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S

Stephen B. Heitner

Department of Clinical Research

33H指数
227论文数
6.6K被引数
收录论文 68
发表时间
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A First-in-Human Study of Ulacamten, a Novel Cardiac Myosin Inhibitor for HFpEF乌拉卡姆滕作为新型心脏肌球蛋白抑制剂治疗HFpEF的首次人体研究
errClinical Pharmacokinetics
IF4
err2026-08-30
err0
errOAAI
errJustin D. Lutz; Neha Maharao; Tyrell Simkins; Kathleen Cheplo; Genzhou Liu; Camelia Dumitrescu; Adrienne Griffith; Rajaa Sukhun; Stephen B. Heitner; Stuart Kupfer; Polina German
err分享
err收藏
Towards a Quantitative Understanding of Aficamten Clinical Pharmacology: Pharmacokinetic-Cardiodynamic Modeling to Support Safety and Efficacy阿菲坎坦临床药理学定量理解：药代动力学-心脏动力学建模以支持安全性和有效性
errcpt: pharmacometrics & systems pharmacology
IF0
err2026-05-08
err0
errOAAI
errJustin D. Lutz; Russ Wada; Daniel L. Jacoby; Stephen B. Heitner; Stuart Kupfer; Polina German
err分享
err收藏
Clinical Evaluation of Drug–Drug Interactions With Aficamten阿菲坎特药物相互作用临床评估
errClinical and Translational Science
IF2.8
err2026-03-05
err0
errOAAI
errNeha Maharao; Donghong Xu; Punag Divanji; Tyrell J. Simkins; Jianlin Li; Camelia Dumitrescu; Priyanka Solanki; Adrienne Griffith; Stephen B. Heitner; Stuart Kupfer; Polina German; Justin D. Lutz
err分享
err收藏
Efficacy and Safety of Omecamtiv Mecarbil in Heart Failure With Reduced Ejection Fraction According to Age奥美卡替美卡比尔在射血分数降低的心力衰竭中的有效性与安全性（根据年龄）
errJACC: Heart Failure
IF0
err2025-10-22
err0
PREAI
errHenri Lu; Brian L. Claggett; G. Michael Felker; John J.V. McMurray; John R. Teerlink; Riccardo M. Inciardi; Marco Metra; Stephen B. Heitner; Rafael Diaz; Fady Malik; Muthiah Vaduganathan; Scott D. Solomon
err分享
err收藏
Safety and Efficacy of Aficamten in Patients With Nonobstructive Hypertrophic Cardiomyopathy: A 96-Week Analysis From FOREST-HCMAficamten在非梗阻性肥厚型心肌病患者的安全性与有效性：FOREST-HCM研究96周分析
errJournal of Cardiac Failure
IF8.2
err2025-09-28
err0
errOAAI
errAhmad Masri; Mark V. Sherrid; Lubna Choudhury; Pablo Garcia-Pavia; Christopher M. Kramer; Roberto Barriales-Villa; Robert M. Cooper; Perry M. Elliott; Sheila M. Hegde; Martin S. Maron; Michael E. Nassif; Artur Oreziak; Anjali T. Owens; Scott D. Solomon; Albree Tower-Rader; Stephen B. Heitner; Daniel L. Jacoby; Stuart Kupfer; Fady I. Malik; Chiara Melloni; Tyrell Simkins; Jenny Wai; Sara Saberi
err分享
err收藏
Low Incidence of Atrial Fibrillation in Patients with Obstructive HCM Treated with Aficamten: An Analysis from the REDWOOD-HCM, SEQUOIA-HCM and FOREST-HCM Trials梗阻性肥厚型心肌病患者使用Aficamten治疗后房颤发生率低：REDWOOD-HCM、SEQUOIA-HCM和FOREST-HCM试验的分析
errHeart Rhythm
IF5.7
err2025-08-31
err0
errOAAI
errEthan J. Rowin; Martin S. Maron; Iacopo Olivotto; Caroline J. Coats; Theodore P. Abraham; Michael E. Nassif; Roberto Barriales-Villa; Sara Saberi; Stephen B. Heitner; Daniel L. Jacoby; Stuart Kupfer; Fady I. Malik; Tyrell Simkins; Jenny Wei; Ahmad Masri
err分享
err收藏
Correction: Effect of Hepatic Impairment or Renal Impairment on the Pharmacokinetics of Aficamten更正：肝功能损害或肾功能损害对Aficamten药代动力学的影响
errClinical Pharmacokinetics
IF4
err2025-08-23
err0
errOAAI
errDonghong Xu; Justin D. Lutz; Punag Divanji; Jianlin Li; Youcef Benattia; Adrienne Griffith; Stephen B. Heitner; Stuart Kupfer; Polina German
err分享
err收藏
Toward a Quantitative Understanding of Aficamten Clinical Pharmacology: Population Pharmacokinetic Modeling迈向对Aficamten临床药理学定量理解：群体药代动力学建模
errcpt pharmacometrics systems pharmacology
IF0
err2025-08-17
err0
errOAAI
errDonghong Xu; Hanbin Li; Stephen B. Heitner; Daniel L. Jacoby; Stuart Kupfer; Polina German; Justin Lutz
err分享
err收藏
Serum magnesium and outcomes in heart failure with reduced ejection fraction: the GALACTIC-HF trial血清镁与射血分数降低的心力衰竭的结局：GALACTIC-HF试验
errEUROPEAN HEART JOURNAL
IF35.6
err2025-08-01
err1
errOAAI
errChimura, Misato; Docherty, Kieran F.; Jhund, Pardeep S.; Yang, Mingming; Ono, Ryohei; Henderson, Alasdair D.; Metra, Marco; Liu, Genzhou; Divanji, Punag H.; Heitner, Stephen B.; Kupfer, Stuart; Malik, Fady, I; Felker, G. Michael; Solomon, Scott D.; Teerlink, John R.; McMurray, John J., V
err分享
err收藏
Aficamten Treatment for Symptomatic Obstructive Hypertrophic CardiomyopathyAficamten 治疗：有症状性梗阻性肥厚型心肌病
errjacc heart failure
IF0
err2025-06-19
err0
PREAI
errSara Saberi; Theodore P. Abraham; Lubna Choudhury; Roberto Barriales-Villa; Perry M. Elliott; Michael E. Nassif; Artur Oreziak; Anjali T. Owens; Albree Tower-Rader; Florian Rader; Pablo Garcia-Pavia; Iacopo Olivotto; Caroline J. Coats; Michael A. Fifer; Mark V. Sherrid; Scott D. Solomon; Hugh Watkins; Stephen B. Heitner; Daniel L. Jacoby; Stuart Kupfer; Ahmad Masri
err分享
err收藏
Reply to: Correction to external evaluation of a commercial artificial intelligence-augmented digital auscultation platform in valvular heart disease detection using echocardiography as reference standard回复：针对商业人工智能增强型数字听诊平台的体外评估在瓣膜性心脏病检测中的修正（以超声心动图作为参考标准）
errINTERNATIONAL JOURNAL OF CARDIOLOGY
IF3.2
err2025-05-15
err0
PREAI
errRoquemen-Echeverri, Valentina; Jacobs, Peter G.; Shalen, Evan F.; Schulman, Peter M.; Heitner, Stephen B.; Denfeld, Quin; Wilson, Bethany; Halvorson, John; Scott, Daniel; Murillo, Tomas Londono; Mosquera-Lopez, Clara
err分享
err收藏
Efficacy of aficamten in patients with obstructive hypertrophic cardiomyopathy and mild symptoms: results from the SEQUOIA-HCM trial阿菲坎坦在梗阻性肥厚型心肌病伴轻度症状患者中的疗效：SEQUOIA-HCM试验结果
errEUROPEAN HEART JOURNAL
IF35.6
err2025-05-01
err2
errOAAI
errMaron, Martin S.; Gimeno, Juan Ramon; Veselka, Josef; Barriales-Villa, Roberto; Claggett, Brian L.; Coats, Caroline J.; Hegde, Sheila M.; Januzzi, James L.; Kulac, Ian J.; Masri, Ahmad; Nassif, Michael E.; Spertus, John A.; Jacoby, Daniel L.; Heitner, Stephen B.; Kupfer, Stuart; Malik, Fady, I; Wohltman, Amy; Olivotto, Iacopo
err分享
err收藏
Clinical Evaluation of the Effect of Aficamten on QT/QTc Interval in Healthy Participants健康受试者中Aficamten对QT/QTc间期影响的临床评估
errCTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
err2025-04-08
err0
errOAAI
errMaharao, Neha; Xu, Donghong; Simkins, Tyrell J.; Bowles, Owen; Liu, Genzhou; Benattia, Youcef; Griffith, Adrienne; Heitner, Stephen B.; Kupfer, Stuart; German, Polina
err分享
err收藏
Concomitant Aficamten and Disopyramide in Symptomatic Obstructive Hypertrophic Cardiomyopathy阿菲坎坦与丙吡胺联用治疗症状性梗阻性肥厚型心肌病
errjacc heart failure
IF0
err2025-04-02
err0
errOAAI
errAhmad Masri; Martin S. Maron; Theodore P. Abraham; Michael E. Nassif; Roberto Barriales-Villa; Ozlem Bilen; Caroline J. Coats; Perry Elliott; Pablo Garcia-Pavia; Daniele Massera; Iacopo Olivotto; Artur Oreziak; Anjali Tiku Owens; Sara Saberi; Scott D. Solomon; Albree Tower-Rader; Stephen B. Heitner; Daniel L. Jacoby; Chiara Melloni; Jenny Wei; Mark V. Sherrid
err分享
err收藏
External evaluation of a commercial artificial intelligence-augmented digital auscultation platform in valvular heart disease detection using echocardiography as reference standard
errINTERNATIONAL JOURNAL OF CARDIOLOGY
IF3.2
err2025-01-01
err1
PREAI
errRoquemen-Echeverri, Valentina; Jacobs, Peter G.; Shalen, Evan F.; Schulman, Peter M.; Heitner, Stephen B.; Denfeld, Quin; Wilson, Bethany; Halvorson, John; Scott, Daniel; Londono-Murillo, Tomas; Mosquera-Lopez, Clara
err分享
err收藏
Efficacy and Safety of Omecamtiv Mecarbil in Heart Failure with Reduced Ejection Fraction According to Age: the GALACTIC-HF Trial奥马曲拉在射血分数降低的心力衰竭中的有效性与安全性：按年龄划分——GALACTIC-HF试验
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errLu, Henri; Claggett, Brian; Felker, Gary; McMurray, John; Teerlink, John; Metra, Marco; Heitner, Stephen; Diaz, Rafael; Malik, Fady; Vaduganathan, Muthiah; Solomon, Scott
err分享
err收藏
Efficacy and Safety of Aficamten in Patients Guideline-Eligible for Septal Reduction Therapy in the FOREST-HCM TrialAficamten在FOREST-HCM试验中，对符合室间隔减容治疗指南适应证患者的疗效与安全性
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errMasri, Ahmad; Choudhury, Lubna; Garcia-Pavia, Pablo; Abraham, Theodore; Barriales-Villa, Roberto; Bilen, Ozlem; Elliott, Perry; Hagege, Albert; Nagueh, Sherif; Naidu, Srihari; Nassif, Michael; Olivotto, Iacopo; Oreziak, Artur; Owens, Anjali; Wever-Pinzon, Omar; Rader, Albree Tower; Heitner, Stephen; Kupfer, Stuart; Malik, Fady; Melloni, Chiara; Meng, Lixin; Wei, Jenny; Saberi, Sara
err分享
err收藏
Effect of the Cardiac Myosin Activator Omecamtiv Mecarbil on Risk of Ventricular Arrhythmias in Heart Failure with Reduced Ejection Fraction: the GALACTIC-HF Trial心室心律失常风险中，心肌肌球蛋白激活剂Omecamtiv Mecarbil的影响：GALACTIC-HF试验
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errFoa, Alberto; Vaduganathan, Muthiah; Claggett, Brian; Mani, Govini; Diaz, Rafael; Malik, Fady; Heitner, Stephen; Felker, Gary; Metra, Marco; McMurray, John; Teerlink, John; Solomon, Scott
err分享
err收藏
Efficacy and Safety of Aficamten in Symptomatic Nonobstructive Hypertrophic Cardiomyopathy: Results From the REDWOOD-HCM Trial, Cohort 4Aficamten在症状性非梗阻性肥厚型心肌病中的疗效和安全性: 来自REDWOOD-HCM试验的结果，队列4
errJOURNAL OF CARDIAC FAILURE
IF8.2
err2024-11-01
err7
errOAAI
errMasri, Ahmad; Sherrid, Mark, V; Abraham, Theodore p.; Choudhury, Lubna; Garcia-pavia, Pablo; Kramer, Christopher M.; Barriales-villa, Roberto; Owens, Anjali T.; Rader, Florian; Nagueh, Sherif F.; Olivotto, Iacopo; Saberi, Sara; Tower-rader, Albree; Wong, Timothy c.; Coats, Caroline j.; Watkins, Hugh; Fifer, Michael a.; Solomon, Scott d.; Heitner, Stephen b.; Jacoby, Daniel l.; Kupfer, Stuart; Malik, Fady, I; Meng, Lisa; Sohn, Regina l.; Wohltman, Amy; Maron, Martins S.
err分享
err收藏
Aficamten and Cardiopulmonary Exercise Test Performance: A Substudy of the SEQUOIA-HCM Randomized Clinical Trial
errJAMA CARDIOLOGY
IF14.1
err2024-11-01
err1
PREAI
errLee, Matthew M. Y.; Masri, Ahmad; Nassif, Michael E.; Barriales-Villa, Roberto; Abraham, Theodore P.; Claggett, Brian L.; Coats, Caroline J.; Gimeno, Juan Ramon; Kulac, Ian J.; Landsteiner, Isabela; Ma, Changsheng; Maron, Martin S.; Olivotto, Iacopo; Owens, Anjali T.; Solomon, Scott D.; Veselka, Josef; Jacoby, Daniel L.; Heitner, Stephen B.; Kupfer, Stuart; Malik, Fady I.; Meng, Lisa; Wohltman, Amy; Lewis, Gregory D.
err分享
err收藏

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