Cheung, Belamy B.; Mittra, Ritu; Murray, Jayne; Wang, Qian; Seneviratne, Janith A.; Raipuria, Mukesh; Wong, Iris Poh Ling; Restuccia, David; Gifford, Andrew; Salib, Alice; Sutton, Selina; Huang, Libby; Ferdowsi, Parisa Vahidi; Tsang, Joanna; Sekyere, Eric; Mayoh, Chelsea; Luo, Lin; Brown, Darren L.; Stow, Jennifer L.; Zhu, Shizhen; Young, Richard J.; Solomon, Benjamin J.; Chappaz, Stephane; Kile, Benjamin; Kueh, Andrew; Herold, Marco J.; Hilton, Douglas J.; Liu, Tao; Norris, Murray D.; Haber, Michelle; Carter, Daniel R.; Parker, Michael W.; Marshall, Glenn M.

Runx1t1 is an epigenetic regulator essential for MYCN-driven neuroblastoma tumorigenesis

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-010

PRE

The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis

转录共阻遏物Runx1t1对于MYCN驱动的神经母细胞瘤肿瘤发生至关重要

NATURE COMMUNICATIONS

IF15.7

2024-07-111

OAAI

Murray, Jayne E.; Valli, Emanuele; Milazzo, Giorgio; Mayoh, Chelsea; Gifford, Andrew J.; Fletcher, Jamie I.; Xue, Chengyuan; Jayatilleke, Nisitha; Salehzadeh, Firoozeh; Gamble, Laura D.; Rouaen, Jourdin R. C.; Carter, Daniel R.; Forgham, Helen; Sekyere, Eric O.; Keating, Joanna; Eden, Georgina; Allan, Sophie; Alfred, Stephanie; Kusuma, Frances K.; Clark, Ashleigh; Webber, Hannah; Russell, Amanda J.; de Weck, Antoine; Kile, Benjamin T.; Santulli, Martina; De Rosa, Piergiuseppe; Fleuren, Emmy D. G.; Gao, Weiman; Wilkinson-White, Lorna; Low, Jason K. K.; Mackay, Joel P.; Marshall, Glenn M.; Hilton, Douglas J.; Giorgi, Federico M.; Koster, Jan; Perini, Giovanni; Haber, Michelle; Norris, Murray D.

Spatial profiling of tumor associated cells expressing endoplasmic reticulum stress proteins predicts poor outcomes in pancreatic cancer patients

CANCER RESEARCH

IF16.6

2024-01-160

PRE

Phase 1 study of high-dose DFMO, celecoxib, cyclophosphamide and topotecan for patients with relapsed neuroblastoma: a New Approaches to Neuroblastoma Therapy trial

BRITISH JOURNAL OF CANCER

IF6.8

2024-01-105

Addition of AMXT1501 (polyamine uptake inhibitor) plus DFMO (polyamine synthesis inhibitor) to standard-of-care chemotherapy/anti-GD2 antibody in the TH-MYCN mouse neuroblastoma model, enhances efficacy compared to addition of DFMO alone

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-010

PRE

Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-05-179

PRE

Moles, Ernest; Howard, Christopher B.; Huda, Pie; Karsa, Mawar; McCalmont, Hannah; Kimpton, Kathleen; Duly, Alastair; Chen, Yongjuan; Huang, Yizhou; Tursky, Melinda L.; Ma, David; Bustamante, Sonia; Pickford, Russell; Connerty, Patrick; Omari, Sofia; Jolly, Christopher J.; Joshi, Swapna; Shen, Sylvie; Pimanda, John E.; Dolnikov, Alla; Cheung, Laurence C.; Kotecha, Rishi S.; Norris, Murray D.; Haber, Michelle; de Bock, Charles E.; Somers, Klaartje; Lock, Richard B.; Thurecht, Kristofer J.; Kavallaris, Maria

Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma

SCIENCE ADVANCES

IF12.5

2023-03-038

OAAI

Hastings, Jordan F.; Latham, Sharissa L.; Kamili, Alvin; Wheatley, Madeleine S.; Han, Jeremy Z. R.; Wong-Erasmus, Marie; Phimmachanh, Monica; Nobis, Max; Pantarelli, Chiara; Cadell, Antonia L.; O'Donnell, Yolande E. I.; Leong, King Ho; Lynn, Sophie; Geng, Fan-Suo; Cui, Lujing; Yan, Sabrina; Achinger-Kawecka, Joanna; Stirzaker, Clare; Norris, Murray D.; Haber, Michelle; Trahair, Toby N.; Speleman, Frank; De Preter, Katleen; Cowley, Mark J.; Bogdanovic, Ozren; Timpson, Paul; Cox, Thomas R.; Kolch, Walter; Fletcher, Jamie I.; Fey, Dirk; Croucher, David R.

Inflammatory response to retrotransposons drives tumor drug resistance that can be prevented by reverse transcriptase inhibitors

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-11-308

OAAI

Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2022-11-1710