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M

Mark Chaffin

broad institute of mit and harvard
H指数:54
被引数:1.9万

个人简介

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荣誉奖项

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Human adult and pediatric multimodal transcriptomic atlas of progression from pressure-loaded to failing right ventricle

从压力负荷右心室到衰竭右心室的成人和儿童多模态转录组图谱

Nature Cardiovascular Research
IF10.8
2026-10-090
OAAI
Ivan A. Kuznetsov; Kristina Li; Yasmine Guedira; Bridget Simonson; Mark Chaffin; Yonathan T. Aberra; Kenneth C. Bedi; Trace Thome; Yijun Yang; Kirsten Branch; Wencao Zhao; Wenkai Zhu; Wei Zhou; Farid F. Kadyrov; Junedh M. Amrute; Ling Lai; Joanna Griffin; Li Li; Jian Li; Shelley D. Miyamoto; Patrick Ellinor; Kenneth B. Margulies; Kory J. Lavine; Zoltan Arany; Jonathan J. Edwards
Transcriptional profile of the rat cardiovascular system at single-cell resolution

大鼠心血管系统在单细胞分辨率下的转录谱

CELL REPORTS
IF6.9
2025-01-011
OAAI
Arduini, Alessandro; Fleming, Stephen J.; Xiao, Ling; Hall, Amelia W.; Akkad, Amer-Denis; Chaffin, Mark D.; Bendinelli, Kayla J.; Tucker, Nathan R.; Papangeli, Irinna; Mantineo, Helene; Flores-Bringas, Patricio; Babadi, Mehrtash; Stegmann, Christian M.; Garcia-Cardena, Guillermo; Lindsay, Mark E.; Klattenhoff, Carla; Ellinor, Patrick T.
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience (NOV, 10.1038/s41588-024-01975-5, 2024)

全基因组关联研究揭示扩张型心肌病和心肌弹性的机制 (NOV，10.1038/s41588-024-01975-5，2024)

NATURE GENETICS
IF31.8
2024-12-040
OAAI
Jurgens, Sean J.; Raemoe, Joel T.; Kramarenko, Daria R.; Wijdeveld, Leonoor F. J. M.; Haas, Jan; Chaffin, Mark D.; Garnier, Sophie; Gaziano, Liam; Weng, Lu-Chen; Lipov, Alex; Zheng, Sean L.; Henry, Albert; Huffman, Jennifer E.; Challa, Saketh; Ruehle, Frank; Verdugo, Carmen Diaz; Juarez, Christian Krijger; Kany, Shinwan; van Orsouw, Constance A.; Biddinger, Kiran; Poel, Edwin; Elliott, Amanda L.; Wang, Xin; Francis, Catherine; Ruan, Richard; Koyama, Satoshi; Beekman, Leander; Zimmerman, Dominic S.; Deleuze, Jean-Francois; Villard, Eric; Tregouet, David-Alexandre; Isnard, Richard; Boomsma, Dorret I.; de Geus, Eco J. C.; Tadros, Rafik; Pinto, Yigal M.; Wilde, Arthur A. M.; Hottenga, Jouke-Jan; Sinisalo, Juha; Niiranen, Teemu; Walsh, Roddy; Schmidt, Amand F.; Choi, Seung Hoan; Chang, Kyong-Mi; Tsao, Philip S.; Matthews, Paul M.; Ware, James S.; Lumbers, R. Thomas; van der Crabben, Saskia; Laukkanen, Jari; Palotie, Aarno; Amin, Ahmad S.; Charron, Philippe; Meder, Benjamin; Ellinor, Patrick T.; Daly, Mark; Aragam, Krishna G.; Bezzina, Connie R.
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience

全基因组关联研究揭示扩张型心肌病和心肌弹性的机制

NATURE GENETICS
IF31.8
2024-11-211
OAAI
Jurgens, Sean J.; Raemoe, Joel T.; Kramarenko, Daria R.; Wijdeveld, Leonoor F. J. M.; Haas, Jan; Chaffin, Mark D.; Garnier, Sophie; Gaziano, Liam; Weng, Lu-Chen; Lipov, Alex; Zheng, Sean L.; Henry, Albert; Huffman, Jennifer E.; Challa, Saketh; Ruehle, Frank; Verdugo, Carmen Diaz; Krijger Juarez, Christian; Kany, Shinwan; van Orsouw, Constance A.; Biddinger, Kiran; Poel, Edwin; Elliott, Amanda L.; Wang, Xin; Francis, Catherine; Ruan, Richard; Koyama, Satoshi; Beekman, Leander; Zimmerman, Dominic S.; Deleuze, Jean-Francois; Villard, Eric; Tregouet, David-Alexandre; Isnard, Richard; Boomsma, Dorret I.; de Geus, Eco J. C.; Tadros, Rafik; Pinto, Yigal M.; Wilde, Arthur A. M.; Hottenga, Jouke-Jan; Sinisalo, Juha; Niiranen, Teemu; Walsh, Roddy; Schmidt, Amand F.; Choi, Seung Hoan; Chang, Kyong-Mi; Tsao, Philip S.; Matthews, Paul M.; Ware, James S.; Lumbers, R. Thomas; van der Crabben, Saskia; Laukkanen, Jari; Palotie, Aarno; Amin, Ahmad S.; Charron, Philippe; Meder, Benjamin; Ellinor, Patrick T.; Daly, Mark; Aragam, Krishna G.; Bezzina, Connie R.
Rare coding variant analysis for human diseases across biobanks and ancestries
NATURE GENETICS
IF31.8
2024-08-291
PRE
Jurgens, Sean J.; Wang, Xin; Choi, Seung Hoan; Weng, Lu-Chen; Koyama, Satoshi; Pirruccello, James P.; Nguyen, Trang; Smadbeck, Patrick; Jang, Dongkeun; Chaffin, Mark; Walsh, Roddy; Roselli, Carolina; Elliott, Amanda L.; Wijdeveld, Leonoor F. J. M.; Biddinger, Kiran J.; Kany, Shinwan; Ramo, Joel T.; Natarajan, Pradeep; Aragam, Krishna G.; Flannick, Jason; Burtt, Noel P.; Bezzina, Connie R.; Lubitz, Steven A.; Lunetta, Kathryn L.; Ellinor, Patrick T.
Distinct Plasma Extracellular Vesicle Transcriptomes in Acute Decompensated Heart Failure Subtypes: A Liquid Biopsy Approach

急性失代偿性心力衰竭亚型中不同的血浆细胞外囊泡转录组: 液体活检方法

CIRCULATION
IF38.6
2024-04-023
PRE
Gokulnath, Priyanka; Spanos, Michail; Lehmann, H. Immo; Sheng, Quanhu; Rodosthenous, Rodosthenis; Chaffin, Mark; Varrias, Dimitrios; Chatterjee, Emeli; Hutchins, Elizabeth; Li, Guoping; Daaboul, George; Rana, Farhan; Wang, Ashley Mingyi; Van Keuren-Jensen, Kendall; Ellinor, Patrick T.; Shah, Ravi; Das, Saumya
Transfer learning enables predictions in network biology

迁移学习使网络生物学中的预测成为可能

Nature
IF48.5
2023-05-310
PRE
Christina V. Theodoris; Ling Xiao; Anant Chopra; Mark D. Chaffin; Zeina R. Al Sayed; Matthew C. Hill; Helene Mantineo; Elizabeth M. Brydon; Zexian Zeng; X. Shirley Liu; Patrick T. Ellinor
Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease
CIRCULATION-GENOMIC AND PRECISION MEDICINE
IF5.5
2022-12-019
OA
Khera, Amit, V; Wang, Minxian; Chaffin, Mark; Emdin, Connor A.; Samani, Nilesh J.; Schunkert, Heribert; Watkins, Hugh; McPherson, Ruth; Erdmann, Jeanette; Elosua, Roberto; Boerwinkle, Eric; Ardissino, Diego; Butterworth, Adam S.; Di Angelantonio, Emanuele; Naheed, Aliya; Danesh, John; Chowdhury, Rajiv; Krumholz, Harlan M.; Sheu, Wayne H-H; Rich, Stephen S.; Rotter, Jerome, I; Chen, Yii-der Ida; Gabriel, Stacey; Lander, Eric S.; Saleheen, Danish; Kathiresan, Sekar
Aortic Cellular Diversity and Quantitative Genome-Wide Association Study Trait Prioritization Through Single-Nuclear RNA Sequencing of the Aneurysmal Human Aorta
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
2022-11-0119
OA
Chou, Elizabeth L.; Chaffin, Mark; Simonson, Bridget; Pirruccello, James P.; Akkad, Amer-Denis; Nekoui, Mahan; Cardenas, Christian Lacks Lino; Bedi, Kenneth C., Jr.; Nash, Craig; Juric, Dejan; Stone, James R.; Isselbacher, Eric M.; Margulies, Kenneth B.; Klattenhoff, Carla; Ellinor, Patrick T.; Lindsay, Mark E.
Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy

人类扩张型和肥厚型心肌病的单核谱分析

Nature
IF48.5
2022-06-220
PRE
Mark Chaffin; Irinna Papangeli; Bridget Simonson; Amer-Denis Akkad; Matthew C. Hill; Alessandro Arduini; Stephen J. Fleming; Michelle Melanson; Sikander Hayat; Maria Kost-Alimova; Ondine Atwa; Jiangchuan Ye; Kenneth C. Bedi; Matthias Nahrendorf; Virendar K. Kaushik; Christian M. Stegmann; Kenneth B. Margulies; Nathan R. Tucker; Patrick T. Ellinor
Genetic analysis of right heart structure and function in 40,000 people
NATURE GENETICS
IF31.8
2022-06-1340
OA
Pirruccello, James P.; Di Achille, Paolo; Nauffal, Victor; Nekoui, Mahan; Friedman, Samuel F.; Klarqvist, Marcus D. R.; Chaffin, Mark D.; Weng, Lu-Chen; Cunningham, Jonathan W.; Khurshid, Shaan; Roselli, Carolina; Lin, Honghuang; Koyama, Satoshi; Ito, Kaoru; Kamatani, Yoichiro; Komuro, Issei; Jurgens, Sean J.; Benjamin, Emelia J.; Batra, Puneet; Natarajan, Pradeep; Ng, Kenney; Hoffmann, Udo; Lubitz, Steven A.; Ho, Jennifer E.; Lindsay, Mark E.; Philippakiss, Anthony A.; Ellinor, Patrick T.
Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank

英国生物库中200,000个人的心脏代谢疾病和性状的罕见遗传变异分析

NATURE GENETICS
IF31.8
2022-02-1778
OAAI
Jurgens, Sean J.; Choi, Seung Hoan; Morrill, Valerie N.; Chaffin, Mark; Pirruccello, James P.; Halford, Jennifer L.; Weng, Lu-Chen; Nauffal, Victor; Roselli, Carolina; Hall, Amelia W.; Oetjens, Matthew T.; Lagerman, Braxton; VanMaanen, David P.; Center, Regeneron Genetics; Aragam, Krishna G.; Lunetta, Kathryn L.; Haggerty, Christopher M.; Lubitz, Steven A.; Ellinor, Patrick T.

研究方向

暂未获取到该数据
P
Patrick T. Ellinor
H 指数:137论文数:994被引数:10.4万
K
Krishna G. Aragam
H 指数:43论文数:166被引数:1.2万
S
Steven A. Lubitz
H 指数:99论文数:549被引数:5.3万
S
Seung Hoan Choi
H 指数:54论文数:223被引数:2.0万
C
Carolina Roselli
H 指数:49论文数:137被引数:1.7万
A
Amit V. Khera
H 指数:64论文数:303被引数:3.0万
P
Pradeep Natarajan
H 指数:92论文数:935被引数:4.9万
S
Sekar Kathiresan
H 指数:133论文数:438被引数:11.4万
L
Lu‐Chen Weng
H 指数:51论文数:159被引数:1.2万
J
Jerome I. Rotter
H 指数:176论文数:1,853被引数:15.9万