Mayra Shanley

The University of Texas MD Anderson Cancer Center

H指数:16

被引数:1,891

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Genome-wide CRISPR screens identify critical targets to enhance CAR-NK cell antitumor potency

全基因组CRISPR筛选鉴定出增强CAR-NK细胞抗肿瘤效力的关键靶点

Cancer Cell

IF44.5

2025-08-210

OAAI

Alexander Biederstädt; Rafet Basar; Jeong-Min Park; Nadima Uprety; Rejeena Shrestha; Francia Reyes Silva; Merve Dede; John Watts; Sunil Acharya; Donghai Xiong; Bin Liu; May Daher; Hind Rafei; Pinaki Banerjee; Ping Li; Sanjida Islam; Huihui Fan; Mayra Shanley; Jingling Jin; Bijender Kumar; Vernikka Woods; Paul Lin; Silvia Tiberti; Ana Karen Nunez Cortes; Xin Ru Jiang; Inci Biederstädt; Patrick Zhang; Ye Li; Seema Rawal; Enli Liu; Luis Muniz-Feliciano; Gary M. Deyter; Elizabeth J. Shpall; Natalie Wall Fowlkes; Ken Chen; Katayoun Rezvani

Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells

通过CD38 CAR工程化NK细胞克服急性髓系白血病中CD226相关的免疫逃逸

CELL REPORTS

IF6.9

2025-01-010

BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-09-110

PRE

Kumar, Bijender; Singh, Anand; Basar, Rafet; Uprety, Nadima; Li, Ye; Fan, Huihui; Cortes, Ana Karen Nunez; Kaplan, Mecit; Acharya, Sunil; Shaim, Hila; Xu, Anna C.; Wu, Manrong; Ensley, Emily; Fang, Dexing; Banerjee, Pinaki P.; Garcia, Luciana Melo; Tiberti, Silvia; Lin, Paul; Rafei, Hind; Munir, Maliha Nuzhat; Moore, Madison; Shanley, Mayra; Mendt, Mayela; Kerbauy, Lucila N.; Liu, Bin; Biederstaedt, Alexander; Gokdemir, Elif; Ghosh, Susmita; Kundu, Kiran; Reyes-Silva, Francia; Jiang, Xin Ru; Wan, Xinhai; Gilbert, April L.; Dede, Merve; Mohanty, Vakul; Dou, Jinzhuang; Zhang, Patrick; Liu, Enli; Muniz-Feliciano, Luis; Deyter, Gary M.; Jain, Abhinav K.; Rodriguez-Sevilla, Juan Jose; Colla, Simona; Garcia-Manero, Guillermo; Shpall, Elizabeth J.; Chen, Ken; Abbas, Hussein A.; Rai, Kunal; Rezvani, Katayoun; Daher, May

CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis

CANCER DISCOVERY

IF33.3

2024-07-223

PRE

Acharya, Sunil; Basar, Rafet; Daher, May; Rafei, Hind; Li, Ping; Uprety, Nadima; Ensley, Emily; Shanley, Mayra; Kumar, Bijender; Banerjee, Pinaki P.; Melo Garcia, Luciana; Lin, Paul; Mohanty, Vakul; Kim, Kun H.; Jiang, Xianli; Pan, Yuchen; Li, Ye; Liu, Bin; Cortes, Ana K. Nunez; Zhang, Chenyu; Fathi, Mohsen; Rezvan, Ali; Montalvo, Melisa J.; Cha, Sophia L.; Reyes-Silva, Francia; Shrestha, Rejeena; Guo, Xingliang; Kundu, Kiran; Biederstadt, Alexander; Muniz-Feliciano, Luis; Deyter, Gary M.; Kaplan, Mecit; Jiang, Xin R.; Liu, Enli; Jain, Antrix; Roszik, Janos; Fowlkes, Natalie W.; Solis Soto, Luisa M.; Raso, Maria G.; Khoury, Joseph D.; Lin, Pei; Vega, Francisco; Varadarajan, Navin; Chen, Ken; Marin, David; Shpall, Elizabeth J.; Rezvani, Katayoun

KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape (vol 28, pg 2133, 2022)

NATURE MEDICINE

IF50

2024-01-050

Li, Ye; Basar, Rafet; Wang, Guohui; Liu, Enli; Moyes, Judy S.; Li, Li; Kerbauy, Lucila N.; Uprety, Nadima; Fathi, Mohsen; Rezvan, Ali; Banerjee, Pinaki P.; Muniz-Feliciano, Luis; Laskowski, Tamara J.; Ensley, Emily; Daher, May; Shanley, Mayra; Mendt, Mayela; Acharya, Sunil; Liu, Bin; Biederstaedt, Alexander; Rafei, Hind; Guo, Xingliang; Melo Garcia, Luciana; Lin, Paul; Ang, Sonny; Marin, David; Chen, Ken; Bover, Laura; Champlin, Richard E.; Varadarajan, Navin; Shpall, Elizabeth J.; Rezvani, Katayoun

Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering

SCIENCE ADVANCES

IF12.5

2023-07-2838

OAAI

Activated B cells suppress T-cell function through metabolic competition

活化的b细胞通过代谢竞争抑制T细胞功能

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2022-12-218

OAAI

KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape

NATURE MEDICINE

IF50

2022-09-2983

Li, Ye; Basar, Rafet; Wang, Guohui; Liu, Enli; Moyes, Judy S.; Li, Li; Kerbauy, Lucila N.; Uprety, Nadima; Fathi, Mohsen; Rezvan, Ali; Banerjee, Pinaki P.; Muniz-Feliciano, Luis; Laskowski, Tamara J.; Ensley, Emily; Daher, May; Shanley, Mayra; Mendt, Mayela; Acharya, Sunil; Liu, Bin; Biederstadt, Alexander; Rafei, Hind; Guo, Xingliang; Melo Garcia, Luciana; Lin, Paul; Ang, Sonny; Marin, David; Chen, Ken; Bover, Laura; Champlin, Richard E.; Varadarajan, Navin; Shpall, Elizabeth J.; Rezvani, Katayoun

Engineered cord blood megakaryocytes evade killing by allogeneic T-cells for refractory thrombocytopenia

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-09-201

OAAI

Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells

靶向 α v整合素/tgf-β 轴可改善自然杀伤细胞对胶质母细胞瘤干细胞的功能

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2021-07-15140

Shaim, Hila; Shanley, Mayra; Basar, Rafet; Daher, May; Gumin, Joy; Zamler, Daniel B.; Uprety, Nadima; Wang, Fang; Huang, Yuefan; Gabrusiewicz, Konrad; Miao, Qi; Dou, Jinzhuang; Alsuliman, Abdullah; Kerbauy, Lucila N.; Acharya, Sunil; Mohanty, Vakul; Mendt, Mayela; Li, Sufang; Lu, JunJun; Wei, Jun; Fowlkes, Natalie W.; Gokdemir, Elif; Ensley, Emily L.; Kaplan, Mecit; Kassab, Cynthia; Li, Li; Ozcan, Gonca; Banerjee, Pinaki P.; Shen, Yifei; Gilbert, April L.; Jones, Corry M.; Bdiwi, Mustafa; Nunez-Cortes, Ana K.; Liu, Enli; Yu, Jun; Imahashi, Nobuhiko; Muniz-Feliciano, Luis; Li, Ye; Hu, Jian; Draetta, Giulio; Marin, David; Yu, Dihua; Mielke, Stephan; Eyrich, Matthias; Champlin, Richard E.; Chen, Ken; Lang, Frederick F.; Shpall, Elizabeth J.; Heimberger, Amy B.; Rezvani, Katayoun

Generation of glucocorticoid-resistant SARS-CoV-2 T cells for adoptive cell therapy

CELL REPORTS

IF6.9

2021-07-0125

OAAI

Basar, Rafet; Uprety, Nadima; Ensley, Emily; Daher, May; Klein, Kimberly; Martinez, Fernando; Aung, Fleur; Shanley, Mayra; Hu, Bingqian; Gokdemir, Elif; Mendt, Mayela; Silva, Francia Reyes; Acharya, Sunil; Laskowski, Tamara; Muniz-Feliciano, Luis; Banerjee, Pinaki; Li, Ye; Li, Sufang; Garcia, Luciana Melo; Lin, Paul; Shaim, Hila; Yates, Sean G.; Marin, David; Kaur, Indreshpal; Rao, Sheetal; Mak, Duncan; Lin, Angelique; Miao, Qi; Dou, Jinzhuang; Chen, Ken; Champlin, Richard; Shpall, Elizabeth J.; Rezvani, Katayoun

Metabolic Reprogramming of GMP Grade Cord Tissue Derived Mesenchymal Stem Cells Enhances Their Suppressive Potential in GVHD

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-05-0416

OAAI

Mendt, Mayela; Daher, May; Basar, Rafet; Shanley, Mayra; Kumar, Bijender; Wei Inng, Francesca Lim; Acharya, Sunil; Shaim, Hila; Fowlkes, Natalie; Tran, Jamie P.; Gokdemir, Elif; Uprety, Nadima; Nunez-Cortes, Ana K.; Ensley, Emily; Mai, Thao; Kerbauy, Lucila N.; Melo-Garcia, Luciana; Lin, Paul; Shen, Yifei; Mohanty, Vakul; Lu, JunJun; Li, Sufang; Nandivada, Vandana; Wang, Jing; Banerjee, Pinaki; Reyes-Silva, Francia; Liu, Enli; Ang, Sonny; Gilbert, April; Li, Ye; Wan, Xinhai; Gu, Jun; Zhao, Ming; Baran, Natalia; Muniz-Feliciano, Luis; Wilson, Jeffrey; Kaur, Indreshpal; Gagea, Mihai; Konopleva, Marina; Marin, David; Tang, Guilin; Chen, Ken; Champlin, Richard; Rezvani, Katayoun; Shpall, Elizabeth J.

GMP-Compliant Universal Antigen Presenting Cells (uAPC) Promote the Metabolic Fitness and Antitumor Activity of Armored Cord Blood CAR-NK Cells

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-02-2635

OAAI

Mayra Shanley

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