Sabine Ehrt - Publications, H-index & Citations

Sabine Ehrt

Weill Cornell Medical College

65H指数

169论文数

1.6W被引数

收录论文 74

发表时间

Bacille Calmette–Guérin Vaccination With Adjunctive A Proliferation–Inducing Ligand Immunotherapy Reduces Tuberculosis Relapse in Mice 卡介苗接种联合A增殖诱导配体免疫疗法可降低小鼠结核病复发

The Journal of Infectious Diseases

IF0

2026-08-12

OAAI

Chen-Yu Tsai; Min Xie; Melissa Cristaldo; Gabriella R Peluso; Joshua Woo; Frank Nuritdinov; Narineh M Odjourian; Maureen Dougher; Rosleine Antilus-Sainte; Kaj M Kreutzfeldt; Sabine Ehrt; Martin Gengenbacher; null

Mycobacterium tuberculosis long-chain fatty acid resistome reveals universal stress protein TB15.3 as essential for infection 结核分枝杆菌长链脂肪酸抗性组揭示普遍应激蛋白TB15.3对感染至关重要

Communications Biology

IF5.1

2026-04-19

OAAI

Alexandre J. Pinto; Marco Silva; Joana A. Santos; Brian C. VanderVen; Rodrigo Monteiro; Dirk Schnappinger; Sabine Ehrt; Tiago Beites

A periplasmic protein complex mediates arabinofuranosyltransferase activity and intrinsic drug resistance in Mycobacterium tuberculosis 一个周质蛋白复合物介导分枝杆菌中阿拉伯呋喃糖基转移酶活性和固有药物抗性

Science Advances

IF12.5

2026-04-01

OAAI

Thaís Klevorn; Christopher Brown; Christine D. Hardy; Bonnie J. Cuthbert; Amanda Spencer; Adrián Jinich; Luming Chan; Shiva K. Angala; Jordan Manzer; Jessica Mendoza; Rodger de Miranda; Heather Kim; Dirk Schnappinger; Mary Jackson; Kyu Rhee; Celia W. Goulding; Sabine Ehrt

Activation of l-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis 激活l-组氨酸生物合成作为对抗结核分枝杆菌的新抗生素策略

Nature Communications

IF15.7

2026-03-21

OAAI

Debbie M. Hunt; João Pedro Pisco; Angela Rodgers; Cesira de Chiara; Anisha Zaveri; Kamila L. Pacholarz; Dimitrios Evangelopoulos; Acely Garza-Garcia; Sabine Ehrt; Dirk Schnappinger; Perdita E. Barran; Maximiliano G. Gutierrez; Luiz Pedro S. de Carvalho

Reference-based chemical-genetic interaction profiling to elucidate small molecule mechanism of action in Mycobacterium tuberculosis 基于参照的化学遗传相互作用谱分析，以阐明小分子在分枝杆菌中的作用机制

Nature Communications

IF15.7

2025-11-03

OAAI

Austin N. Bond; Marek Orzechowski; Shuting Zhang; Ishay Ben-Zion; Allison Lemmer; Nathaniel Garry; Katie Lee; Michael Chen; Kayla Delano; Emily Gath; A. Lorelei Golas; Raymond Nietupski; Michael Fitzgerald; Sabine Ehrt; Eric J. Rubin; Christopher M. Sassetti; Dirk Schnappinger; Noam Shoresh; Diana K. Hunt; James E. Gomez; Deborah T. Hung

An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH

MBIO

IF4.7

2025-01-08

PREAI

Healy, Claire; Ehrt, Sabine; Gouzy, Alexandre

Interruption of mycothiol synthesis and intracellular redox status impact iron-regulated reporter activation in Mycobacterium smegmatis

MICROBIOLOGY SPECTRUM

IF3.8

2024-07-02

OAAI

Miller, Alexandra H.; Marks, Frances; Chan, Luming; Botella, Helene; Schnappinger, Dirk; Ehrt, Sabine

Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin

NATURE COMMUNICATIONS

IF15.7

2024-05-16

OAAI

Qu, Di; Ge, Peng; Botella, Laure; Park, Sae Woong; Lee, Ha-Na; Thornton, Natalie; Bean, James M.; Krieger, Inna V.; Sacchettini, James C.; Ehrt, Sabine; Aldrich, Courtney C.; Schnappinger, Dirk

Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation

MBIO

IF4.7

2023-12-19

OAAI

Xu, Yuanyuan; Ehrt, Sabine; Schnappinger, Dirk; Beites, Tiago

Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake

PLOS PATHOGENS

IF4.9

2023-09-25

OAAI

de Miranda, Rodger; Cuthbert, Bonnie J.; Klevorn, Thais; Chao, Alex; Mendoza, Jessica; Arbing, Mark; Sieminski, Paul J.; Papavinasasundaram, Kadamba; Abdul-Hafiz, Sumer; Chan, Sum; Sassetti, Christopher M.; Ehrt, Sabine; Goulding, Celia W.

Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis

MBIO

IF4.7

2023-06-23

OAAI

Sharma, Ritu; Hartman, Travis E.; Beites, Tiago; Kim, Jee-Hyun; Eoh, Hyungjin; Engelhart, Curtis A.; Zhu, Linnan; Wilson, Daniel J.; Aldrich, Courtney C.; Ehrt, Sabine; Rhee, Kyu Young; Schnappinger, Dirk

Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis

ELIFE

IF0

2023-02-22

OAAI

Wong, Andrew, I; Beites, Tiago; Planck, Kyle A.; Fieweger, Rachael A.; Eckartt, Kathryn A.; Li, Shuqi; Poulton, Nicholas C.; VanderVen, Brian C.; Rhee, Kyu Y.; Schnappinger, Dirk; Ehrt, Sabine; Rock, Jeremy

Elucidating Iron Transport in the Periplasm of Mycobacterium tuberculosis

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-01

OAAI

de Miranda, Rodger; Chao, Alex; Klevorn, Thais; Sieminski, Paul; Abdul-Hafiz, Sumer; Ehrt, Sabine; Goulding, Celia

A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis

NATURE COMMUNICATIONS

IF15.7

2022-04-26

OAAI

Zhang, Lei; Kent, James E.; Whitaker, Meredith; Young, David C.; Herrmann, Dominik; Aleshin, Alexander E.; Ko, Ying-Hui; Cingolani, Gino; Saad, Jamil S.; Moody, D. Branch; Marassi, Francesca M.; Ehrt, Sabine; Niederweis, Michael

CinA mediates multidrug tolerance in Mycobacterium tuberculosis

NATURE COMMUNICATIONS

IF15.7

2022-04-22

OAAI

Kreutzfeldt, Kaj M.; Jansen, Robert S.; Hartman, Travis E.; Gouzy, Alexandre; Wang, Ruojun; Krieger, Inna, V; Zimmerman, Matthew D.; Gengenbacher, Martin; Sarathy, Jansy P.; Xie, Min; Dartois, Veronique; Sacchettini, James C.; Rhee, Kyu Y.; Schnappinger, Dirk; Ehrt, Sabine

Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-04-05

OAAI

Koh, Eun-Ik; Oluoch, Peter O.; Ruecker, Nadine; Proulx, Megan K.; Soni, Vijay; Murphy, Kenan C.; Papavinasasundaram, Kadamba; Reames, Charlotte J.; Trujillo, Carolina; Zaveri, Anisha; Zimmerman, Matthew D.; Aslebagh, Roshanak; Baker, Richard E.; Shaffer, Scott A.; Guinn, Kristine M.; Fitzgerald, Michael; Dartois, Veronique; Ehrt, Sabine; Hung, Deborah T.; Ioerger, Thomas R.; Rubin, Eric J.; Rhee, Kyu Y.; Schnappinger, Dirk; Sassetti, Christopher M.

Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection

NATURE COMMUNICATIONS

IF15.7

2021-11-15

OAAI

Beites, Tiago; Jansen, Robert S.; Wang, Ruojun; Jinich, Adrian; Rhee, Kyu Y.; Schnappinger, Dirk; Ehrt, Sabine

Multiform antimicrobial resistance from a metabolic mutation

SCIENCE ADVANCES

IF12.5

2021-08-27

OAAI

Schrader, Sarah M.; Botella, Helene; Jansen, Robert; Ehrt, Sabine; Rhee, Kyu; Nathan, Carl; Vaubourgeix, Julien

Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity 结核分枝杆菌在酸性pH下的生长取决于脂质同化，并伴有GAPDH活性降低

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-08-02

OAAI

Gouzy, Alexandre; Healy, Claire; Black, Katherine A.; Rhee, Kyu Y.; Ehrt, Sabine

Genetic models of latent tuberculosis in mice reveal differential influence of adaptive immunity

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2021-07-16

OAAI

Su, Hongwei; Lin, Kan; Tiwari, Divya; Healy, Claire; Trujillo, Carolina; Liu, Yao; Ioerger, Thomas R.; Schnappinger, Dirk; Ehrt, Sabine

研究方向