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R

Richard B. Lock

UNSW
H指数:66
被引数:1.4万

个人简介

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工作经历

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荣誉奖项

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P-glycoprotein as a chemotherapy resistance mechanism and biomarker of poor response in high-risk neuroblastoma
EJC Paediatric Oncology
IF0
2025-11-010
OA
Atkinson, Caroline; Kamili, Alvin; Tactacan, Carole M.; Jayatilleke, Nisitha; Rosser, Sebastian P. A.; Saletta, Federica; Gana, Christine C.; Graber, Philipp; Wanninayaka, Amanda; Ignacio, Rosa Mistica C.; Kavallaris, Maria; Gifford, Andrew J.; Lock, Richard B.; Norris, Murray D.; Haber, Michelle; Mayoh, Chelsea; Nath, Christa E.; Trahair, Toby N.; Fletcher, Jamie I.
Polyamine depletion limits progression of acute leukaemia
INTERNATIONAL JOURNAL OF CANCER
IF4.7
2025-02-220
PRE
Gao, Weiman; Karsa, Mawar; Xiao, Lin; Spurling, Dayna; Karsa, Ayu; Ronca, Emma; Bongers, Angelika; Guo, Xinyi; Mayoh, Chelsea; Azfar, Mujahid; Verhelst, Steven H. L.; Tanaka, Katsunori; Cheung, Laurence C.; Kotecha, Rishi S.; Lock, Richard B.; Burns, Mark R.; Vangheluwe, Peter; Norris, Murray D.; Haber, Michelle; Somers, Klaartje
Lessons learned from 20 years of preclinical testing in pediatric cancers

从20年的儿科癌症临床前测试中吸取的经验教训

PHARMACOLOGY & THERAPEUTICS
IF12.5
2024-12-010
PRE
Smith, Malcolm A.; Houghton, Peter J.; Lock, Richard B.; Maris, John M.; Gorlick, Richard; Kurmasheva, Raushan T.; Li, Xiao-Nan; Teicher, Beverly A.; Chuang, Jeffrey H.; Cruz, Filemon S. Dela; Dyer, Michael A.; Kung, Andrew L.; Lloyd, Michael W.; Mosse, Yael P.; Stearns, Timothy M.; Stewart, Elizabeth A.; Bult, Carol J.; Erickson, Stephen W.
PU.1 eviction at lymphocyte-specific chromatin domains mediates glucocorticoid response in acute lymphoblastic leukemia
NATURE COMMUNICATIONS
IF15.7
2024-11-080
OAAI
Beck, Dominik; Cao, Honghui; Tian, Feng; Huang, Yizhou; Jiang, Miao; Zhao, Han; Tai, Xiaolu; Xu, Wenqian; Kosasih, Hansen J.; Kealy, David J.; Zhao, Weiye; Taylor, Samuel J.; Couttas, Timothy A.; Song, Gaoxian; Chacon-Fajardo, Diego; Walia, Yashna; Wang, Meng; Dowle, Adam A.; Holding, Andrew N.; Bridge, Katherine S.; Zhang, Chao; Wang, Jin; Mi, Jian-Qing; Lock, Richard B.; de Bock, Charles E.; Jing, Duohui
The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia
BLOOD CANCER JOURNAL
IF11.6
2024-11-060
OAAI
Toscan, Cara E.; McCalmont, Hannah; Ashoorzadeh, Amir; Lin, Xiaojing; Fu, Zhe; Doculara, Louise; Kosasih, Hansen J.; Cadiz, Roxanne; Zhou, Anthony; Williams, Sarah; Evans, Kathryn; Khalili, Faezeh; Cai, Ruilin; Yeats, Kristy L.; Gifford, Andrew J.; Pickford, Russell; Mayoh, Chelsea; Xie, Jinhan; Henderson, Michelle J.; Trahair, Toby N.; Patterson, Adam V.; Smaill, Jeff B.; de Bock, Charles E.; Lock, Richard B.
TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells
NATURE COMMUNICATIONS
IF15.7
2024-08-280
OAAI
Truong, Peter; Shen, Sylvie; Joshi, Swapna; Islam, Md Imtiazul; Zhong, Ling; Raftery, Mark J.; Afrasiabi, Ali; Alinejad-Rokny, Hamid; Nguyen, Mary; Zou, Xiaoheng; Bhuyan, Golam Sarower; Sarowar, Chowdhury H.; Ghodousi, Elaheh S.; Stonehouse, Olivia; Mohamed, Sara; Toscan, Cara E.; Connerty, Patrick; Kakadia, Purvi M.; Bohlander, Stefan K.; Michie, Katharine A.; Larsson, Jonas; Lock, Richard B.; Walkley, Carl R.; Thoms, Julie A. I.; Jolly, Christopher J.; Pimanda, John E.
PRECISION GUIDED THERAPY PROVIDES CLINICAL BENEFIT IN H3K27-ALTERED DIFFUSE MIDLINE GLIOMA
NEURO-ONCOLOGY
IF13.4
2024-06-180
OAAI
McKay, Campbell; Power, Phoebe; Staunton, Jordan; Sriharan, Shampavi; Jessop, Sophie; Zhukova, Nataliya; Trinder, Sarah; Govender, Dinisha; Barahona, Paulette; Gifford, Andrew J.; Mignone, Cristina; Xie, Angela; Tax, Gabor; Tsoli, Maria; Dolman, Emmy; Mayoh, Chelsea; Wong, Marie; Cowley, Mark; Marshall, Glenn; Trahair, Toby; Lock, Richard B.; Ekert, Paul; Haber, Michelle; Tyrell, Vanessa; Lau, Loretta; Manoharan, Neevika; Ziegler, David S.; Khuong-Quang, Dong-Anh
Precision-guided treatment in high-risk pediatric cancers
NATURE MEDICINE
IF50
2024-06-067
OAAI
Lau, Loretta M. S.; Khuong-Quang, Dong-Anh; Mayoh, Chelsea; Wong, Marie; Barahona, Paulette; Ajuyah, Pamela; Senapati, Akanksha; Nagabushan, Sumanth; Sherstyuk, Alexandra; Altekoester, Ann-Kristin; Fuentes-Bolanos, Noemi A.; Yeung, Veronica; Sullivan, Ashleigh; Omer, Natacha; Diamond, Yonatan; Jessop, Sophie; Battaglia, Lauren; Zhukova, Nataliya; Cui, Louise; Lin, Angela; Gifford, Andrew J.; Fleuren, Emmy D. G.; Dalla-Pozza, Luciano; Moore, Andrew S.; Khaw, Seong-Lin; Eisenstat, David D.; Gottardo, Nicholas G.; Wood, Paul J.; Tapp, Heather; Alvaro, Frank; McCowage, Geoffrey; Nicholls, Wayne; Hansford, Jordan R.; Manoharan, Neevika; Kotecha, Rishi S.; Mateos, Marion K.; Lock, Richard B.; Tyrrell, Vanessa; Haber, Michelle; Trahair, Toby N.; Cowley, Mark J.; Ekert, Paul G.; Marshall, Glenn M.; Ziegler, David S.
High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer

原发性肿瘤细胞的高通量药物筛选确定治疗高危癌症儿童的治疗策略

CANCER RESEARCH
IF16.6
2023-07-3114
OAAI
Mayoh, Chelsea; Mao, Jie; Xie, Jinhan; Tax, Gabor; Chow, Shu-Oi; Cadiz, Roxanne; Pazaky, Karina; Barahona, Paulette; Ajuyah, Pamela; Trebilcock, Peter; Malquori, Angela; Gunther, Kate; Avila, Anica; Yun, Doo Young; Alfred, Stephanie; Gopalakrishnan, Anjana; Kamili, Alvin; Wong, Marie; Cowley, Mark J.; Jessop, Sophie; Lau, Loretta M. S.; Trahair, Toby N.; Ziegler, David S.; Fletcher, Jamie I.; Gifford, Andrew J.; Tsoli, Maria; Marshall, Glenn M.; Haber, Michelle; Tyrrell, Vanessa; Failes, Timothy W.; Arndt, Greg M.; Lock, Richard B.; Ekert, Paul G.; Dolman, M. Emmy M.
Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2023-05-179
PRE
Moles, Ernest; Howard, Christopher B.; Huda, Pie; Karsa, Mawar; McCalmont, Hannah; Kimpton, Kathleen; Duly, Alastair; Chen, Yongjuan; Huang, Yizhou; Tursky, Melinda L.; Ma, David; Bustamante, Sonia; Pickford, Russell; Connerty, Patrick; Omari, Sofia; Jolly, Christopher J.; Joshi, Swapna; Shen, Sylvie; Pimanda, John E.; Dolnikov, Alla; Cheung, Laurence C.; Kotecha, Rishi S.; Norris, Murray D.; Haber, Michelle; de Bock, Charles E.; Somers, Klaartje; Lock, Richard B.; Thurecht, Kristofer J.; Kavallaris, Maria

研究方向

暂未获取到该数据
M
Malcolm A. Smith
H 指数:81论文数:856被引数:3.4万
K
Kathryn Evans
H 指数:26论文数:91被引数:3,014
M
Michelle Haber
H 指数:65论文数:666被引数:1.6万
C
Chelsea Mayoh
H 指数:33论文数:324被引数:3,968
H
Hernán Carol
H 指数:38论文数:211被引数:4,435
G
Glenn M. Marshall
H 指数:62论文数:528被引数:1.1万
P
Peter J. Houghton
H 指数:104论文数:928被引数:4.0万
M
Murray D. Norris
H 指数:61论文数:515被引数:1.3万
R
Raushan T. Kurmasheva
H 指数:31论文数:402被引数:3,580
R
Richard Görlick
H 指数:89论文数:764被引数:2.9万