未登录 分享 收藏
Mapping the observable IBDverse: Using massive-scale single-cell RNA sequencing of gut and blood samples to nominate genes, cell types and pathways driving IBD susceptibility Harris, B.; Alegbe, T.; Ramirez-Navaro, L.; Tutert, M.; Krzak, M.; Ozols, M.; Ghouraba, M.; Strickland, M.; Wana, N.; Hu, M.; Ostermayer, J.; Mcintyre, R.; Martin, C. Cotobal; Fachal, L.; Jones, G. R.; Raine, T.; Anderson, C. 分享 收藏
Inflammation-associated monocytes express ACOD1 to curtail inflammatory behaviour in IBD and experimental colitis Jones, G. R.; Drury, B.; Hegarty, L.; Alegbe, T.; Krzak, M.; Raine, T.; Byrne, A.; Anderson, C.; Ho, G. T.; Bain, C. 分享 收藏
分享 收藏
Effects of psoriasis and psoralen exposure on the somatic mutation landscape of the skin Olafsson, Sigurgeir; Rodriguez, Elke; Lawson, Andrew R. J.; Abascal, Federico; Huber, Axel Rosendahl; Suembuel, Melike; Jones, Philip H.; Gerdes, Sascha; Martincorena, Inigo; Weidinger, Stephan; Campbell, Peter J.; Anderson, Carl A. 分享 收藏
Baseline Expression of Immune Gene Modules in Blood is Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease Patients Bai, Benjamin Y. H.; Reppell, Mark; Smaoui, Nizar; Waring, Jeffrey F.; Pivorunas, Valerie; Guay, Heath; Lin, Simeng; Chanchlani, Neil; Bewshea, Claire; Goodhand, James R.; Kennedy, Nicholas A.; Ahmad, Tariq; Anderson, Carl A. 分享 收藏
Genomic diagnosis and care co-ordination for monogenic inflammatory bowel disease in children and adults: consensus guideline on behalf of the British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition Kammermeier, Jochen; Lamb, Christopher A.; Jones, Kelsey D. J.; Anderson, Carl A.; Baple, Emma L.; Bolton, Chrissy; Braggins, Helen; Coulter, Tanya, I; Gilmour, Kimberly C.; Gregory, Vicki; Hambleton, Sophie; Hartley, David; Hawthorne, A. Barney; Hearn, Sarah; Laurence, Arian; Parkes, Miles; Russell, Richard K.; Speight, R. Alexander; Travis, Simon; Wilson, David C.; Uhlig, Holm H. 分享 收藏
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility 大规模测序鉴定与克罗恩病易感性相关的多个基因和罕见变异 Sazonovs, Aleksejs; Stevens, Christine R.; Venkataraman, Guhan R.; Yuan, Kai; Avila, Brandon; Abreu, Maria T.; Ahmad, Tariq; Allez, Matthieu; Ananthakrishnan, Ashwin N.; Atzmon, Gil; Baras, Aris; Barrett, Jeffrey C.; Barzilai, Nir; Beaugerie, Laurent; Beecham, Ashley; Bernstein, Charles N.; Bitton, Alain; Bokemeyer, Bernd; Chan, Andrew; Chung, Daniel; Cleynen, Isabelle; Cosnes, Jacques; Cutler, David J.; Daly, Allan; Damas, Oriana M.; Datta, Lisa W.; Dawany, Noor; Devoto, Marcella; Dodge, Sheila; Ellinghaus, Eva; Fachal, Laura; Farkkila, Martti; Faubion, William; Ferreira, Manuel; Franchimont, Denis; Gabriel, Stacey B.; Ge, Tian; Georges, Michel; Gettler, Kyle; Giri, Mamta; Glaser, Benjamin; Goerg, Siegfried; Goyette, Philippe; Graham, Daniel; Hamalainen, Eija; Haritunians, Talin; Heap, Graham A.; Hiltunen, Mikko; Hoeppner, Marc; Horowitz, Julie E.; Irving, Peter; Iyer, Vivek; Jalas, Chaim; Kelsen, Judith; Khalili, Hamed; Kirschner, Barbara S.; Kontula, Kimmo; Koskela, Jukka T.; Kugathasan, Subra; Kupcinskas, Juozas; Lamb, Christopher A.; Laudes, Matthias; Levesque, Chloe; Levine, Adam P.; Lewis, James D.; Liefferinckx, Claire; Loescher, Britt-Sabina; Louis, Edouard; Mansfield, John; May, Sandra; McCauley, Jacob L.; Mengesha, Emebet; Mni, Myriam; Moayyedi, Paul; Moran, Christopher J.; Newberry, Rodney D.; O'Charoen, Sirimon; Okou, David T.; Oldenburg, Bas; Ostrer, Harry; Palotie, Aarno; Paquette, Jean; Pekow, Joel; Peter, Inga; Pierik, Marieke J.; Ponsioen, Cyriel Y.; Pontikos, Nikolas; Prescott, Natalie; Pulver, Ann E.; Rahmouni, Souad; Rice, Daniel L.; Saavalainen, Paivi; Sands, Bruce; Sartor, R. Balfour; Schiff, Elena R.; Schreiber, Stefan; Schumm, L. Philip; Segal, Anthony W.; Seksik, Philippe; Shawky, Rasha; Sheikh, Shehzad Z.; Silverberg, Mark S.; Simmons, Alison; Skeiceviciene, Jurgita; Sokol, Harry; Solomonson, Matthew; Somineni, Hari; Sun, Dylan; Targan, Stephan; Turner, Dan; Uhlig, Holm H.; van der Meulen, Andrea E.; Vermeire, Severine; Verstockt, Sare; Voskuil, Michiel D.; Winter, Harland S.; Young, Justine; Duerr, Richard H.; Franke, Andre; Brant, Steven R.; Cho, Judy; Weersma, Rinse K.; Parkes, Miles; Xavier, Ramnik J.; Rivas, Manuel A.; Rioux, John D.; McGovern, Dermot P. B.; Huang, Hailiang; Anderson, Carl A.; Daly, Mark J. 分享 收藏
An Integrated Taxonomy for Monogenic Inflammatory Bowel Disease Bolton, Chrissy; Smillie, Christopher S.; Pandey, Sumeet; Elmentaite, Rasa; Wei, Gabrielle; Argmann, Carmen; Aschenbrenner, Dominik; James, Kylie R.; McGovern, Dermot P. B.; Macchi, Marina; Cho, Judy; Shouval, Dror S.; Kammermeier, Jochen; Koletzko, Sibylle; Bagalopal, Krithika; Capitani, Melania; Cavounidis, Athena; Pires, Elisabete; Weidinger, Carl; McCullagh, James; Arkwright, Peter D.; Haller, Wolfram; Siegmund, Britta; Peters, Lauren; Jostins, Luke; Travis, Simon P. L.; Anderson, Carl A.; Snapper, Scott; Klein, Christoph; Schadt, Eric; Zilbauer, Matthias; Xavier, Ramnik; Teichmann, Sarah; Muise, Aleixo M.; Regev, Aviv; Uhlig, Holm H. 分享 收藏
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders 对53,400例肠易激综合征患者的全基因组分析突出了情绪和焦虑障碍的共同遗传途径 Eijsbouts, Chris; Zhen, Tenghao; Kennedy, Nicholas A.; Bonfiglio, Ferdinando; Anderson, Carl A.; Moutsianas, Loukas; Holliday, Joanne; Shi, Jingchunzi; Shringarpure, Suyash; Voda, Alexandru-loan; Farrugia, Gianrico; Franke, Andre; Huebenthal, Matthias; Abecasis, Goncalo; Zawistowski, Matthew; Skogholt, Anne Heidi; Ness-Jensen, Eivind; Hveem, Kristian; Esko, Tonu; Teder-Laving, Maris; Zhernakova, Alexandra; Camilleri, Michael; Boeckxstaens, Guy; Whorwell, Peter J.; Spiller, Robin; McVean, Gil; D'Amato, Mauro; Jostins, Luke; Parkes, Miles 分享 收藏
分享 收藏
Common and Rare Variant Prediction and Penetrance of IBD in a Large, Multi-ethnic, Health System-based Biobank Cohort Gettler, Kyle; Levantovsky, Rachel; Moscati, Arden; Giri, Mamta; Wu, Yiming; Hsu, Nai-Yun; Chuang, Ling-Shiang; Sazonovs, Aleksejs; Venkateswaran, Suresh; Korie, Ujunwa; Chasteau, Colleen; Duerr, Richard H.; Silverberg, Mark S.; Snapper, Scott B.; Daly, Mark J.; McGovern, Dermot P.; Brant, Steven R.; Rioux, John D.; Kugathasan, Subra; Anderson, Carl A.; Itan, Yuval; Cho, Judy H. 分享 收藏
分享 收藏
HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn's Disease Sazonovs, Aleksejs; Kennedy, Nicholas A.; Moutsianas, Loukas; Heap, Graham A.; Rice, Daniel L.; Reppell, Mark; Bewshea, Claire M.; Chanchlani, Neil; Walker, Gareth J.; Perry, Mandy H.; McDonald, Timothy J.; Lees, Charlie W.; Cummings, J. R. Fraser; Parkes, Miles; Mansfield, John C.; Irving, Peter M.; Barrett, Jeffrey C.; McGovern, Dermot; Goodhand, James R.; Anderson, Carl A.; Ahmad, Tariq 分享 收藏
Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles B细胞池的不完全基因重建有助于麻疹后长期免疫抑制 Petrova, Velislava N.; Sawatsky, Bevan; Han, Alvin X.; Laksono, Brigitta M.; Walz, Lisa; Parker, Edyth; Pieper, Kathrin; Anderson, Carl A.; de Vries, Rory D.; Lanzavecchia, Antonio; Kellam, Paul; von Messling, Veronika; de Swart, Rik L.; Russell, Colin A. 分享 收藏
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population (vol 14, e1007329, 2018) 了解德系犹太人口中克罗恩病和罕见疾病的遗传流行病学 (第14卷，e1007329，2018) Rivas, Manuel A.; Avila, Brandon E.; Koskela, Jukka; Huang, Hailiang; Stevens, Christine; Pirinen, Matti; Haritunians, Talin; Neale, Benjamin M.; Kurki, Mitja; Ganna, Andrea; Graham, Daniel; Glaser, Benjamin; Peter, Inga; Atzmon, Gil; Barzilai, Nir; Levine, Adam P.; Schiff, Elena; Pontikos, Nikolas; Weisburd, Ben; Lek, Monkol; Karczewski, Konrad J.; Bloom, Jonathan; Minikel, Eric V.; Petersen, Britt-Sabina; Beaugerie, Laurent; Seksik, Philippe; Cosnes, Jacques; Schreiber, Stefan; Bokemeyer, Bernd; Bethge, Johannes; Heap, Graham; Ahmad, Tariq; Plagnol, Vincent; Segal, Anthony W.; Targan, Stephan; Turner, Dan; Saavalainen, Paivi; Farkkila, Martti; Kontula, Kimmo; Palotie, Aarno; Brant, Steven R.; Duerr, Richard H.; Silverberg, Mark S.; Rioux, John D.; Weersma, Rinse K.; Franke, Andre; Jostins, Luke; Anderson, Carl A.; Barrett, Jeffrey C.; MacArthur, Daniel G.; Jalas, Chaim; Sokol, Harry; Xavier, Ramnik J.; Pulver, Ann; Cho, Judy H.; McGovern, Dermot P. B.; Daly, Mark J. 分享 收藏
Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System Goode, Elizabeth C.; Clark, Allan B.; Mells, George F.; Srivastava, Brijesh; Spiess, Kelly; Gelson, William T. H.; Trivedi, Palak J.; Lynch, Kate D.; Castren, Edit; Vesterhus, Mette N.; Karlsen, Tom H.; Ji, Sungou; Anderson, Carl A.; Thorburn, Douglas; Hudson, Mark; Heneghan, Michael A.; Aldersley, Mark A.; Bathgate, Andrew; Sandford, Richard N.; Alexander, Graeme J.; Chapman, Roger W.; Walmsley, Martine; Hirschfield, Gideon M.; Rushbrook, Simon M. 分享 收藏
Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease NUDT15基因变异与硫嘌呤诱导的炎症性肠病骨髓抑制的相关性 Walker, Gareth J.; Harrison, James W.; Heap, Graham A.; Voskuil, Michiel D.; Andersen, Vibeke; Anderson, Carl A.; Ananthakrishnan, Ashwin N.; Barrett, Jeffrey C.; Beaugerie, Laurent; Bewshea, Claire M.; Cole, Andy T.; Cummings, Fraser R.; Daly, Mark J.; Ellul, Pierre; Fedorak, Richard N.; Festen, Eleonora A. M.; Florin, Timothy H.; Gaya, Daniel R.; Halfvarson, Jonas; Hart, Ailsa L.; Heerasing, Neel M.; Hendy, Peter; Irving, Peter M.; Jones, Samuel E.; Koskela, Jukka; Lindsay, James O.; Mansfield, John C.; McGovern, Dermot; Parkes, Miles; Pollok, Richard C. G.; Ramakrishnan, Subramaniam; Rampton, David S.; Rivas, Manuel A.; Russell, Richard K.; Schultz, Michael; Sebastian, Shaji; Seksik, Philippe; Singh, Abhey; So, Kenji; Sokol, Harry; Subramaniam, Kavitha; Todd, Anthony; Annese, Vito; Weersma, Rinse K.; Xavier, Ramnik; Ward, Rebecca; Weedon, Michael N.; Goodhand, James R.; Kennedy, Nicholas A.; Ahmad, Tariq; Holden, Arthur L.; Andrews, Jane; Auth, Marcus; Babu, Sathish; Bampton, Peter; Banim, Paul; Barnes, Theresa; Basude, Dharam; Beckly, John; Bell, Andy; Bell, Sally; Bhandari, Pradeep; Bloom, Stuart; Border, Dave; Bredin, Francesca; Brookes, Matthew J.; Brown, Matthew; Calvert, Chris; Campbell, David; Chanchlani, Neil; Chaudhary, Basant; Chaudhary, Rakesh; Chung-Faye, Guy; Colleypriest, Ben; Connor, Susan; Cooney, Rachel; Cooper, Sheldon; Creed, Tom J.; Croft, Nick; Cullen, Sue; D'Amato, Mauro; Dalal, Helen; Daneshmend, Tawfique K.; Das, Debasish; Delaney, Michael; Desilva, Shanika; Dhar, Anjan; Dharmasiri, Suranga; Direkze, Natalie; Dunckley, Paul; Elphick, David; Everett, Simon M.; Feeney, Mark; Fell, John; Foley, Stephen; Franke, Andre; Gavin, Daniel; Gee, Ian; Ghosh, Deb; Goldsmith, Christopher; Gorard, David; Gordon, John N.; Gore, Steve; Green, John; Grimes, David; Hamill, Grace; Harbord, Marcus; Hart, James; Hawkey, Chris; Iqbal, Tariq; Ireland, Alan; Johnson, Matt; Jones, Colin; Kanegasundaram, Suren; Karban, Amir; Katsanos, Konstantinos H.; Kiparissi, Fevronia; Kirkham, Sian; Lal, Simon; Langlands, Sarah; Lawrance, Ian C.; Lees, Charlie W.; Lev-Tzion, Raffi; Levison, Scott; Lewis, Stephen J.; Li, Andy; Limdi, Jimmy; Lin, Simeng; Lobo, Alan; Lockett, Melanie; Loehry, Juliette; MacDonald, Chris; MacFaul, George; Mahmood, Tariq; Mann, Steve; Mawdsley, Joel; Mazhar, Zia; McGovern, Jane F.; McNair, Alistair; Modi, Anita; Monahan, Kevin; Moran, Alex; Morris, Mary-Anne; Mortimore, Marianne; Mowat, Craig; Muhammed, Rafeeq; Murray, Charles D. R.; Olivier, Hanlie; Orchard, Timothy R.; Panter, Simon; Patel, Vinod; Phillips, Rosemary; Prasad, Neeraj; Preston, Cathryn; Radford-Smith, Graham; Rajasekhar, Praveen; Roy, Dipak; Saich, Rebecca; Satsangi, Jack; Schreiber, Stefan; Sen, Sandip; Shah, Neil; Shenderay, Richard; Shenoy, Acuth; Shutt, James; Silverberg, Mark; Simmons, Alison; Simmons, Jonathan; Singh, Salil; Smith, Malcolm; Smith, Mark; Smith, Melissa; Snook, Jonathon A.; Sonwalker, Sunil; Stevens, Christine R.; Sturniolo, Giacomo; Subramanian, Sreedhar; Thomas, Amanda; Tighe, Mark; Torrente, Franco; Tremelling, Mark; Tsianos, Epameinondas; Vani, Deven; Walsh, Alissa; Watermeyer, Gillian; Watts, David; Watts, Gill; Weaver, Sean; Wesley, Emma; Willmott, Anne; Yearsley, Karen; Zambar, Veena; Zeissig, Sebastian 分享 收藏
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
