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J

Jukka-Pekka Mecklin

jyväskylä university
H指数:98
被引数:4.6万

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Epithelial interferon-stimulated gene programs modulate chemotherapy sensitivity in colorectal cancer via EPSTI1

上皮干扰素刺激基因程序通过EPSTI1调节结直肠癌的化疗敏感性

Oncogene
IF7.3
2026-08-210
OA
Erdogan Pekcan Erkan; Emmi Hämäläinen; Julia Kolikova; Tiia Nikupaavola; Karishma Sajnani; Kornelia Kuc; Kalle Ojala; Meiju Kukkonen; Ismaïl Hermelo; Antti Kurttila; Selja Koskensalo; Timo Tarvainen; Alli Leppä; Ilona Keränen; Carola Haapamäki; Essi Karjalainen; Monika Carpelan-Holmström; Laura Renkonen-Sinisalo; Laura Koskenvuo; Pauli Puolakkainen; Jukka-Pekka Mecklin; Juha P. Väyrynen; Elina Virolainen; Matti Nykter; Lauri A. Aaltonen; Alfonso Urbanucci; Anna Lepistö; Ari Ristimäki; Toni T. Seppälä
Tumor-Infiltrating Basophils Are Associated With Improved Prognosis in Colorectal Cancer

肿瘤浸润的嗜碱性粒细胞与结直肠癌改善的预后相关

Laboratory Investigation
IF4.2
2026-07-090
PRE
Oskari Rahkola; Henna Karjalainen; Ville K. Äijälä; Meeri Kastinen; Vilja V. Tapiainen; Hanna Elomaa; Onni Sirkiä; Vesa-Matti Pohjanen; Maarit Ahtiainen; Olli Helminen; Taneli T. Mattila; Outi Lindgren; Erkki-Ville Wirta; Jukka Rintala; Sanna Meriläinen; Juha Saarnio; Tero Rautio; Toni T. Seppälä; Jan Böhm; Jukka-Pekka Mecklin
Urothelium marker UPK2 identifies aggressive colorectal cancers with distinct molecular and histological features

尿路上皮标志物UPK2识别具有独特分子和形态学特征的侵袭性结直肠癌

British Journal of Cancer
IF6.8
2025-12-110
OAAI
Ville K. Äijälä; Jouni Härkönen; Päivi Sirniö; Tuomo Mantere; Hanna Elomaa; Onni Sirkiä; Akseli Kehusmaa; Henna Karjalainen; Meeri Kastinen; Vilja V. Tapiainen; Maarit Ahtiainen; Olli Helminen; Erkki-Ville Wirta; Jukka Rintala; Sanna Meriläinen; Juha Saarnio; Tero Rautio; Toni T. Seppälä; Jan Böhm; Jukka-Pekka Mecklin; Anne Tuomisto; Markus J. Mäkinen; Juha P. Väyrynen
PTEN status, tumor immune microenvironment, and survival in colorectal cancer

PTEN状态、肿瘤免疫微环境及结直肠癌中的生存情况

Virchows Archiv
IF3.1
2025-11-180
OAAI
Joni Karjalainen; Onni Sirkiä; Päivi Sirniö; Hanna Elomaa; Henna Karjalainen; Ville K. Äijälä; Meeri Kastinen; Vilja V. Tapiainen; Vesa-Matti Pohjanen; Maarit Ahtiainen; Olli Helminen; Erkki-Ville Wirta; Taneli T. Mattila; Outi Lindgren; Jukka Rintala; Sanna Meriläinen; Juha Saarnio; Tero Rautio; Toni T. Seppälä; Jan Böhm; Jukka-Pekka Mecklin; Anne Tuomisto; Markus J. Mäkinen; Juha P. Väyrynen
Characteristics and significance of γδ T cells in colorectal cancer

γδ T细胞在结直肠癌中的特征与意义

OncoImmunology
IF6.3
2025-07-280
OA
Henna Karjalainen; Jouni Härkönen; Päivi Sirniö; Hanna Elomaa; Ville K. Äijälä; Meeri Kastinen; Vilja V. Tapiainen; Sara A. Väyrynen; Maarit Ahtiainen; Olli Helminen; Erkki-Ville Wirta; Jukka Rintala; Sanna Meriläinen; Juha Saarnio; Tero Rautio; Toni T. Seppälä; Jan Böhm; Jukka-Pekka Mecklin; Anne Tuomisto; Markus J. Mäkinen; Juha P. Väyrynen
Integrating Tumor Intraepithelial CD8+ and Stromal FOXP3+ T-Cell Densities as an Enhanced Immune Prognostic Index in Colorectal Cancer

整合肿瘤上皮内CD8+和间质FOXP3+ T细胞密度作为结直肠癌的增强型免疫预后指数

Laboratory Investigation
IF4.2
2025-07-170
OAAI
Anne Tuomisto; Päivi Sirniö; Hanna Elomaa; Henna Karjalainen; Ville K. Äijälä; Meeri Kastinen; Vilja V. Tapiainen; Maarit Ahtiainen; Olli Helminen; Erkki-Ville Wirta; Jukka Rintala; Sanna Meriläinen; Juha Saarnio; Tero Rautio; Toni T. Seppälä; Jan Böhm; Jukka-Pekka Mecklin; Markus J. Mäkinen; Juha P. Väyrynen
Associations of mucinous differentiation and mucin expression with immune cell infiltration and prognosis in colorectal adenocarcinoma
BRITISH JOURNAL OF CANCER
IF6.8
2025-02-180
OA
Elomaa, Hanna; Tarkiainen, Vilma; Aijala, Ville K.; Sirnio, Paivi; Ahtiainen, Maarit; Sirkia, Onni; Karjalainen, Henna; Kastinen, Meeri; Tapiainen, Vilja V.; Rintala, Jukka; Merilainen, Sanna; Saarnio, Juha; Rautio, Tero; Tuomisto, Anne; Helminen, Olli; Wirta, Erkki-Ville; Seppala, Toni T.; Bohm, Jan; Makinen, Markus J.; Mecklin, Jukka-Pekka; Vayrynen, Juha P.
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

包括254,000多名东亚和欧洲后代的精细图谱分析确定了136个推定的结直肠癌易感基因

NATURE COMMUNICATIONS
IF15.7
2024-04-264
OAAI
Chen, Zhishan; Guo, Xingyi; Tao, Ran; Huyghe, Jeroen R.; Law, Philip J.; Fernandez-Rozadilla, Ceres; Ping, Jie; Jia, Guochong; Long, Jirong; Li, Chao; Shen, Quanhu; Xie, Yuhan; Timofeeva, Maria N.; Thomas, Minta; Schmit, Stephanie L.; Diez-Obrero, Virginia; Devall, Matthew; Moratalla-Navarro, Ferran; Fernandez-Tajes, Juan; Palles, Claire; Sherwood, Kitty; Briggs, Sarah E. W.; Svinti, Victoria; Donnelly, Kevin; Farrington, Susan M.; Blackmur, James; Vaughan-Shaw, Peter G.; Shu, Xiao-Ou; Lu, Yingchang; Broderick, Peter; Studd, James; Harrison, Tabitha A.; Conti, David V.; Schumacher, Fredrick R.; Melas, Marilena; Rennert, Gad; Obon-Santacana, Mireia; Martin-Sanchez, Vicente; Oh, Jae Hwan; Kim, Jeongseon; Jee, Sun Ha; Jung, Keum Ji; Kweon, Sun-Seog; Shin, Min-Ho; Shin, Aesun; Ahn, Yoon-Ok; Kim, Dong-Hyun; Oze, Isao; Wen, Wanqing; Matsuo, Keitaro; Matsuda, Koichi; Tanikawa, Chizu; Ren, Zefang; Gao, Yu-Tang; Jia, Wei-Hua; Hopper, John L.; Jenkins, Mark A.; Win, Aung Ko; Pai, Rish K.; Figueiredo, Jane C.; Haile, Robert W.; Gallinger, Steven; Woods, Michael O.; Newcomb, Polly A.; Duggan, David; Cheadle, Jeremy P.; Kaplan, Richard; Kerr, Rachel; Kerr, David; Kirac, Iva; Bohm, Jan; Mecklin, Jukka-Pekka; Jousilahti, Pekka; Knekt, Paul; Aaltonen, Lauri A.; Rissanen, Harri; Pukkala, Eero; Eriksson, Johan G.; Cajuso, Tatiana; Hanninen, Ulrika; Kondelin, Johanna; Palin, Kimmo; Tanskanen, Tomas; Renkonen-Sinisalo, Laura; Mannisto, Satu; Albanes, Demetrius; Weinstein, Stephanie J.; Ruiz-Narvaez, Edward; Palmer, Julie R.; Buchanan, Daniel D.; Platz, Elizabeth A.; Visvanathan, Kala; Ulrich, Cornelia M.; Siegel, Erin; Brezina, Stefanie; Gsur, Andrea; Campbell, Peter T.; Chang-Claude, Jenny; Hoffmeister, Michael; Brenner, Hermann; Slattery, Martha L.; Potter, John D.; Tsilidis, Kostas K.; Schulze, Matthias B.; Gunter, Marc J.; Murphy, Neil; Castells, Antoni; Castellvi-Bel, Sergi; Moreira, Leticia; Arndt, Volker; Shcherbina, Anna; Bishop, D. Timothy; Giles, Graham G.; Southey, Melissa C.; Idos, Gregory E.; McDonnell, Kevin J.; Abu-Ful, Zomoroda; Greenson, Joel K.; Shulman, Katerina; Lejbkowicz, Flavio; Offit, Kenneth; Su, Yu-Ru; Steinfelder, Robert; Keku, Temitope O.; van Guelpen, Bethany; Hudson, Thomas J.; Hampel, Heather; Pearlman, Rachel; Berndt, Sonja I.; Hayes, Richard B.; Martinez, Marie Elena; Thomas, Sushma S.; Pharoah, Paul D. P.; Larsson, Susanna C.; Yen, Yun; Lenz, Heinz-Josef; White, Emily; Li, Li; Doheny, Kimberly F.; Pugh, Elizabeth; Shelford, Tameka; Chan, Andrew T.; Cruz-Correa, Marcia; Lindblom, Annika; Hunter, David J.; Joshi, Amit D.; Schafmayer, Clemens; Scacheri, Peter C.; Kundaje, Anshul; Schoen, Robert E.; Hampe, Jochen; Stadler, Zsofia K.; Vodicka, Pavel; Vodickova, Ludmila; Vymetalkova, Veronika; Edlund, Christopher K.; Gauderman, W. James; Shibata, David; Toland, Amanda; Markowitz, Sanford; Kim, Andre; Chanock, Stephen J.; van Duijnhoven, Franzel; Feskens, Edith J. M.; Sakoda, Lori C.; Gago-Dominguez, Manuela; Wolk, Alicja; Pardini, Barbara; FitzGerald, Liesel M.; Lee, Soo Chin; Ogino, Shuji; Bien, Stephanie A.; Kooperberg, Charles; Li, Christopher I.; Lin, Yi; Prentice, Ross; Qu, Conghui; Bezieau, Stephane; Yamaji, Taiki; Sawada, Norie; Iwasaki, Motoki; Le Marchand, Loic; Wu, Anna H.; Qu, Chenxu; McNeil, Caroline E.; Coetzee, Gerhard; Hayward, Caroline; Deary, Ian J.; Harris, Sarah E.; Theodoratou, Evropi; Reid, Stuart; Walker, Marion; Ooi, Li Yin; Lau, Ken S.; Zhao, Hongyu; Hsu, Li; Cai, Qiuyin; Dunlop, Malcolm G.; Gruber, Stephen B.; Houlston, Richard S.; Moreno, Victor; Casey, Graham; Peters, Ulrike; Tomlinson, Ian; Zheng, Wei
Identification of DHX40 as a candidate susceptibility gene for colorectal and hematological neoplasia

鉴定DHX40作为结直肠和血液肿瘤的候选易感基因

LEUKEMIA
IF13.4
2023-09-111
OAAI
Olkinuora, Alisa; Nieminen, Taina T.; Douglas, Suvi; Kauppinen, Anni; Kontro, Mika; Vaananen, Juho; Kankainen, Matti; Ristimaki, Ari; Makinen, Markus; Lahermo, Paivi; Heckman, Caroline; Saarela, Janna; Salonen, Milla; Lepisto, Anna; Jarvinen, Heikki; Mecklin, Jukka-Pekka; Kilpivaara, Outi; Wartiovaara-Kautto, Ulla; Porkka, Kimmo; Peltomaki, Paeivi

研究方向

暂未获取到该数据
L
Lauri A. Aaltonen
H 指数:119论文数:665被引数:7.1万
H
Heikki Järvinen
H 指数:85论文数:353被引数:3.1万
T
Toni T. Seppälä
H 指数:52论文数:397被引数:1.0万
L
Laura Renkonen‐Sinisalo
H 指数:41论文数:142被引数:9,379
J
Jan Böhm
H 指数:31论文数:171被引数:3,053
P
Païvi Peltomäki
H 指数:77论文数:294被引数:3.3万
M
Maarit Ahtiainen
H 指数:18论文数:121被引数:1,234
A
Ari Ristimäki
H 指数:69论文数:392被引数:1.7万
A
Anna Lepistö
H 指数:40论文数:193被引数:5,244
S
Sari Tuupanen
H 指数:28论文数:137被引数:4,080