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I

Irina Kulikovskaya

University of Pennsylvania
H指数:32
被引数:1.0万

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Clinical Trial Results Provide the Rationale to Protect Dual HIV-specific T Cells with a Signaling-Defective HIV Fusion Inhibitor

临床 trial 结果提供了保护 dual HIV-specific T cells 的 rationale，其方法是使用一种 signaling-defective HIV fusion inhibitor。

Molecular Therapy
IF12
2026-01-100
PRE
Pablo Tebas; Julie K. Jadlowsky; Yuqi Zhou; M.Betina Pampena; George J. Leslie; Nan Liu; Sriram Srivatsa; Colby R. Maldini; Jingxin Wang; Chungdhak Jaming Tsang; Ola Mohamed; Josephine Romano; Beth Haggarty; Gabriela Plesa; Avery L. Gaymon; Andrea L. Brennan; Elizabeth Veloso; Bruce L. Levine; Mary E. Putt; Irina Kulikovskaya
Reinfusion of CD19 CAR T cells for relapse prevention and treatment in children with acute lymphoblastic leukemia

CD19 CAR T细胞回输预防和治疗儿童急性淋巴细胞白血病复发

BLOOD ADVANCES
IF7.1
2024-04-291
OAAI
Myers, Regina M.; Devine, Kaitlin; Li, Yimei; Lawrence, Sophie; Leahy, Allison Barz; Liu, Hongyan; Vernau, Lauren; Callahan, Colleen; Baniewicz, Diane; Kadauke, Stephan; McGuire, Regina; Wertheim, Gerald B.; Kulikovskaya, Irina; Gonzalez, Vanessa E.; Fraietta, Joseph A.; DiNofia, Amanda M.; Hunger, Stephen P.; Rheingold, Susan R.; Aplenc, Richard; June, Carl H.; Grupp, Stephan A.; Wray, Lisa; Maude, Shannon L.
T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapy

商业CAR T细胞治疗后T细胞淋巴瘤和继发性原发性恶性肿瘤风险

NATURE MEDICINE
IF50
2024-01-2481
PRE
Ghilardi, Guido; Fraietta, Joseph A.; Gerson, James N.; Van Deerlin, Vivianna M.; Morrissette, Jennifer J. D.; Caponetti, Gabriel C.; Paruzzo, Luca; Harris, Jaryse C.; Chong, Elise A.; Adaniya, Sandra P. Susanibar; Svoboda, Jakub; Nasta, Sunita D.; Ugwuanyi, Ositadimma H.; Landsburg, Daniel J.; Fardella, Eugenio; Waxman, Adam J.; Chong, Emeline R.; Patel, Vrutti; Pajarillo, Raymone; Kulikovskaya, Irina; Lieberman, David B.; Cohen, Adam D.; Levine, Bruce L.; Stadtmauer, Edward A.; Frey, Noelle V.; Vogl, Dan T.; Hexner, Elizabeth O.; Barta, Stefan K.; Porter, David L.; Garfall, Alfred L.; Schuster, Stephen J.; June, Carl H.; Ruella, Marco
Anti-BCMA/CD19 CAR T Cells with Early Immunomodulatory Maintenance for Multiple Myeloma Responding to Initial or Later-Line Therapy

抗BCMA/CD19 CAR T细胞与多发性骨髓瘤的早期免疫调节维持对初始或后续治疗有反应

BLOOD CANCER DISCOVERY
IF11.5
2022-11-2144
OAAI
Garfall, Alfred L.; Cohen, Adam D.; Susanibar-Adaniya, Sandra P.; Hwang, Wei-Ting; Vogl, Dan T.; Waxman, Adam J.; Lacey, Simon F.; Gonzalez, Vanessa E.; Fraietta, Joseph A.; Gupta, Minnal; Kulikovskaya, Irina; Tian, Lifeng; Chen, Fang; Koterba, Natalka; Bartoszek, Robert L.; Patchin, Margaret; Xu, Rong; Plesa, Gabriela; Siegel, Don L.; Brennan, Andrea; Nelson, Anne Marie; Ferthio, Regina; Cosey, Angela; Shea, Kim-Marie; Leskowitz, Rachel; Four, Megan; Wilson, Wesley, V; Miao, Fei; Lancaster, Eric; Carreno, Beatriz M.; Linette, Gerald P.; Hexner, Elizabeth O.; Young, Regina M.; Bu, Dexiu; Mansfield, Keith G.; Brogdon, Jennifer L.; June, Carl H.; Milone, Michael C.; Stadtmauer, Edward A.
PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial

靶向PSMA的tgf β 不敏感的装甲CAR T细胞在转移性去势抵抗性前列腺癌中的作用: 1期试验

NATURE MEDICINE
IF50
2022-03-21266
OA
Narayan, Vivek; Barber-Rotenberg, Julie S.; Jung, In-Young; Lacey, Simon F.; Rech, Andrew J.; Davis, Megan M.; Hwang, Wei-Ting; Lal, Priti; Carpenter, Erica L.; Maude, Shannon L.; Plesa, Gabriela; Vapiwala, Neha; Chew, Anne; Moniak, Michael; Sebro, Ronnie A.; Farwell, Michael D.; Marshall, Amy; Gilmore, Joan; Lledo, Lester; Dengel, Karen; Church, Sarah E.; Hether, Tyler D.; Xu, Jun; Gohil, Mercy; Buckingham, Thomas H.; Yee, Stephanie S.; Gonzalez, Vanessa E.; Kulikovskaya, Irina; Chen, Fang; Tian, Lifeng; Tien, Kyle; Gladney, Whitney; Nobles, Christopher L.; Raymond, Hayley E.; Hexner, Elizabeth O.; Siegel, Donald L.; Bushman, Frederic D.; June, Carl H.; Fraietta, Joseph A.; Haas, Naomi B.
BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-08-1658
OA
Kong, Weimin; Dimitri, Alexander; Wang, Wenliang; Jung, In-Young; Ott, Christopher J.; Fasolino, Maria; Wang, Yan; Kulikovskaya, Irina; Gupta, Minnal; Yoder, Todd; DeNizio, Jamie E.; Everett, John K.; Williams, Erik F.; Xu, Jun; Scholler, John; Reich, Tyler J.; Bhoj, Vijay G.; Haines, Kathleen M.; Maus, Marcela, V; Melenhorst, J. Joseph; Young, Regina M.; Jadlowsky, Julie K.; Marcucci, Katherine T.; Bradner, James E.; Levine, Bruce L.; Porter, David L.; Bushman, Frederic D.; Kohli, Rahul M.; June, Carl H.; Davis, Megan M.; Lacey, Simon F.; Vahedi, Golnaz; Fraietta, Joseph A.
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia (vol 24, pg 563, 2018)
NATURE MEDICINE
IF50
2021-02-0510
OAAI
Fraietta, Joseph A.; Lacey, Simon F.; Orlando, Elena J.; Pruteanu-Malinici, Iulian; Gohil, Mercy; Lundh, Stefan; Boesteanu, Alina C.; Wang, Yan; O'Connor, Roddy S.; Hwang, Wei-Ting; Pequignot, Edward; Ambrose, David E.; Zhang, Changfeng; Wilcox, Nicholas; Bedoya, Felipe; Dorfmeier, Corin; Chen, Fang; Tian, Lifeng; Parakandi, Harit; Gupta, Minnal; Young, Regina M.; Johnson, F. Brad; Kulikovskaya, Irina; Liu, Li; Xu, Jun; Kassim, Sadik H.; Davis, Megan M.; Levine, Bruce L.; Frey, Noelle V.; Siegel, Donald L.; Huang, Alexander C.; Wherry, E. John; Bitter, Hans; Brogdon, Jennifer L.; Porter, David L.; June, Carl H.; Melenhorst, J. Joseph
CRISPR-engineered T cells in patients with refractory cancer

难治性癌症患者的CRISPR工程T细胞

Science
IF45.8
2020-01-010
OAAI
Edward Allen Stadtmauer; Joseph A. Fraietta; Megan M. Suhoski; Adam D. Cohen; KRISTY L. WEBER; Eric Lancaster; Patricia A Mangan; Irina M. Kulikovskaya; Minnal Gupta; Fang Chen; Lifeng Tian; Vanessa E. Gonzalez; Jun Xu; In-Young Jung; Jan Joseph Melenhorst; Gabriela Plesa; Joanne Shea; Tina Matlawski; Amanda Cervini; Avery L. Gaymon; Stephanie Desjardins; Anne Lamontagne; January Salas-McKee; Andrew D. Fesnak; Don L. Siegel; Bruce L. Levine; Julie K. Jadlowsky; Regina M. Young; Anne Chew; Wei‐Ting Hwang; Elizabeth Olson Hexner; Beatriz M. Carreno; Christopher L. Nobles; Frederic D. Bushman; Kevin R. Parker; Yanyan Qi; Ansuman T. Satpathy; Howard Y. Chang; Yangbing Zhao; Simon Francis Lacey; Carl H. June
Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma (vol 3, e120505, 2018)
JCI INSIGHT
IF6.1
2019-02-2143
OA
Garfall, Alfred L.; Stadtmauer, Edward A.; Hwang, Wei-Ting; Lacey, Simon F.; Melenhorst, Jan Joseph; Krevvata, Maria; Carroll, Martin P.; Matsui, William H.; Wang, Qiuju; Dhodapkar, Madhav V.; Dhodapkar, Kavita; Das, Rituparna; Vogl, Dan T.; Weiss, Brendan M.; Cohen, Adam D.; Mangan, Patricia A.; Ayers, Emily C.; Nunez-Cruz, Selene; Kulikovskaya, Irina; Davis, Megan M.; Lamontagne, Anne; Dengel, Karen; Kerr, Naseem D. S.; Young, Regina M.; Siegel, Donald L.; Levine, Bruce L.; Milone, Michael C.; Maus, Marcela V.; June, Carl H.
Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

通过转导单个白血病b细胞诱导对嵌合抗原受体T细胞疗法的抗性

NATURE MEDICINE
IF50
2018-10-01511
OAAI
Ruella, Marco; Xu, Jun; Barrett, David M.; Fraietta, Joseph A.; Reich, Tyler J.; Ambrose, David E.; Klichinsky, Michael; Shestova, Olga; Patel, Prachi R.; Kulikovskaya, Irina; Nazimuddin, Farzana; Bhoj, Vijay G.; Orlando, Elena J.; Fry, Terry J.; Bitter, Hans; Maude, Shannon L.; Levine, Bruce L.; Nobles, Christopher L.; Bushman, Frederic D.; Young, Regina M.; Scholler, John; Gill, Saar I.; June, Carl H.; Grupp, Stephan A.; Lacey, Simon F.; Melenhorst, J. Joseph
Activity of Mesothelin-Specific Chimeric Antigen Receptor T Cells Against Pancreatic Carcinoma Metastases in a Phase 1 Trial

在1期试验中，间皮素特异性嵌合抗原受体T细胞对胰腺癌转移的活性

GASTROENTEROLOGY
IF25.1
2018-07-01382
OAAI
Beatty, Gregory L.; O'Hara, Mark H.; Lacey, Simon F.; Torigian, Drew A.; Nazimuddin, Farzana; Chen, Fang; Kulikovskaya, Irina M.; Soulen, Michael C.; McGarvey, Maureen; Nelson, Anne Marie; Gladney, Whitney L.; Levine, Bruce L.; Melenhorst, J. Joseph; Plesa, Gabriela; June, Carl H.
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

慢性淋巴细胞白血病对CD19嵌合抗原受体 (CAR) T细胞治疗的反应和抵抗的决定因素

NATURE MEDICINE
IF50
2018-04-301.3K
OAAI
Fraietta, Joseph A.; Lacey, Simon F.; Orlando, Elena J.; Pruteanu-Malinici, Iulian; Gohil, Mercy; Lundh, Stefan; Boesteanu, Alina C.; Wang, Yan; O'Connor, Roddy S.; Hwang, Wei-Ting; Pequignot, Edward; Ambrose, David E.; Zhang, Changfeng; Wilcox, Nicholas; Bedoya, Felipe; Dorfmeier, Corin; Chen, Fang; Tian, Lifeng; Parakandi, Harit; Gupta, Minnal; Young, Regina M.; Johnson, F. Brad; Kulikovskaya, Irina; Liu, Li; Xu, Jun; Kassim, Sadik H.; Davis, Megan M.; Levine, Bruce L.; Frey, Noelle V.; Siegel, Donald L.; Huang, Alexander C.; Wherry, E. John; Bitter, Hans; Brogdon, Jennifer L.; Porter, David L.; June, Carl H.; Melenhorst, J. Joseph
Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma
JCI INSIGHT
IF6.1
2018-04-19133
OAAI
Garfall, Alfred L.; Stadtmauer, Edward A.; Hwang, Wei-Ting; Lacey, Simon F.; Melenhorst, Jan Joseph; Krevvata, Maria; Carroll, Martin P.; Matsui, William H.; Wang, Qiuju; Dhodapkar, Madhav V.; Dhodapkar, Kavita; Das, Rituparna; Vogl, Dan T.; Weiss, Brendan M.; Cohen, Adam D.; Mangan, Patricia A.; Ayers, Emily C.; Nunez-Cruz, Selene; Kulikovskaya, Irina; Davis, Megan M.; Lamontagne, Anne; Dengel, Karen; Kerr, Naseem D. S.; Young, Regina M.; Siegel, Donald L.; Levine, Bruce L.; Milone, Michael C.; Maus, Marcela V.; June, Carl H.

研究方向

暂未获取到该数据
C
Carl H. June
H 指数:177论文数:1,428被引数:14.4万
S
Simon F. Lacey
H 指数:75论文数:382被引数:3.8万
B
Bruce L. Levine
H 指数:102论文数:550被引数:6.6万
M
Minnal Gupta
H 指数:19论文数:39被引数:7,509
J
Joseph A. Fraietta
H 指数:45论文数:359被引数:1.5万
J
J. Joseph Melenhorst
H 指数:60论文数:293被引数:2.9万
W
Wei‐Ting Hwang
H 指数:72论文数:533被引数:2.6万
E
Edward A. Stadtmauer
H 指数:88论文数:628被引数:3.6万
R
Regina M. Young
H 指数:39论文数:139被引数:1.3万
G
Gabriela Plesa
H 指数:40论文数:245被引数:1.3万