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J

Jayakrishna Ambati

University of Virginia School of Medicine
H指数:49
被引数:1.5万

个人简介

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教育背景

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荣誉奖项

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The nucleoside analog kamuvudine-9 shows protective and therapeutic efficacy in a mouse model of multiple sclerosis

核苷类似物卡慕夫定-9在多发性硬化症小鼠模型中显示出保护和治疗功效

Science Translational Medicine
IF14.6
2026-09-230
PRE
Praveen Yerramothu; Kameshwari Ambati; Joseph Magagnoli; Meenakshi Ambati; Thendral Velmurugan; Dijing Yu; Jing Zhang; Jingjing Zhang; Tammy Cummings; Joseph Nguyen; Claire C. Thomas; Vidya L. Ambati; Kaitlyn Cheng; Maksud Juraev; Roshni Dholkawala; Felipe Pereira; Peirong Huang; Ayami Nagasaka; Yosuke Nagasaka; Madhuri Rudraraju; Ashley Ban; Ivana Apicella; Xiaoyu Cai; Ranjith Konduri; Rhea Zahir; Elizabeth Frost; John Lukens; Ruwen Yin; Frederick Brøndsted; Cliff I. Stains; Makoto Ono; Brian P. Delisle; Jamie Horn; Markos Leggas; Jeffrey L. Dupree; S. Scott Sutton; Bradley D. Gelfand; Shao-bin Wang; Jayakrishna Ambati
Oral lamivudine in diabetic macular edema: A randomized, double-blind, placebo-controlled clinical trial

口服拉米夫定治疗糖尿病黄斑水肿：一项随机、双盲、安慰剂对照临床试验

Med
IF11.8
2025-05-270
PRE
Felipe Pereira; Joseph Magagnoli; Meenakshi Ambati; Talita Fernandes de Oliveira; Juliana Angélica Estevão de Oliveira; Vinicius Oliveira Pesquero; Lucas Zago Ribeiro; Dante Akira Kondo Kuroiwa; Fernando Korn Malerbi; Sergio Atala Dib; Nilva Bueno Moraes; Michel Eid Farah; Eduardo Buchele Rodrigues; Jayakrishna Ambati
Inflammasome activation aggravates choroidal neovascularization
ANGIOGENESIS
IF9.2
2024-09-240
OAAI
Makin, Ryan D.; Apicella, Ivana; Dholkawala, Roshni; Fukuda, Shinichi; Hirahara, Shuichiro; Hirano, Yoshio; Kim, Younghee; Nagasaka, Ayami; Nagasaka, Yosuke; Narendran, Siddharth; Pereira, Felipe; Varshney, Akhil; Wang, Shao-bin; Ambati, Jayakrishna; Gelfand, Bradley D.
Kamuvudine-9 Protects Retinal Structure and Function in a Novel Model of Experimental Rhegmatogenous Retinal Detachment
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
IF4.7
2023-05-023
OAAI
Huang, Peirong; Thomas, Claire C.; Ambati, Kameshwari; Dholkawala, Roshni; Nagasaka, Ayami; Yerramothu, Praveen; Narendran, Siddharth; Pereira, Felipe; Nagasaka, Yosuke; Apicella, Ivana; Cai, Xiaoyu; Makin, Ryan D.; Magagnoli, Joseph; Stains, Cliff I.; Yin, Ruwen; Wang, Shao-bin; Gelfand, Bradley D.; Ambati, Jayakrishna
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs
SCIENCE IMMUNOLOGY
IF16.3
2021-12-2424
OA
Wang, Shao-bin; Narendran, Siddharth; Hirahara, Shuichiro; Varshney, Akhil; Pereira, Felipe; Apicella, Ivana; Ambati, Meenakshi; Ambati, Vidya L.; Yerramothu, Praveen; Ambati, Kameshwari; Nagasaka, Yosuke; Argyle, Dionne; Huang, Peirong; Baker, Kirstie L.; Marion, Kenneth M.; Gupta, Kartik; Liu, Bo; Hinton, David R.; Canna, Scott W.; Sallam, Tamer; Sada, Srinivas R.; Kerur, Nagaraj; Gelgfand, Bradley D.; Ambati, Jayakrishna
A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling

cGAMP的非规范，不依赖干扰素的信号传导活性触发DNA损伤反应信号传导

NATURE COMMUNICATIONS
IF15.7
2021-10-2742
OAAI
Banerjee, Daipayan; Langberg, Kurt; Abbas, Salar; Odermatt, Eric; Yerramothu, Praveen; Volaric, Martin; Reidenbach, Matthew A.; Krentz, Kathy J.; Rubinstein, C. Dustin; Brautigan, David L.; Abbas, Tarek; Gelfand, Bradley D.; Ambati, Jayakrishna; Kerur, Nagaraj
Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity

Alu互补DNA在萎缩性黄斑变性中富集，并通过胞质先天免疫触发视网膜色素上皮毒性

SCIENCE ADVANCES
IF12.5
2021-10-0123
OAAI
Fukuda, Shinichi; Narendran, Siddharth; Varshney, Akhil; Nagasaka, Yosuke; Wang, Shao-Bin; Ambati, Kameshwari; Apicella, Ivana; Pereira, Felipe; Fowler, Benjamin J.; Yasuma, Tetsuhiro; Hirahara, Shuichiro; Yasuma, Reo; Huang, Peirong; Yerramothu, Praveen; Makin, Ryan D.; Wang, Mo; Baker, Kirstie L.; Marion, Kenneth M.; Huang, Xiwen; Baghdasaryan, Elmira; Ambati, Meenakshi; Ambati, Vidya L.; Banerjee, Daipayan; Bonilha, Vera L.; Tolstonog, Genrich, V; Held, Ulrike; Ogura, Yuichiro; Terasaki, Hiroko; Oshika, Tetsuro; Bhattarai, Deepak; Kim, Kyung Bo; Feldman, Sanford H.; Aguirre, J. Ignacio; Hinton, David R.; Kerur, Nagaraj; Sadda, Srinivas R.; Schumann, Gerald G.; Gelfand, Bradley D.; Ambati, Jayakrishna
Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-02-0140
OA
Fukuda, Shinichi; Varshney, Akhil; Fowler, Benjamin J.; Wang, Shao-bin; Narendran, Siddharth; Ambati, Kameshwari; Yasuma, Tetsuhiro; Magagnoli, Joseph; Leung, Hannah; Hirahara, Shuichiro; Nagasaka, Yosuke; Yasuma, Reo; Apicella, Ivana; Pereira, Felipe; Makin, Ryan D.; Magner, Eamonn; Liu, Xinan; Sun, Jian; Wang, Mo; Baker, Kirstie; Marion, Kenneth M.; Huang, Xiwen; Baghdasaryan, Elmira; Ambati, Meenakshi; Ambati, Vidya L.; Pandey, Akshat; Pandya, Lekha; Cummings, Tammy; Banerjee, Daipayan; Huang, Peirong; Yerramothu, Praveen; Tolstonog, Genrich, V; Held, Ulrike; Erwin, Jennifer A.; Paquola, Apua C. M.; Herdy, Joseph R.; Ogura, Yuichiro; Terasaki, Hiroko; Oshika, Tetsuro; Darwish, Shaban; Singh, Ramendra K.; Mozaffari, Saghar; Bhattarai, Deepak; Kim, Kyung Bo; Hardin, James W.; Bennett, Charles L.; Hinton, David R.; Hanson, Timothy E.; Rover, Christian; Parang, Keykavous; Kerur, Nagaraj; Liu, Jinze; Werner, Brian C.; Sutton, S. Scott; Sadda, Srinivas R.; Schumann, Gerald G.; Gelfand, Bradley D.; Gage, Fred H.; Ambati, Jayakrishna

研究方向

暂未获取到该数据
B
Bradley D. Gelfand
H 指数:28论文数:110被引数:4,285
B
Balamurali K. Ambati
H 指数:50论文数:257被引数:1.2万
N
Nagaraj Kerur
H 指数:27论文数:78被引数:3,529
F
Felipe Pereira
H 指数:15论文数:48被引数:1,670
S
Siddharth Narendran
H 指数:18论文数:79被引数:2,215
I
Ivana Apicella
H 指数:15论文数:33被引数:943
B
Benjamin J. Fowler
H 指数:23论文数:73被引数:4,134
Y
Yosuke Nagasaka
H 指数:19论文数:79被引数:1,029
J
Joseph Magagnoli
H 指数:14论文数:81被引数:1,715
R
Reo Yasuma
H 指数:13论文数:33被引数:1,174