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A

Aaron R. Thorner

center for cancer genomics
H指数:50
被引数:1.2万

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Fusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinoma

融合驱动致癌程序塑造重排型肾细胞癌的免疫景观

Nature Communications
IF15.7
2026-08-260
OA
Prathyusha Konda; Alexandra J. Wakolbinger; Yantong Cui; Gabriel Roberti de Oliveira; Yasmin L. Nabil; Cary N. Weiss; Maxwell D. Seager; Riva Deodhar; Jiao Li; Sayed Matar; Jinyu Wang; Jack Horst; Sabrina Y. Camp; Aseman B. Sheshdeh; Jonathan L. Hecht; David J. Einstein; Yashika Rustagi; Anwesha Nag; Aaron R. Thorner; Cheng-Zhong Zhang; Eliezer M. Van Allen; Sabina Signoretti; Toni K. Choueiri; Srinivas R. Viswanathan
Single-cell epigenetic profiling reveals a tumor-intrinsic interferon response program in ccRCC tied to poor prognosis and BAP1 loss

单细胞表观遗传图谱揭示了一种与不良预后和BAP1缺失相关的ccRCC肿瘤内干扰素应答程序。

Science Advances
IF12.5
2026-02-200
OA
Sabrina Y. Camp; Meng Xiao He; Michael S. Cuoco; Amanda E. Garza; Sherin Xirenayi; Ziad Bakouny; Eddy Saad; Jad El Masri; Erica Pimenta; Kevin Meli; Chris Labaki; Breanna M. Titchen; Yun Jee Kang; Jack Horst; Rachel Trowbridge; Erin Shannon; Karla Helvie; Aaron R. Thorner; Sébastien Vigneau; Angie Mayorga; Jahnavi Kodali; Hannah Lachmayr; Meredith Bemus; Pengsheng Chen; Haiteng Deng; Jihye Park; Toni K. Choueiri; Kevin Bi; Eliezer M. Van Allen
Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity
Science Translational Medicine
IF14.6
2026-01-210
PRE
Erica M. Pimenta; Amanda E. Garza; Sabrina Y. Camp; Jihye Park; Samantha E. Hoffman; Laura Valderrábano; Jingxin Fu; Kevin Bi; Maximilian T. Carson; Julie Karam; Breanna M. Titchen; Sofia Medjahed; Melin J. Khandekar; Erin Shannon; Yun Jee Kang; Shannon Coy; Jia-Ren Lin; Anwesha Nag; Aaron R. Thorner; William J. Gibson; Sandro Santagata; Chandrajit P. Raut; Jason L. Hornick; Priscilla Merriam; Nicole L. Solimini; Suzanne George; George D. Demetri; Eliezer M. Van Allen
Cellular reprogramming during anti-PD-1 and chemotherapy treatment in early-stage primary hormone receptor-positive breast cancer

早期激素受体阳性乳腺癌在抗PD-1和化疗治疗期间细胞的重编程

Nature Communications
IF15.7
2025-11-280
OAAI
Jingxin Fu; Adrienne G. Waks; Erica Pimenta; Breanna Titchen; Kevin Bi; Sabrina Camp; Theodora Pappa; Tanya Keenan; Erin Shannon; Sébastien Vigneau; Meredith Bemus; Anwesha Nag; Aaron R. Thorner; Jihye Park; Molly DiLullo; Eileen Wrabel; Rinath Jeselsohn; Elizabeth A. Mittendorf; Daniel L. Abravanel; Sara M. Tolaney; Eliezer M. Van Allen
Understanding tumor-immune-stromal dynamics driving response and resistance to immune checkpoint blockade in melanoma
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Tarantino, Giuseppe; He, Yiwen; Solanky, Priyanka; Cui, Xinyu; Pfaff, Kathleen; Thorner, Aaron R.; Blosser, Timothy; Boblitt, Elliot; Frangieh, Allison; Aprati, Tyler; Zhang, Boyang; Chen, Jiajia; Faulkner, Hannah Mae; Lawless, Aleigha; Manos, Michael; Helvie, Karla; Sharova, Tatyana; Frederick, Dennie; Krishna, Sachi; Mangum, Chanell; Abbondanza, Domenic; Mccann, Cai; Johnson, Bruce; Shalek, Alex K.; Van Allen, Eliezer; Zhuang, Xiaowei; Sullivan, Ryan; Engelhardt, Barbara; Farhi, Sami; Rodig, Scott; Hodi, F. Stephen; Boland, Genevieve M.; Liu, David
fusion derived oncogenic programs shape the immune landscape in translocation renal cell carcinoma

融合衍生致癌程序塑造易位性肾细胞癌的免疫景观

ONCOLOGIST
IF4.2
2025-10-010
OAAI
Konda, Prathyusha; Weiss, Cary; Cui, Yantong; Wang, Jinyu; Matar, Sayed; Laimon, Yasmin Nabil; Sheshdeh, Aseman; Deodhar, Riva; Camp, Sabrina; Horst, Jack; Hecht, Jonathan; Einstein, David; Nag, Anwesha; Thorner, Aaron; Van Allen, Eliezer; Zhang, Cheng-Zhong; Signoretti, Sabina; Choueri, Toni; Viswanathan, Srinivas
A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features

跨临床病理特征的转移性乳腺癌活检的多模态单细胞和空间表达图

NATURE MEDICINE
IF50
2024-10-301
OAAI
Klughammer, Johanna; Abravanel, Daniel L.; Segerstolpe, Asa; Blosser, Timothy R.; Goltsev, Yury; Cui, Yi; Goodwin, Daniel R.; Sinha, Anubhav; Ashenberg, Orr; Slyper, Michal; Vigneau, Sebastien; Jane-Valbuena, Judit; Alon, Shahar; Caraccio, Chiara; Chen, Judy; Cohen, Ofir; Cullen, Nicole; DelloStritto, Laura K.; Dionne, Danielle; Files, Janet; Frangieh, Allison; Helvie, Karla; Hughes, Melissa E.; Inga, Stephanie; Kanodia, Abhay; Lako, Ana; MacKichan, Colin; Mages, Simon; Moriel, Noa; Murray, Evan; Napolitano, Sara; Nguyen, Kyleen; Nitzan, Mor; Ortiz, Rebecca; Patel, Miraj; Pfaff, Kathleen L.; Porter, Caroline B. M.; Rotem, Asaf; Strauss, Sarah; Strasser, Robert; Thorner, Aaron R.; Turner, Madison; Wakiro, Isaac; Waldman, Julia; Wu, Jingyi; Zanudo, Jorge Gomez Tejeda; Zhang, Diane; Lin, Nancy U.; Tolaney, Sara M.; Winer, Eric P.; Boyden, Edward S.; Chen, Fei; Nolan, Garry P.; Rodig, Scott J.; Zhuang, Xiaowei; Rozenblatt-Rosen, Orit; Johnson, Bruce E.; Regev, Aviv; Wagle, Nikhil
Dissecting tumor- immune interaction in response and resistance to immune checkpoint blockade in metastatic melanoma
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Tarantino, Giuseppe; He, Yiwen; Solanky, Priyanka; Thorner, Aaron; Aprati, Tyler; Sullivan, Ryan; Robitschek, Emily; Blosser, Timothy; Zhuang, Xiaowei; Zhuang, Xiaowei; Boblitt, Elliot; Frangieh, Allison; Holovatska, Marta; Lawless, Aleigha; Manos, Michael; Pfaff, Kathleen; Helvie, Karla; Sharova, Tatyana; Frederick, Dennie; Fahey, James Liam; Villamarin, Diego; Farhi, Sami; Rodig, Scott; Johnson, Bruce; Shalek, Alex K.; Van Allen, Eliezer; Hodi, Stephen; Boland, Genevieve M.; Liu, David
Genomic profiling of a randomized trial of interferon-a vs hydroxyurea in MPN reveals mutation-specific responses
BLOOD ADVANCES
IF7.1
2022-03-3031
OAAI
Knudsen, Trine Alma; Skov, Vibe; Stevenson, Kristen; Werner, Lillian; Duke, William; Laurore, Charles; Gibson, Christopher J.; Nag, Anwesha; Thorner, Aaron R.; Wollison, Bruce; Hansen, Dennis Lund; Ellervik, Christina; El Fassi, Daniel; de Stricker, Karin; Ocias, Lukas Frans; Brabrand, Mette; Bjerrum, Ole Weis; Overgaard, Ulrik Malthe; Frederiksen, Mikael; Kristensen, Thomas Kielsgaard; Kruse, Torben A.; Thomassen, Mads; Mourits-Andersen, Torben; Severinsen, Marianne Tang; Stentoft, Jesper; Starklint, Joern; Neuberg, Donna S.; Kjaer, Lasse; Larsen, Thomas Stauffer; Hasselbalch, Hans Carl; Lindsley, R. Coleman; Mullally, Ann
Spatio-molecular dissection of the breast cancer metastatic microenvironment
CANCER RESEARCH
IF16.6
2022-02-150
PRE
Abravanel, Daniel L.; Klughammer, Johanna; Blosser, Timothy; Goltsev, Yury; Jiang, Sizun; Bai, Yunjao; Murray, Evan; Alon, Shahar; Cui, Yi; Goodwin, Daniel R.; Sinha, Anubhav; Cohen, Ofir; Slyper, Michal; Ashenberg, Orr; Dionne, Danielle; Jane-Valbuena, Judit; Porter, Caroline BM.; Segerstolpe, Asa; Waldman, Julia; Vigneau, Sebastien; Helvie, Karla; Frangieh, Allison; DelloStritto, Laura; Patel, Miraj; We, Jingyi; Pfaff, Kathleen; Cullen, Nicole; Lako, Ana; Turner, Madison; Wakiro, Isaac; Napolitano, Sara; Kanodia, Abhay; Ortiz, Rebecca; MacKichan, Colin; Inga, Stephanie; Chen, Judy; Thorner, Aaron R.; Rotem, Asaf; Rodig, Scott; Chen, Fei; Boyden, Edward S.; Nolan, Garry P.; Zhuang, Xiaowei; Rozenblatt-Rosen, Orit; Johnson, Bruce E.; Regev, Aviv; Wagle, Nikhil
Genetic ancestry and lung cancer somatic mutations in patients of Latin American descent: Etiology and treatment implications
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
IF3.4
2022-01-010
PRE
Carrot-Zhang, Jian; Soca-Chafre, Giovanny; Patterson, Nick; Thorner, Aaron; Nag, Anwesha; Watson, Jacqueline; Genovese, Giulio; Rodriguez, July; Gelbard, Maya; Corrales-Rodriguez, Luis; Mitsuishi, Yoichiro; Ha, Gavin; Campbell, Joshua; Oxnard, Geoffrey; Arrieta, Oscar; Cardona, Andres; Gusev, Alexander; Meyerson, Matthew
RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-11-1519
OA
Bekele, Raie T.; Samant, Amruta S.; Nassar, Amin H.; So, Jonathan; Garcia, Elizabeth P.; Curran, Catherine R.; Hwang, Justin H.; Mayhew, David L.; Nag, Anwesha; Thorner, Aaron R.; Borcsok, Judit; Sztupinszki, Zsofia; Pan, Chong-Xian; Bellmunt, Joaquim; Kwiatkowski, David J.; Sonpavde, Guru P.; Van Allen, Eliezer M.; Mouw, Kent W.

研究方向

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M
Matthew Meyerson
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Matthew D. Ducar
H 指数:33论文数:127被引数:1.0万
A
Anwesha Nag
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P
Paul Van Hummelen
H 指数:60论文数:282被引数:1.6万
L
Laura E. MacConaill
H 指数:61论文数:333被引数:2.6万
B
Bruce M. Wollison
H 指数:12论文数:50被引数:1,576
G
Gad Getz
H 指数:248论文数:1,851被引数:35.1万
D
David J. Kwiatkowski
H 指数:135论文数:989被引数:7.9万
W
William C. Hahn
H 指数:147论文数:1,091被引数:10.1万
E
Eliezer M. Van Allen
H 指数:112论文数:1,455被引数:8.0万