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E

Erich Gulbins

university of duisburg-essen
H指数:97
被引数:3.5万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Endothelial NLRP3 pyroptotic as a trigger for blood brain barrier disruption and neurotoxic Astrogenesis in chronic intermittent hypoxia

内皮细胞NLRP3焦亡作为慢性间歇性缺氧下血脑屏障破坏和神经毒性星形胶质细胞生成的触发因素

Biochemical Pharmacology
IF5.6
2026-09-100
OAAI
null Zihan; Yuqi Yuan; null Xiaoxin; Simin Zhu; Jiayi Yang; Rui Lu; Zitong Wang; Chendi Lu; null Yushan; Yani Feng; Jiayi Du; null Chutong; null Chenxi; null Chanchan; null Haiqin; null Weichao; Erich Gulbins; Xiaoyong Ren; Yewen Shi
Inhaled sphingosine reduces bronchial Pseudomonas aeruginosa burden during porcine ex vivo lung perfusion and shows tissue delivery in explanted human lungs

吸入鞘氨醇可降低离体猪肺灌注期间支气管铜绿假单胞菌负荷，并在切除的人肺中显示出组织递送

Scientific Reports
IF3.9
2026-08-060
OA
Yongjie Liu; Fabian Schumacher; Yuqing Wu; Lydia Leukers; Kristin Schimank; Omar Abou-Issa; Christian Taube; Andreas Wissmann; Nikolaus Pizanis; Burkhard Kleuser; Achim Koch; Erich Gulbins; Markus Kamler
Tumor-specific targeting of a mitochondrial Kv1.3 channel inhibitor through conjugation to gastrin/cholecystokinin B receptor ligand strongly reduces pancreatic ductal adenocarcinoma in orthotopic models

通过将线粒体Kv1.3通道抑制剂与胃泌素/胆囊收缩素B受体配体缀合进行肿瘤特异性靶向，可显著降低正位胰腺导管腺癌模型中的肿瘤负荷。

Pharmacological Research
IF10.5
2026-02-200
OAAI
Sofia Parrasia; Carlotta Paoli; Tatiana Varanita; Valentina Brillo; Mostafa A.L Abdel-Salam; Alberto Ongaro; Claudia Hornisch; Beatrice Angi; Magdalena Bachmann; Filippo Bergamin; Vincenzo Corbo; Elena Fiorini; Andrea Rossa; Giovanna Bossio; Erich Gulbins; Alessandro Carrer; Mario Zoratti; Andrea Mattarei; Paolo Ruzza; Lucia Biasutto
Acid ceramidase regulates CD8+ T-cell exhaustion via type I interferon-mediated upregulation of PD-L1

酸神经酰胺酶通过I型干扰素介导的PD-L1上调来调节CD8+ T细胞耗竭

Frontiers in Immunology
IF5.9
2025-12-090
OAAI
Zhongwen Hu†‡; Hossam Abdelrahman‡; Abdelrahman Elwy‡; Fei Kuang†‡; Swati Dhiman; Shafaqat Ali†; Marcel Marson†‡; Lisa Holnsteiner; Thamer A. Hamdan†; Justa Friebus-Kardash; Elisa Wiebeck; Wiebke Hansen; Stefanie Scheu†; Erich Gulbins; Philipp Alexander Lang; Karl Sebastian Lang; Judith Lang
Deactivation of ceramide de novo synthesis induces cerebral angiogenesis and microvascular remodeling post-ischemia/reperfusion in mice via mechanisms not predominated by extracellular vesicles

鞘氨醇二磷酸脱氢酶从头合成失活通过非外泌体主导的机制，诱导小鼠缺血/再灌注后的脑血管生成和微血管重塑。

Journal of Cerebral Blood Flow & Metabolism
IF0
2025-11-030
OA
Ayan Mohamud Yusuf; Tanja Hussner; AnRan Li; Nina Hagemann; Thorsten Hornemann; Tobias Tertel; Ulf Brockmeier; Fabian Schumacher; Burkhard Kleuser; Bernd Giebel; Matthias Gunzer; Erich Gulbins; Dirk M Hermann
Amitriptyline potently neutralizes distinct SARS-CoV-2 variants including D614G; Omicron BA.5; and Omicron XBB.1

阿米替林强力中和不同的SARS-CoV-2变体，包括D614G；奥密克戎BA.5；和奥密克戎XBB.1

Frontiers in Microbiology
IF4.5
2025-08-040
OA
Isabel Zydek†; Laura Thümmler†; Nadine Beckmann†; Carolin Sehl; Matthias Soddemann; Rabea Grüneberg; Carina Elsner; Markus Kamler; Ulf Dittmer; Oliver Witzke; Stephanie Kadow; Erich Gulbins; Katrin Anne Becker; Adalbert Krawczyk
Amitriptyline inhibits Plasmodium development in infected red blood cells by modulating sphingolipid metabolism and glucose uptake

阿米替林通过调节鞘脂代谢和葡萄糖摄取，抑制感染红细胞中疟原虫的发育

Biomedicine & Pharmacotherapy
IF7.5
2025-07-080
PRE
Matthias Hose; Anne Ninnemann; Hanna Abberger; Fabian Schumacher; Eyad Naser; Leopold Purkart; Francois Korbmacher; Luiza Martins Nascentes Melo; Nadine Beckmann; Vivien Blietschau; Julia Falkenstein; Burkhard Kleuser; Alpaslan Tasdogan; Erich Gulbins; Alexander Carpinteiro; Robert Klopfleisch; Jan Buer; Astrid M. Westendorf; Kai Matuschewski; Wiebke Hansen
BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Kv1.3钾通道的基于BioID的完整细胞相互作用组可识别Kv1.3 STAT3-p53的细胞信号传导途径

SCIENCE ADVANCES
IF12.5
2024-09-060
OAAI
Prosdocimi, Elena; Carpanese, Veronica; Todesca, Luca Matteo; Varanita, Tatiana; Bachmann, Magdalena; Festa, Margherita; Bonesso, Daniele; Perez-Verdaguer, Mireia; Carrer, Andrea; Velle, Angelo; Peruzzo, Roberta; Muccioli, Silvia; Doni, Davide; Leanza, Luigi; Costantini, Paola; Stein, Frank; Rettel, Mandy; Felipe, Antonio; Edwards, Michael J.; Gulbins, Erich; Cendron, Laura; Romualdi, Chiara; Checchetto, Vanessa; Szabo, Ildiko

研究方向

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J
Johannes Kornhuber
H 指数:106论文数:1,516被引数:5.9万
K
Katrin Anne Becker
H 指数:40论文数:118被引数:5,249
H
Heike Grassmé
H 指数:44论文数:121被引数:8,039
F
Florian Läng
H 指数:128论文数:1,968被引数:9.0万
B
Burkhard Kleuser
H 指数:55论文数:342被引数:1.2万
I
Ildikò Szabó
H 指数:73论文数:528被引数:2.2万
A
Alexander Carpinteiro
H 指数:32论文数:128被引数:2,802
M
Mario Zoratti
H 指数:61论文数:190被引数:1.3万
F
Fabian Schumacher
H 指数:32论文数:199被引数:3,616
M
Martin Reichel
H 指数:44论文数:136被引数:6,328