未登录 Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes Higdon, Lauren E.; Cooney, Laura A.; Serti, Elisavet; Suwannasaen, Duangchan; Muir, Virginia S.; Wiedeman, Alice E.; Harris, Kristina M.; Pardo, Jorge; Anderson, Mark S.; Speake, Cate; Nepom, Gerald T.; Linsley, Peter S.; Sanda, Srinath; Long, S. Alice 分享 收藏
Donor-specific immune senescence as a candidate biomarker of operational tolerance following liver transplantation in adults: Results of a prospective, multicenter cohort study 供者特异性免疫衰老作为成人肝移植后操作耐受的候选生物标志物：一项前瞻性、多中心队列研究的结果 Tanimine, Naoki; Markmann, James F.; Wood-Trageser, Michelle A.; Demetris, Anthony J.; Mason, Kristen; Silva, Juliete A. F.; Levitsky, Josh; Feng, Sandy; Humar, Abhinav; Emond, Jean C.; Shaked, Abraham; Klintmalm, Goran; Sanchez-Fueyo, Alberto; Lesniak, Drew; Breeden, Cynthia P.; Nepom, Gerald T.; Bridges, Nancy D.; Goldstein, Julia; Larsen, Christian P.; DesMarais, Michele; Gaile, Geo; Chandran, Sindhu 分享 收藏
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Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue 调节性T细胞使用乙酰肝素酶获取与发炎组织中细胞外基质结合的IL-2 Martinez, Hunter A.; Koliesnik, Ievgen; Kaber, Gernot; Reid, Jacqueline K.; Nagy, Nadine; Barlow, Graham; Falk, Ben A.; Medina, Carlos O.; Hargil, Aviv; Zihsler, Svenja; Vlodavsky, Israel; Li, Jin-Ping; Perez-Cruz, Magdiel; Tang, Sai-Wen; Meyer, Everett H.; Wrenshall, Lucile E.; Lord, James D.; Garcia, K. Christopher; Palmer, Theo D.; Steinman, Lawrence; Nepom, Gerald T.; Wight, Thomas N.; Bollyky, Paul L.; Kuipers, Hedwich F. 分享 收藏
Islet-autoreactive CD4+T cells are linked with response to alefacept in type 1 diabetes Balmas, Elisa; Chen, Janice; Hu, Alex K.; DeBerg, Hannah A.; Rosasco, Mario G.; Gersuk, Vivian H.; Serti, Elisavet; Speake, Cate; Greenbaum, Carla J.; Nepom, Gerald T.; Linsley, Peter S.; Cerosaletti, Karen 分享 收藏
A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab Mathieu, Chantal; Wiedeman, Alice; Cerosaletti, Karen; Long, S. Alice; Serti, Elisavet; Cooney, Laura; Vermeiren, Joan; Caluwaerts, Silvia; Van Huynegem, Karolien; Steidler, Lothar; Blomme, Sven; Rottiers, Pieter; Nepom, Gerald T.; Herold, Kevan C. 分享 收藏
Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy Calise, Justine; DeBerg, Hannah; Garabatos, Nahir; Khosa, Sugandhika; Bajzik, Veronique; Calderon, Lorena Botero; Aldridge, Kelly; Rosasco, Mario; Ferslew, Brian C.; Zhu, Tong; Smulders, Ronald; Wheatley, Lisa M.; Laidlaw, Tanya M.; Qin, Tielin; Chichili, Gurunadh R.; Adelman, Daniel C.; Farrington, Mary; Robinson, David; Jeong, David; Jones, Stacie M.; Sanda, Srinath; Larson, David; Kwok, William W.; Baloh, Carolyn; Nepom, Gerald T.; Wambre, Erik 分享 收藏
Epidermal differentiation complex genetic variation in atopic dermatitis and peanut allergy 特应性皮炎和花生过敏的表皮分化复合体遗传变异 Huffaker, Michelle F.; Kanchan, Kanika; Bahnson, Henry T.; Ruczinski, Ingo; Shankar, Gautam; Leung, Donald Y. M.; Baloh, Carolyn; Du Toit, George; Lack, Gideon; Nepom, Gerald T.; Mathias, Rasika A. 分享 收藏
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Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: A randomized controlled trial 特泽帕鲁单抗联合过敏原免疫疗法对鼻腔过敏原反应的影响：一项随机对照试验 Corren, Jonathan; Larson, David; Altman, Matthew C.; Segnitz, R. Max; Avila, Pedro C.; Greenberger, Paul A.; Baroody, Fuad; Moss, Mark H.; Nelson, Harold; Burbank, Allison J.; Hernandez, Michelle L.; Peden, David; Saini, Sarbjit; Tilles, Stephen; Hussain, Iftikhar; Whitehouse, Don; Qin, Tielin; Villarreal, Miguel; Sever, Michelle; Wheatley, Lisa M.; Nepom, Gerald T.; Sanda, Srinath 分享 收藏
IL-6-targeted therapies to block the cytokine or its receptor drive distinct alterations in T cell function Speake, Cate; Habib, Tania; Lambert, Katharina; Hundhausen, Christian; Lord, Sandra; Dufort, Matthew J.; Skinner, Samuel O.; Hu, Alex; Kinsman, MacKenzie; Jones, Britta E.; Maerz, Megan D.; Tatum, Megan; Hocking, Anne M.; Nepom, Gerald T.; Greenbaum, Carla J.; Buckner, Jane H. 分享 收藏
HLA-associated outcomes in peanut oral immunotherapy trials identify mechanistic and clinical determinants of therapeutic success Kanchan, Kanika; Shankar, Gautam; Huffaker, Michelle F. F.; Bahnson, Henry T. T.; Chinthrajah, R. Sharon; Sanda, Srinath; Manohar, Monali; Ling, Hua; Paschall, Justin E. E.; Toit, George Du; Ruczinski, Ingo; Togias, Alkis; Lack, Gideon; Nadeau, Kari C. C.; Jones, Stacie M. M.; Nepom, Gerald T. T.; Mathias, Rasika A. A. 分享 收藏
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HLA alleles and sustained peanut consumption promote IgG4 responses in subjects protected from peanut allergy Kanchan, Kanika; Grinek, Stepan; Bahnson, Henry T.; Ruczinski, Ingo; Shankar, Gautam; Larson, David; Du Toit, George; Barnes, Kathleen C.; Sampson, Hugh A.; Suarez-Farinas, Mayte; Lack, Gideon; Nepom, Gerald T.; Cerosaletti, Karen; Mathias, Rasika A. 分享 收藏
Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes Linsley, Peter S.; Barahmand-Pour-Whitman, Fariba; Balmas, Elisa; DeBerg, Hannah A.; Flynn, Kaitlin J.; Hu, Alex K.; Rosasco, Mario G.; Chen, Janice; O'Rourke, Colin; Serti, Elisavet; Gersuk, Vivian H.; Motwani, Keshav; Seay, Howard R.; Brusko, Todd M.; Kwok, William W.; Speake, Cate; Greenbaum, Carla J.; Nepom, Gerald T.; Cerosaletti, Karen 分享 收藏
Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy Shamji, Mohamed H.; Larson, David; Eifan, Aarif; Scadding, Guy W.; Qin, Tielin; Lawson, Kaitie; Sever, Michelle L.; Macfarlane, Ellen; Layhadi, Janice A.; Wurtzen, Peter A.; Parkin, Rebecca, V; Sanda, Srinath; Harris, Kristina M.; Nepom, Gerald T.; Togias, Alkis; Durham, Stephen R. 分享 收藏
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