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Sunil Acharya

The University of Texas MD Anderson Cancer Center
H指数:18
被引数:1,466

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Genome-wide CRISPR screens identify critical targets to enhance CAR-NK cell antitumor potency

全基因组CRISPR筛选鉴定出增强CAR-NK细胞抗肿瘤效力的关键靶点

Cancer Cell
IF44.5
2025-08-210
OAAI
Alexander Biederstädt; Rafet Basar; Jeong-Min Park; Nadima Uprety; Rejeena Shrestha; Francia Reyes Silva; Merve Dede; John Watts; Sunil Acharya; Donghai Xiong; Bin Liu; May Daher; Hind Rafei; Pinaki Banerjee; Ping Li; Sanjida Islam; Huihui Fan; Mayra Shanley; Jingling Jin; Bijender Kumar; Vernikka Woods; Paul Lin; Silvia Tiberti; Ana Karen Nunez Cortes; Xin Ru Jiang; Inci Biederstädt; Patrick Zhang; Ye Li; Seema Rawal; Enli Liu; Luis Muniz-Feliciano; Gary M. Deyter; Elizabeth J. Shpall; Natalie Wall Fowlkes; Ken Chen; Katayoun Rezvani
Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells

通过CD38 CAR工程化NK细胞克服急性髓系白血病中CD226相关的免疫逃逸

CELL REPORTS
IF6.9
2025-01-010
OA
Garcia, Luciana Melo; Gangadharan, Achintyan; Banerjee, Pinaki; Li, Ye; Zeng, Andy G. X.; Rafei, Hind; Lin, Paul; Kumar, Bijender; Acharya, Sunil; Daher, May; Muniz-Feliciano, Luis; Deyter, Gary M.; Dominguez, Gabriel; Park, Jeong Min; Silva, Francia Reyes; Cortes, Ana Karen Nunez; Basar, Rafet; Uprety, Nadima; Shanley, Mayra
Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition

星形胶质细胞诱导的Cdk5通过抑制mhc-i表达逃避免疫识别促进乳腺癌脑转移

NATURE CELL BIOLOGY
IF19.1
2024-09-201
PRE
Yuzhalin, Arseniy E.; Lowery, Frank J.; Saito, Yohei; Yuan, Xiangliang; Yao, Jun; Duan, Yimin; Ding, Jingzhen; Acharya, Sunil; Zhang, Chenyu; Fajardo, Abigail; Chen, Hao-Nien; Wei, Yongkun; Sun, Yutong; Zhang, Lin; Xiao, Yi; Li, Ping; Lorenzi, Philip L.; Huse, Jason T.; Fan, Huihui; Zhao, Zhongming; Hung, Mien-Chie; Yu, Dihua
BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2024-09-110
PRE
Kumar, Bijender; Singh, Anand; Basar, Rafet; Uprety, Nadima; Li, Ye; Fan, Huihui; Cortes, Ana Karen Nunez; Kaplan, Mecit; Acharya, Sunil; Shaim, Hila; Xu, Anna C.; Wu, Manrong; Ensley, Emily; Fang, Dexing; Banerjee, Pinaki P.; Garcia, Luciana Melo; Tiberti, Silvia; Lin, Paul; Rafei, Hind; Munir, Maliha Nuzhat; Moore, Madison; Shanley, Mayra; Mendt, Mayela; Kerbauy, Lucila N.; Liu, Bin; Biederstaedt, Alexander; Gokdemir, Elif; Ghosh, Susmita; Kundu, Kiran; Reyes-Silva, Francia; Jiang, Xin Ru; Wan, Xinhai; Gilbert, April L.; Dede, Merve; Mohanty, Vakul; Dou, Jinzhuang; Zhang, Patrick; Liu, Enli; Muniz-Feliciano, Luis; Deyter, Gary M.; Jain, Abhinav K.; Rodriguez-Sevilla, Juan Jose; Colla, Simona; Garcia-Manero, Guillermo; Shpall, Elizabeth J.; Chen, Ken; Abbas, Hussein A.; Rai, Kunal; Rezvani, Katayoun; Daher, May
CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis
CANCER DISCOVERY
IF33.3
2024-07-223
PRE
Acharya, Sunil; Basar, Rafet; Daher, May; Rafei, Hind; Li, Ping; Uprety, Nadima; Ensley, Emily; Shanley, Mayra; Kumar, Bijender; Banerjee, Pinaki P.; Melo Garcia, Luciana; Lin, Paul; Mohanty, Vakul; Kim, Kun H.; Jiang, Xianli; Pan, Yuchen; Li, Ye; Liu, Bin; Cortes, Ana K. Nunez; Zhang, Chenyu; Fathi, Mohsen; Rezvan, Ali; Montalvo, Melisa J.; Cha, Sophia L.; Reyes-Silva, Francia; Shrestha, Rejeena; Guo, Xingliang; Kundu, Kiran; Biederstadt, Alexander; Muniz-Feliciano, Luis; Deyter, Gary M.; Kaplan, Mecit; Jiang, Xin R.; Liu, Enli; Jain, Antrix; Roszik, Janos; Fowlkes, Natalie W.; Solis Soto, Luisa M.; Raso, Maria G.; Khoury, Joseph D.; Lin, Pei; Vega, Francisco; Varadarajan, Navin; Chen, Ken; Marin, David; Shpall, Elizabeth J.; Rezvani, Katayoun
KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape (vol 28, pg 2133, 2022)
NATURE MEDICINE
IF50
2024-01-050
OA
Li, Ye; Basar, Rafet; Wang, Guohui; Liu, Enli; Moyes, Judy S.; Li, Li; Kerbauy, Lucila N.; Uprety, Nadima; Fathi, Mohsen; Rezvan, Ali; Banerjee, Pinaki P.; Muniz-Feliciano, Luis; Laskowski, Tamara J.; Ensley, Emily; Daher, May; Shanley, Mayra; Mendt, Mayela; Acharya, Sunil; Liu, Bin; Biederstaedt, Alexander; Rafei, Hind; Guo, Xingliang; Melo Garcia, Luciana; Lin, Paul; Ang, Sonny; Marin, David; Chen, Ken; Bover, Laura; Champlin, Richard E.; Varadarajan, Navin; Shpall, Elizabeth J.; Rezvani, Katayoun
Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering
SCIENCE ADVANCES
IF12.5
2023-07-2838
OAAI
Li, Li; Mohanty, Vakul; Dou, Jinzhuang; Huang, Yuefan; Banerjee, Pinaki P.; Miao, Qi; Lohr, Jens G.; Vijaykumar, Tushara; Frede, Julia; Knoechel, Birgit; Muniz-Feliciano, Luis; Laskowski, Tamara J.; Liang, Shaoheng; Moyes, Judy S.; Nandivada, Vandana; Basar, Rafet; Kaplan, Mecit; Daher, May; Liu, Enli; Li, Ye; Acharya, Sunil; Lin, Paul; Shanley, Mayra; Rafei, Hind; Marin, David; Mielke, Stephan; Champlin, Richard E.; Shpall, Elizabeth J.; Chen, Ken; Rezvani, Katayoun
KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape
NATURE MEDICINE
IF50
2022-09-2983
OA
Li, Ye; Basar, Rafet; Wang, Guohui; Liu, Enli; Moyes, Judy S.; Li, Li; Kerbauy, Lucila N.; Uprety, Nadima; Fathi, Mohsen; Rezvan, Ali; Banerjee, Pinaki P.; Muniz-Feliciano, Luis; Laskowski, Tamara J.; Ensley, Emily; Daher, May; Shanley, Mayra; Mendt, Mayela; Acharya, Sunil; Liu, Bin; Biederstadt, Alexander; Rafei, Hind; Guo, Xingliang; Melo Garcia, Luciana; Lin, Paul; Ang, Sonny; Marin, David; Chen, Ken; Bover, Laura; Champlin, Richard E.; Varadarajan, Navin; Shpall, Elizabeth J.; Rezvani, Katayoun
Engineered cord blood megakaryocytes evade killing by allogeneic T-cells for refractory thrombocytopenia
FRONTIERS IN IMMUNOLOGY
IF5.9
2022-09-201
OAAI
Kumar, Bijender; Afshar-Kharghan, Vahid; Mendt, Mayela; Sackstein, Robert; Tanner, Mark R. R.; Popat, Uday; Ramdial, Jeremy; Daher, May; Jimenez, Juan; Basar, Rafet; Garcia, Luciana Melo; Shanley, Mayra; Kaplan, Mecit; Wan, Xinhai; Nandivada, Vandana; Silva, Francia Reyes; Woods, Vernikka; Gilbert, April; Gonzalez-Delgado, Ricardo; Acharya, Sunil; Lin, Paul; Rafei, Hind; Banerjee, Pinaki Prosad; Shpall, Elizabeth J.
Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells

靶向 α v整合素/tgf-β 轴可改善自然杀伤细胞对胶质母细胞瘤干细胞的功能

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-07-15140
OA
Shaim, Hila; Shanley, Mayra; Basar, Rafet; Daher, May; Gumin, Joy; Zamler, Daniel B.; Uprety, Nadima; Wang, Fang; Huang, Yuefan; Gabrusiewicz, Konrad; Miao, Qi; Dou, Jinzhuang; Alsuliman, Abdullah; Kerbauy, Lucila N.; Acharya, Sunil; Mohanty, Vakul; Mendt, Mayela; Li, Sufang; Lu, JunJun; Wei, Jun; Fowlkes, Natalie W.; Gokdemir, Elif; Ensley, Emily L.; Kaplan, Mecit; Kassab, Cynthia; Li, Li; Ozcan, Gonca; Banerjee, Pinaki P.; Shen, Yifei; Gilbert, April L.; Jones, Corry M.; Bdiwi, Mustafa; Nunez-Cortes, Ana K.; Liu, Enli; Yu, Jun; Imahashi, Nobuhiko; Muniz-Feliciano, Luis; Li, Ye; Hu, Jian; Draetta, Giulio; Marin, David; Yu, Dihua; Mielke, Stephan; Eyrich, Matthias; Champlin, Richard E.; Chen, Ken; Lang, Frederick F.; Shpall, Elizabeth J.; Heimberger, Amy B.; Rezvani, Katayoun
Metabolic Reprogramming of GMP Grade Cord Tissue Derived Mesenchymal Stem Cells Enhances Their Suppressive Potential in GVHD
FRONTIERS IN IMMUNOLOGY
IF5.9
2021-05-0416
OAAI
Mendt, Mayela; Daher, May; Basar, Rafet; Shanley, Mayra; Kumar, Bijender; Wei Inng, Francesca Lim; Acharya, Sunil; Shaim, Hila; Fowlkes, Natalie; Tran, Jamie P.; Gokdemir, Elif; Uprety, Nadima; Nunez-Cortes, Ana K.; Ensley, Emily; Mai, Thao; Kerbauy, Lucila N.; Melo-Garcia, Luciana; Lin, Paul; Shen, Yifei; Mohanty, Vakul; Lu, JunJun; Li, Sufang; Nandivada, Vandana; Wang, Jing; Banerjee, Pinaki; Reyes-Silva, Francia; Liu, Enli; Ang, Sonny; Gilbert, April; Li, Ye; Wan, Xinhai; Gu, Jun; Zhao, Ming; Baran, Natalia; Muniz-Feliciano, Luis; Wilson, Jeffrey; Kaur, Indreshpal; Gagea, Mihai; Konopleva, Marina; Marin, David; Tang, Guilin; Chen, Ken; Champlin, Richard; Rezvani, Katayoun; Shpall, Elizabeth J.
GMP-Compliant Universal Antigen Presenting Cells (uAPC) Promote the Metabolic Fitness and Antitumor Activity of Armored Cord Blood CAR-NK Cells
FRONTIERS IN IMMUNOLOGY
IF5.9
2021-02-2635
OAAI
Liu, Enli; Ang, Sonny O. T.; Kerbauy, Lucila; Basar, Rafet; Kaur, Indreshpal; Kaplan, Mecit; Li, Li; Tong, Yijiu; Daher, May; Ensley, Emily L.; Uprety, Nadima; Nunez Cortes, Ana Karen; Yang, Ryan Z.; Li, Ye; Shaim, Hila; Reyes Silva, Francia; Lin, Paul; Mohanty, Vakul; Acharya, Sunil; Shanley, Mayra; Muniz-Feliciano, Luis; Banerjee, Pinaki P.; Chen, Ken; Champlin, Richard E.; Shpall, Elizabeth J.; Rezvani, Katayoun
Large-scale GMP-compliant CRISPR-Cas9-mediated deletion of the glucocorticoid receptor in multivirus-specific T cells
BLOOD ADVANCES
IF7.1
2020-07-2724
OAAI
Basar, Rafet; Daher, May; Uprety, Nadima; Gokdemir, Elif; Alsuliman, Abdullah; Ensley, Emily; Ozcan, Gonca; Mendt, Mayela; Sanabria, Mayra Hernandez; Kerbauy, Lucila Nassif; Cortes, Ana Karen Nunez; Li, Li; Banerjee, Pinaki P.; Muniz-Feliciano, Luis; Acharya, Sunil; Fowlkes, Natalie W.; Lu, Junjun; Li, Sufang; Mielke, Stephan; Kaplan, Mecit; Nandivada, Vandana; Bdaiwi, Mustafa; Kontoyiannis, Alexander D.; Li, Ye; Liu, Enli; Ang, Sonny; Marin, David; Brunetti, Lorenzo; Gundry, Michael C.; Turk, Rolf; Schubert, Mollie S.; Rettig, Garrett R.; McNeill, Matthew S.; Kurgan, Gavin; Behlke, Mark A.; Champlin, Richard; Shpall, Elizabeth J.; Rezvani, Katayoun

研究方向

暂未获取到该数据
R
Rafet Başar
H 指数:30论文数:178被引数:8,384
M
May Daher
H 指数:33论文数:223被引数:6,293
P
Pinaki P. Banerjee
H 指数:41论文数:197被引数:1.0万
M
Mayra Shanley
H 指数:16论文数:84被引数:1,891
L
Luis Muniz-Feliciano
H 指数:19论文数:86被引数:1,653
E
Elizabeth J. Shpall
H 指数:101论文数:1,606被引数:4.7万
N
Nadima Uprety
H 指数:20论文数:99被引数:1,898
Y
Ye Li
H 指数:38论文数:252被引数:6,575
K
Katayoun Rezvani
H 指数:73论文数:542被引数:2.7万
E
Enli Liu
H 指数:33论文数:157被引数:1.2万