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B

Burgess B. Freeman

st jude childrens research hospital
H指数:25
被引数:2,470

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Targeting the p53 pathway to treat atypical teratoid rhabdoid tumors

靶向p53通路治疗非典型性横纹肌样瘤

Adaptation-The Journal of Literature on Screen Studies
IF0.4
2026-01-010
PRE
Refaat, Alaa; Cho, Hyekyung P.; Williams, Justin S.; Stripay, Jennifer; Blankenship, Kaley; Mercer, Kimberly S.; De Vries, Rebekah; Connelly, Michele; Ganguly, Debolina; Robinson, Sarah; Savage, Evan; Twarog, Nathaniel R.; Attery, Ayush; Laha, Dipranjan; Yu, Kaiwen; Poudel, Suresh; Dhanda, Sandeep K.; Stewart, Clinton F.; Freeman, Burgess B.; Roberts, Charles W. M.; Tinkle, Christopher; Stewart, Elizabeth A.; Upadhyaya, Santhosh A.; Shelat, Anang A.; Roussel, Martine F.
Nuclear Transport as a Therapeutic Vulnerability in ZFTA-RELA Ependymoma

ZFTA-RELA室管膜瘤中核转运作为治疗性易损靶点

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Ippagunta, Siri; Arabzade, Amir; Varadharajan, Srinidhi; Emanus, Erik; Bland, Amanda; Kardian, Alisha; Laboe, Nicolas; Sun, Hua; Zheng, Tuyu; Orisme, Wilda; Johnson, Melissa; Rodgers, Britanny; Turner, Gregory; Steinberg, Jeffrey; Freeman, Burgess; Roussel, Martine; Shelat, Anang; Kriwacki, Richard; Merchant, Thomas; Deneen, Benjamin; Miller, Shondra; Kavirayani, Anoop Murthy; Ellison, David; Onar-thomas, Arzu; Robinson, Giles; Mack, Stephen; Bertrand, Kelsey
RBM39 degrader invigorates innate immunity to eradicate neuroblastoma despite cancer cell plasticity

RBM39降解剂通过激活固有免疫来清除神经母细胞瘤，尽管存在癌细胞可塑性。

Nature Communications
IF15.7
2025-09-170
OAAI
Shivendra Singh; Jie Fang; Hongjian Jin; Lee-Ann Van De Velde; Andrew Cortes; Jiani Chen; Sivaraman Natarajan; Evon Poon; Qiong Wu; Christopher L. Morton; Mary A. Woolard; Waise Quarni; Jacob A. Steele; Jon P. Connelly; Liusheng He; Rebecca Thorne; Gregory Turner; Thomas Confer; Melissa Johnson; William V. Caufield; Burgess B. Freeman; Timothy Lockey; Andrew J. Murphy; Peter J. Murray; Takashi Owa; Shondra M. Pruett-Miller; Ruoning Wang; Louis Chesler; Julie R. Park; Andrew M. Davidoff; John Easton; Xiang Chen; Paul G. Thomas; Jun Yang; Burgess B. Freeman III
Venetoclax plus gilteritinib is effective in preclinical models of FLT3-mutant BCL11B-a lineage ambiguous leukemia

维奈克拉联合吉特利替尼在FLT3突变BCL11B-a谱系模糊性白血病的体外模型中是有效的。

Blood
IF23.1
2025-08-180
OA
Lindsey E. Montefiori; Ilaria Iacobucci; Qingsong Gao; Jamila Moore; William C. Wright; Huimei Wei; Pradyumna Baviskar; Surbhi Sona; Hongjian Jin; Amit Budhraja; Josi Lott; Qi Zhang Tatarata; Zhongshan Cheng; Tanya Khan; Emily A. Backhaus Wagner; Melissa Johnson; Cyrus M. Mehr; Burgess Freeman; Laura Janke; Torsten Haferlach; Paul Geeleher; Paul E. Mead; Marina Konopleva; Joseph T. Opferman; Charles G. Mullighan
Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk

儿童 γ δ t-all的生物学和临床分析将LMO2/STAG2重排确定为极高风险

CANCER DISCOVERY
IF33.3
2024-06-242
PRE
Kimura, Shunsuke; Park, Chun Shik; Montefiori, Lindsey E.; Iacobucci, Ilaria; Poeloenen, Petri; Gao, Qingsong; Arnold, Elizabeth D.; Attarbaschi, Andishe; Brown, Anthony; Buldini, Barbara; Caldwell, Kenneth J.; Chang, Yunchao; Chen, Chelsey; Cheng, Cheng; Cheng, Zhongshan; Choi, John; Conter, Valentino; Crews, Kristine R.; de Groot-Kruseman, Hester A.; Deguchi, Takao; Eguchi, Mariko; Muhle, Hannah E.; Elitzur, Sarah; Escherich, Gabriele; Freeman, Burgess B.; Gu, Zhaohui; Han, Katie; Horibe, Keizo; Imamura, Toshihiko; Jeha, Sima; Kato, Motohiro; Chiew, Kean H.; Khan, Tanya; Kicinski, Michal; Koehrer, Stefan; Kornblau, Steven M.; Kotecha, Rishi S.; Li, Chi-Kong; Liu, Yen-Chun; Locatelli, Franco; Luger, Selina M.; Paietta, Elisabeth M.; Manabe, Atsushi; Marquart, Hanne V.; Masetti, Riccardo; Maybury, Mellissa; Mazilier, Pauline; Meijerink, Jules P. P.; Mitchell, Sharnise; Miyamura, Takako; Moore, Andrew S.; Oshima, Koichi; Pawinska-Wasikowska, Katarzyna; Pieters, Rob; Prater, Mollie S.; Pruett-Miller, Shondra M.; Pui, Ching-Hon; Qu, Chunxu; Reiterova, Michaela; Reyes, Noemi; Roberts, Kathryn G.; Rowe, Jacob M.; Sato, Atsushi; Schmiegelow, Kjeld; Schrappe, Martin; Shen, Shuhong; Skoczen, Szymon; Spinelli, Orietta; Stary, Jan; Svaton, Michael; Takagi, Masatoshi; Takita, Junko; Tang, Yanjing; Teachey, David T.; Thomas, Paul G.; Tomizawa, Daisuke; Trka, Jan; Varotto, Elena; Vincent, Tiffaney L.; Yang, Jun J.; Yeoh, Allen E. J.; Zhou, Yinmei; Zimmermann, Martin; Inaba, Hiroto; Mullighan, Charles G.
Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy

卡马替尼是MET融合驱动的小儿高级别胶质瘤的有效治疗方法，并与放疗协同作用

MOLECULAR CANCER
IF33.9
2024-06-072
OAAI
Zuckermann, Marc; He, Chen; Andrews, Jared; Bagchi, Aditi; Sloan-Henry, Roketa; Bianski, Brandon; Xie, Jia; Wang, Yingzhe; Twarog, Nathaniel; Onar-Thomas, Arzu; Ernst, Kati J.; Yang, Lei; Li, Yong; Zhu, Xiaoyan; Ocasio, Jennifer K.; Budd, Kaitlin M.; Dalton, James; Li, Xiaoyu; Chepyala, Divyabharathi; Zhang, Junyuan; Xu, Ke; Hover, Laura; Roach, Jordan T.; Chan, Kenneth Chun-Ho; Hofmann, Nina; Mckinnon, Peter J.; Pfister, Stefan M.; Shelat, Anang A.; Rankovic, Zoran; Freeman, Burgess B.; Chiang, Jason; Jones, David T. W.; Tinkle, Christopher L.; Baker, Suzanne J.
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition
NATURE COMMUNICATIONS
IF15.7
2024-04-251
OAAI
Shendy, Noha A. M.; Bikowitz, Melissa; Sigua, Logan H.; Zhang, Yang; Mercier, Audrey; Khashana, Yousef; Nance, Stephanie; Liu, Qi; Delahunty, Ian M.; Robinson, Sarah; Goel, Vanshita; Rees, Matthew G.; Ronan, Melissa A.; Wang, Tingjian; Kocak, Mustafa; Roth, Jennifer A.; Wang, Yingzhe; Freeman, Burgess B.; Orr, Brent A.; Abraham, Brian J.; Roussel, Martine F.; Schonbrunn, Ernst; Qi, Jun; Durbin, Adam D.
Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy (vol 24, pg 427, 2018)
NATURE MEDICINE
IF50
2024-01-080
OA
Badders, Nisha M.; Korff, Ane; Miranda, Helen C.; Vuppala, Pradeep K.; Smith, Rebecca B.; Winborn, Brett J.; Quemin, Emmanuelle R.; Sopher, Bryce L.; Dearman, Jennifer; Messing, James; Kim, Nam Chul; Moore, Jennifer; Freibaum, Brian D.; Kanagaraj, Anderson P.; Fan, Baochang; Tillman, Heather; Chen, Ping-Chung; Wang, Yingzhe; Freeman III, Burgess B.; Li, Yimei; Kim, Hong Joo; La Spada, Albert R.; Taylor, J. Paul
ATM inhibition enhances the efficacy of radiation across distinct molecular subgroups of pediatric high-grade glioma

ATM抑制增强了小儿高级别神经胶质瘤不同分子亚群的辐射功效

NEURO-ONCOLOGY
IF13.4
2023-03-275
OA
Xie, Jia; Kuriakose, Teneema; Bianski, Brandon; Twarog, Nathaniel; Savage, Evan; Xu, Ke; Zhu, Xiaoyan; He, Chen; Hansen, Baranda; Wang, Hong; High, Anthony; Li, Yuxin; Rehg, Jerold E.; Tillman, Heather S.; Freeman, Burgess B.; Rankovic, Zoran; Onar-Thomas, Arzu; Fan, Yiping; Wu, Gang; Peng, Junmin; Miller, Shondra; Baker, Suzanne J.; Shelat, Anang A.; Tinkle, Christopher L.
The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma
NATURE COMMUNICATIONS
IF15.7
2021-11-0944
OAAI
Pan, Min; Wright, William C.; Chapple, Richard H.; Zubair, Asif; Sandhu, Manbir; Batchelder, Jake E.; Huddle, Brandt C.; Low, Jonathan; Blankenship, Kaley B.; Wang, Yingzhe; Gordon, Brittney; Archer, Payton; Brady, Samuel W.; Natarajan, Sivaraman; Posgai, Matthew J.; Schuetz, John; Miller, Darcie; Kalathur, Ravi; Chen, Siquan; Connelly, Jon Patrick; Babu, M. Madan; Dyer, Michael A.; Pruett-Miller, Shondra M.; Freeman, Burgess B., III; Chen, Taosheng; Godley, Lucy A.; Blanchard, Scott C.; Stewart, Elizabeth; Easton, John; Geeleher, Paul
Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma
NATURE COMMUNICATIONS
IF15.7
2021-07-0238
OAAI
He, Chen; Xu, Ke; Zhu, Xiaoyan; Dunphy, Paige S.; Gudenas, Brian; Lin, Wenwei; Twarog, Nathaniel; Hover, Laura D.; Kwon, Chang-Hyuk; Kasper, Lawryn H.; Zhang, Junyuan; Li, Xiaoyu; Dalton, James; Jonchere, Barbara; Mercer, Kimberly S.; Currier, Duane G.; Caufield, William; Wang, Yingzhe; Xie, Jia; Broniscer, Alberto; Wetmore, Cynthia; Upadhyaya, Santhosh A.; Qaddoumi, Ibrahim; Klimo, Paul; Boop, Frederick; Gajjar, Amar; Zhang, Jinghui; Orr, Brent A.; Robinson, Giles W.; Monje, Michelle; Freeman, Burgess B., III; Roussel, Martine F.; Northcott, Paul A.; Chen, Taosheng; Rankovic, Zoran; Wu, Gang; Chiang, Jason; Tinkle, Christopher L.; Shelat, Anang A.; Baker, Suzanne J.
Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
2021-05-3110
OAAI
Diouf, Barthelemy; Wing, Claudia; Panetta, John C.; Eddins, Donnie; Lin, Wenwei; Yang, Wenjian; Fan, Yiping; Pei, Deqing; Cheng, Cheng; Delaney, Shannon M.; Zhang, Wei; Bonten, Erik J.; Crews, Kristine R.; Paugh, Steven W.; Li, Lie; Freeman, Burgess B., III; Autry, Robert J.; Beard, Jordan A.; Ferguson, Daniel C.; Janke, Laura J.; Ness, Kirsten K.; Chen, Taosheng; Zakharenko, Stanislav S.; Jeha, Sima; Pui, Ching-Hon; Relling, Mary V.; Eileen Dolan, M.; Evans, William E.
Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase 1a/b trial
LANCET INFECTIOUS DISEASES
IF31
2020-08-0145
OAAI
Gaur, Aditya H.; McCarthy, James S.; Panetta, John C.; Dallas, Ronald H.; Woodford, John; Tang, Li; Smith, Amber M.; Stewart, Tracy B.; Branum, Kristen C.; Freeman, Burgess B., III; Patel, Nehali D.; John, Elizabeth; Chalon, Stephan; Ost, Shelley; Heine, Ryan N.; Richardson, Julie L.; Christensen, Robbin; Flynn, Patricia M.; Van Gessel, Yvonne; Mitasev, Branko; Moehrle, Joerg J.; Gusovsky, Fabian; Bebrevska, Lidiya; Guy, R. Kiplin

研究方向

暂未获取到该数据
A
Anang A. Shelat
H 指数:42论文数:250被引数:6,742
Y
Yingzhe Wang
H 指数:34论文数:228被引数:3,309
M
Martine F. Roussel
H 指数:96论文数:653被引数:3.7万
T
Taosheng Chen
H 指数:50论文数:297被引数:7,809
C
Clinton F. Stewart
H 指数:76论文数:534被引数:1.9万
E
Elizabeth Stewart
H 指数:25论文数:80被引数:2,481
W
William Caufield
H 指数:8论文数:20被引数:602
N
Nathaniel Twarog
H 指数:13论文数:106被引数:848
Z
Zoran Ranković
H 指数:30论文数:219被引数:6,175
J
John Easton
H 指数:72论文数:464被引数:2.7万