Thomas R. Ioerger - Publications, H-index & Citations

Thomas R. Ioerger

I Shou University

60H指数

325论文数

1.9W被引数

收录论文 109

发表时间

Evaluating selection at intermediate scales within genes provides robust identification of genes under positive selection in M. tuberculosis clinical isolates 评估基因内中等尺度上的选择作用，为识别在结核分枝杆菌临床分离株中受到正向选择的基因提供了稳健的方法。

Tuberculosis

IF2.9

2025-09-11

OAAI

Thomas R. Ioerger; Anthony Shatby

Genomic and Phenotypic Insights Into Antibiotic Resistance and Virulence of Klebsiella pneumoniae From the Environment in Southern Taiwan 来自中国台湾南部环境中克雷伯氏肺炎杆菌的抗生素耐药性和毒力的基因组与表型见解

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2025-08-01

OAAI

Liao, Chun-Hsing; Huang, Ya-Ling; Ioerger, Thomas; Lim, Ke San; Huang, Yu-Chieh; Huang, Chen-Hsiu; Hsu, Chun-Ru

SuFEx-based antitubercular compound irreversibly inhibits Pks13 基于SuFEx的抗结核化合物不可逆地抑制Pks13

Nature

IF48.5

2025-07-30

PREAI

Inna V. Krieger; Paridhi Sukheja; Baiyuan Yang; Su Tang; Daniel Selle; Ashley Woods; Curtis Engelhart; Pradeep Kumar; Michael B. Harbut; Dongdong Liu; Brendan Tsuda; Bo Qin; Grant A. L. Bare; Gencheng Li; Victor Chi; Julian Gambacurta; Janine Hvizdos; Matthew Reagan; Isabelle L. Jones; Lisa M. Massoudi; Lisa K. Woolhiser; Alessandro Cascioferro; Erica Kundrick; Parul Singh; William Reiley; Thomas R. Ioerger; Dilipkumar Reddy Kandula; Jacob W. McCabe; Taijie Guo; David Alland; Helena I. Boshoff; Dirk Schnappinger; Gregory T. Robertson; Khisi Mdluli; Kyoung-Jin Lee; Jiajia Dong; Shuangwei Li; Peter G. Schultz; Sean B. Joseph; Melissa S. Love; K. Barry Sharpless; H. Michael Petrassi; Arnab K. Chatterjee; James C. Sacchettini; Case W. McNamara

The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB): A Large-Scale Guide to Genetic Conditional Essentiality 结核分枝杆菌转座子测序数据库 (MtbTnDB)：遗传条件必需性的大规模指南

Molecular Microbiology

IF2.6

2025-06-17

OAAI

Adrian Jinich; Anisha Zaveri; Michael A. DeJesus; Amanda Spencer; Ricardo Almada-Monter; Emanuel Flores-Bautista; Clare M. Smith; Christopher M. Sassetti; Jeremy M. Rock; Sabine Ehrt; Dirk Schnappinger; Thomas R. Ioerger; Kyu Y. Rhee

TnSeq identifies genetic requirements of Mycobacterium tuberculosis for survival under vaccine-induced immunity TnSeq鉴定了分枝杆菌 *Mycobacterium tuberculosis* 在疫苗诱导的免疫条件下的生存遗传需求

NPJ VACCINES

IF6.5

2025-05-22

OAAI

James, Kimra S.; Jain, Neharika; Witzl, Kelly; Cicchetti, Nico; Fortune, Sarah M.; Ioerger, Thomas R.; Martinot, Amanda J.; Carey, Allison F.

Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis 鉴定一类含有五氟苯基结构单元的化合物，该化合物靶向Pks13以抑制结核分枝杆菌的生长。

ACS INFECTIOUS DISEASES

IF3.8

2025-02-27

OAAI

Green, SR; Harrison, JR; Thompson, S; Murugesan, D; Libardo, MDJ; Engelhart, CA; Meshanni, J; Fletcher, D; Scullion, P; Edwards, D; Epemolu, O; Mutter, N; Shishikura, Y; Riley, J; Ioerger, TR; Guillén, JJR; López, LG; Read, KD; Barry, CE III; Schnappinger, D; Wyatt, PG; Boshoff, HIM; Cleghorn, LAT

Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains

MBIO

IF4.7

2025-02-05

PREAI

Akusobi, Chidiebere; Choudhery, Sanjeevani; Benghomari, Bouchra S.; Wolf, Ian D.; Singhvi, Shreya; Ioerger, Thomas R.; Rubin, Eric J.

Frequently arising ESX-1-associated phase variants influence Mycobacterium tuberculosis fitness in the presence of host and antibiotic pressures

MBIO

IF4.7

2025-01-28

OAAI

Luna, Michael J.; Oluoch, Peter O.; Miao, Jiazheng; Culviner, Peter; Papavinasasundaram, Kadamba; Jaecklein, Eleni; Shell, Scarlet S.; Ioerger, Thomas R.; Fortune, Sarah M.; Farhat, Maha R.; Sassetti, Christopher M.

The anti-tubercular callyaerins target the Mycobacterium tuberculosis-specific non-essential membrane protein Rv2113

CELL CHEMICAL BIOLOGY

IF7.2

2024-10-01

OAAI

Podlesainski, David; Adeniyi, Emmanuel T.; Groener, Yvonne; Schulz, Florian; Krisilia, Violetta; Rehberg, Nidja; Richter, Tim; Sehr, Daria; Xie, Huzhuyue; Simons, Viktor E.; Kiffe-Delf, Anna-Lene; Kaschani, Farnusch; Ioerger, Thomas R.; Kaiser, Markus; Kalscheuer, Rainer

Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most Mycolicibacterium smegmatis mRNAs

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-11-01

OAAI

Zhou, Ying; Sun, Huaming; Rapiejko, Abigail R.; Vargas-Blanco, Diego A.; Martini, Maria Carla; Chase, Michael R.; Joubran, Samantha R.; Davis, Alexa B.; Dainis, Joseph P.; Kelly, Jessica M.; Ioerger, Thomas R.; Roberts, Louis A.; Fortune, Sarah M.; Shell, Scarlet S.

Functional Whole Genome Screen of Nutrient-Starved Mycobacterium tuberculosis Identifies Genes Involved in Rifampin Tolerance

MICROORGANISMS

IF4.2

2023-09-09

OAAI

Matern, William M.; Harris, Harley T.; Danchik, Carina; McDonald, Marissa; Patel, Gopi; Srivastava, Aashish; Ioerger, Thomas R.; Bader, Joel S.; Karakousis, Petros C.

The Rip1 intramembrane protease contributes to iron and zinc homeostasis in Mycobacterium tuberculosis

MSPHERE

IF3.1

2023-08-24

OAAI

Nelson, Samantha J. J.; Williams, John T. T.; Buglino, John A. A.; Nambi, Subhalaxmi; Lojek, Lisa J. J.; Glickman, Michael S. S.; Ioerger, Thomas R. R.; Sassetti, Christopher M. M.

Synthesis and Structure-Activity Relationships of a New Class of Oxadiazoles Targeting DprE1 as Antitubercular Agents 靶向DprE1的新型恶二唑类抗结核药的合成和构效关系

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2023-08-15

OAAI

Yadav, Veena D. D.; Boshoff, Helena I. I.; Trifonov, Lena; Roma, Jose Santinni O.; Ioerger, Thomas R. R.; Barry, Clifton E. E.; Oh, Sangmi

Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-07-03

OAAI

Vargas Jr, Roger; Luna, Michael J.; Freschi, Luca; Marin, Maximillian; Froom, Ruby; Murphy, Kenan C.; Campbell, Elizabeth A.; Ioerger, Thomas R.; Sassetti, Christopher M.; Farhat, Maha Reda

A mutant fitness assay identifies bacterial interactions in a model ocean hot spot 突变体适应性测定可识别模型海洋热点中的细菌相互作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-03-15

OAAI

Schreier, Jeremy E.; Smith, Christa B.; Ioerger, Thomas R.; Moran, Mary Ann

The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-01-05

OAAI

Koller, Timm O.; Scheid, Ullrich; Koesel, Teresa; Herrmann, Jennifer; Krug, Daniel; Boshoff, Helena I. M.; Beckert, Bertrand; Evans, Joanna C.; Schlemmer, Jan; Sloan, Becky; Weiner, Danielle M.; Via, Laura E.; Moosa, Atica; Ioerger, Thomas R.; Graf, Michael; Zinshteyn, Boris; Abdelshahid, Maha; Nguyen, Fabian; Arenz, Stefan; Gille, Franziska; Siebke, Maik; Seedorf, Tim; Plettenburg, Oliver; Green, Rachel; Warnke, Anna-Luisa; Ullrich, Joachim; Warrass, Ralf; Barry, Clifton E., III; Warner, Digby F.; Mizrahi, Valerie; Kirschning, Andreas; Wilson, Daniel N.; Mueller, Rolf

1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis 1，3-二芳基吡唑基酰基磺酰胺靶向结核分枝杆菌中的HadAB/BC复合物

ACS INFECTIOUS DISEASES

IF3.8

2022-11-03

OAAI

Singh, Vinayak; Grzegorzewicz, Anna E.; Fienberg, Stephen; Muller, Rudolf; Khonde, Lutete Peguy; Sanz, Olalla; Alfonso, Salvatore; Urones, Beatriz; Drewes, Gerard; Bantscheff, Marcus; Ghidelli-Disse, Sonja; Ioerger, Thomas R.; Angala, Bhanupriya; Liu, Jiuyu; Lee, Richard E.; Sacchettini, James C.; Krieger, Inna, V; Jackson, Mary; Chibale, Kelly; Ghorpade, Sandeep R.

Deletion of Rv2571c Confers Resistance to Arylamide Compounds in Mycobacterium tuberculosis (65, e02334, 2021)

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2022-08-16

OAAI

Shelton, Catherine D.; McNeil, Matthew B.; Early, Julie V.; Ioerger, Thomas R.; Parish, Tanya

Transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding protein involved in septal peptidoglycan synthesis and antibiotic sensitivity

ELIFE

IF0

2022-06-06

OAAI

Akusobi, Chidiebere; Benghomari, Bouchra S.; Zhu, Junhao; Wolf, Ian D.; Singhvi, Shreya; Dulberger, Charles L.; Ioerger, Thomas R.; Rubin, Eric J.; Kana, Bavesh D.

Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-04-05

OAAI

Koh, Eun-Ik; Oluoch, Peter O.; Ruecker, Nadine; Proulx, Megan K.; Soni, Vijay; Murphy, Kenan C.; Papavinasasundaram, Kadamba; Reames, Charlotte J.; Trujillo, Carolina; Zaveri, Anisha; Zimmerman, Matthew D.; Aslebagh, Roshanak; Baker, Richard E.; Shaffer, Scott A.; Guinn, Kristine M.; Fitzgerald, Michael; Dartois, Veronique; Ehrt, Sabine; Hung, Deborah T.; Ioerger, Thomas R.; Rubin, Eric J.; Rhee, Kyu Y.; Schnappinger, Dirk; Sassetti, Christopher M.

研究方向