Robert J.C. Gilbert - Publications, H-index & Citations

Robert J.C. Gilbert

University of Oxford

57H指数

220论文数

1.2W被引数

收录论文 71

发表时间

Molecular mechanism of pore formation by Plasmodium Perforin-like Protein 2

Nature Communications

IF15.7

2026-07-31

OAAI

Yu Zhang; Lijie Zhong; Yun Song; Mingcheng Guo; Keli Ren; Tingting Yang; Yixin Huang; Ilia Sirotkin; Gangshun Yi; Fang Jiao; Peijun Zhang; Robert J. C. Gilbert; Tao Ni; Xiulian Yu

Glucocerebrosidase rescues alphasynuclein from amyloid formation in vitro 葡萄糖脑苷酶在体外阻止α-突触核蛋白的淀粉样纤维形成

Journal of Molecular Biology

IF4.5

2026-07-01

PREAI

Barber, Michael; Muller, Henrik; Gilbert, Robert J. C.; Baldwin, Andrew J.

Covalently constrained ‘Di-Gembodies’ enable parallel structure solutions by cryo-EM 共价约束的“Di-Gembodies”通过冷冻电镜实现平行结构解析

Nature Chemical Biology

IF13.7

2025-08-15

OAAI

Gangshun Yi; Dimitrios Mamalis; Mingda Ye; Loic Carrique; Michael Fairhead; Huanyu Li; Katharina L. Duerr; Peijun Zhang; David B. Sauer; Frank von Delft; Benjamin G. Davis; Robert J. C. Gilbert

Structure and unusual binding mechanism of the hyaluronan receptor LYVE-1 mediating leucocyte entry to lymphatics 透明质酸受体LYVE-1的结构及其介导白细胞进入淋巴管的特殊结合机制

NATURE COMMUNICATIONS

IF15.7

2025-03-20

OAAI

Bano, Fouzia; Banerji, Suneale; Ni, Tao; Green, Dixy E.; Cook, Kalila R.; Manfield, Iain W.; Deangelis, Paul L.; Paci, Emanuele; Lepsik, Martin; Gilbert, Robert J. C.

Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM

NATURE COMMUNICATIONS

IF15.7

2024-11-27

OAAI

Ma, Jianbing; Yi, Gangshun; Ye, Mingda; MacGregor-Chatwin, Craig; Sheng, Yuewen; Lu, Ying; Li, Ming; Li, Qingrong; Wang, Dong; Gilbert, Robert J. C.; Zhang, Peijun

In vitro evolution driven by epistasis reveals alternative cholesterol-specific binding motifs of perfringolysin O

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-09-01

OAAI

Sakanovic, Aleksandra; Kranjc, Nace; Omersa, Neza; Aden, Sasa; Kezar, Andreja; Kisovec, Matic; Zavec, Apolonija Bedina; Caserman, Simon; Gilbert, Robert J. C.; Podobnik, Marjetka; Crnkovic, Ana; Anderluh, Gregor

Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2024-07-25

OAAI

Yi, Gangshun; Ye, Mingda; Carrique, Loic; El-Sagheer, Afaf; Brown, Tom; Norbury, Chris J.; Zhang, Peijun; Gilbert, Robert J. C.

Surface plasmon resonance and microscale thermophoresis approaches for determining the affinity of perforin for calcium ions

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-07-19

OAAI

Naneh, Omar; Kozorog, Mirijam; Merzel, Franci; Gilbert, Robert; Anderluh, Gregor

Cryo-EM structures of perforin-2 in isolation and assembled on a membrane suggest a mechanism for pore formation

EMBO JOURNAL

IF8.3

2022-10-17

OAAI

Yu, Xiulian; Ni, Tao; Munson, George; Zhang, Peijun; Gilbert, Robert J. C.

Single-molecule tracking of perfringolysin O assembly and membrane insertion uncoupling

FEBS JOURNAL

IF4.2

2022-09-19

OAAI

Senior, Michael J. T.; Monico, Carina; Weatherill, Eve E.; Gilbert, Robert J.; Heuck, Alejandro P.; Wallace, Mark, I

Perforin-2 clockwise hand-over-hand pre-pore to pore transition mechanism

NATURE COMMUNICATIONS

IF15.7

2022-08-26

OAAI

Jiao, Fang; Dehez, Francois; Ni, Tao; Yu, Xiulian; Dittman, Jeremy S.; Gilbert, Robert; Chipot, Christophe; Scheuring, Simon

Editorial: Perforins and Cholesterol-Dependent Cytolysins in Immunity and Pathogenesis 社论: 穿孔素和胆固醇依赖性溶细胞素在免疫和发病机制中的作用

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-06-09

OAAI

Munson, George P.; Gilbert, Robert J. C.; Pradel, Gabriele

Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling

NATURE COMMUNICATIONS

IF15.7

2021-12-09

OAAI

Griffiths, Samuel C.; Schwab, Rebekka A.; El Omari, Kamel; Bishop, Benjamin; Iverson, Ellen J.; Malinauskas, Tomas; Dubey, Ramin; Qian, Mingxing; Covey, Douglas F.; Gilbert, Robert J. C.; Rohatgi, Rajat; Siebold, Christian

Theoretical and experimental comparisons of simple peptide-membrane systems; towards defining the reaction space: general discussion

FARADAY DISCUSSIONS

IF3.1

2021-01-01

PREAI

Aguilar, Marie-Isabel; Al Nahas, Kareem; Barrera, Francisco N.; Bassereau, Patricia; Bechinger, Burkhard; Brand, Izabella; Chattopadhyay, Amitabha; Clarke, Ronald J.; DeGrado, William F.; Deplazes, Evelyne; Fletcher, Marcus; Fraternali, Franca; Fuchs, Patrick; Garcia-Saez, Ana J.; Gilbert, Robert; Hoogenboom, Bart W.; Jarin, Zack; O'Shea, Paul; Pabst, Georg; Pal, Sreetama; Sanderson, John M.; Seddon, John M.; Sengupta, Durba; Siegel, David P.; Srivastava, Anand; Tieleman, D. Peter; Tripathy, Madhusmita; Utterstrom, Johanna; Vacha, Robert; Vanni, Stefano; Voth, Gregory A.

Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity

SCIENCE ADVANCES

IF12.5

2020-01-31

OAAI

Ni, Tao; Jiao, Fang; Yu, Xiulian; Aden, Sasa; Ginger, Lucy; Williams, Sophie, I; Bai, Fangfang; Prazak, Vojtech; Karia, Dimple; Stansfeld, Phillip; Zhang, Peijun; Munson, George; Anderluh, Gregor; Scheuring, Simon; Gilbert, Robert J. C.

Structures of monomeric and oligomeric forms of the Toxoplasma gondii perforin-like protein 1

SCIENCE ADVANCES

IF12.5

2018-03-02

OAAI

Ni, Tao; Williams, Sophie I.; Rezelj, Sasa; Anderluh, Gregor; Harlos, Karl; Stansfeld, Phillip J.; Gilbert, Robert J. C.

Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope

JOURNAL OF VIROLOGY

IF3.8

2017-11-01

OAAI

Rissanen, Ilona; Stass, Robert; Zeltina, Antra; Li, Sai; Hepojoki, Jussi; Harlos, Karl; Gilbert, Robert J. C.; Huiskonen, Juha T.; Bowden, Thomas A.

Membrane pores: from structure and assembly, to medicine and technology 膜孔: 从结构和组装到医学和技术

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2017-06-19

OAAI

Gilbert, Robert J. C.; Bayley, Hagan; Anderluh, Gregor

Repurposing a pore: highly conserved perforin-like proteins with alternative mechanisms

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2017-06-19

OAAI

Ni, Tao; Gilbert, Robert J. C.

Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain

BIOCHEMICAL JOURNAL

IF4.3

2017-02-03

OAAI

Ni, Tao; Kalli, Antreas C.; Naughton, Fiona B.; Yates, Luke A.; Naneh, Omar; Kozorog, Mirijam; Anderluh, Gregor; Sansom, Mark S. P.; Gilbert, Robert J. C.

研究方向