未登录 Phase I study of bevacizumab and temsirolimus combination therapy in advanced malignancies: safety, efficacy, and ovarian cancer expansion 贝伐珠单抗和替西罗莫司联合疗法在晚期恶性肿瘤中的I期研究：安全性、有效性和卵巢癌扩展 Piha-Paul, Sarina A.; Tseng, Chieh; Thompson, Emily; Stafford, R. Jason; Le, Hung; Kang, Lei; Fu, Siqing; Tsimberidou, Apostolia; Blumenschein, George; Ahnert, Jordi Rodon; Slopis, John M.; Hong, David; Naing, Aung; Meric-Bernstam, Funda; Ng, Chaan S.; Westin, Shannon; Sood, Anil K. 分享 收藏
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Phase I/II Study of AXL-Specific Antibody-Drug Conjugate Enapotamab Vedotin in Patients with Advanced Solid Tumors 晚期实体瘤患者AXL特异性抗体药物偶联物Enapotamab Vedotin的I/II期研究 Rohrberg, Kristoffer Staal; Lopez, Juanita S.; Milhem, Mohammed M.; Blank, Christian U.; Reijers, Irene; Thistlethwaite, Fiona; Plummer, Ruth; Piha-Paul, Sarina A.; Janne, Pasi A.; Shum, Elaine; Shaw, Heather M.; Debruyne, Philip R.; Lao, Cristopher; Baurain, Jean-Francois; Choe, Jennifer H.; Gort, Eelke; Zhao, Yujie; Jerusalem, Guy; Schoffski, Patrick; Chen, Andrew William; Cohen, Eric A.; Mankowski, Walter C.; Roshkovan, Leonid; Katz, Sharyn I.; Kontos, Despina; Brady, Lauren K.; Qutaish, Mohammed; Castro, Patricia Garrido; Pencheva, Nora; Bajaj, Gaurav; Fu, Yali; Windfeld, Kristian; Reiter, Panagiota; Jure-Kunkel, Maria; Higgs, Brandon W.; Amiri, Katayoun I.; Ahmadi, Tahamtan; Forssmann, Ulf; Ramalingam, Suresh S.; Vergote, Ignace 分享 收藏
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Final results from the phase Ia/Ib study of the novel bromodomain and extra-terminal domain inhibitor, BI 894999, in patients with advanced solid tumors or diffuse large B-cell lymphoma 新型溴结构域和-extra-terminal结构域抑制剂BI 894999在晚期实体瘤或弥漫性大B细胞淋巴瘤患者中的Ia/Ib期研究最终结果 Lauer, U. M.; Awada, A.; Postel-Vinay, S.; Shapiro, G. I.; Thieblemont, C.; Piha-Paul, S. A.; Paik, P. K.; Shepard, D. R.; Docampo, L. I.; Galot, R.; Rottey, S.; Sadrolhefazi, B.; Marzin, K.; Musa, H.; Schoffski, P. 分享 收藏
Selinexor in combination with carboplatin and paclitaxel in patients with advanced solid tumors: results of a single-center, multi-arm phase Ib study (vol 40, pg 290, 2022) Thein, Kyaw Z.; Karp, Daniel D.; Tsimberidou, Apostolia; Gong, Jing; Sulovic, Selma; Shah, Jatin; Milton, Denai R.; Hong, David S.; Janku, Filip; Mcquinn, Lacey; Stephen, Bettzy A.; Colen, Rivka; Carter, Brett W.; Yap, Timothy A.; Piha-Paul, Sarina A.; Fu, Siqing; Meric-Bernstam, Funda; Naing, Aung 分享 收藏
A phase I study of temsirolimus in combination with metformin in patients with advanced or recurrent endometrial cancer 一项关于temsirolimus联合metformin治疗晚期或复发性子宫内膜癌的I期研究 Ahmed, Jibran; Stephen, Bettzy; Khawaja, Muhammad R.; Yang, Yali; Salih, Israa; Barrientos-Toro, Elizve; Raso, Maria Gabriela; Karp, Daniel D.; Piha-Pa, Sarina A.; Sood, Anil K.; Ng, Chaan S.; Johnson, Amber; Soliman, Pamela T.; Meric-Bernstam, Funda; Luc, Karen H.; Naing, Aung 分享 收藏
Phase I trial of the combination of the pan-ErbB inhibitor neratinib and mTOR inhibitor everolimus in advanced cancer patients with ErbB family gene alterations Piha-Paul, S. A.; Tseng, C.; Tran, H. T.; Naing, A.; Dumbrava, E. E.; Karp, D. D.; Rodon, J.; Yap, T. A.; Raghav, K. P.; Damodaran, S.; Le, X.; Soliman, P. T.; Lim, J.; Meric-Bernstam, F. 分享 收藏
A phase 2 basket study of talabostat, a small-molecule inhibitor of dipeptidyl peptidases, administered in combination with pembrolizumab in patients with advanced solid cancers Ahmed, Jibran; Janku, Filip; Karp, Daniel D.; Piha-Paul, Sarina A.; Tsimberidou, Apostolia M.; Yap, Timothy Anthony; Stephen, Bettzy; Yang, Yali; Gurses, Serdar; Liu, Qian; Song, Juhee; Meric-Bernstam, Funda; Naing, Aung 分享 收藏
A phase Ia study of a novel anti-HER2 antibody-drug conjugate GQ1001 in patients with previously treated HER2 positive advanced solid tumors 一种新型anti-HER2抗体药物偶联物GQ1001在先前治疗过的HER2阳性晚期实体瘤患者中的Ia期研究 Zhou, Chenfei; Wang, Bin; Teng, Christina; Yang, Hui; Piha-Paul, Sarina A.; Richardson, Gary; Malalasekera, Ashanya; Sun, Yajun; Wang, Wei; Liu, Jieqiong; Shi, Yan; Zhan, Xianbao; Lemech, Charlotte 分享 收藏
Clinical and biomarker data from a phase 1/2 trial of ifinatamab deruxtecan (I-DXd; DS-7300) in advanced solid tumors Doi, T.; Patel, M. R.; Koyama, T.; Falchook, G. S.; Friedman, C.; Piha-Paul, S. A.; Gutierrez, M.; Awad, M.; Mattour, A.; Satoh, T.; Takahashi, S.; Tsunoda, T.; Kadowaki, S.; Watanabe, Y.; Okamoto, N.; Goto, H.; Yoshizuka, N.; Qian, M.; Qian, X.; Johnson, M. 分享 收藏
Preliminary results from a phase I, first-in-human study of DS-9606a, a claudin 6 (CLDN6)-directed antibody-drug conjugate (ADC), in patients (pts) with tumor types known to express CLDN6 DS-9606a（一种靶向claudin 6 [CLDN6]的抗体偶联药物[ADC]）的I期首次人体研究的初步结果，该研究纳入了已知表达CLDN6的肿瘤类型的患者(pts)。 Patel, M. R.; Hamilton, E. P.; Piha-Paul, S. A.; Henry, J.; Banerji, U.; Al Hallak, M. N.; Okada, H.; Qian, M.; Zhang, X.; Said, N.; Chatikhine, V.; Fontana, E. 分享 收藏
Neratinib Alone or in Combination with Immune Checkpoint Inhibitors with or without Mammalian Target of Rapamycin Inhibitors in Patients with Fibrolamellar Carcinoma Abou-Alfa, Ghassan K.; Meyer, Tim; Do, Richard Kinh Gian; Piha-Paul, Sarina A.; Light, Joseph S.; Sherrin, Scott; Yaqubie, Amin; O'Neill, Alison Clemens; Harding, James J.; Al-Rajabi, Raed; Denlinger, Crystal S.; Cano, Pablo; Cornelius, Albert S.; O'Reilly, Eileen M.; Diprimeo, Daniel; Eli, Lisa D.; Gordan, John D.; Solit, David B. 分享 收藏
Phase II study of talazoparib in advanced cancers with BRCA1/2, DNA repair, and PTEN alterations talazoparib在具有BRCA1/2，DNA修复和PTEN改变的晚期癌症中的II期研究 Piha-Paul, Sarina A.; Tseng, Chieh; Leung, Cheuk Hong; Yuan, Ying; Karp, Daniel D.; Subbiah, Vivek; Hong, David; Fu, Siqing; Naing, Aung; Rodon, Jordi; Javle, Milind; Ajani, Jaffer A.; Raghav, Kanwal P.; Somaiah, Neeta; Mills, Gordon B.; Tsimberidou, Apostolia M.; Zheng, Xiaofeng; Chen, Ken; Meric-Bernstam, Funda 分享 收藏
A phase I study of TAK-659 and paclitaxel in patients with taxane-refractory advanced solid tumors 紫杉烷难治性晚期实体瘤患者TAK-659和紫杉醇的I期研究 Gouda, M. A.; Shunyakova, J.; Naing, A.; Dumbrava, E.; Hong, D. S.; Yuan, Y.; Yang, P.; Myers, A.; Liang, Y.; Peng, J.; Karp, D.; Tsimberidou, A. M.; Rodon, J.; Yap, T. A.; Piha-Paul, S. A.; Meric-Bernstam, F.; Fu, S. 分享 收藏
Tinengotinib in patients with advanced solid tumors harboring actionable FGFR1-3 mutations Piha-Paul, Sarina A.; Liao, Chih-Yi Andy; Fonkoua, Lionel; Mahipa, Amit, I; Goel, Sanjay; Fountzilas, Christos; Shen, Lin; Li, Daneng; Deming, Dustin; Dayyani, Farshid; Han, Weiqing; Niu, Zuoxing; Fan, Jean; Peng, Peng; Wang, Hui; Huang, Peng; Wu, Frank; Javle, Milind 分享 收藏
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