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C

Colby R. Maldini

beam therapeutics
H指数:13
被引数:1,026

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Clinical Trial Results Provide the Rationale to Protect Dual HIV-specific T Cells with a Signaling-Defective HIV Fusion Inhibitor

临床 trial 结果提供了保护 dual HIV-specific T cells 的 rationale，其方法是使用一种 signaling-defective HIV fusion inhibitor。

Molecular Therapy
IF12
2026-01-100
PRE
Pablo Tebas; Julie K. Jadlowsky; Yuqi Zhou; M.Betina Pampena; George J. Leslie; Nan Liu; Sriram Srivatsa; Colby R. Maldini; Jingxin Wang; Chungdhak Jaming Tsang; Ola Mohamed; Josephine Romano; Beth Haggarty; Gabriela Plesa; Avery L. Gaymon; Andrea L. Brennan; Elizabeth Veloso; Bruce L. Levine; Mary E. Putt; Irina Kulikovskaya
Multiplex gene-editing strategy to engineer allogeneic EGFR-targeting CAR T-cells with improved efficacy against solid tumors

一种多基因编辑策略，用于构建具有增强实体瘤抗性的同种异基因EGFR靶向CAR T细胞

Nature Communications
IF15.7
2025-11-230
OAAI
Ryan Murray; Md Raihan Chowdhury; Nuria Roxana Botticello-Romero; Kashvi Desai; Shanmuga Reddy Chilakapati; Brian Chong; Yixue Xia; Angelica Messana; Hanna Sobon; Joe Rocha; Faith Musenge; Adam Camblin; Giuseppe Ciaramella; Michail V. Sitkovsky; Colby R. Maldini; Stephen M. Hatfield
CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication (vol 131, e144486, 2021)
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-05-011
OAAI
Tebas, Pablo; Jadlowsky, Julie K.; Shaw, Pamela A.; Tian, Lifeng; Esparza, Erin; Brennan, Andrea L.; Kim, Sukyung; Naing, Soe Yu; Richardson, Max W.; Vogel, Ashley N.; Maldini, Colby R.; Kong, Hong; Liu, Xiaojun; Lacey, Simon F.; Bauer, Anya M.; Mampe, Felicity; Richman, Lee P.; Lee, Gary; Ando, Dale; Levine, Bruce L.; Porter, David L.; Zhao, Yangbing; Siegel, Don L.; Bar, Katharine J.; June, Carl H.; Riley, James L.
Quantitative immunopeptidomics reveals a tumor stroma-specific target for T cell therapy

定量免疫流行病学揭示了T细胞治疗的肿瘤基质特异性靶标

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-08-3121
OA
Kim, Gloria B.; Fritsche, Jens; Bunk, Sebastian; Mahr, Andrea; Unverdorben, Felix; Tosh, Kevin; Kong, Hong; Maldini, Colby R.; Lau, Chui; Srivatsa, Sriram; Jiang, Shuguang; Glover, Joshua; Dopkin, Derek; Zhang, Carolyn X.; Schuster, Heiko; Kowalewski, Daniel J.; Goldfinger, Valentina; Ott, Martina; Fuhrmann, David; Baues, Maike; Boesmueller, Hans; Schraeder, Christoph; Schimmack, Gisela; Song, Colette; Hoffgaard, Franziska; Roemer, Michael; Tsou, Chih-Chiang; Hofmann, Martin; Treiber, Thomas; Hutt, Meike; Alten, Leonie; Jaworski, Maike; Alpert, Amir; Missel, Sarah; Reinhardt, Carsten; Singh, Harpreet; Schoor, Oliver; Walter, Steffen; Wagner, Claudia; Maurer, Dominik; Weinschenk, Toni; Riley, James L.
CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-04-0160
OA
Tebas, Pablo; Jadlowsky, Julie K.; Shaw, Pamela A.; Tian, Lifeng; Esparza, Erin; Brennan, Andrea L.; Kim, Sukyung; Naing, Soe Yu; Richardson, Max W.; Vogel, Ashley N.; Maldini, Colby R.; Kong, Hong; Liu, Xiaojun; Lacey, Simon F.; Bauer, Anya M.; Mampe, Felicity; Richman, Lee P.; Lee, Gary; Ando, Dale; Levine, Bruce L.; Porter, David L.; Zhao, Yangbing; Siegel, Don L.; Bar, Katharine J.; June, Carl H.; Riley, James L.
Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo

具有不同共刺激结构域的双CD4-based CAR T细胞在体内减轻HIV发病机制

NATURE MEDICINE
IF50
2020-08-3173
OAAI
Maldini, Colby R.; Claiborne, Daniel T.; Okawa, Ken; Chen, Tao; Dopkin, Derrick L.; Shan, Xiaochuan; Power, Karen A.; Trifonova, Radiana T.; Krupp, Katharine; Phelps, Meredith; Vrbanac, Vladimir D.; Tanno, Serah; Bateson, Timothy; Leslie, George J.; Hoxie, James A.; Boutwell, Christian L.; Riley, James L.; Allen, Todd M.
Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia

BLT人源化小鼠的预防接种可重定向T细胞对Gag的反应并减少急性HIV-1病毒血症

JOURNAL OF VIROLOGY
IF3.8
2019-10-1524
OAAI
Claiborne, Daniel T.; Dudek, Timothy E.; Maldini, Colby R.; Power, Karen A.; Ghebremichael, Musie; Seung, Edward; Mellors, Elizabeth F.; Vrbanac, Vladimir D.; Krupp, Katharine; Bisesi, Abigail; Tager, Andrew M.; Knipe, David M.; Boutwell, Christian L.; Allen, Todd M.

研究方向

暂未获取到该数据
J
James L. Riley
H 指数:76论文数:278被引数:2.6万
J
Julie K. Jadlowsky
H 指数:19论文数:68被引数:3,764
T
Todd M. Allen
H 指数:92论文数:393被引数:2.6万
D
Daniel T. Claiborne
H 指数:17论文数:147被引数:1,302
V
Vladimir Vrbanac
H 指数:25论文数:61被引数:3,799
C
Christian L. Boutwell
H 指数:14论文数:35被引数:1,750
S
Simon F. Lacey
H 指数:75论文数:382被引数:3.8万
K
Karen A. Power
H 指数:35论文数:130被引数:4,177
H
Hong Kong
H 指数:12论文数:53被引数:930
A
Andrea Brennan
H 指数:15论文数:93被引数:2,019