Alejo Nevado‐Holgado - Publications, H-index & Citations

Alejo Nevado‐Holgado

university of oxford

38H指数

202论文数

4.8K被引数

收录论文 57

发表时间

Evaluating large language models for assessment of psychosis risk 评估大型语言模型在精神病风险评估中的应用

npj Digital Medicine

IF15.1

2026-07-23

OAAI

Taiyu Zhu; Alexander Tashevski; Maxime Taquet; Matilda Azis; Tia Jani; Matthew R. Broome; Thomas Kabir; Amedeo Minichino; Graham K. Murray; Matthew M. Nour; Ilina Singh; Paolo Fusar-Poli; Alejo Nevado-Holgado; Philip McGuire; Dominic Oliver

Plasma proteome-wide analysis of dementia risk mechanistically implicates synaptic biomarkers 血浆全蛋白质组分析在机制上涉及痴呆风险相关的突触生物标志物

alzheimer's & dementia

IF0

2026-01-10

OAAI

Keenan A. Walker; Jingsha Chen; Liu Shi; Yunju Yang; Myriam Fornage; Linda Zhou; Pascal Schlosser; Aditya Surapaneni; Morgan E Grams; Michael R. Duggan; Zhongsheng Peng; Gabriela T. Gomez; Adrienne Tin; Ron C. Hoogeveen; Kevin J. Sullivan; Peter Ganz; Joni V Lindbohm; Mika Kivimaki; Alejo J Nevado-Holgado; Noel Buckley; Rebecca F. Gottesman; Thomas H. Mosley Jr.; Eric Boerwinkle; Christie M Ballantyne; Josef Coresh

Interplay between age, APOE Ɛ4 and the metabolome in plasma and brain in Alzheimer’s disease 年龄、APOE Ɛ4与血浆和脑代谢组在阿尔茨海默病中的相互作用

Translational Psychiatry

IF6.2

2025-10-31

OAAI

Najaf Amin; Jun Liu; William Sproviero; Matthias Arnold; Richa Batra; Bruno Bonnechere; Yu-Jie Chiou; Marco Fernandes; Jan Krumsiek; Danielle Newby; Kwangsik Nho; Jun Pyo Kim; Andrew J. Saykin; Liu Shi; Laura M. Winchester; Yang Yang; Alejo J. Nevado-Holgado; Gabi Kastenmüller; Rima Kaddurah-Daouk; Cornelia M. van Duijn

The relationship between anaemia, haemoglobin levels, and cognitive function: Evidence in two population-based cohorts from India and the United States 贫血、血红蛋白水平和认知功能之间的关系：来自印度和美国两个基于人群的队列研究的证据

Neurobiology of Disease

IF5.6

2025-09-17

PREAI

Laura M. Winchester; Danielle Newby; Upamanyu Ghose; Peifeng Hu; Hunter Green; Sandy Chien; Janice M. Ranson; Jessica Faul; David Llewellyn; Jinkook Lee; Sarah Bauermeister; Alejo Nevado-Holgado

Machine learning in Alzheimer’s disease genetics 阿尔茨海默病遗传学中的机器学习

Nature Communications

IF15.7

2025-07-22

OAAI

Matthew Bracher-Smith; Federico Melograna; Brittany Ulm; Céline Bellenguez; Benjamin Grenier-Boley; Diane Duroux; Alejo J. Nevado; Peter Holmans; Betty M. Tijms; Marc Hulsman; Itziar de Rojas; Rafael Campos-Martin; Sven van der Lee; Atahualpa Castillo; Fahri Küçükali; Oliver Peters; Anja Schneider; Martin Dichgans; Dan Rujescu; Norbert Scherbaum; Jürgen Deckert; Steffi Riedel-Heller; Lucrezia Hausner; Laura Molina-Porcel; Emrah Düzel; Timo Grimmer; Jens Wiltfang; Stefanie Heilmann-Heimbach; Susanne Moebus; Thomas Tegos; Nikolaos Scarmeas; Oriol Dols-Icardo; Fermin Moreno; Jordi Pérez-Tur; María J. Bullido; Pau Pastor; Raquel Sánchez-Valle; Victoria Álvarez; Mercè Boada; Pablo García-González; Raquel Puerta; Pablo Mir; Luis M. Real; Gerard Piñol-Ripoll; Jose María García-Alberca; Eloy Rodriguez-Rodriguez; Hilkka Soininen; Sami Heikkinen; Alexandre de Mendonça; Shima Mehrabian; Latchezar Traykov; Jakub Hort; Martin Vyhnalek; Nicolai Sandau; Jesper Qvist Thomassen; Yolande A. L. Pijnenburg; Henne Holstege; John van Swieten; Inez Ramakers; Frans Verhey; Philip Scheltens; Caroline Graff; Goran Papenberg; Vilmantas Giedraitis; Julie Williams; Philippe Amouyel; Anne Boland; Jean-François Deleuze; Gael Nicolas; Carole Dufouil; Florence Pasquier; Olivier Hanon; Stéphanie Debette; Edna Grünblatt; Julius Popp; Roberta Ghidoni; Daniela Galimberti; Beatrice Arosio; Patrizia Mecocci; Vincenzo Solfrizzi; Lucilla Parnetti; Alessio Squassina; Lucio Tremolizzo; Barbara Borroni; Michael Wagner; Benedetta Nacmias; Marco Spallazzi; Davide Seripa; Innocenzo Rainero; Antonio Daniele; Fabrizio Piras; Carlo Masullo; Giacomina Rossi; Frank Jessen; Patrick Kehoe; Tsolaki Magda; Pascual Sánchez-Juan; Kristel Sleegers; Martin Ingelsson; Mikko Hiltunen; Rebecca Sims; Wiesje van der Flier; Ole A. Andreassen; Agustín Ruiz; Alfredo Ramirez; Ruth Frikke-Schmidt; Najaf Amin; Gennady Roshchupkin; Jean-Charles Lambert; Kristel Van Steen; Cornelia van Duijn; Valentina Escott-Price

Changes in iPSC-astrocyte morphology reflect Alzheimer's disease patient clinical markers

Stem Cells

IF3.6

2024-12-20

PREAI

Rowland, Helen A.; Miller, Georgina; Liu, Qiang; Li, Shuhan; Sharp, Nicola R.; Ng, Bryan; Wei, Tina; Arunasalam, Kanisa; Koychev, Ivan; Hedegaard, Anne; Ribe, Elena M.; Chan, Dennis; Chessell, Tharani; Kocagoncu, Ece; Lawson, Jennifer; Malhotra, Paresh; Ridha, Basil H.; Rowe, James B.; Thomas, Alan J.; Zamboni, Giovanna; Zetterberg, Henrik; Cader, M. Zameel; Wade-Martins, Richard; Lovestone, Simon; Nevado-Holgado, Alejo; Kormilitzin, Andrey; Buckley, Noel J.

Developing healthcare language model embedding spaces 开发医疗保健语言模型嵌入空格

ARTIFICIAL INTELLIGENCE IN MEDICINE

IF6.2

2024-12-01

OAAI

Taylor, Niall; Schofield, Dan; Kormilitzin, Andrey; Joyce, Dan W.; Nevado-Holgado, Alejo

Efficiency at scale: Investigating the performance of diminutive language models in clinical tasks 规模效率: 研究临床任务中小型语言模型的性能

ARTIFICIAL INTELLIGENCE IN MEDICINE

IF6.2

2024-11-01

OAAI

Taylor, Niall; Ghose, Upamanyu; Rohanian, Omid; Nouriborji, Mohammadmahdi; Kormilitzin, Andrey; Clifton, David A.; Nevado-Holgado, Alejo

Clinical Prompt Learning With Frozen Language Models

IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS

IF8.9

2024-11-01

OAAI

Taylor, Niall; Zhang, Yi; Joyce, Dan W.; Gao, Ziming; Kormilitzin, Andrey; Nevado-Holgado, Alejo

Model development for bespoke large language models for digital triage assistance in mental health care 用于精神卫生护理中数字分诊辅助的定制大型语言模型的模型开发

ARTIFICIAL INTELLIGENCE IN MEDICINE

IF6.2

2024-11-01

OAAI

Taylor, Niall; Kormilitzin, Andrey; Lorge, Isabelle; Nevado-Holgado, Alejo; Cipriani, Andrea; Joyce, Dan W.

Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF-AD study Emif-ad研究中与阿尔茨海默病CSF生物标志物相关的血液DNA甲基组学特征

ALZHEIMERS & DEMENTIA

IF11.1

2024-08-28

OAAI

Smith, Rebecca G.; Pishva, Ehsan; Kouhsar, Morteza; Imm, Jennifer; Dobricic, Valerija; Johannsen, Peter; Wittig, Michael; Franke, Andre; Vandenberghe, Rik; Schaeverbeke, Jolien; Freund-Levi, Yvonne; Froelich, Lutz; Scheltens, Philip; Teunissen, Charlotte E.; Frisoni, Giovanni; Blin, Olivier; Richardson, Jill C.; Bordet, Regis; Engelborghs, Sebastiaan; de Roeck, Ellen; Martinez-Lage, Pablo; Altuna, Miren; Tainta, Mikel; Lleo, Alberto; Sala, Isabel; Popp, Julius; Peyratout, Gwendoline; Winchester, Laura; Nevado-Holgado, Alejo; Verhey, Frans; Tsolaki, Magda; Andreasson, Ulf; Blennow, Kaj; Zetterberg, Henrik; Streffer, Johannes; Vos, Stephanie J. B.; Lovestone, Simon; Visser, Pieter Jelle; Bertram, Lars; Lunnon, Katie

Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations 蛋白质组老化时钟预测不同人群中常见年龄相关疾病的死亡率和风险

NATURE MEDICINE

IF50

2024-08-08

OAAI

Argentieri, M. Austin; Xiao, Sihao; Bennett, Derrick; Winchester, Laura; Nevado-Holgado, Alejo J.; Ghose, Upamanyu; Albukhari, Ashwag; Yao, Pang; Mazidi, Mohsen; Lv, Jun; Millwood, Iona; Fry, Hannah; Rodosthenous, Rodosthenis S.; Partanen, Jukka; Zheng, Zhili; Kurki, Mitja; Daly, Mark J.; Palotie, Aarno; Adams, Cassandra J.; Li, Liming; Clarke, Robert; Amin, Najaf; Chen, Zhengming; van Duijn, Cornelia M.

The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses

TRANSLATIONAL PSYCHIATRY

IF6.2

2024-05-18

OAAI

Walker, Rosie M.; Chong, Michael; Perrot, Nicolas; Pigeyre, Marie; Gadd, Danni A.; Stolicyn, Aleks; Shi, Liu; Campbell, Archie; Shen, Xueyi; Whalley, Heather C.; Nevado-Holgado, Alejo; McIntosh, Andrew M.; Heitmeier, Stefan; Rangarajan, Sumathy; O'Donnell, Martin; Smith, Eric E.; Yusuf, Salim; Whiteley, William N.; Pare, Guillaume

Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life 中年人血浆蛋白质组学分析鉴定晚年痴呆风险的蛋白质标志物

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-07-19

OAAI

Walker, Keenan A.; Chen, Jingsha; Shi, Liu; Yang, Yunju; Fornage, Myriam; Zhou, Linda; Schlosser, Pascal; Surapaneni, Aditya; Grams, Morgan E.; Duggan, Michael R.; Peng, Zhongsheng; Gomez, Gabriela T.; Tin, Adrienne; Hoogeveen, Ron C.; Sullivan, Kevin J.; Ganz, Peter; Lindbohm, Joni V.; Kivimaki, Mika; Nevado-Holgado, Alejo J.; Buckley, Noel; Gottesman, Rebecca F.; Mosley, Thomas H.; Boerwinkle, Eric; Ballantyne, Christie M.; Coresh, Josef

Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease

ALZHEIMERS & DEMENTIA

IF11.1

2023-02-15

OAAI

Shi, Liu; Xu, Jin; Green, Rebecca; Wretlind, Asger; Homann, Jan; Buckley, Noel J.; Tijms, Betty M.; Vos, Stephanie J. B.; Lill, Christina M.; ten Kate, Mara; Engelborghs, Sebastiaan; Sleegers, Kristel; Frisoni, Giovanni B.; Wallin, Anders; Lleo, Alberto; Popp, Julius; Martinez-Lage, Pablo; Streffer, Johannes; Barkhof, Frederik; Zetterberg, Henrik; Visser, Pieter Jelle; Lovestone, Simon; Bertram, Lars; Nevado-Holgado, Alejo J.; Proitsi, Petroula; Legido-Quigley, Cristina

Predicting progression to Alzheimer's disease with human hippocampal progenitors exposed to serum

BRAIN

IF11.7

2023-01-27

OAAI

Maruszak, Aleksandra; Silajdzic, Edina; Lee, Hyunah; Murphy, Tytus; Liu, Benjamine; Shi, Liu; de Lucia, Chiara; Douiri, Abdel; Salta, Evgenia; Nevado, Alejo J.; Teunissen, Charlotte E.; Visser, Pieter J.; Price, Jack; Zetterberg, Henrik; Lovestone, Simon; Thuret, Sandrine

Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2022-11-29

OAAI

Zhang, Yuting; Ghose, Upamanyu; Buckley, Noel J.; Engelborghs, Sebastiaan; Sleegers, Kristel; Frisoni, Giovanni B.; Wallin, Anders; Lleo, Alberto; Popp, Julius; Martinez-Lage, Pablo; Legido-Quigley, Cristina; Barkhof, Frederik; Zetterberg, Henrik; Visser, Pieter Jelle; Bertram, Lars; Lovestone, Simon; Nevado-Holgado, Alejo J.; Shi, Liu

Comparative effect of metformin versus sulfonylureas with dementia and Parkinson's disease risk in US patients over 50 with type 2 diabetes mellitus

BMJ OPEN DIABETES RESEARCH & CARE

IF4.1

2022-09-15

OAAI

Newby, Danielle; Linden, Andrew Brent; Fernandes, Marco; Molero, Yasmina; Winchester, Laura; Sproviero, William; Ghose, Upamanyu; Li, Qingqin S.; Launer, Lenore J.; van Duijn, Cornelia M.; Nevado-Holgado, Alejo J.

Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health

NATURE COMMUNICATIONS

IF15.7

2022-08-09

OAAI

Gadd, Danni A.; Hillary, Robert F.; McCartney, Daniel L.; Shi, Liu; Stolicyn, Aleks; Robertson, Neil A.; Walker, Rosie M.; McGeachan, Robert, I; Campbell, Archie; Xueyi, Shen; Barbu, Miruna C.; Green, Claire; Morris, Stewart W.; Harris, Mathew A.; Backhouse, Ellen, V; Wardlaw, Joanna M.; Steele, J. Douglas; Oyarzun, Diego A.; Muniz-Terrera, Graciela; Ritchie, Craig; Nevado-Holgado, Alejo; Chandra, Tamir; Hayward, Caroline; Evans, Kathryn L.; Porteous, David J.; Cox, Simon R.; Whalley, Heather C.; McIntosh, Andrew M.; Marioni, Riccardo E.

Genome- and epigenome-wide studies of plasma protein biomarkers for Alzheimer's disease implicate TBCA and TREM2 in disease risk

ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING

IF4.4

2022-04-20

OAAI

Hillary, Robert F.; Gadd, Danni A. A.; McCartney, Daniel L. L.; Shi, Liu; Campbell, Archie; Walker, Rosie M. M.; Ritchie, Craig W. W.; Deary, Ian J. J.; Evans, Kathryn L. L.; Nevado-Holgado, Alejo J. J.; Hayward, Caroline; Porteous, David J. J.; McIntosh, Andrew M. M.; Lovestone, Simon; Robinson, Matthew R. R.; Marioni, Riccardo E. E.

研究方向