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P

Paul G. Ekert

Peter MacCallum Cancer Centre
H指数:55
被引数:1.4万

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荣誉奖项

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Programmable and selective silencing of oncogenic fusion transcripts by CRISPR-Cas13b via breakpoint sequence recognition

通过CRISPR-Cas13b识别断裂点序列对癌基因融合转录本进行可编程和选择性沉默

Science Advances
IF12.5
2026-10-160
OA
Wenxin Hu (胡文欣); Honglin Chen (陈竑霖); Steven He; Joshua M. L. Casan; Carolyn Shembrey; Sharon Li; Lauren M. Brown; Andrea Zhao; Lynda Truong; Isabella Buchner; Dane Vassiliadis; Timothy P. Hughes; Deborah L. White; Catherine L. Carmichael; Antoine De Weck; Ilia Voskoboinik; Quentin Gouil; Joseph A. Trapani; Paul G. Ekert; Teresa Sadras; Mohamed Fareh
Precision-guided therapy in H3K27-altered diffuse midline glioma

H3K27-改变的弥漫性中线胶质瘤中的精准导向疗法

Nature Communications
IF15.7
2026-05-190
OAAI
Campbell J. L. McKay; Chelsea Mayoh; Phoebe Power; Sophie Jessop; Shampavi Sriharan; Jordan Staunton; Sarah Trinder; Nataliya Zhukova; Cristina Mignone; Dinisha Govender; Frank Alvaro; Peter Downie; Jordan R. Hansford; Tim Hassall; Santosh Valvi; Marion K. Mateos; Paulette Barahona; Andrew J. Gifford; Gabor Tax; Maria Tsoli; Emmy M. Dolman; Marie Wong; Mark Cowley; Glenn M. Marshall; Toby N. Trahair; Paul G. Ekert; Michelle Haber; Vanessa Tyrell; Loretta M. S. Lau; Neevika Manoharan; David S. Ziegler; Dong-Anh Khuong-Quang
Novel paediatric case of a spinal high-grade astrocytoma with piloid features in a patient with Noonan Syndrome

Noonan综合征患者中具有piloid特征的脊柱高级星形细胞瘤的新儿科病例

NPJ PRECISION ONCOLOGY
IF8
2024-10-190
OA
Staunton, Jordan; Ajuyah, Pamela; Harris, Angela; Mayoh, Chelsea; Wong, Marie; Rumford, Megan; Sullivan, Patricia J.; Ekert, Paul G.; Fuentes-Bolanos, Noemi; Cowley, Mark J.; Lau, Loretta M. S.; Ziegler, David S.; Barahona, Paulette; Manoharan, Neevika
Clinical utility of real-time comprehensive molecular profiling in childhood brain tumors
CANCER RESEARCH
IF16.6
2024-09-050
PRE
Lau, Loretta M. S.; Khuong-Quang, Dong-Anh; Staunton, Jordan; Sanders, Nicholas; Sriharan, Shampavi; Trinder, Sarah; Manoharan, Neevika; Barahona, Paulette; Altekoester, Ann-Kristin; Dias, Kimberley; Rumford, Megan; Sylvester, Dianne; Parhar, Jasmine; Mateos, Marion K.; Wong, Marie; Mayoh, Chelsea; Cowley, Mark J.; Ekert, Paul G.; Haber, Michelle; Tyrrell, Vanessa; Ziegler, David S.
Transcriptome-based assessment of immune infiltration for molecular selection of pediatric patients with solid tumors for combination immune checkpoint inhibitor therapy
CANCER RESEARCH
IF16.6
2024-09-050
PRE
Shen, Yaoqing; Mayoh, Chelsea; Nabbi, Arash; Santiago, Raoul; Bianco, Stephanie; Bancarz, Iain R.; Williamson, Laura; Corbett, Richard; Krekhno, Zakhar; Davidson, Scott; Fortuna, Alexander; Yuki, Kyoko E.; Connolly, Denise; Morgenstern, Daniel; Ekert, Paul G.; Shlien, Adam; Jones, Steven J. M.; Deyell, Rebecca J.; Cohen-Gogo, Sarah
Implementing ultra-sensitive, ctDNA-based liquid biopsy for disease monitoring in paediatric tumours
CANCER RESEARCH
IF16.6
2024-09-050
PRE
Salomon, Robert; Chen, Wenhan; Shale, Charles; Toumari, Mojgan; Lowe, Aileen; Li, Wenyan; Chen, Jingwei; Bazaz, Sajad Razavi; Barahona, Paulette; Cui, Louise; Mayoh, Chelsea; El-Kamand, Sam; Tryell, Vanessa; Wong-Erasmus, Marie; Lau, Loretta M. S.; Bolanos, Noemi Fuentes; Cuppen, Edwin; Dong Anh Khuong Quang; Staunton, Jordan; Mateos, Marion K.; Trahair, Toby; Haber, Michelle; Ziegler, David S.; Ekert, Paul G.; Priestley, Peter; Cowley, Mark J.
Single-base tiled screen unveils design principles of PspCas13b for potent and off-target-free RNA silencing

单碱基平铺屏幕揭示了PspCas13b的设计原理，用于有效和脱靶无RNA沉默

NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2024-07-012
OAAI
Hu, Wenxin; Kumar, Amit; Ahmed, Syed Faraz; Qi, Shijiao; Ma, David K. G.; Chen, Honglin; Singh, Gurjeet J.; Casan, Joshua M. L.; Haber, Michelle; Voskoboinik, Ilia; McKay, Matthew R.; Trapani, Joseph A.; Ekert, Paul G.; Fareh, Mohamed
PRECISION GUIDED THERAPY PROVIDES CLINICAL BENEFIT IN H3K27-ALTERED DIFFUSE MIDLINE GLIOMA
NEURO-ONCOLOGY
IF13.4
2024-06-180
OAAI
McKay, Campbell; Power, Phoebe; Staunton, Jordan; Sriharan, Shampavi; Jessop, Sophie; Zhukova, Nataliya; Trinder, Sarah; Govender, Dinisha; Barahona, Paulette; Gifford, Andrew J.; Mignone, Cristina; Xie, Angela; Tax, Gabor; Tsoli, Maria; Dolman, Emmy; Mayoh, Chelsea; Wong, Marie; Cowley, Mark; Marshall, Glenn; Trahair, Toby; Lock, Richard B.; Ekert, Paul; Haber, Michelle; Tyrell, Vanessa; Lau, Loretta; Manoharan, Neevika; Ziegler, David S.; Khuong-Quang, Dong-Anh

研究方向

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C
Chelsea Mayoh
H 指数:33论文数:324被引数:3,922
M
Mark J. Cowley
H 指数:63论文数:409被引数:1.9万
M
Michelle Haber
H 指数:65论文数:666被引数:1.6万
D
David S. Ziegler
H 指数:45论文数:632被引数:8,456
L
Loretta M. S. Lau
H 指数:43论文数:201被引数:1.8万
D
David L. Vaux
H 指数:85论文数:272被引数:3.3万
M
Marie Wong
H 指数:18论文数:99被引数:2,968
P
Paulette Barahona
H 指数:10论文数:77被引数:832
L
Lauren M. Brown
H 指数:17论文数:55被引数:1,110
V
Vanessa Tyrrell
H 指数:16论文数:86被引数:1,246