Michael P. McDonald - Publications, H-index & Citations

Michael P. McDonald

University of Tennessee Health Science Center

43H指数

88论文数

6.8K被引数

收录论文 36

发表时间

Crosstalk between DNA damage and cGAS-STING immune pathway drives neuroinflammation and dopaminergic neurodegeneration in Parkinson’s disease DNA损伤与cGAS-STING免疫通路之间的串扰驱动帕金森病中的神经炎症和多巴胺能神经变性。

brain behavior and immunity

IF0

2025-07-31

PREAI

Sazzad Khan; David F. Delotterie; Jianfeng Xiao; Ramasamy Thangavel; Roderick Hori; James Koprich; Stephen E. Alway; Michael P. McDonald; Mohammad Moshahid Khan

Gene Therapy Targeting GD3 Synthase Protects Against MPTP-Induced Parkinsonism and Executive Dysfunction 靶向GD3合成酶的基因疗法可对抗MPTP诱导的帕金森病和执行功能障碍

EUROPEAN JOURNAL OF NEUROSCIENCE

IF2.4

2025-03-16

PREAI

Maiti, Panchanan; Xue, Yi; Rex, Tonia S.; Mcdonald, Michael P.

ER stress associated TXNIP-NLRP3 inflammasome activation in hippocampus of human Alzheimer's disease 人类阿尔茨海默病海马ER应激相关TXNIP-NLRP3炎症小体激活

NEUROCHEMISTRY INTERNATIONAL

IF4

2021-09-01

OAAI

Ismael, Saifudeen; Wajidunnisa; Sakata, Kazuko; McDonald, Michael P.; Liao, Francesca-Fang; Ishrat, Tauheed

Thioredoxin interacting protein regulates age-associated neuroinflammation

NEUROBIOLOGY OF DISEASE

IF5.6

2021-08-01

OAAI

Ismael, Saifudeen; Nasoohi, Sanaz; Li, Lexiao; Aslam, Khurram S.; Khan, Mohammad Moshahid; El-Remessy, Azza B.; McDonald, Michael P.; Liao, Francesca-Fang; Ishrat, Tauheed

Alterations in the Gut-Microbial-Inflammasome-Brain Axis in a Mouse Model of Alzheimer's Disease 阿尔茨海默氏病小鼠模型中肠道-微生物-炎症小体-脑轴的变化

CELLS

IF5.2

2021-04-01

OAAI

Shukla, Pradeep K.; Delotterie, David F.; Xiao, Jianfeng; Pierre, Joseph F.; Rao, RadhaKrishna; McDonald, Michael P.; Khan, Mohammad Moshahid

Thioredoxin-Interacting Protein (TXNIP) Associated NLRP3 Inflammasome Activation in Human Alzheimer's Disease Brain

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2019-03-12

OAAI

Li, Lexiao; Ismael, Saifudeen; Nasoohi, Sanaz; Sakata, Kazuko; Liao, Francesca-Fang; McDonald, Michael P.; Ishrat, Tauheed

In utero exposure to fine particulate matter results in an altered neuroimmune phenotype in adult mice

ENVIRONMENTAL POLLUTION

IF7.3

2018-10-01

OAAI

Kulas, Joshua A.; Hettwer, Jordan V.; Sohrabi, Mona; Melvin, Justine E.; Manocha, Gunjan D.; Puig, Kendra L.; Gorr, Matthew W.; Tanwar, Vineeta; McDonald, Michael P.; Wold, Loren E.; Combs, Colin K.

Targeted deletion of GD3 synthase protects against MPTP-induced neurodegeneration

GENES BRAIN AND BEHAVIOR

IF2.3

2017-04-18

OAAI

Akkhawattanangkul, Y.; Maiti, P.; Xue, Y.; Aryal, D.; Wetsel, W. C.; Hamilton, D.; Fowler, S. C.; McDonald, M. P.

A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism

MOLECULAR PSYCHIATRY

IF10.1

2016-07-26

OAAI

Wang, B.; Liu, Y.; Huang, L.; Chen, J.; Li, J. J.; Wang, R.; Kim, E.; Chen, Y.; Justicia, C.; Sakata, K.; Chen, H.; Planas, A.; Ostrom, R. S.; Li, W.; Yang, G.; McDonald, M. P.; Chen, R.; Heck, D. H.; Liao, F-F

Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment

MOLECULAR NEURODEGENERATION

IF17.5

2015-06-24

OAAI

Tan, Xing-Lin; Xue, Yue-Qiang; Ma, Tao; Wang, Xiaofang; Li, Jing Jing; Lan, Lubin; Malik, Kafait U.; McDonald, Michael P.; Dopico, Alejandro M.; Liao, Francesca-Fang

Differential proteomic and behavioral effects of long-term voluntary exercise in wild-type and APP-overexpressing transgenics

NEUROBIOLOGY OF DISEASE

IF5.6

2015-06-01

OAAI

Rao, Shailaja Kishan; Ross, Jordan M.; Harrison, Fiona E.; Bernardo, Alexandra; Reiserer, Randall S.; Reiserer, Ronald S.; Mobley, James A.; McDonald, Michael P.

Abnormal vibrissa-related behavior and loss of barrel field inhibitory neurons in 5xFAD transgenics

GENES BRAIN AND BEHAVIOR

IF2.3

2014-04-22

OAAI

Flanigan, T. J.; Xue, Y.; Rao, S. Kishan; Dhanushkodi, A.; McDonald, M. P.

Antioxidants and cognitive training interact to affect oxidative stress and memory in APP/PSEN1 mice

NUTRITIONAL NEUROSCIENCE

IF3.6

2013-07-19

OAAI

Harrison, F. E.; Allard, J.; Bixler, R.; Usoh, C.; Li, L.; May, J. M.; McDonald, M. P.

Brain gangliosides of a transgenic mouse model of Alzheimer's disease with deficiency in GD3-synthase: expression of elevated levels of a cholinergic-specific ganglioside, GT1aα

ASN NEURO

IF3.7

2013-05-30

OAAI

Ariga, Toshio; Itokazu, Yutaka; McDonald, Michael P.; Hirabayashi, Yoshio; Ando, Susumu; Yu, Robert K.

Ganglioside metabolism in a transgenic mouse model of Alzheimer's disease: expression of Chol-1α antigens in the brain

ASN NEURO

IF3.7

2010-10-04

OAAI

Ariga, Toshio; Yanagisawa, Makoto; Wakade, Chandramohan; Ando, Susumu; Buccafusco, Jerry J.; McDonald, Michael P.; Yu, Robert K.

Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2010-02-01

OAAI

Harrison, F. E.; May, J. M.; McDonald, M. P.

Elimination of GD3 synthase improves memory and reduces amyloid-β plaque load in transgenic mice 消除GD3合酶可改善转基因小鼠的记忆并减少淀粉样蛋白-β 斑块负荷

NEUROBIOLOGY OF AGING

IF3.5

2009-11-01

107

PREAI

Bernardo, Alexandra; Harrison, Fiona E.; McCord, Meghan; Zhao, Jiali; Bruchey, Aleksandra; Davies, Sean S.; Roberts, L. Jackson, II; Mathews, Paul M.; Matsuoka, Yasuji; Ariga, Toshio; Yu, Robert K.; Thompson, Rebecca; McDonald, Michael P.

Vitamin C reduces spatial learning deficits in middle-aged and very old APP/PSEN1 transgenic and wild-type mice

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2009-10-01

OAAI

Harrison, F. E.; Hosseini, A. H.; McDonald, M. P.; May, J. M.

Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease - a review

JOURNAL OF LIPID RESEARCH

IF4.1

2008-06-01

305

OAAI