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M

Marcos Lorca

universidad viña del mar
H指数:5
被引数:121

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Structure-Guided Discovery of Benzoic-Acid-Based TRPC6 Ligands: An Integrated Docking, MD, and MM-GBSA SAR Study: Potential Therapeutic Molecules for Autism Spectrum Disorder

结构导向的苯甲酸基TRPC6配体发现：综合对接、分子动力学和MM-GBSA构效关系研究：自闭症谱系障碍的潜在治疗分子

Pharmaceuticals
IF4.8
2026-03-030
OAAI
Nicolás Ignacio Silva; Gianfranco Sabadini; David Cabezas; Cristofer González; Paulina González; Jiao Luo; Cristian O. Salas; Marco Mellado; Marcos Lorca; Javier Romero-Parra; Jaime Mella
Design of Hybrid Quinoline–Chalcone Compounds Against Leishmania amazonensis Based on Computational Techniques: 2D- and 3D-QSAR with Experimental Validation

基于计算技术的针对利什曼原虫（Leishmania amazonensis）的杂合喹啉-查尔酮化合物设计：2D-和3D-QSAR与实验验证

Pharmaceuticals 2025, Vol. 18, Page 1567
IF0
2025-10-170
OAAI
Marcos Lorca; Gisela C. Muscia; Jaime Mella; Luciana Thomaz; Jenicer K. Yokoyama-Yasunaka; Daniel Moraga; Yeray A. Rodriguez-Nuñez; Silvia E. Asís; Mauro Cortez; Marco Mellado
Benzo[d]imidazole–Naphthalen-Arylmethanone Regioisomers as CB1 Ligands: Evaluation of Agonism via an Indirect Cytotoxicity-Based Approach

苯并[d]咪唑-萘基芳基甲酮同分异构体作为CB1配体：通过间接细胞毒性为基础的方法评估激动剂活性

International Journal of Molecular Sciences 2025, Vol. 26, Page 9986
IF0
2025-10-140
OAAI
Analia Young Hwa Cho; Renato Burgos Ravanal; Valeria Zuñiga Salazar; Marco Mellado; Marcos Lorca; David Pessoa-Mahana; Jaime Mella; Germán Günther Sapunar; Javier Romero-Parra
Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2020-07-0119
PREAI
Rodriguez-Lavado, Julio; Gallardo-Garrido, Carlos; Mallea, Michael; Bustos, Victor; Osorio, Rodrigo; Hodar-Salazar, Martin; Chung, Hery; Araya-Maturana, Ramiro; Lorca, Marcos; David Pessoa-Mahana, C.; Mella-Raipan, Jaime; Saitz, Claudio; Jaque, Pablo; Reyes-Parada, Miguel; Iturriaga-Vasquez, Patricio; Pessoa-Mahana, Hernan

研究方向

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J
Jaime Mella
H 指数:18论文数:76被引数:816
M
Marco Mellado
H 指数:16论文数:70被引数:756
J
Javier Romero‐Parra
H 指数:10论文数:39被引数:353
C
C. David Pessoa‐Mahana
H 指数:17论文数:70被引数:849
M
Miguel Reyes‐Parada
H 指数:22论文数:82被引数:1,467
P
Patricio Iturriaga‐Vásquez
H 指数:19论文数:71被引数:1,188
C
Cesar Morales‐Verdejo
H 指数:16论文数:91被引数:832
S
Silvia E. Ası́s
H 指数:12论文数:40被引数:442
G
Gisela C. Muscia
H 指数:10论文数:28被引数:380
H
Hery Chung
H 指数:10论文数:12被引数:219