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收藏Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial diseaseCaspase-11 在 Polg 相关线粒体疾病模型中驱动巨噬细胞过度炎症反应
Vanportfliet, Jordyn J.; Lei, Yuanjiu; Ramanathan, Muthumeena; Martinez, Camila Guerra; Wong, Jessica; Stodola, Tim J.; Hoffmann, Brian R.; Pflug, Kathryn; Sitcheran, Raquel; Kneeland, Stephen C.; Murray, Stephen A.; McGuire, Peter. J.; Cannon, Carolyn L.; West, A. Phillip
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收藏Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP exportATP结合盒转运蛋白ABCC1的结构揭示了环二核苷酸cGAMP外排的分子基础
Shinde, Omkar; Boyer, Joshua A.; Cambier, Stephanie; Vanportfliet, Jordyn J.; Sui, Xuewu; Yadav, Gaya P.; Viverette, Elizabeth G.; Borgnia, Mario J.; West, A. Phillip; Zhang, Qi; Stetson, Daniel B.; Li, Pingwei
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收藏Inflammatory and interferon gene expression signatures in patients with mitochondrial disease
Warren, Emily B.; Gordon-Lipkin, Eliza M.; Cheung, Foo; Chen, Jinguo; Mukherjee, Amrita; Apps, Richard; Tsang, John S.; Jetmore, Jillian; Schlein, Melissa L.; Kruk, Shannon; Lei, Yuanjiu; West, A. Phillip; McGuire, Peter J.
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收藏Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT
Al Khatib, Iman; Deng, Jingti; Lei, Yuanjiu; Torres-Odio, Sylvia; Rojas, Gladys R.; Newman, Laura E.; Chung, Brian K.; Symes, Andrew; Zhang, Hongliang; Huang, Shar-yin N.; Pommier, Yves; Khan, Aneal; Shadel, Gerald S.; West, Andrew Phillip; Gibson, William T.; Shutt, Timothy E.
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收藏CLPP Depletion Causes Diplotene Arrest; Underlying Testis Mitochondrial Dysfunction Occurs with Accumulation of Perrault Proteins ERAL1, PEO1, and HARS2
Key, Jana; Gispert, Suzana; Koornneef, Lieke; Sleddens-Linkels, Esther; Kohli, Aneesha; Torres-Odio, Sylvia; Koepf, Gabriele; Amr, Shady; Reichlmeir, Marina; Harter, Patrick N.; West, Andrew Phillip; Muench, Christian; Baarends, Willy M.; Auburger, Georg
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收藏Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA肽酶ClpP的失活导致线粒体解聚酶ClpX及其相互作用的类核蛋白和mtDNA的主要积累
Key, Jana; Torres-Odio, Sylvia; Bach, Nina C.; Gispert, Suzana; Koepf, Gabriele; Reichlmeir, Marina; West, A. Phillip; Prokisch, Holger; Freisinger, Peter; Newman, William G.; Shalev, Stavit; Sieber, Stephan A.; Wittig, Ilka; Auburger, Georg
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