juliana Brandstetter; Unger, Sven; Muehlhaeusler, Fabian; Nikolova, Teodora; Poplawski, Alicia; Baymaz, H. Irem; Beli, Petra; Christmann, Markus; Tomicic, Maja T. 分享 收藏
分享 收藏
分享 收藏
Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation Neitzel, Carina; Seiwert, Nina; Goeder, Anja; Diehl, Erika; Weber, Carina; Nagel, Georg; Stroh, Svenja; Rasenberger, Birgit; Christmann, Markus; Fahrer, Joerg 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Temozolomide Induces Senescence and Repression of DNA Repair Pathways in Glioblastoma Cells via Activation of ATR-CHK1, p21, and NF-κB Aasland, Dorthe; Goetzinger, Laura; Hauck, Laura; Berte, Nancy; Meyer, Jessica; Effenberger, Melanie; Schneider, Simon; Reuber, Emelie E.; Roos, Wynand P.; Tomicic, Maja T.; Kaina, Bernd; Christmann, Markus 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
